Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

European Journal of Medicinal Chemistry

Volumn 90, Issue , 2015, Pages 124-169

  Khan, Imtiaz ^a   Ibrar, Aliya ^b   Ahmed, Waqas ^c   Saeed, Aamer ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b QUAID I AZAM UNIVERSITY   (Pakistan)

^c UNIVERSITY OF GUJRAT   (Pakistan)

Author keywords

Bioactive heterocycles; Biological potential; Cross coupling reactions; Enzymes; Inhibitors; Synthetic methods

Indexed keywords

AFATINIB; AMPICILLIN; ASPERLICIN; CANERTINIB; CIRCUMDATIN F; DACOMITINIB; DOXORUBICIN; ERLOTINIB; FLUCONAZOLE; FLUOROURACIL; GEFITINIB; ISPINESIB; OXAZEPINE DERIVATIVE; OXAZINE DERIVATIVE; PHENYTOIN; POLYOXIN B; QUINAZOLINE DERIVATIVE; QUINAZOLINONE DERIVATIVE; RALTITREXED; RUTAECARPINE; SCLEROTIGENIN; STREPTOMYCIN; THEOPHYLLINE; UNCLASSIFIED DRUG; VANDETANIB; ANGIOGENESIS INHIBITOR; ANTIASTHMATIC AGENT; ANTICONVULSIVE AGENT; ANTIHISTAMINIC AGENT; ANTIHYPERTENSIVE AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIMALARIAL AGENT; ANTIMYCOBACTERIAL AGENT; ANTINEOPLASTIC AGENT; BRONCHODILATING AGENT; CHOLINESTERASE INHIBITOR; CYTOTOXIC AGENT; DIHYDROFOLATE REDUCTASE INHIBITOR; GLUTAMATE RECEPTOR AGONIST; GLYCOSIDASE INHIBITOR; GLYCOSYLTRANSFERASE INHIBITOR; INSECTICIDE; PEPTIDE HYDROLASE INHIBITOR; PHOSPHODIESTERASE INHIBITOR; PHOSPHOTRANSFERASE INHIBITOR; BETA GLUCURONIDASE; DIHYDROFOLATE REDUCTASE; ENZYME INHIBITOR; PHOSPHOTRANSFERASE;

ALKYNYLATION; AMIDATION; AMINATION; ANTIANGIOGENIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ANTIPROTOZOAL ACTIVITY; BRONCHODILATATION; CATALYSIS; COST EFFECTIVENESS ANALYSIS; CYCLIZATION; DRUG DESIGN; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; METHODOLOGY; NONHUMAN; ONE POT SYNTHESIS; REVIEW; ANNULATION REACTION; ANTICONVULSANT ACTIVITY; ANTIMICROBIAL ACTIVITY; AROMATIZATION; ARYLATION; ATMOSPHERIC PRESSURE; AUTOPHOSPHORYLATION; BIOLOGICAL ACTIVITY; CARBONYLATION; CATALYST; CHOLINESTERASE INHIBITION; CROSS COUPLING REACTION; CYCLOADDITION; CYTOTOXICITY; DRUG SYNTHESIS; ELECTRON TRANSPORT; ELECTROPHILICITY; ENANTIOSELECTIVITY; GREEN CHEMISTRY; HYDROGEN BOND; INSECTICIDAL ACTIVITY; MANNICH REACTION; MICHAEL ADDITION; MICROWAVE IRRADIATION; NUCLEOPHILICITY; OXIDATIVE COUPLING; REACTION TIME; STEREOSPECIFICITY; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; METABOLISM; SYNTHESIS;

ANGIOGENESIS INHIBITORS; ANTI-BACTERIAL AGENTS; ANTICONVULSANTS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; ENZYME INHIBITORS; GLUCURONIDASE; HUMANS; MOLECULAR STRUCTURE; PHOSPHOTRANSFERASES; QUINAZOLINES; QUINAZOLINONES; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84923880893     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.10.084     Document Type: Short Survey

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