Synthesis of newer thiadiazolyl and thiazolidinonyl quinazolin-4(3H)-ones as potential anticonvulsant agents

European Journal of Medicinal Chemistry

Volumn 37, Issue 11, 2003, Pages 873-882

  Archana, ^a   Srivastava, V K ^a   Kumar, Ashok ^a  

^a LLRM MEDICAL COLLEGE   (India)

Author keywords

Acute toxicity; Anticonvulsant activity; Thiadiazolyl quinazolin 4(3H) ones; Thiadiazolyl thiazolidinonyl quinazo lin 4(3H) ones

Indexed keywords

3 [[4 [2 (3 METHOXY 4 HYDROXYPHENYL) 4 OXO 1,3 THIAZOLIDIN 3 YL] 1,3,4 THIADIAZOL 2 YL]METHYLAMINO] 2 METHYL 6 BROMOQUINAZOLIN 4(3H) ONE; ALDEHYDE; ANTICONVULSIVE AGENT; LAMOTRIGINE; PHENYTOIN; QUINAZOLINE DERIVATIVE; THIADIAZOLE DERIVATIVE; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG; VALPROIC ACID; PENTOBARBITAL;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLOADDITION; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; INFRARED SPECTROSCOPY; MALE; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; ANIMAL; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; RAT STRAIN; SEIZURE; SLEEP; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTICONVULSANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; PENTOBARBITAL; QUINAZOLINES; RATS; RATS, INBRED STRAINS; SEIZURES; SLEEP; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 1842858323     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(02)01389-2     Document Type: Article

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