Novel EGFR inhibitors prepared by combination of dithiocarbamic acid esters and 4-anilinoquinazolines

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 12, 2011, Pages 3637-3640

  Li, Ri Dong ^a   Zhang, Xin ^a   Li, Qiao Yan ^a   Ge, Ze Mei ^a   Li, Run Tao ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

4 Anilinoquinazoline; Combination strategy; Dithiocarbamic acid ester; EGFR inhibitor; Synthesis

Indexed keywords

4 ANILINOQUINAZOLINE DERIVATIVE; ANTINEOPLASTIC AGENT; DITHIOCARBAMIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; LAPATINIB; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTERS; HUMANS; MOLECULAR STRUCTURE; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP; THIOCARBAMATES;

EID: 79957802327     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.096     Document Type: Article

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