메뉴 건너뛰기




Volumn 80, Issue , 2014, Pages 447-501

Quinazolines: New horizons in anticonvulsant therapy

Author keywords

Anticonvulsant; MES; PTZ induced seizure; Synthesis quinazoline

Indexed keywords

ANTICONVULSIVE AGENT; QUINAZOLINE DERIVATIVE;

EID: 84899832193     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.04.072     Document Type: Short Survey
Times cited : (162)

References (72)
  • 3
    • 84872067224 scopus 로고    scopus 로고
    • Novel approaches to epilepsy treatment
    • A.T. Sørensen, and M. Kokaia Novel approaches to epilepsy treatment Epilepsia 54 2013 1 10
    • (2013) Epilepsia , vol.54 , pp. 1-10
    • Sørensen, A.T.1    Kokaia, M.2
  • 4
    • 33646911656 scopus 로고    scopus 로고
    • New horizons in the development of antiepileptic drugs: Innovative strategies
    • W. Löscher, and D. Schmidt New horizons in the development of antiepileptic drugs: innovative strategies Epilepsy Research 69 2006 183 272
    • (2006) Epilepsy Research , vol.69 , pp. 183-272
    • Löscher, W.1    Schmidt, D.2
  • 5
    • 84862858037 scopus 로고    scopus 로고
    • Chemical properties of antiepileptic drugs (AEDs)
    • M. Bialer Chemical properties of antiepileptic drugs (AEDs) Advanced Drug Delivery Reviews 64 2012 887 895
    • (2012) Advanced Drug Delivery Reviews , vol.64 , pp. 887-895
    • Bialer, M.1
  • 6
    • 0042416551 scopus 로고    scopus 로고
    • Preclinical development of antiepileptic drugs: Past, present and future directions
    • H.S. White Preclinical development of antiepileptic drugs: past, present and future directions Epilepsia 44 Suppl. 7 2004 2 8
    • (2004) Epilepsia , vol.44 , Issue.SUPPL. 7 , pp. 2-8
    • White, H.S.1
  • 7
    • 0036345479 scopus 로고    scopus 로고
    • New strategies for the identification of drugs to prevent the development or progression of epilepsy
    • D. Schmidt, and M.A. Rogawski New strategies for the identification of drugs to prevent the development or progression of epilepsy Epilepsy Research 50 2002 71 78
    • (2002) Epilepsy Research , vol.50 , pp. 71-78
    • Schmidt, D.1    Rogawski, M.A.2
  • 8
    • 34547828792 scopus 로고    scopus 로고
    • Development of new antiepileptic drugs: Challenges, incentives, and recent advances
    • E. Perucca, J. French, and M. Bialer Development of new antiepileptic drugs: challenges, incentives, and recent advances The Lancet Neuro 6 2007 793 804
    • (2007) The Lancet Neuro , vol.6 , pp. 793-804
    • Perucca, E.1    French, J.2    Bialer, M.3
  • 9
    • 84855309027 scopus 로고    scopus 로고
    • Medicinal and biological significance of quinazoline: A highly important scaffold for drug discovery: A review
    • S. Manjula, E. Bharath, and B. Divya Medicinal and biological significance of quinazoline: a highly important scaffold for drug discovery: a review International Journal of Pharma and Bio Sciences 2 2011 780 809
    • (2011) International Journal of Pharma and Bio Sciences , vol.2 , pp. 780-809
    • Manjula, S.1    Bharath, E.2    Divya, B.3
  • 11
    • 79961078010 scopus 로고
    • Potential anticonvulsants synthesis of 2, 3-disubstituted-4- quinazolinones and quinazolino-4-thiones
    • A. Bhaduri, N. Khanna, and M. Dhar Potential anticonvulsants synthesis of 2, 3-disubstituted-4-quinazolinones and quinazolino-4-thiones Indian Journal of Chemistry 2 1964 159 166
    • (1964) Indian Journal of Chemistry , vol.2 , pp. 159-166
    • Bhaduri, A.1    Khanna, N.2    Dhar, M.3
  • 12
    • 0019199469 scopus 로고
    • Studies on synthesis of 6-Bromo-2, 3-disubstituted 4-quinazolinones and their thiones
    • M.Z.A. Badr, H.A.H. El-Sherief, and A.M. Mahmoud Studies on synthesis of 6-Bromo-2, 3-disubstituted 4-quinazolinones and their thiones Bulletin of the Chemical Society 53 1980 2389 2392
    • (1980) Bulletin of the Chemical Society , vol.53 , pp. 2389-2392
    • Badr, M.Z.A.1    El-Sherief, H.A.H.2    Mahmoud, A.M.3
  • 13
    • 84857356050 scopus 로고    scopus 로고
    • Design and synthesis of novel 7-aminoquinazoline derivatives: Antitumor and anticonvulsant activities
    • A.S. El-Azab, and K.E. ElTahir Design and synthesis of novel 7-aminoquinazoline derivatives: antitumor and anticonvulsant activities Bioorganic & Medicinal Chemistry Letters 22 2012 1879 1885
    • (2012) Bioorganic & Medicinal Chemistry Letters , vol.22 , pp. 1879-1885
    • El-Azab, A.S.1    Eltahir, K.E.2
  • 16
    • 44349140647 scopus 로고    scopus 로고
    • Synthesis and pharmacological investigation of novel 4-(4-ethyl phenyl)-1-substituted-4H-[1,2,4] triazolo [4,3-A]-quinazolin-5-ones as new class of H1-antihistaminic agents
    • V. Alagarsamy, V. Raja Solomon, P. Parthiban, K. Dhanabal, S. Murugesan, G. Saravanan, and G. Anjana Synthesis and pharmacological investigation of novel 4-(4-ethyl phenyl)-1-substituted-4H-[1,2,4] triazolo [4,3-a]-quinazolin-5-ones as new class of H1-antihistaminic agents Journal of Heterocyclic Chemistry 45 2008 709 715
    • (2008) Journal of Heterocyclic Chemistry , vol.45 , pp. 709-715
    • Alagarsamy, V.1    Raja Solomon, V.2    Parthiban, P.3    Dhanabal, K.4    Murugesan, S.5    Saravanan, G.6    Anjana, G.7
  • 17
    • 28844504998 scopus 로고    scopus 로고
    • Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: An observational study and review of the literature
    • J. Rosenberg, F. Gustafsson, S. Galatius, and P.R. Hildebrandt Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature Cardiovascular Drugs and Therapy 19 2005 301 306
    • (2005) Cardiovascular Drugs and Therapy , vol.19 , pp. 301-306
    • Rosenberg, J.1    Gustafsson, F.2    Galatius, S.3    Hildebrandt, P.R.4
  • 20
    • 84869088753 scopus 로고    scopus 로고
    • Synthesis and configurational assignment of 1,2-dihydroimidazo [5,1b] quinazoline-3,9-diones: Novel NMDA receptor antagonists
    • A. Váradi, P. Horváth, T. Kurtán, A. Mándi, G. Tóth, A. Gergely, and J. Kökösi Synthesis and configurational assignment of 1,2-dihydroimidazo [5,1b] quinazoline-3,9-diones: novel NMDA receptor antagonists Tetrahedron 68 2012 10365 10371
    • (2012) Tetrahedron , vol.68 , pp. 10365-10371
    • Váradi, A.1    Horváth, P.2    Kurtán, T.3    Mándi, A.4    Tóth, G.5    Gergely, A.6    Kökösi, J.7
  • 22
    • 0342679402 scopus 로고    scopus 로고
    • Characterization of potential NMDA and cholecystokinin antagonists I. Acid-base properties of 2-methyl-4-oxo-3H-quinazoline-3-alkyl-carboxylic acids at the molecular and submolecular levels
    • J. Almási, K. Takács-Novák, J. Kökösi, and B. Noszál Characterization of potential NMDA and cholecystokinin antagonists I. Acid-base properties of 2-methyl-4-oxo-3H-quinazoline-3-alkyl- carboxylic acids at the molecular and submolecular levels International Journal of Pharmaceutics 180 1999 1 11
    • (1999) International Journal of Pharmaceutics , vol.180 , pp. 1-11
    • Almási, J.1    Takács-Novák, K.2    Kökösi, J.3    Noszál, B.4
  • 23
    • 40949087674 scopus 로고    scopus 로고
    • Novel AMPA and kainate receptor antagonists containing the pyrazolo [1,5] quinazoline ring system: Synthesis and structure activity relationships
    • F. Varano, D. Catarzi, V. Colotta, O. Lenzi, G. Filacchioni, A. Galli, and C. Costagli Novel AMPA and kainate receptor antagonists containing the pyrazolo [1,5] quinazoline ring system: synthesis and structure activity relationships Bioorganic & Medicinal Chemistry 16 2008 2617 2626
    • (2008) Bioorganic & Medicinal Chemistry , vol.16 , pp. 2617-2626
    • Varano, F.1    Catarzi, D.2    Colotta, V.3    Lenzi, O.4    Filacchioni, G.5    Galli, A.6    Costagli, C.7
  • 24
    • 38149124185 scopus 로고    scopus 로고
    • Synthesis and CNS depressant activity of some novel 3-[5-substituted1,3, 4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones
    • V. Jatav, P. Mishra, S. Kashaw, and J. Stables Synthesis and CNS depressant activity of some novel 3-[5-substituted1,3,4-thiadiazole-2-yl]-2- styryl quinazoline-4(3H)-ones European Journal of Medicinal Chemistry 43 2008 135 141
    • (2008) European Journal of Medicinal Chemistry , vol.43 , pp. 135-141
    • Jatav, V.1    Mishra, P.2    Kashaw, S.3    Stables, J.4
  • 26
    • 0018675759 scopus 로고
    • Anticonvulsant and monoamine oxidase inhibitory properties of newer chlorostrylquinazolones
    • R. Misra, A. Chaturvedi, N. Rao, and S. Parmar Anticonvulsant and monoamine oxidase inhibitory properties of newer chlorostrylquinazolones Pharmacological Research Communications 11 1979 623 633
    • (1979) Pharmacological Research Communications , vol.11 , pp. 623-633
    • Misra, R.1    Chaturvedi, A.2    Rao, N.3    Parmar, S.4
  • 29
    • 77954298451 scopus 로고    scopus 로고
    • Pharmacological characterization of some selected 4,5-dihydro-4-oxo-1,2, 4-triazolo [1,5-A] quinoxaline-2-carboxylates and 3-hydroxyquinazoline-2,4- diones as (S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionic acid receptor antagonists
    • D. Catarzi, O. Lenzi, V. Colotta, F. Varano, D. Poli, G. Filacchioni, K. Lingenhöhl, and S. Ofner Pharmacological characterization of some selected 4,5-dihydro-4-oxo-1,2,4-triazolo [1,5-a] quinoxaline-2-carboxylates and 3-hydroxyquinazoline-2,4-diones as (S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4- yl)-propionic acid receptor antagonists Chemical & Pharmaceutical Bulletin 58 2010 908 911
    • (2010) Chemical & Pharmaceutical Bulletin , vol.58 , pp. 908-911
    • Catarzi, D.1    Lenzi, O.2    Colotta, V.3    Varano, F.4    Poli, D.5    Filacchioni, G.6    Lingenhöhl, K.7    Ofner, S.8
  • 31
    • 70449380842 scopus 로고    scopus 로고
    • Synthesis and evaluation on anticonvulsant and antidepressant activities of 5-alkoxy-tetrazolo [1,5-A] quinazolines
    • H.J. Wang, C.X. Wei, X.Q. Deng, F.L. Li, and Z.S. Quan Synthesis and evaluation on anticonvulsant and antidepressant activities of 5-alkoxy-tetrazolo [1,5-a] quinazolines Archives of Pharmacal Research 342 2009 671 675
    • (2009) Archives of Pharmacal Research , vol.342 , pp. 671-675
    • Wang, H.J.1    Wei, C.X.2    Deng, X.Q.3    Li, F.L.4    Quan, Z.S.5
  • 32
    • 0033857571 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant activity of acetylenic quinazolinone derivatives
    • C.O. Usifoh, and G.K. Scriba Synthesis and anticonvulsant activity of acetylenic quinazolinone derivatives Archives of Pharmacal Research 333 2000 261 266
    • (2000) Archives of Pharmacal Research , vol.333 , pp. 261-266
    • Usifoh, C.O.1    Scriba, G.K.2
  • 33
    • 84873734422 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant activity evaluation of 5-Phenyl-[1,2,4] triazolo[4,3-c]quinazolin-3-amines
    • Y. Zheng, M. Bian, X.Q. Deng, S.B. Wang, and Z.S. Quan Synthesis and anticonvulsant activity evaluation of 5-Phenyl-[1,2,4]triazolo[4,3-c]quinazolin- 3-amines Archives of Pharmacal Research 346 2012 119 126
    • (2012) Archives of Pharmacal Research , vol.346 , pp. 119-126
    • Zheng, Y.1    Bian, M.2    Deng, X.Q.3    Wang, S.B.4    Quan, Z.S.5
  • 34
    • 77954313825 scopus 로고    scopus 로고
    • Synthesis and biological screening of some new substituted 2-Mercapto-4-(3H)-quinazolinone analogs as anticonvulsant agents
    • A.A. Kadi, A.S. El-Azab, A.M. Alafeefy, and S. Abdel-Hamide Synthesis and biological screening of some new substituted 2-Mercapto-4-(3H)-quinazolinone analogs as anticonvulsant agents Arizona Journal of Pharmaceutical Science 34 2009 135 155
    • (2009) Arizona Journal of Pharmaceutical Science , vol.34 , pp. 135-155
    • Kadi, A.A.1    El-Azab, A.S.2    Alafeefy, A.M.3    Abdel-Hamide, S.4
  • 36
    • 0038166026 scopus 로고    scopus 로고
    • Design and synthesis of some new derivatives of 3H-quinazolin-4-one with promising anticonvulsant activity
    • A. El-Helby, and M. Wahab Design and synthesis of some new derivatives of 3H-quinazolin-4-one with promising anticonvulsant activity Acta Pharmaceutica 53 2003 127
    • (2003) Acta Pharmaceutica , vol.53 , pp. 127
    • El-Helby, A.1    Wahab, M.2
  • 38
    • 84859847666 scopus 로고    scopus 로고
    • Design, synthesis and anticonvulsant activities of novel 1-(substituted/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl/phenyl)-4- oxoquinazolin-3(4H)-yl)phenyl) semicarbazide derivatives
    • G. Saravanan, V. Alagarsamy, and C.R. Prakash Design, synthesis and anticonvulsant activities of novel 1-(substituted/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl/phenyl)-4-oxoquinazolin-3(4H)-yl) phenyl) semicarbazide derivatives Bioorganic & Medicinal Chemistry Letters 22 2012 3072 3078
    • (2012) Bioorganic & Medicinal Chemistry Letters , vol.22 , pp. 3072-3078
    • Saravanan, G.1    Alagarsamy, V.2    Prakash, C.R.3
  • 39
    • 0036924308 scopus 로고    scopus 로고
    • Dictyoquinazols A, B, and C, new neuroprotective compounds from the mushroom Dictyophora indusiata
    • I.-K. Lee, B.-S. Yun, G. Han, D.-H. Cho, Y.-H. Kim, and I.-D. Yoo Dictyoquinazols A, B, and C, new neuroprotective compounds from the mushroom Dictyophora indusiata Journal of Natural Products 65 2002 1769 1772
    • (2002) Journal of Natural Products , vol.65 , pp. 1769-1772
    • Lee, I.-K.1    Yun, B.-S.2    Han, G.3    Cho, D.-H.4    Kim, Y.-H.5    Yoo, I.-D.6
  • 42
    • 0014263667 scopus 로고
    • Drugs acting on the central nervous system. Syntheses of substituted quinazolinones and quinazolines and triazepino-triazocinoquinazolinones
    • C. Gupta, A. Bhaduri, and N. Khanna Drugs acting on the central nervous system. Syntheses of substituted quinazolinones and quinazolines and triazepino-triazocinoquinazolinones Journal of Medicinal Chemistry 11 1968 392 395
    • (1968) Journal of Medicinal Chemistry , vol.11 , pp. 392-395
    • Gupta, C.1    Bhaduri, A.2    Khanna, N.3
  • 44
    • 0021260947 scopus 로고
    • Synthesis of previously inaccessible quinazolines and 1,4-benzodiazepines as potential anticonvulsants
    • A.A. Fatmi, N.A. Vaidya, W. Iturrian, and C.D. Blanton Jr. Synthesis of previously inaccessible quinazolines and 1,4-benzodiazepines as potential anticonvulsants Journal of Medicinal Chemistry 27 1984 772 778
    • (1984) Journal of Medicinal Chemistry , vol.27 , pp. 772-778
    • Fatmi, A.A.1    Vaidya, N.A.2    Iturrian, W.3    Blanton, Jr.C.D.4
  • 45
    • 0037186487 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of a new set of pyrazolo [1,5-c] quinazoline-2-carboxylates as novel excitatory amino acid antagonists
    • F. Varano, D. Catarzi, V. Colotta, G. Filacchioni, A. Galli, C. Costagli, and V. Carlà Synthesis and biological evaluation of a new set of pyrazolo [1,5-c] quinazoline-2-carboxylates as novel excitatory amino acid antagonists Journal of Medicinal Chemistry 45 2002 1035 1044
    • (2002) Journal of Medicinal Chemistry , vol.45 , pp. 1035-1044
    • Varano, F.1    Catarzi, D.2    Colotta, V.3    Filacchioni, G.4    Galli, A.5    Costagli, C.6    Carlà, V.7
  • 47
    • 33749328794 scopus 로고    scopus 로고
    • Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4- dione scaffold to obtain AMPA and kainate receptor selective antagonists. Synthesis, pharmacological, and molecular modeling studies
    • V. Colotta, D. Catarzi, F. Varano, O. Lenzi, G. Filacchioni, C. Costagli, A. Galli, C. Ghelardini, N. Galeotti, and P. Gratteri Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4-dione scaffold to obtain AMPA and kainate receptor selective antagonists. synthesis, pharmacological, and molecular modeling studies Journal of Medicinal Chemistry 49 2006 6015 6026
    • (2006) Journal of Medicinal Chemistry , vol.49 , pp. 6015-6026
    • Colotta, V.1    Catarzi, D.2    Varano, F.3    Lenzi, O.4    Filacchioni, G.5    Costagli, C.6    Galli, A.7    Ghelardini, C.8    Galeotti, N.9    Gratteri, P.10
  • 48
    • 0029954302 scopus 로고    scopus 로고
    • Synthesis and binding activity of some pyrazolo [1, 5-c] quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand
    • V. Colotta, D. Catarzi, F. Varano, G. Filacchioni, L. Cecchi, A. Galli, and C. Costagli Synthesis and binding activity of some pyrazolo [1, 5-c] quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand Journal of Medicinal Chemistry 39 1996 2915 2921
    • (1996) Journal of Medicinal Chemistry , vol.39 , pp. 2915-2921
    • Colotta, V.1    Catarzi, D.2    Varano, F.3    Filacchioni, G.4    Cecchi, L.5    Galli, A.6    Costagli, C.7
  • 52
    • 77954313516 scopus 로고    scopus 로고
    • Synthesis of some new 4-(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities part-1
    • M.M. Aly, Y.A. Mohamed, K.A. El-Bayouki, W.M. Basyouni, and S.Y. Abbas Synthesis of some new 4-(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities part-1 European Journal of Medicinal Chemistry 45 2010 3365 3373
    • (2010) European Journal of Medicinal Chemistry , vol.45 , pp. 3365-3373
    • Aly, M.M.1    Mohamed, Y.A.2    El-Bayouki, K.A.3    Basyouni, W.M.4    Abbas, S.Y.5
  • 53
    • 79952283259 scopus 로고    scopus 로고
    • Design, synthesis and potential 6 Hz psychomotor seizure test activity of some novel 2-(substituted)-3-[substituted]aminoquinazolin-4(3H)-one
    • P. Kumar, B. Shrivastava, S.N. Pandeya, and J.P. Stables Design, synthesis and potential 6 Hz psychomotor seizure test activity of some novel 2-(substituted)-3-[substituted]aminoquinazolin-4(3H)-one European Journal of Medicinal Chemistry 46 2011 1006 1018
    • (2011) European Journal of Medicinal Chemistry , vol.46 , pp. 1006-1018
    • Kumar, P.1    Shrivastava, B.2    Pandeya, S.N.3    Stables, J.P.4
  • 54
    • 15944377918 scopus 로고    scopus 로고
    • Quinazolines revisited: Search for novel anxiolytic and GABAergic agents
    • R. Goel, V. Kumar, and M. Mahajan Quinazolines revisited: search for novel anxiolytic and GABAergic agents Bioorganic & Medicinal Chemistry Letters 15 2005 2145 2148
    • (2005) Bioorganic & Medicinal Chemistry Letters , vol.15 , pp. 2145-2148
    • Goel, R.1    Kumar, V.2    Mahajan, M.3
  • 55
    • 70349770548 scopus 로고    scopus 로고
    • Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)- urea
    • S.K. Kashaw, V. Kashaw, P. Mishra, N. Jain, and J. Stables Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea European Journal of Medicinal Chemistry 44 2009 4335 4343
    • (2009) European Journal of Medicinal Chemistry , vol.44 , pp. 4335-4343
    • Kashaw, S.K.1    Kashaw, V.2    Mishra, P.3    Jain, N.4    Stables, J.5
  • 56
    • 81855202037 scopus 로고    scopus 로고
    • Design and synthesis of new derivatives of 3H-Quinazolin-4-one as potential anticonvulsant agents
    • U. Kabra, C. Chopde, and S. Wadodkar Design and synthesis of new derivatives of 3H-Quinazolin-4-one as potential anticonvulsant agents Journal of Heterocyclic Chemistry 48 2011 1351
    • (2011) Journal of Heterocyclic Chemistry , vol.48 , pp. 1351
    • Kabra, U.1    Chopde, C.2    Wadodkar, S.3
  • 57
    • 50949089653 scopus 로고    scopus 로고
    • CNS depressant and anticonvulsant activities of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones
    • V. Jatav, P. Mishra, S. Kashaw, and J. Stables CNS depressant and anticonvulsant activities of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl] -2-styryl quinazoline-4(3H)-ones European Journal of Medicinal Chemistry 43 2008 1945 1954
    • (2008) European Journal of Medicinal Chemistry , vol.43 , pp. 1945-1954
    • Jatav, V.1    Mishra, P.2    Kashaw, S.3    Stables, J.4
  • 59
    • 79952911675 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant activity of 6,7,8,9-tetrahydro-5H-5- (2′-hydroxy phenyl)-2-(4′-substituted benzylidine)-3-(4-nitrophenyl amino) thiazolo quinazoline derivatives
    • T. Panneerselvam, P.V. Kumar, C.R. Prakash, and S. Raja Synthesis and anticonvulsant activity of 6,7,8,9-tetrahydro-5H-5-(2′-hydroxy phenyl)-2-(4′-substituted benzylidine)-3-(4-nitrophenyl amino) thiazolo quinazoline derivatives Toxicological & Environmental Chemistry 93 2011 643 655
    • (2011) Toxicological & Environmental Chemistry , vol.93 , pp. 643-655
    • Panneerselvam, T.1    Kumar, P.V.2    Prakash, C.R.3    Raja, S.4
  • 60
    • 55249110578 scopus 로고    scopus 로고
    • Synthesis and anticonvulsant activity of some quinazolin-4-(3H)-one derivatives
    • H. Georgey, N. Abdel-Gawad, and S. Abbas Synthesis and anticonvulsant activity of some quinazolin-4-(3H)-one derivatives Molecules 13 2008 2557 2569
    • (2008) Molecules , vol.13 , pp. 2557-2569
    • Georgey, H.1    Abdel-Gawad, N.2    Abbas, S.3
  • 62
    • 84880019657 scopus 로고    scopus 로고
    • Design and synthesis of some 3-Substituted-2-[(2,4-dichlorophenoxy)- methyl] quinazolin-4(3H)-one derivatives as potential anticonvulsant agents
    • S.-S. Abbas, F.M. Awadallah, N.A. Ibrahim, E.G. Said, and G. Kamel Design and synthesis of some 3-Substituted-2-[(2,4-dichlorophenoxy)-methyl] quinazolin-4(3H)-one derivatives as potential anticonvulsant agents Chemical & Pharmaceutical Bulletin 61 2012 679 687
    • (2012) Chemical & Pharmaceutical Bulletin , vol.61 , pp. 679-687
    • Abbas, S.-S.1    Awadallah, F.M.2    Ibrahim, N.A.3    Said, E.G.4    Kamel, G.5
  • 63
    • 84875917035 scopus 로고    scopus 로고
    • Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4 (1H,3H)-dione derivatives to bovine serum albumin: A structure-activity relationship study
    • M. Prashanth, M. Madaiah, H. Revanasiddappa, and B. Veeresh Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4 (1H,3H)-dione derivatives to bovine serum albumin: a structure-activity relationship study Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy 110 2013 324 333
    • (2013) Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy , vol.110 , pp. 324-333
    • Prashanth, M.1    Madaiah, M.2    Revanasiddappa, H.3    Veeresh, B.4
  • 64
    • 68149141465 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of a new set of pyrazolo [1,5-c] quinazolines as glycine/N-methyl-D-aspartic acid receptor antagonists
    • F. Varano, D. Catarzi, V. Colotta, D. Poli, G. Filacchioni, A. Galli, and C. Costagli Synthesis and biological evaluation of a new set of pyrazolo [1,5-c] quinazolines as glycine/N-methyl-D-aspartic acid receptor antagonists Chemical & Pharmaceutical Bulletin 57 2009 826 829
    • (2009) Chemical & Pharmaceutical Bulletin , vol.57 , pp. 826-829
    • Varano, F.1    Catarzi, D.2    Colotta, V.3    Poli, D.4    Filacchioni, G.5    Galli, A.6    Costagli, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.