Design, synthesis, and antibacterial activity of novel Schiff base derivatives of quinazolin-4(3H)-one

European Journal of Medicinal Chemistry

Volumn 77, Issue , 2014, Pages 65-74

  Wang, Xiang ^a,b   Yin, Juan ^a   Shi, Li ^a   Zhang, Guoping ^a   Song, Baoan ^a  

^a GUIZHOU UNIVERSITY   (China)

^b Kaili University   (China)

Author keywords

Antibacterial activity; Quinazolin 4(3H) one; Ralstonia solanacearum; Schiff base derivative; Synthesis

Indexed keywords

2 [(4 CHLOROPHENYL)AMINO] 3 [2 ((3 NITROBENZYLIDENE) AMINO)ETHYL]QUINAZOLIN 4(3H) ONE; 3 (2 ((2 CHLOROBENZYLIDENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 (2 ((2 FLUOROBENZYLIDENE)AMINO)ETHYL) 2 (4 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 (2 ((2 FLUOROBENZYLIDENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 (2 ((2 HYDROXY 5 METHOXYBENZYLIDENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 (2 ((2 HYDROXY 5 METHYLBENZYLIDENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 (2 ((3,4 DICHLOROBENZYLIDENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 (2 ((4 (DIMETHYLAMINO)BENZYLIDENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 (2 ((4 BROMOBENZYLIDENE)AMINO)ETHYL) 2 (4 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 (2 ((NAPHTHALEN 1 YLMETHYLENE)AMINO)ETHYL) 2 (4 METHYLANILINO)QUINAZOLIN 4 (3H) ONE; 3 (2 ((NAPHTHALEN 1 YLMETHYLENE)AMINO)ETHYL) 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 AMINOETHYL 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 AMINOETHYL 2 [4 CHLORINEANILINO]QUINAZOLIN 4(3H) ONE; 3 AMINOETHYL 2 [4 METHYLANILINO]QUINAZOLIN 4(3H) ONE; 3 [2 ((2 NITROBENZYLIDENE)AMINO)ETHYL] 2 (4 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((2,6 DICHLOROBENZYLIDENE)AMINO)ETHYL] 2 (3 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((2,6 DICHLOROBENZYLIDENE)AMINO)ETHYL] 2 ANILINOQUINAZOLIN 4(3H) ONE; 3 [2 ((3 HYDROXY 4 METHOXYBENZYLIDENE)AMINO)ETHYL] 2 (4 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((3 NITROBENZYLIDENE)AMINO)ETHYL] 2 (4 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((4 (DIMETHYLAMINO)BENZYLIDENE)AMINO)ETHYL] 2 (3 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((4 CHLORO 3 NITROBENZYLIDENE)AMINO)ETHYL] 2 [(4 CHLOROPHENYL)AMINO]QUINAZOLIN 4(3H) ONE; 3 [2 ((4 CHLOROBENZYLIDENE)AMINO)ETHYL] 2 (4 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((4 FLUOROBENZYLIDENE)AMINO)ETHYL] 2 (3 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 ((4 HYDROXYBENZYLIDENE)AMINO)ETHYL] 2 (3 METHYLANILINO)QUINAZOLIN 4(3H) ONE; 3 [2 (BENZYLIDENEAMINO)ETHYL] 2 [(4 CHLOROPHENYL) AMINO]QUINAZOLIN 4(3H) ONE; 4(3H) QUINAZOLINONE DERIVATIVE; ANTIINFECTIVE AGENT; IMINE; SCHIFF BASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; QUINAZOLINONE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL WILT; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; DRUG DESIGN; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; TOBACCO; TOMATO; X RAY CRYSTALLOGRAPHY; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; RALSTONIA SOLANACEARUM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; LYCOPERSICON ESCULENTUM; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUINAZOLINONES; RALSTONIA SOLANACEARUM; SCHIFF BASES; STRUCTURE-ACTIVITY RELATIONSHIP; TOBACCO;

EID: 84895817561     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.02.053     Document Type: Article

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