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Volumn 347, Issue 9, 2014, Pages 650-657

Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: Design, synthesis, and docking studies

(5) Abdel Rahman, Hamdy M a Abdel Aziz, Mohamed b Canzoneri, Joshua C c Gary, Bernard D c Piazza, Gary A c

a Assiut University (Egypt)

b Minia University (Egypt)

c UNIVERSITY OF SOUTH ALABAMA (United States)

Author keywords

Antiproliferative; Docking; Hybrids; PDE4B inhibitors; Quinazolin 4(3H) one

Indexed keywords

ANTINEOPLASTIC AGENT; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; QUINAZOLINONE DERIVATIVE; SCHIFF BASE;

CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; HUMAN; IC50; METABOLISM; MOLECULAR DOCKING; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; PHOSPHODIESTERASE 4 INHIBITORS; QUINAZOLINONES; SCHIFF BASES;

EID: 84906826245 PISSN: 03656233 EISSN: 15214184 Source Type: Journal
DOI: 10.1002/ardp.201400083 Document Type: Article

Times cited : (15)

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