Design, synthesis and docking studies of bischalcones based quinazoline-2(1H)-ones and quinazoline-2(1H)-thiones derivatives as novel inhibitors of cathepsin B and cathepsin H

European Journal of Pharmaceutical Sciences

Volumn 54, Issue 1, 2014, Pages 28-39

  Raghav, Neera ^a   Singh, Mamta ^a  

^a KURUKSHETRA UNIVERSITY   (India)

Author keywords

Bischalcones and their quinazoline 2(1H) one and quinazoline 2(1H) thione derivative; Cancer progression; Cathepsin B; Cathepsin H; Non peptidyl inhibitors

Indexed keywords

CATHEPSIN B; CATHEPSIN H; CHALCONE DERIVATIVE; QUINAZOLINE DERIVATIVE; QUINAZOLINONE DERIVATIVE;

ARTICLE; CANCER GROWTH; COMPUTER MODEL; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; TUMOR INVASION;

BISCHALCONES AND THEIR QUINAZOLINE-2(1H)-ONE AND QUINAZOLINE-2(1H)-THIONE DERIVATIVE; CANCER PROGRESSION; CATHEPSIN B; CATHEPSIN H; NON-PEPTIDYL INHIBITORS;

ANIMALS; BRAIN; CATHEPSIN B; CATHEPSIN H; CHALCONES; DRUG DESIGN; ENZYME INHIBITORS; GOATS; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; QUINAZOLINES; QUINAZOLINONES; STRUCTURE-ACTIVITY RELATIONSHIP; THIONES;

EID: 84893117165     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.12.018     Document Type: Article

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