Adenosine monophosphate -activated kinase and its key role in catabolism: Structure, regulation, biological activity, and pharmacological activation

Molecular Pharmacology

Volumn 87, Issue 3, 2015, Pages 363-377

  Krishan, Sukriti ^a   Richardson, Des R ^a   Sahni, Sumit ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE BETA; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE LKB1; RESVERATROL; SALICYLIC ACID DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; ENZYME ACTIVATOR; METFORMIN;

AUTOPHAGY; CATABOLISM; DEGENERATIVE DISEASE; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME REGULATION; ENZYME STRUCTURE; GLUCOSE TRANSPORT; HUMAN; METABOLIC DISORDER; NEOPLASM; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; WOLFF PARKINSON WHITE SYNDROME; ANIMAL; CHEMISTRY; DRUG EFFECTS; ENERGY METABOLISM; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ENERGY METABOLISM; ENZYME ACTIVATORS; HOMEOSTASIS; HUMANS; METABOLISM; METFORMIN; PROTEIN STRUCTURE, SECONDARY; SIGNAL TRANSDUCTION;

EID: 84921289580     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.095810     Document Type: Review

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