The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex

Molecular and Cellular Biology

Volumn 17, Issue 4, 1997, Pages 2099-2106

  Jiang, Rong ^a   Carlson, Marian ^a,b  

^a Columbia University ^*  (United States)

^b HHSC 922 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; PROTEIN SERINE THREONINE KINASE;

ARTICLE; ENZYME ACTIVATION; GENETIC CONSERVATION; GLUCOSE METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TARGETING; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; YEAST;

SACCHAROMYCES CEREVISIAE;

EID: 0030953974     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.4.2099     Document Type: Article

References (45)

1. Aguan, K., J. Scott, C. G. See, and N. Sarkar. 1994. Characterization and chromosomal localization of the human homologue of a rat AMP-activated protein kinase-encoding gene: a major regulator of lipid metabolism in mammals. Gene 149:345-350.
2. Alderson, A., P. A. Sabelli, J. R. Dickinson, D. Cole, M. Richardson, M. Kreis, P. R. Shewry, and N. G. Halford. 1991. Complementation of snf1, a mutation affecting global regulation of carbon metabolism in yeast, by a plant protein kinase cDNA. Proc Natl. Acad. Sci. USA 88:8602-8605.
3. Carling, D., K. Aguan, A. Woods, A. J. M. Verhoeven, R. K. Beri, C. H. Brennan, C. Sidebottom, M. D. Davison, and J. Scott. 1994. Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism. J. Biol. Chem. 289:11442-11448.
4. Celenza, J. L., and M. Carlson. 1989. Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein. Mol. Cell. Biol. 9:5034-5044.
5. Celenza, J. L., and M. Carlson. 1986. A yeast gene that is essential for release from glucose repression encodes a protein kinase. Science 233:1175-1180.
6. Celenza, J. L., F. J. Eng, and M. Carlson. 1989. Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: evidence for physical association of the SNF4 protein with the SNF1 protein kinase. Mol. Cell. Biol. 9:5045-5054.
7. Chien, C., P. L. Bartel, R. Sternglanz, and S. Fields. 1991. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88:9578-9582.
8. Corton, J. M., J. G. Gillespie, and D. G. Hardie. 1994. Role of the AMP-activated protein kinase in the cellular stress response. Curr. Biol. 4:315-324.
9. Dale, S., W. Wilson, A. Edelman, and D. G. Hardie. 1995. Similar substrate recognition motifs for mammalian AMP-activated protein kinase, higher plant HMG-CoA reductase kinase-A, yeast SNF1, and mammalian calmodulin-dependent protein kinase I. FEBS Lett. 361:191-195.
10. Erickson, J. R., and M. Johnston. 1993. Genetic and molecular characterization of GAL83: its interaction and similarities with other genes involved in glucose repression in Saccharomyces cerevisiae. Genetics 135:655-664.
11. Estruch, F., M. A. Treitel, X. Yang, and M. Carlson. 1992. N-terminal mutations modulate yeast SNF1 protein kinase function. Genetics 132:639-650.
12. Fields, S., and O. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature 340:245-246.
13. Frangioni, J. V., and B. G. Neel. 1993. Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal. Biochem. 210:179-187.
14. Gao, G., J. Widmer, D. Stapleton, T. Teh, T. Cox, B. Kemp, and L. Witters. 1995. Catalytic subunits of the porcine and rat 5′-AMP-activated protein kinase are members of the SNF1 protein kinase family. Biochim. Biophys. Acta 1266:73-82.
15. Goffrini, P., A. Ficarelli, C. Donnini, T. Lodi, P. P. Puglisi, and I. Ferrero. 1996. FOG1 and FOG2 genes, required for the transcriptional activation of glucose-repressible genes of Kluyveromyces lactis, are homologous to GAL83 and SNF1 of Saccharomyces cerevisiae. Curr. Genet. 29:316-326.
16. Guo, S., and K. J. Kemphues. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative ser/thr kinase that is asymmetrically distributed. Cell 81:611-620.
17. Halford, N. G., J. Vicente-Carbajosa, P. A. Sabelli, P. R. Shewry, U. Hannappel, and M. Kreis. 1992. Molecular analyses of a barley multigene family homologous to the yeast protein kinase gene SNF1. Plant J. 2:791-797.
18. Hanes, S. D., and R. Brent. 1989. DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell 57:1275-1283.
19. Hanks, S. K., and T. Hunter. 1995. The eucaryotic protein kinase superfamily, p. 7-47. In G. Hardie and S. Hanks (ed.), The protein kinase factsbook: protein-serine kinases. Academic Press Inc., San Diego, Calif.
20. Hardie, D. G. 1992. Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase. Biochim. Biophys. Acta 1123:231-238.
21. Hardie, D. G. 1994. Ways of coping with stress. Nature 370:599-600.
22. Hubbard, E. J. A., R. Jiang, and M. Carlson. 1994. Dosage-dependent modulation of glucose repression by MSN3 (STD1) in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:1972-1978.
23. Jiang, R., and M. Carlson. 1996. Glucose regulates protein interactions within the yeast SNF1 protein kinase complex. Genes Dev. 10:3105-3115.
24. Legrain, P., M.-C. Dokhelar, and C. Transy. 1994. Detection of protein-protein interactions using different vectors in the two-hybrid system. Nucleic Acids Res. 22:3241-3242.
25. Le Guen, L., M. Thomas, M. Bianchi, N. G. Halford, and M. Kreis. 1992. Structure and expression of a gene from Arabidopsis thaliana encoding a protein related to SNF1 protein kinase. Gene 120:249-254.
26. Ludin, K., and M. Carlson. Unpublished results.
27. Matsumoto, K., A. Toh-E, and Y. Oshima. 1981. Isolation and characterization of dominant mutations resistant to carbon catabolite repression of galactokinase in Saccharomyces cerevisiae. Mol. Cell. Biol. 1:19-32.
28. Mitchelhill, K. I., D. Stapleton, G. Gao, C. House, B. Michell, F. Katsis, L. A. Witters, and B. E. Kemp. 1994. Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase. J. Biol. Chem. 269:2361-2364.
29. Muranaka, T., H. Banno, and Y. Machida. 1994. Characterization of tobacco protein kinase NPK5, a homolog of Saccharomyces cerevisiae SNF1 that constitutively activates expression of the glucose-repressible SUC2 gene for a secreted invertase of S. cerevisiae. Mol. Cell. Biol. 14:2958-2965.
30. Mylin, L. M., V. L. Bushman, R. M. Long, X. Yu, C. M. Lebo, T. E. Blank, and J. E. Hopper. 1994. SIP1 is a catabolite repression-specific negative regulator of GAL gene expression. Genetics 137:689-700.
31. Rose, M. D., F. Winston, and P. Hieter. 1990. Methods in yeast genetics: a laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
32. Ruden, D. M., J. Ma, Y. Li, K. Wood, and M. Ptashne. 1991. Generating yeast transcriptional activators containing no yeast protein sequences. Nature 350:250-252.
33. Ruiz, J., F. Conlon, and E. Robertson. 1994. Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. Mech. Dev. 48:153-164.
34. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
35. Schuller, H.-J., and K.-D. Entian. 1987. Isolation and expression analysis of two yeast regulatory genes involved in the derepression of glucose-repressible enzymes. Mol. Gen. Genet. 209:366-373.
36. Schuller, H.-J., and K.-D. Entian. 1988. Molecular characterization of yeast regulatory gene CAT3 necessary for glucose derepression and nuclear localization of its product. Gene 67:247-257.
37. Simon, M., M. Binder, G. Adam, A. Hartig, and H. Ruis. 1992. Control of peroxisome proliferation in Saccharomyces cerevisiae by ADR1, SNF1 (CAT1, CCR1) and SNF4 (CAT3). Yeast 8:303-309.
38. Stapleton, D., G. Gao, B. Michell, J. Widmer, K. Mitchehill, T. Teh, C. House, L. Witters, and B. Kemp. 1994. Mammalian 5′-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. J. Biol. Chem. 269:29343-29346.
39. Thompson-Jaeger, S., J. Francois, J. P. Gaughran, and K. Tatchell. 1991. Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway. Genetics 129:697-706.
40. Woods, A., P. C. Cheung, F. C. Smith, M. D. Davison, J. Scott, R. K. Beri, and D. Carling. 1996. Characterization of AMP-activated protein kinase β and γ subunits. J. Biol. Chem. 271:10282-10290.
41. Woods, A., M. R. Munday, J. Scott, X. Yang, M. Carlson, and D. Carling. 1994. Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. J. Biol. Chem. 269:19509-19516.
42. Xue, Z., and T. Melese. Unpublished data.
43. Yang, X. 1994. Ph.D. dissertation. Columbia University, New York, N.Y.
44. Yang, X., E. J. A. Hubbard, and M. Carlson. 1992. A protein kinase substrate identified by the two-hybrid system. Science 257:680-682.
45. Yang, X., R. Jiang, and M. Carlson. 1994. A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex. EMBO J. 13:5878-5886.