Whole body deletion of AMP-activated protein kinase β2 reduces muscle AMPK activity and exercise capacity

Journal of Biological Chemistry

Volumn 285, Issue 48, 2010, Pages 37198-37209

  Steinberg, Gregory R ^a,b   O'Neill, Hayley M ^a,b   Dzamko, Nicolas L ^b   Galic, Sandra ^b   Naim, Tim ^b   Koopman, René ^b   Jørgensen, Sebastian B ^b,c   Honeyman, Jane ^b   Hewitt, Kimberly ^b   Chen, Zhi Ping ^b   Schertzer, Jonathan D ^a,b   Scott, John W ^b   Koentgen, Frank ^d   Lynch, Gordon S ^b   Watt, Matthew J ^e   Van Denderen, Bryce J W ^b   Campbell, Duncan J ^b   Kemp, Bruce E ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c NOVO NORDISK A S   (Denmark)

^d Ozgene Pty Ltd   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE; AMPK ACTIVITY; C57BL/6 MICE; CARBOHYDRATE-BINDING MODULES; CARBOXAMIDES; DIET-INDUCED OBESITY; ENDURANCE EXERCISE; FATTY ACID OXIDATION; GERMLINE; GLUCOSE INTOLERANCE; GLUCOSE UPTAKE; HIGH-FAT DIET; INSULIN RESISTANCE; ISOFORMS; METABOLIC CONTROL; MUSCLE CONTRACTIONS; RIBONUCLEOTIDES; SKELETAL MUSCLE; UP-REGULATION; WHOLE BODY;

CARBOHYDRATES; FATTY ACIDS; GLUCOSE; LIVER; MUSCLE; NUTRITION; OXIDATION;

ENZYME ACTIVITY;

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; AMP ACTIVATED PROTEIN KINASE ALPHA1; AMP ACTIVATED PROTEIN KINASE ALPHA2; AMP ACTIVATED PROTEIN KINASE BETA2; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; ISOENZYME; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENDURANCE; ENZYME ACTIVITY; FATTY ACID OXIDATION; GENE DELETION; GERM LINE; GLUCOSE INTOLERANCE; GLUCOSE TRANSPORT; GLYCOGEN LIVER LEVEL; HYPERINSULINEMIA; INSULIN RESISTANCE; KNOCKOUT MOUSE; MALE; MOUSE; MUSCLE CONTRACTION; MUSCLE LEVEL; NONHUMAN; PHYSICAL CAPACITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREADMILL EXERCISE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; FATTY ACIDS; FEMALE; GENE DELETION; GLUCOSE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL;

MUS;

EID: 78549272729     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.102434     Document Type: Article

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