AMPK is abnormally activated in tangle-and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies

Acta Neuropathologica

Volumn 121, Issue 3, 2011, Pages 337-349

  Vingtdeux, Valérie ^a   Davies, Peter ^a,b   Dickson, Dennis W ^c   Marambaud, Philippe ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Alzheimer's disease; AMPK; Tangles; Tau; Tauopathies

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; POLYCLONAL ANTIBODY; SERINE; TAU PROTEIN; THREONINE;

ADULT; AGED; ALZHEIMER DISEASE; AMYLOID PLAQUE; ARGYROPHILIC GRAIN DISEASE; ARTICLE; BASAL GANGLION; BIOACCUMULATION; BRAIN NERVE CELL; CELL NUCLEUS; CHROMOSOME 17; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOBASAL DEGENERATION; CYTOPLASM; DENTATE GYRUS; ENTORHINAL CORTEX; ENZYME ACTIVATION; ESSENTIAL TREMOR; FEMALE; FRONTOTEMPORAL DEMENTIA WITH PARKINSONISM; GLIA CELL; GUAM PARKINSON DEMENTIA COMPLEX; HIPPOCAMPAL CA1 REGION; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO STUDY; MALE; NEURITE; NEUROFIBRILLARY TANGLE; NEUROPIL THREAD; PAIRED HELICAL FILAMENT; PALLIDOPONTONIGRAL DEGENERATION; PICK PRESENILE DEMENTIA; PRIORITY JOURNAL; PROGRESSIVE NONFLUENT APHASIA; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TANGLE PREDOMINANT DEMENTIA; TAUOPATHY; TEMPORAL CORTEX;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMP-ACTIVATED PROTEIN KINASES; DEMENTIA; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; NEURONS; PARKINSON DISEASE; PHOSPHORYLATION; PICK DISEASE OF THE BRAIN; RETROSPECTIVE STUDIES; TAU PROTEINS; TAUOPATHIES;

EID: 79952135316     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-010-0759-x     Document Type: Article

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