Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis

Molecular and Cellular Biology

Volumn 29, Issue 13, 2009, Pages 3582-3596

  Xie, Zhonglin ^a   Dong, Yunzhou ^a   Zhang, Junhua ^a   Scholz, Roland ^b   Neumann, Dietbert ^b   Zou, Ming Hui ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ALANINE; ASPARTIC ACID; EXPORTIN 1; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEROXYNITRITE; PROTEIN KINASE C ZETA; PROTEIN KINASE LKB1; PROTEIN STRAD; PROTEIN STRADALPHA; SERINE; UNCLASSIFIED DRUG;

ADENOVIRUS; ANGIOGENESIS; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; MUTATION; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; VASCULAR SMOOTH MUSCLE;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; CELL LINE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; HYPOGLYCEMIC AGENTS; KARYOPHERINS; METFORMIN; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; OXIDANTS; PEROXYNITROUS ACID; PHOSPHORYLATION; POINT MUTATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING; SERINE;

EID: 67650083087     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01417-08     Document Type: Article

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