Glucose regulates protein interactions within the yeast SNF1 protein kinase complex

Genes and Development

Volumn 10, Issue 24, 1996, Pages 3105-3115

  Jiang, Rong ^a   Carlson, Marian ^a  

^a Columbia University ^*  (United States)

Author keywords

autoinhibition; glucose signal; S. cerevisiae; SNF1 protein kinase

Indexed keywords

GLUCOSE; PROTEIN KINASE;

ARTICLE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; FUNGAL GENETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; YEAST;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0030468365     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.24.3105     Document Type: Article

References (60)

1. Aguan, K., J. Scott, C.G. See, and N. Sarkar. 1994. Characterization and chromosomal localization of the human homologue of a rat AMP-activated protein kinase-encoding gene: A major regulator of lipid metabolism in mammals. Gene 149: 345-350.
2. Alderson, A., P.A. Sabelli, J.R. Dickinson, D. Cole, M. Richardson, M. Kreis, P.R. Shewry, and N.G. Halford. 1991. Complementation of snf1, a mutation affecting global regulation of carbon metabolism in yeast, by a plant protein kinase cDNA. Proc. Natl Acad. Sci. 88: 8602-8605.
3. Carling, D., K. Aguan, A. Woods, A.J.M. Verhoeven, R.K. Beri, C.H. Brennan, C. Sidebottom, M.D. Davison, and J. Scott. 1994. Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism. J. Biol. Chem. 289: 11442-11448.
4. Celenza, J.L. and M. Carlson. 1986. A yeast gene that is essential for release from glucose repression encodes a protein kinase. Science 233: 1175-1180.
5. _. 1989. Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein. Mol. Cell. Biol. 9: 5034-5044.
6. Celenza, J.L., F.J. Eng, and M. Carlson. 1989. Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: Evidence for physical association of the SNF4 protein with the SNF1 protein kinase. Mol Cell. Biol 9: 5045-5054.
7. Chien, C., P.L. Bartel, R. Sternglanz, and S. Fields. 1991. The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. 88: 9578-9582.
8. Corton, J.M., J.G. Gillespie, and D.G. Hardie. 1994. Role of the AMP-activated protein kinase in the cellular stress response. Curr. Biol. 4: 315-324.
9. Dale, S., W. Wilson, A. Edelman, and D.G. Hardie. 1995. Similar substrate recognition motifs for mammalian AMP-activated protien kinase, higher plant HMG-CoA reductase kinase-A, yeast SNF1, and mammalian calmodulin-dependent protein kinase I. FEBS Lett. 361: 191-195.
10. Denis, C.L., J. Ferguson, and E.T. Young. 1983. mRNA levels for the fermentative alcohol dehydrogenase of Saccharomyces cerevisiae decrease upon growth on a nonfermentable carbon source. J. Biol. Chem. 258: 1165-1171.
11. Dombek, K.M. and E.T. Young. 1993. ADH2 expression is repressed by REG1 independently of mutations that alter the phosphorylation of the yeast transcription factor ADR1. Mol. Cell. Biol. 13: 4391-4399.
12. Durfee, T., K. Becherer, P.-L. Chen, S.-H. Yeh, Y. Yang, A. Kilburn, W.-H. Lee, and S. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes &. Dev. 7: 555-569.
13. Erickson, J.R. and M. Johnston. 1993. Genetic and molecular characterization of GAL83: Its interaction and similarities with other genes involved in glucose repression in Saccharomyces cerevisiae. Genetics 135: 655-664.
14. Estruch, F., M.A. Treitel, X. Yang, and M. Carlson. 1992. N-terminal mutations modulate yeast SNF1 protein kinase function. Genetics 132: 639-650.
15. Fields, S. and O. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature 340: 245-246.
16. Frangioni, J.V. and B.C. Neel. 1993. Solubilization and purification of enzymatically active glutathione S-tranferase (pGEX) fusion proteins. Anal. Biochem. 210: 179-187.
17. Gao, G., J. Widmer, D. Stapleton, T. Teh, T. Cox, B. Kemp, and L. Witters. 1995. Catalytic subunits of the porcine and rat 5′-AMP-activated protein kinase are members of the SNF1 protein kinase family. Biochim. Biophys. Acta 1266: 73-82.
18. Gill, G. and M. Ptashne. 1987. Mutants of GAL4 protein altered in an activation function. Cell 51: 121-126.
19. Goffrini, P., A. Ficarelli, C. Donnini, T. Lodi, P.P. Puglisi, and I. Ferrero. 1996. FOG1 and FOG2 genes, required for the transcriptional activation of glucose-repressible genes of Kluyveromyces lactis, are homologous to GAL83 and SNF1 of Saccharomyces cerevisiae. Curr. Genet. 29: 316-326.
20. Goldberg, J., A.C. Nairn, and J. Kuriyan. 1996. Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I. Cell 84: 875-887.
21. Guo, S. and K.J. Kemphues. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative ser/thr kinase that is asymmetrically distributed. Cell 81: 611-620.
22. Halford, N.G., J. Vicente-Carbajosa, P.A. Sabelli, P.R. Shewry, U. Hannappel, and M. Kreis. 1992. Molecular analyses of a barley multigene family homologous to the yeast protein kinase gene SNF1. Plant J. 2: 791-797.
23. Hanes, S.D. and R. Brent. 1989. DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell 57: 1275-1283.
24. Hanks, S.K. and T. Hunter. 1995. The eucaryotic protein kinase superfamily. In The protein kinase factsbook: Protein-serine kinases (ed. G. Hardie and S. Hanks), pp. 7-47. Academic Press, San Diego, CA.
25. Hardie, D.G. 1992. Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase. Biochim. Biophys. Acta. 1123: 231-238.
26. Hardie, D.G. 1994. Ways of coping with stress. Nature 370: 599-600.
27. Hardie, D.G., D. Carling, and N. Halford. 1994. Role of the Snf1/Rkin1/AMP-activated protein kinase family in the response to environment and nutritional stress. Semin. Cell Biol. 5: 409-416.
28. 2+/S100 regulation of giant protein kinases. Nature 380: 636-639.
29. Jang, J.-C. and J. Sheen. 1994. Sugar sensing in higher plants. Plant Cell 6: 1665-1679.
30. Johnston, M. and M. Carlson. 1992. Regulation of carbon and phosphate utilization. In The molecular and cellular biology of the yeast Saccharomyces: Gene expression (ed. E.W. Jones, J.R. Pringle and J.R. Broach), Vol. 2, pp. 193-281. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
31. Keleher, C.A., M.J. Redd, J. Schultz, M. Carlson, and A.D. Johnson. 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68: 708-719.
32. Kemp, B.E. and R.B. Pearson. 1991. Intrasteric regulation of protein kinases and phosphatases. Biochim. Biophys. Acta 1094: 67-76.
33. Kuchin, S., P. Yeghiayan, and M. Carlson. 1995. Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. Proc. Natl. Acad. Sci. 92: 4006-4010.
34. Legrain, P., M.-C. Dokhelar, and C. Transy. 1994. Detection of protein-protein interactions using different vectors in the two-hybrid system. Nucleic Acids Res. 22: 3241-3242.
35. Le Guen, L., M. Thomas, M. Bianchi, N.G. Halford, and M. Kreis. 1992. Structure and expression of a gene from Arabidopsis thaliana encoding a protein related to SNF1 protein kinase. Gene 120: 249-254.
36. Leung, D., E. Chen, and D. Goeddal. 1989. A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction. Technique 1: 11-15.
37. Ma, J. and M. Ptashne. 1987. A new class of yeast transcriptional activators. Cell 51: 113-119.
38. Mitchelhill, K.I., D. Stapleton, G. Gao, C. House, B. Michell, F. Katsis, L.A. Witters, and B.E. Kemp. 1994. Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase. J. Biol. Chem. 269: 2361-2364.
39. Muranaka, T., H. Banno, and Y. Machida. 1994. Characterization of tobacco protein kinase NPK5, a homolog of Saccharomyces cerevisiae SNF1 that constitutively activates expression of the glucose-repressible SUC2 gene for a secreted invertase of S. cerevisiae. Mol. Cell Biol 14: 2958-2965.
40. Neigeborn, L. and M. Carlson. 1987. Mutations causing constitutive invertase synthesis in yeast: Genetic interactions with snf mutations. Genetics 115: 247-253.
41. + gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. Cell 57: 997-1007.
42. Rose, M.D., F. Winston, and P. Hieter. 1990. Methods in yeast genetics: A laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
43. Ruden, D.M., J. Ma, Y. Li, K. Wood, and M. Ptashne. 1991. Generating yeast transcriptional activators containing no yeast protein sequences. Nature 350: 250-252.
44. Ruiz, J., F. Conlon, and E. Robertson. 1994. Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. Mech. Dev. 48: 153-164.
45. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular cloning: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
46. Schuller, H.-J. and K.-D. Entian. 1987. Isolation and expression analysis of two yeast regulatory genes involved in the derepression of glucose-repressible enzymes. Mol. Gen. Genet. 209: 366-373.
47. _. 1988. Molecular characterization of yeast regulatory gene CAT3 necessary for glucose derepression and nuclear localization of its product. Gene 67: 247-257.
48. 2+/calmodulin-dependent protein kinases. Curr. Biol. 5: 247-253.
49. Schultz, J. and M. Carlson. 1987. Molecular analysis of SSN6. a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae. Mol. Cell. Biol 7: 3637-3645.
50. Simon, M., M. Binder, G. Adam, A. Hartig, and H. Ruis. 1992. Control of peroxisome proliferation in Saccharomyces cerevisiae by ADR1, SNF1 (CAT1, CCR1) and SNF4 (CAT3). Yeast 8: 303-309.
51. Stapleton, D., G. Gao, B. Michell, J. Widmer, K. Mitchehill, T. Teh, C. House, L. Witters, and B. Kemp. 1994. Mammalian 5′-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. J. Biol. Chem. 269: 29343-29346.
52. Thompson-Jaeger, S., J. Francois, J.P. Gaughran, and K. Tatchell. 1991. Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway. Genetics 129: 697-706.
53. Tu, J. and M. Carlson. 1994. The GLC7 type 1 protein phosphatase is required for glucose repression in Saccharomyces cerevisiae. Mol. Cell. Biol. 14: 6789-6796.
54. _. 1995. REG1 binds to protein phosphatasc type 1 and regulates glucose repression in Saccharomyces cerevisiae. EMBO J. 14: 5939-5946.
55. Vojtek, A.B., S.M. Hollenberg, and J.A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205-214.
56. Woods, A., M.R. Munday, J. Scott, X. Yang, M. Carlson, and D. Carling. 1994. Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. J. Biol. Chem. 269: 19509-19516.
57. Woods, A., P.C. Cheung, F.C. Smith, M.D. Davison, J. Scott, R.K. Beri, and D. Carling. 1996. Characterization of AMP-activated protein kinase β and γ subunits. J. Biol. Chem. 271: 10282-10290.
58. Yang, X., E.J.A. Hubbard, and M. Carlson. 1992. A protein kinase substrate identified by the two-hybrid system. Science 257: 680-682.
59. Yang, X., R. Jiang, and M. Carlson. 1994. A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex. EMBO J. 13: 5878-5886.
60. Zhou, Y., X. Zhang, and R.H. Ebright. 1991. Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase. Nucleic Acids Res. 19: 6052.