-
1
-
-
0033610891
-
Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta
-
Anderson K.A., Means R.L., Huang Q.H., Kemp B.E., Goldstein E.G., Selbert M.A., Edelman A.M., Fremeau R.T., and Means A.R. Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta. J. Biol. Chem. 273 (1998) 31880-31889
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31880-31889
-
-
Anderson, K.A.1
Means, R.L.2
Huang, Q.H.3
Kemp, B.E.4
Goldstein, E.G.5
Selbert, M.A.6
Edelman, A.M.7
Fremeau, R.T.8
Means, A.R.9
-
2
-
-
1842582870
-
AMP-activated protein kinase plays a role in the control of food intake
-
Andersson U., Filipsson K., Abbott C.R., Woods A., Smith K., Bloom S.R., Carling D., and Small C.J. AMP-activated protein kinase plays a role in the control of food intake. J. Biol. Chem. 279 (2004) 12005-12008
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12005-12008
-
-
Andersson, U.1
Filipsson, K.2
Abbott, C.R.3
Woods, A.4
Smith, K.5
Bloom, S.R.6
Carling, D.7
Small, C.J.8
-
3
-
-
0036157858
-
Ghrelin and leptin pulse discharge in fed and fasted rats
-
Bagnasco M., Kalra P.S., and Kalra S.P. Ghrelin and leptin pulse discharge in fed and fasted rats. Endocrinology 143 (2002) 726-729
-
(2002)
Endocrinology
, vol.143
, pp. 726-729
-
-
Bagnasco, M.1
Kalra, P.S.2
Kalra, S.P.3
-
4
-
-
0037244070
-
Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations
-
Banks W.A. Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations. Curr. Pharm. Des. 9 (2003) 801-809
-
(2003)
Curr. Pharm. Des.
, vol.9
, pp. 801-809
-
-
Banks, W.A.1
-
5
-
-
0035851843
-
Hypothalamic and vagal neuropeptide circuitries regulating food intake
-
Broberger C., and Hokfelt T. Hypothalamic and vagal neuropeptide circuitries regulating food intake. Physiol. Behav. 74 (2001) 669-682
-
(2001)
Physiol. Behav.
, vol.74
, pp. 669-682
-
-
Broberger, C.1
Hokfelt, T.2
-
6
-
-
0041319433
-
Effect of exercise intensity on skeletal muscle AMPK signaling in humans
-
Chen Z.P., Stephens T.J., Murthy S., Canny B.J., Hargreaves M., Witters L.A., Kemp B.E., and McConell G.K. Effect of exercise intensity on skeletal muscle AMPK signaling in humans. Diabetes 52 (2003) 2205-2212
-
(2003)
Diabetes
, vol.52
, pp. 2205-2212
-
-
Chen, Z.P.1
Stephens, T.J.2
Murthy, S.3
Canny, B.J.4
Hargreaves, M.5
Witters, L.A.6
Kemp, B.E.7
McConell, G.K.8
-
7
-
-
0021248888
-
Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
-
Clark J.T., Kalra P.S., Crowley W.R., and Kalra S.P. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115 (1984) 427-429
-
(1984)
Endocrinology
, vol.115
, pp. 427-429
-
-
Clark, J.T.1
Kalra, P.S.2
Crowley, W.R.3
Kalra, S.P.4
-
8
-
-
0032567252
-
Functional domains of the alpha1 catalytic subunit of the AMP-activated protein kinase
-
Crute B.E., Seefeld K., Gamble J., Kemp B.E., and Witters L.A. Functional domains of the alpha1 catalytic subunit of the AMP-activated protein kinase. J. Biol. Chem. 273 (1998) 35347-35354
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 35347-35354
-
-
Crute, B.E.1
Seefeld, K.2
Gamble, J.3
Kemp, B.E.4
Witters, L.A.5
-
9
-
-
0037162116
-
Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery
-
Cummings D.E., Weigle D.S., Frayo R.S., Breen P.A., Ma M.K., Dellinger E.P., and Purnell J.Q. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N. Engl. J. Med. 346 (2002) 1623-1630
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1623-1630
-
-
Cummings, D.E.1
Weigle, D.S.2
Frayo, R.S.3
Breen, P.A.4
Ma, M.K.5
Dellinger, E.P.6
Purnell, J.Q.7
-
11
-
-
0029944966
-
Regulation of 5′-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits
-
Dyck J.R., Gao G., Widmer J., Stapleton D., Fernandez C.S., Kemp B.E., and Witters L.A. Regulation of 5′-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits. J. Biol. Chem. 271 (1996) 17798-17803
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17798-17803
-
-
Dyck, J.R.1
Gao, G.2
Widmer, J.3
Stapleton, D.4
Fernandez, C.S.5
Kemp, B.E.6
Witters, L.A.7
-
12
-
-
27744436291
-
Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis
-
Elmquist J.K., Coppari R., Balthasar N., Ichinose M., and Lowell B.B. Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis. J. Comp. Neurol. 493 (2005) 63-71
-
(2005)
J. Comp. Neurol.
, vol.493
, pp. 63-71
-
-
Elmquist, J.K.1
Coppari, R.2
Balthasar, N.3
Ichinose, M.4
Lowell, B.B.5
-
13
-
-
0029946644
-
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
-
Erickson J.C., Clegg K.E., and Palmiter R.D. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381 (1996) 415-421
-
(1996)
Nature
, vol.381
, pp. 415-421
-
-
Erickson, J.C.1
Clegg, K.E.2
Palmiter, R.D.3
-
14
-
-
35548949948
-
Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
-
Esler W.P., Rudolph J., Claus T.H., Tang W., Barucci N., Brown S.E., Bullock W., Daly M., Decarr L., Li Y., et al. Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss. Endocrinology 148 (2007) 5175-5185
-
(2007)
Endocrinology
, vol.148
, pp. 5175-5185
-
-
Esler, W.P.1
Rudolph, J.2
Claus, T.H.3
Tang, W.4
Barucci, N.5
Brown, S.E.6
Bullock, W.7
Daly, M.8
Decarr, L.9
Li, Y.10
-
15
-
-
0842324779
-
Obesity wars: molecular progress confronts an expanding epidemic
-
Flier J.S. Obesity wars: molecular progress confronts an expanding epidemic. Cell 116 (2004) 337-350
-
(2004)
Cell
, vol.116
, pp. 337-350
-
-
Flier, J.S.1
-
16
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman J.M., and Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 395 (1998) 763-770
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
17
-
-
0033391143
-
Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice
-
Gainetdinov R.R., Bohn L.M., Walker J.K., Laporte S.A., Macrae A.D., Caron M.G., Lefkowitz R.J., and Premont R.T. Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice. Neuron 24 (1999) 1029-1036
-
(1999)
Neuron
, vol.24
, pp. 1029-1036
-
-
Gainetdinov, R.R.1
Bohn, L.M.2
Walker, J.K.3
Laporte, S.A.4
Macrae, A.D.5
Caron, M.G.6
Lefkowitz, R.J.7
Premont, R.T.8
-
19
-
-
27344433932
-
Agouti-related peptide-expressing neurons are mandatory for feeding
-
Gropp E., Shanabrough M., Borok E., Xu A.W., Janoschek R., Buch T., Plum L., Balthasar N., Hampel B., Waisman A., et al. Agouti-related peptide-expressing neurons are mandatory for feeding. Nat. Neurosci. 8 (2005) 1289-1291
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1289-1291
-
-
Gropp, E.1
Shanabrough, M.2
Borok, E.3
Xu, A.W.4
Janoschek, R.5
Buch, T.6
Plum, L.7
Balthasar, N.8
Hampel, B.9
Waisman, A.10
-
20
-
-
0038199737
-
Management of cellular energy by the AMP-activated protein kinase system
-
Hardie D.G., Scott J.W., Pan D.A., and Hudson E.R. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett. 546 (2003) 113-120
-
(2003)
FEBS Lett.
, vol.546
, pp. 113-120
-
-
Hardie, D.G.1
Scott, J.W.2
Pan, D.A.3
Hudson, E.R.4
-
21
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley S.A., Pan D.A., Mustard K.J., Ross L., Bain J., Edelman A.M., Frenguelli B.G., and Hardie D.G. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab. 2 (2005) 9-19
-
(2005)
Cell Metab.
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
22
-
-
0032747280
-
Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial
-
Heymsfield S.B., Greenberg A.S., Fujioka K., Dixon R.M., Kushner R., Hunt T., Lubina J.A., Patane J., Self B., Hunt P., and McCamish M. Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. JAMA 282 (1999) 1568-1575
-
(1999)
JAMA
, vol.282
, pp. 1568-1575
-
-
Heymsfield, S.B.1
Greenberg, A.S.2
Fujioka, K.3
Dixon, R.M.4
Kushner, R.5
Hunt, T.6
Lubina, J.A.7
Patane, J.8
Self, B.9
Hunt, P.10
McCamish, M.11
-
23
-
-
24344479915
-
Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling
-
Holst B., Brandt E., Bach A., Heding A., and Schwartz T.W. Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling. Mol. Endocrinol. 19 (2005) 2400-2411
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 2400-2411
-
-
Holst, B.1
Brandt, E.2
Bach, A.3
Heding, A.4
Schwartz, T.W.5
-
24
-
-
28844433549
-
A role for hypothalamic malonyl-CoA in the control of food intake
-
Hu Z., Dai Y., Prentki M., Chohnan S., and Lane M.D. A role for hypothalamic malonyl-CoA in the control of food intake. J. Biol. Chem. 280 (2005) 39681-39683
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39681-39683
-
-
Hu, Z.1
Dai, Y.2
Prentki, M.3
Chohnan, S.4
Lane, M.D.5
-
25
-
-
23844471263
-
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases
-
Hurley R.L., Anderson K.A., Franzone J.M., Kemp B.E., Means A.R., and Witters L.A. The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J. Biol. Chem. 280 (2005) 29060-29066
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29060-29066
-
-
Hurley, R.L.1
Anderson, K.A.2
Franzone, J.M.3
Kemp, B.E.4
Means, A.R.5
Witters, L.A.6
-
26
-
-
33845972272
-
Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP
-
Hurley R.L., Barre L.K., Wood S.D., Anderson K.A., Kemp B.E., Means A.R., and Witters L.A. Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP. J. Biol. Chem. 281 (2006) 36662-36672
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36662-36672
-
-
Hurley, R.L.1
Barre, L.K.2
Wood, S.D.3
Anderson, K.A.4
Kemp, B.E.5
Means, A.R.6
Witters, L.A.7
-
27
-
-
4344595580
-
NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy
-
Kalra S.P., and Kalra P.S. NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy. Neuropeptides 38 (2004) 201-211
-
(2004)
Neuropeptides
, vol.38
, pp. 201-211
-
-
Kalra, S.P.1
Kalra, P.S.2
-
28
-
-
0037382853
-
Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin
-
Kohno D., Gao H.Z., Muroya S., Kikuyama S., and Yada T. Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin. Diabetes 52 (2003) 948-956
-
(2003)
Diabetes
, vol.52
, pp. 948-956
-
-
Kohno, D.1
Gao, H.Z.2
Muroya, S.3
Kikuyama, S.4
Yada, T.5
-
29
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
30
-
-
21644453934
-
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
-
Kola B., Hubina E., Tucci S.A., Kirkham T.C., Garcia E.A., Mitchell S.E., Williams L.M., Hawley S.A., Hardie D.G., Grossman A.B., and Korbonits M. Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J. Biol. Chem. 280 (2005) 25196-25201
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25196-25201
-
-
Kola, B.1
Hubina, E.2
Tucci, S.A.3
Kirkham, T.C.4
Garcia, E.A.5
Mitchell, S.E.6
Williams, L.M.7
Hawley, S.A.8
Hardie, D.G.9
Grossman, A.B.10
Korbonits, M.11
-
31
-
-
0032417697
-
Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice
-
Kushi A., Sasai H., Koizumi H., Takeda N., Yokoyama M., and Nakamura M. Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice. Proc. Natl. Acad. Sci. USA 95 (1998) 15659-15664
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15659-15664
-
-
Kushi, A.1
Sasai, H.2
Koizumi, H.3
Takeda, N.4
Yokoyama, M.5
Nakamura, M.6
-
32
-
-
0035836760
-
Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity
-
Lambert P.D., Anderson K.D., Sleeman M.W., Wong V., Tan J., Hijarunguru A., Corcoran T.L., Murray J.D., Thabet K.E., Yancopoulos G.D., and Wiegand S.J. Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity. Proc. Natl. Acad. Sci. USA 98 (2001) 4652-4657
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4652-4657
-
-
Lambert, P.D.1
Anderson, K.D.2
Sleeman, M.W.3
Wong, V.4
Tan, J.5
Hijarunguru, A.6
Corcoran, T.L.7
Murray, J.D.8
Thabet, K.E.9
Yancopoulos, G.D.10
Wiegand, S.J.11
-
33
-
-
27344431720
-
NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
-
Luquet S., Perez F.A., Hnasko T.S., and Palmiter R.D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 310 (2005) 683-685
-
(2005)
Science
, vol.310
, pp. 683-685
-
-
Luquet, S.1
Perez, F.A.2
Hnasko, T.S.3
Palmiter, R.D.4
-
34
-
-
0038748202
-
Characterization of neuropeptide Y (NPY) Y5 receptor-mediated obesity in mice: chronic intracerebroventricular infusion of D-Trp(34)NPY
-
Mashiko S., Ishihara A., Iwaasa H., Sano H., Oda Z., Ito J., Yumoto M., Okawa M., Suzuki J., Fukuroda T., et al. Characterization of neuropeptide Y (NPY) Y5 receptor-mediated obesity in mice: chronic intracerebroventricular infusion of D-Trp(34)NPY. Endocrinology 144 (2003) 1793-1801
-
(2003)
Endocrinology
, vol.144
, pp. 1793-1801
-
-
Mashiko, S.1
Ishihara, A.2
Iwaasa, H.3
Sano, H.4
Oda, Z.5
Ito, J.6
Yumoto, M.7
Okawa, M.8
Suzuki, J.9
Fukuroda, T.10
-
35
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y., Alquier T., Furukawa N., Kim Y.B., Lee A., Xue B., Mu J., Foufelle F., Ferre P., Birnbaum M.J., et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428 (2004) 569-574
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
-
36
-
-
3142723983
-
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
-
Mori H., Hanada R., Hanada T., Aki D., Mashima R., Nishinakamura H., Torisu T., Chien K.R., Yasukawa H., and Yoshimura A. Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nat. Med. 10 (2004) 739-743
-
(2004)
Nat. Med.
, vol.10
, pp. 739-743
-
-
Mori, H.1
Hanada, R.2
Hanada, T.3
Aki, D.4
Mashima, R.5
Nishinakamura, H.6
Torisu, T.7
Chien, K.R.8
Yasukawa, H.9
Yoshimura, A.10
-
37
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton G.J., Cummings D.E., Baskin D.G., Barsh G.S., and Schwartz M.W. Central nervous system control of food intake and body weight. Nature 443 (2006) 289-295
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
38
-
-
17844401180
-
Molecular and anatomical determinants of central leptin resistance
-
Munzberg H., and Myers Jr. M.G. Molecular and anatomical determinants of central leptin resistance. Nat. Neurosci. 8 (2005) 566-570
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 566-570
-
-
Munzberg, H.1
Myers Jr., M.G.2
-
39
-
-
0043071497
-
Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli
-
Neumann D., Woods A., Carling D., Wallimann T., and Schlattner U. Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli. Protein Expr. Purif. 30 (2003) 230-237
-
(2003)
Protein Expr. Purif.
, vol.30
, pp. 230-237
-
-
Neumann, D.1
Woods, A.2
Carling, D.3
Wallimann, T.4
Schlattner, U.5
-
40
-
-
0031779479
-
Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor
-
Pedrazzini T., Seydoux J., Kunstner P., Aubert J.F., Grouzmann E., Beermann F., and Brunner H.R. Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor. Nat. Med. 4 (1998) 722-726
-
(1998)
Nat. Med.
, vol.4
, pp. 722-726
-
-
Pedrazzini, T.1
Seydoux, J.2
Kunstner, P.3
Aubert, J.F.4
Grouzmann, E.5
Beermann, F.6
Brunner, H.R.7
-
41
-
-
1842584230
-
Fat, carbohydrate, and calories in the development of diabetes and obesity in the C57BL/6J mouse
-
Petro A.E., Cotter J., Cooper D.A., Peters J.C., Surwit S.J., and Surwit R.S. Fat, carbohydrate, and calories in the development of diabetes and obesity in the C57BL/6J mouse. Metabolism 53 (2004) 454-457
-
(2004)
Metabolism
, vol.53
, pp. 454-457
-
-
Petro, A.E.1
Cotter, J.2
Cooper, D.A.3
Peters, J.C.4
Surwit, S.J.5
Surwit, R.S.6
-
42
-
-
20044370885
-
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
-
Sakamoto K., McCarthy A., Smith D., Green K.A., Grahame Hardie D., Ashworth A., and Alessi D.R. Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. EMBO J. 24 (2005) 1810-1820
-
(2005)
EMBO J.
, vol.24
, pp. 1810-1820
-
-
Sakamoto, K.1
McCarthy, A.2
Smith, D.3
Green, K.A.4
Grahame Hardie, D.5
Ashworth, A.6
Alessi, D.R.7
-
43
-
-
0037502842
-
NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting
-
Segal-Lieberman G., Trombly D.J., Juthani V., Wang X., and Maratos-Flier E. NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting. Am. J. Physiol. Endocrinol. Metab. 284 (2003) E1131-E1139
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.284
-
-
Segal-Lieberman, G.1
Trombly, D.J.2
Juthani, V.3
Wang, X.4
Maratos-Flier, E.5
-
44
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw R.J., Kosmatka M., Bardeesy N., Hurley R.L., Witters L.A., DePinho R.A., and Cantley L.C. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. USA 101 (2004) 3329-3335
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
DePinho, R.A.6
Cantley, L.C.7
-
45
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw R.J., Lamia K.A., Vasquez D., Koo S.H., Bardeesy N., Depinho R.A., Montminy M., and Cantley L.C. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310 (2005) 1642-1646
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.H.4
Bardeesy, N.5
Depinho, R.A.6
Montminy, M.7
Cantley, L.C.8
-
46
-
-
33746037555
-
Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
-
Steinberg G.R., Watt M.J., Fam B.C., Proietto J., Andrikopoulos S., Allen A.M., Febbraio M.A., and Kemp B.E. Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. Endocrinology 147 (2006) 3906-3914
-
(2006)
Endocrinology
, vol.147
, pp. 3906-3914
-
-
Steinberg, G.R.1
Watt, M.J.2
Fam, B.C.3
Proietto, J.4
Andrikopoulos, S.5
Allen, A.M.6
Febbraio, M.A.7
Kemp, B.E.8
-
47
-
-
1842480284
-
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
-
Sun Y., Wang P., Zheng H., and Smith R.G. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc. Natl. Acad. Sci. USA 101 (2004) 4679-4684
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4679-4684
-
-
Sun, Y.1
Wang, P.2
Zheng, H.3
Smith, R.G.4
-
48
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit R.S., Kuhn C.M., Cochrane C., McCubbin J.A., and Feinglos M.N. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37 (1988) 1163-1167
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
49
-
-
0032589260
-
Substrate recognition by Ca2+/Calmodulin-dependent protein kinase kinase. Role of the arg-pro-rich insert domain
-
Tokumitsu H., Takahashi N., Eto K., Yano S., Soderling T.R., and Muramatsu M. Substrate recognition by Ca2+/Calmodulin-dependent protein kinase kinase. Role of the arg-pro-rich insert domain. J. Biol. Chem. 274 (1999) 15803-15810
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15803-15810
-
-
Tokumitsu, H.1
Takahashi, N.2
Eto, K.3
Yano, S.4
Soderling, T.R.5
Muramatsu, M.6
-
50
-
-
0037013222
-
STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase
-
Tokumitsu H., Inuzuka H., Ishikawa Y., Ikeda M., Saji I., and Kobayashi R. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J. Biol. Chem. 277 (2002) 15813-15818
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15813-15818
-
-
Tokumitsu, H.1
Inuzuka, H.2
Ishikawa, Y.3
Ikeda, M.4
Saji, I.5
Kobayashi, R.6
-
51
-
-
30944448596
-
Chutes and Ladders: the search for protein kinases that act on AMPK
-
Witters L.A., Kemp B.E., and Means A.R. Chutes and Ladders: the search for protein kinases that act on AMPK. Trends Biochem. Sci. 31 (2006) 13-16
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 13-16
-
-
Witters, L.A.1
Kemp, B.E.2
Means, A.R.3
-
52
-
-
23044437445
-
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
Woods A., Dickerson K., Heath R., Hong S.P., Momcilovic M., Johnstone S.R., Carlson M., and Carling D. Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2 (2005) 21-33
-
(2005)
Cell Metab.
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
53
-
-
23944444300
-
Health consequences of obesity in the elderly: a review of four unresolved questions
-
Zamboni M., Mazzali G., Zoico E., Harris T.B., Meigs J.B., Di Francesco V., Fantin F., Bissoli L., and Bosello O. Health consequences of obesity in the elderly: a review of four unresolved questions. Int. J. Obes. (Lond.) 29 (2005) 1011-1029
-
(2005)
Int. J. Obes. (Lond.)
, vol.29
, pp. 1011-1029
-
-
Zamboni, M.1
Mazzali, G.2
Zoico, E.3
Harris, T.B.4
Meigs, J.B.5
Di Francesco, V.6
Fantin, F.7
Bissoli, L.8
Bosello, O.9
|