Metformin decreases IGF1-induced cell proliferation and protein synthesis through AMP-activated protein kinase in cultured bovine granulosa cells

Reproduction

Volumn 139, Issue 2, 2010, Pages 409-418

  Tosca, Lucie ^a   Ramé, Christelle ^a   Chabrolle, Christine ^a   Tesseraud, Sophie ^b   Dupont, Joëlle ^a  

^a UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

^b STATION DE RECHERCHES AVICOLES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; CYCLIN D2; CYCLIN E; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; P70S6 KINASE; P90RSK KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN P21; PROTEIN P27; S6 KINASE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; COW; DRUG EFFECT; DRUG MECHANISM; EMBRYO; ENZYME PHOSPHORYLATION; FEMALE; GRANULOSA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CATTLE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D2; CYCLIN E; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; FEMALE; FERTILITY AGENTS, FEMALE; GRANULOSA CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; METFORMIN; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SIGNAL TRANSDUCTION; TRANSFECTION;

ADENOVIRIDAE; BOVINAE;

EID: 75149186480     PISSN: 14701626     EISSN: 17417899     Source Type: Journal    
DOI: 10.1530/REP-09-0351     Document Type: Article

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