AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure

Biochemical Journal

Volumn 434, Issue 3, 2011, Pages 503-512

  Thornton, Claire ^a   Bright, Nicola J ^a   Sastre, Magdalena ^b   Muckett, Phillip J ^a   Carling, David ^a  

^a MRC CLINICAL SCIENCES CENTRE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Alzheimer's disease; AMP activated protein kinase (AMPK); Amyloid peptide; Microtubule associated protein; N methyl D aspartate (NMDA); Tau

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; COMPLEMENTARY DNA; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MEMANTINE; MICROTUBULE ASSOCIATED PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHORUS 32; RECOMBINANT PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ASSAY; MASS SPECTROMETRY; MICROTUBULE; NERVE CELL; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; AMYLOID BETA-PEPTIDES; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CATALYTIC DOMAIN; CELLS, CULTURED; CEREBRAL CORTEX; ENZYME ACTIVATION; MEMANTINE; MICE; MICROTUBULES; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, N-METHYL-D-ASPARTATE; TAU PROTEINS;

EID: 79952135798     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101485     Document Type: Article

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