Proteasome activation delays aging in vitro and in vivo

Free Radical Biology and Medicine

Volumn 71, Issue , 2014, Pages 303-320

  Chondrogianni, Niki ^a   Sakellari, Marianthi ^a,b   Lefaki, Maria ^a   Papaevgeniou, Nikoletta ^a   Gonos, Efstathios S ^a,b  

^a INSTITUTE OF BIOLOGY   (Greece)

^b ÖREBRO UNIVERSITY   (Sweden)

Author keywords

Aging; Free radicals; Longevity regulation; Proteasome activation; Senescence; Ubiquitin proteasome system

Indexed keywords

19S REGULATORY PARTICLE; ENZYME; PROTEASOME; UNCLASSIFIED DRUG; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; ANTIOXIDANT; FREE RADICAL; NUCLEAR PROTEIN; PA700 PROTEASOME ACTIVATOR; PROTEASOME ACTIVATOR 200 KDA, HUMAN;

AGING; AUTOPHAGY; DOWN REGULATION; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME STRUCTURE; GERIATRIC DISORDER; HUMAN; IN VITRO STUDY; LONGEVITY; LYSOSOME; MUS MUSCULUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; RATTUS NORVEGICUS; REVIEW; SACCHAROMYCES CEREVISIAE; SYSTEMATIC REVIEW; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CAENORHABDITIS ELEGANS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; PROTEIN DEGRADATION; RAT;

AGING; ANIMALS; ANTIOXIDANTS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; FREE RADICALS; HUMANS; LONGEVITY; MICE; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; RATS; SACCHAROMYCES CEREVISIAE;

EID: 84898834965     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.03.031     Document Type: Review

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