Postnatal proteasome inhibition induces neurodegeneration and cognitive deficiencies in adult mice: A new model of neurodevelopment syndrome

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Romero Granados, Rocío ^a,b   Fontán Lozano, Ángela ^a,b   Aguilar Montilla, Francisco Javier ^a   Carrión, Ángel Manuel ^a  

^a UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^b CABIMER Andalusian Center for Molecular Biology and Regenerative Medicine CSIC University of Seville UPO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELL MARKER; LACTACYSTIN; PROTEASOME; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; BIOLOGICAL MARKER; DNA; ENZYME INHIBITOR; LEUPEPTIN; UBIQUITINATED PROTEIN;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BALANCE DISORDER; BEHAVIOR DISORDER; BRAIN STEM; CELL LOSS; COGNITIVE DEFECT; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA METABOLISM; DNA OXIDATION; ENZYME ACTIVITY; ENZYME DEFECT; ENZYME INHIBITION; FEMALE; HIPPOCAMPUS; MALE; MEMORY DISORDER; MENTAL TASK; MORPHOLOGY; MOTOR DYSFUNCTION; MOUSE; NERVE CELL; NERVE DEGENERATION; NEURODEVELOPMENT SYNDROME; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; ANIMAL; ATAXIA; BRAIN; DEPRESSION; DISEASE MODEL; DOPAMINERGIC NERVE CELL; DRUG ANTAGONISM; DRUG EFFECT; EXPLORATORY BEHAVIOR; GROWTH, DEVELOPMENT AND AGING; MEMORY; METABOLISM; MITOCHONDRION; MOTOR ACTIVITY; NERVOUS SYSTEM; OXIDATION REDUCTION REACTION; PATHOLOGY; PATHOPHYSIOLOGY;

AMYGDALA; ANIMALS; ANIMALS, NEWBORN; ATAXIA; BIOLOGICAL MARKERS; BRAIN; COGNITION DISORDERS; DEPRESSION; DISEASE MODELS, ANIMAL; DNA; DOPAMINERGIC NEURONS; ENZYME INHIBITORS; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; LEUPEPTINS; MEMORY; MICE; MITOCHONDRIA; MOTOR ACTIVITY; NERVE DEGENERATION; NERVOUS SYSTEM; OXIDATION-REDUCTION; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITINATED PROTEINS;

EID: 83155164601     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028927     Document Type: Article

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