Synthesis and proteasome inhibition of lithocholic acid derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 7, 2011, Pages 1926-1928

  Dang, Zhao ^a   Lin, Andrew ^a   Ho, Phong ^a   Soroka, Dominique ^a   Lee, Kuo Hsiung ^b,c   Huang, Li ^a   Chen, Chin Ho ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b University of North Carolina   (United States)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Lithocholic acid; Proteasome; Proteasome inhibitor

Indexed keywords

BORTEZOMIB; CHYMOTRYPSIN; LACTACYSTIN; LITHOCHOLIC ACID; LITHOCHOLIC ACID DERIVATIVE; PROTEASOME; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME KINETICS; ESTERIFICATION; HUMAN; IC 50; MOLECULAR SIZE;

HELA CELLS; HUMANS; KINETICS; LITHOCHOLIC ACID; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 79952485141     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.02.041     Document Type: Article

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