Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

Autophagy

Volumn 9, Issue 7, 2013, Pages 973-984

  Kaarniranta, Kai ^a,b   Sinha, Debasish ^c   Blasiak, Janusz ^d   Kauppinen, Anu ^a   Veréb, Zoltán ^e   Salminen, Antero ^a,b   Boulton, Michael E ^f   Petrovski, Goran ^e  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d UNIVERSITY OF LODZ   (Poland)

^e UNIVERSITY OF DEBRECEN   (Hungary)

^f UNIVERSITY OF FLORIDA   (United States)

Author keywords

AMD; Autophagy; Heterophagy; Inflammasome; Lysosome; Oxidative stress; Phagocytosis; Proteasome; RPE

Indexed keywords

4 HYDROXYNONENAL; ADVANCED GLYCATION END PRODUCT; ALPHA CRYSTALLIN; LIPOFUSCIN; LYSOSOME ENZYME; MALONALDEHYDE; MICROTUBULE ASSOCIATED PROTEIN 1; MITOCHONDRIAL DNA; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE;

ACTIN FILAMENT; ANGIOGENESIS; AUTOPHAGOSOME; AUTOPHAGY; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; DISEASE COURSE; DNA DAMAGE; ENDOCYTOSIS; FENTON REACTION; HETEROPHAGY; HUMAN; INTERNALIZATION; LIPID PEROXIDATION; LYSOSOME; MACROAUTOPHAGY; MICROAUTOPHAGY; MICROTUBULE; MICROVILLUS; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PHAGOSOME; PHOTORECEPTOR CELL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; RETINA DETACHMENT; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; SIGNAL TRANSDUCTION; SPONTANEOUS MUTATION; VISION;

AMD; AUTOPHAGY; HETEROPHAGY; INFLAMMASOME; LYSOSOME; OXIDATIVE STRESS; PHAGOCYTOSIS; PROTEASOME; RPE;

AUTOPHAGY; HUMANS; LYSOSOMES; MACULAR DEGENERATION; PHAGOSOMES; PROTEASOME ENDOPEPTIDASE COMPLEX; RETINAL PIGMENT EPITHELIUM;

EID: 84880797112     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.24546     Document Type: Review

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