Proteasomal function is impaired in substantia nigra in Parkinson's disease

Neuroscience Letters

Volumn 297, Issue 3, 2001, Pages 191-194

  McNaught, Kevin St P ^a   Jenner, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Synuclein; Lewy body inclusion; Parkinson's disease; Proteasome; Ubiquitin; Ubiquitin carboxy terminal hydrolase L1

Indexed keywords

ALPHA SYNUCLEIN; CHYMOTRYPSIN; DOPA; PROTEASOME; TRYPSIN; UBIQUITIN;

ADULT; AGED; ARTICLE; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN TISSUE; HYDROLYSIS; LEWY BODY; MALE; NERVE CELL DEGENERATION; NIGRONEOSTRIATAL SYSTEM; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SUBSTANTIA NIGRA;

ACETYLCYSTEINE; AGED; CYSTEINE ENDOPEPTIDASES; DIHYDROXYPHENYLALANINE; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; HUMANS; HYDROLYSIS; LEVODOPA; LEWY BODIES; MALE; MULTIENZYME COMPLEXES; PARKINSON DISEASE; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBSTANTIA NIGRA; UBIQUITINS;

EID: 0035910634     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01701-8     Document Type: Article

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