-
1
-
-
0037763721
-
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
-
Nguyen T., Sherratt P.J., Pickett C.B. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu. Rev. Pharmacol. Toxicol. 43:2003;233-260
-
(2003)
Annu. Rev. Pharmacol. Toxicol.
, vol.43
, pp. 233-260
-
-
Nguyen, T.1
Sherratt, P.J.2
Pickett, C.B.3
-
3
-
-
0032542213
-
Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes
-
Venugopal R., Jaiswal A.K. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene. 17:1998;3145-3156
-
(1998)
Oncogene
, vol.17
, pp. 3145-3156
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
4
-
-
0033584867
-
Regulation of γ-glutamylcysteine synthetase regulatory subunit gene expression by the transcription factor Nrf2
-
Wild A.C., Moinova H.R., Mulcahy R.T. Regulation of γ- glutamylcysteine synthetase regulatory subunit gene expression by the transcription factor Nrf2. J. Biol. Chem. 274:1999;33627-33636
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33627-33636
-
-
Wild, A.C.1
Moinova, H.R.2
Mulcahy, R.T.3
-
5
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxigenase-1 gene
-
Alam J., Stewart D., Touchard C., Boinapally S., Choi A.M.K., Cook J.L. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxigenase-1 gene. J. Biol. Chem. 274:1999;26071-26078
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
Boinapally, S.4
Choi, A.M.K.5
Cook, J.L.6
-
6
-
-
0034685897
-
Transcriptional regulation of the antioxidant response element: Activation by Nrf2 and repression by MafK
-
Nguyen T., Huang H.C., Pickett C.B. Transcriptional regulation of the antioxidant response element: activation by Nrf2 and repression by MafK. J. Biol. Chem. 275:2000;15466-15473
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15466-15473
-
-
Nguyen, T.1
Huang, H.C.2
Pickett, C.B.3
-
7
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., Oyake T., Hayashi N., Satoh K., Hatayama I., Yamamoto M., Nabeshima Y.I. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236:1997;313-322
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.I.12
-
8
-
-
0035870298
-
The cap 'n' collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes
-
McMahon M., Itoh K., Yamamoto M., Chanas S.A., Henderson C.J., McLellan L.I., Wolf C.R., Cavin C., Hayes J.D. The cap 'n' collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res. 61:2001;3299-3307
-
(2001)
Cancer Res.
, vol.61
, pp. 3299-3307
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Chanas, S.A.4
Henderson, C.J.5
McLellan, L.I.6
Wolf, C.R.7
Cavin, C.8
Hayes, J.D.9
-
9
-
-
0037101768
-
Loss of Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
-
Chanas S.A., Jiang Q., McMahon M., McWalter G.K., McLellan L.I., Elcomb C.R., Henderson C.J., Wolf R.L., Moffat G.J., Itoh K., Yamamoto M., Hayes J.D. Loss of Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice. Biochem. J. 365:2002;405-416
-
(2002)
Biochem. J.
, vol.365
, pp. 405-416
-
-
Chanas, S.A.1
Jiang, Q.2
McMahon, M.3
McWalter, G.K.4
McLellan, L.I.5
Elcomb, C.R.6
Henderson, C.J.7
Wolf, R.L.8
Moffat, G.J.9
Itoh, K.10
Yamamoto, M.11
Hayes, J.D.12
-
10
-
-
13044304201
-
Nrf2 is essential for protection against acute pulmonary injury in mice
-
Chan K., Kan Y.W. Nrf2 is essential for protection against acute pulmonary injury in mice. Proc. Natl. Acad. Sci. USA. 96:1999;12731-12736
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12731-12736
-
-
Chan, K.1
Kan, Y.W.2
-
11
-
-
0035836698
-
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
-
Chan K., Han X.D., Kan Y.W. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc. Natl. Acad. Sci. USA. 98:2001;4611-4616
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4611-4616
-
-
Chan, K.1
Han, X.D.2
Kan, Y.W.3
-
12
-
-
0035153227
-
High sensitivity of Nr2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto A., Itoh K., Nagayoshi E., Haruta J., Kimura T., O'Connor T., Harada T., Yamamoto M. High sensitivity of Nr2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol. Sci. 59:2001;169-177
-
(2001)
Toxicol. Sci.
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
Harada, T.7
Yamamoto, M.8
-
13
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in Nrf2 transcription-deficient mice
-
Ramos-Gomez M., Kwak M.K., Dolan P.M., Itoh K., Yamamoto M., Talalay P., Kensler T.W. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in Nrf2 transcription-deficient mice. Proc. Natl. Acad. Sci. USA. 98:2001;3410-3415
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
14
-
-
0142148111
-
Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase alpha 3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element
-
Jowsey I.R., Jiang Q., Itoh K., Yamamoto M., Hayes J.D. Expression of the aflatoxin B1-8, 9-epoxide-metabolizing murine glutathione S-transferase alpha 3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element. Mol. Pharmacol. 64:2003;1018-1028
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 1018-1028
-
-
Jowsey, I.R.1
Jiang, Q.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
15
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13:1999;76-86
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
16
-
-
0013282861
-
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element
-
Nguyen T., Sherratt P.J., Huang H.-C., Yang C.S., Pickett C.B. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. J. Biol. Chem. 278:2003;4536-4541
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4536-4541
-
-
Nguyen, T.1
Sherratt, P.J.2
Huang, H.-C.3
Yang, C.S.4
Pickett, C.B.5
-
17
-
-
0037462651
-
Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
-
Stewart D., Killeen E., Naquin R., Alam S., Alam J. Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium. J. Biol. Chem. 278:2003;2396-2402
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2396-2402
-
-
Stewart, D.1
Killeen, E.2
Naquin, R.3
Alam, S.4
Alam, J.5
-
18
-
-
0036240610
-
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: Role of antioxidant response element-like sequences in the nrf2 promoter
-
Kwak M.-K., Itoh K., Yamamoto M., Kensler T.W. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter. Mol. Cell. Biol. 22:2002;2883-2892
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2883-2892
-
-
Kwak, M.-K.1
Itoh, K.2
Yamamoto, M.3
Kensler, T.W.4
-
19
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T., Itoh K., Takahashi S., Sato H., Yanagawa T., Katoh Y., Bannai S., Yamamoto M. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J. Biol. Chem. 275:2000;16023-16029
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
Sato, H.4
Yanagawa, T.5
Katoh, Y.6
Bannai, S.7
Yamamoto, M.8
-
20
-
-
0033731182
-
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2 related factor 2
-
Huang H.-C., Nguyen T., Pickett C.B. Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2 related factor 2. Proc. Natl. Acad. Sci. USA. 97:2000;12475-12480
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12475-12480
-
-
Huang, H.-C.1
Nguyen, T.2
Pickett, C.B.3
-
21
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon M., Itoh K., Yamamoto M., Hayes J.D. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J. Biol. Chem. 278:2000;21592-21600
-
(2000)
J. Biol. Chem.
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
22
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., O'Connor T., Yamamoto M. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells. 8:2003;379-381
-
(2003)
Genes Cells
, vol.8
, pp. 379-381
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
O'Connor, T.5
Yamamoto, M.6
-
23
-
-
0034595064
-
Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for γ-glutamylcysteine synthetase
-
Sekhar K.R., Soltaninassab S.R., Borrelli M.J., Xu Z.Q., Meredith M.J., Domann F.E., Freeman M.L. Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for γ-glutamylcysteine synthetase. Biochem. Biophys. Res. Commun. 270:2000;311-317
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.270
, pp. 311-317
-
-
Sekhar, K.R.1
Soltaninassab, S.R.2
Borrelli, M.J.3
Xu, Z.Q.4
Meredith, M.J.5
Domann, F.E.6
Freeman, M.L.7
-
24
-
-
0030881029
-
Activity of ubiquitin-dependent pathway in response to oxidative stress
-
Shang F., Gong X., Taylor A. Activity of ubiquitin-dependent pathway in response to oxidative stress. J. Biol. Chem. 272:1997;23086-23093
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23086-23093
-
-
Shang, F.1
Gong, X.2
Taylor, A.3
-
25
-
-
0242721624
-
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
-
Kwak M.-K., Wakabayashi N., Greenlaw J.L., Yamamoto M., Kensler T.W. Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway. Mol. Cell. Biol. 23:2003;8786-8794
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8786-8794
-
-
Kwak, M.-K.1
Wakabayashi, N.2
Greenlaw, J.L.3
Yamamoto, M.4
Kensler, T.W.5
-
26
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart C.M. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70:2001;503-533
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
27
-
-
0035292759
-
Themes and variations on ubiquitylations
-
Weissman A.M. Themes and variations on ubiquitylations. Nat. Rev. 2:2001;169-178
-
(2001)
Nat. Rev.
, vol.2
, pp. 169-178
-
-
Weissman, A.M.1
-
28
-
-
0025181418
-
Okadaic acid: A new probe for the study of cellular regulation
-
Cohen P., Holmes C.F.B., Tsukitani Y. Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem. Sci. 15:1990;98-102
-
(1990)
Trends Biochem. Sci.
, vol.15
, pp. 98-102
-
-
Cohen, P.1
Holmes, C.F.B.2
Tsukitani, Y.3
-
29
-
-
0033119627
-
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2
-
Unger T., Juven-Gershon T., Moallem E., Berger M., Vogt Sionov R., Lozano G., Oren M., Haupt Y. Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. EMBO J. 18:1999;1805-1814
-
(1999)
EMBO J.
, vol.18
, pp. 1805-1814
-
-
Unger, T.1
Juven-Gershon, T.2
Moallem, E.3
Berger, M.4
Vogt Sionov, R.5
Lozano, G.6
Oren, M.7
Haupt, Y.8
-
31
-
-
0035887213
-
Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover
-
Dumaz N., Milne D.M., Jardine L.J., Meek D.W. Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover. Biochem. J. 359:2001;459-464
-
(2001)
Biochem. J.
, vol.359
, pp. 459-464
-
-
Dumaz, N.1
Milne, D.M.2
Jardine, L.J.3
Meek, D.W.4
-
32
-
-
0033600914
-
Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals
-
Yu R., Lei W., Mandlejar S., Weber M.J., Der C.J., Wu J., Kong A.-N.T. Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals. J. Biol. Chem. 274:1999;27545-27552
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27545-27552
-
-
Yu, R.1
Lei, W.2
Mandlejar, S.3
Weber, M.J.4
Der, C.J.5
Wu, J.6
Kong, A.-N.T.7
-
33
-
-
0037044791
-
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
-
Huang H.-C., Nguyen T., Pickett C.B. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J. Biol. Chem. 277:2002;42769-42774
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42769-42774
-
-
Huang, H.-C.1
Nguyen, T.2
Pickett, C.B.3
-
34
-
-
0041742490
-
Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress
-
Numazawa S., Ishikawa M., Yoshida A., Tanaka S., Yoshida T. Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress. Am. J. Physiol. Cell. Physiol. 285:2003;C334-C342
-
(2003)
Am. J. Physiol. Cell. Physiol.
, vol.285
, pp. 334-C342
-
-
Numazawa, S.1
Ishikawa, M.2
Yoshida, A.3
Tanaka, S.4
Yoshida, T.5
-
35
-
-
0242666198
-
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
-
Bloom D.A., Jaiswal A.K. Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. J. Biol. Chem. 278:2003;44675-44682
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
36
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan S.B., Zhang D., Hannink M., Arvisais E., Kaufman R.J., Diehl J.A. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol. 23:2003;7198-7209
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
37
-
-
0033789011
-
The essential role of phosphatidylinositol 3-kinase and the p38 mitogen-activated protein kinase activation in the antioxidant response element-mediated rGSTA2 induction by decreased glutathione in H4IIE hepatoma cells
-
Kang K.W., Ryu J.H., Kim S.G. The essential role of phosphatidylinositol 3-kinase and the p38 mitogen-activated protein kinase activation in the antioxidant response element-mediated rGSTA2 induction by decreased glutathione in H4IIE hepatoma cells. Mol. Pharmacol. 58:2000;1017-1025
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1017-1025
-
-
Kang, K.W.1
Ryu, J.H.2
Kim, S.G.3
-
38
-
-
0035034848
-
Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells
-
Kang K.W., Cho M.K., Lee C.H., Kim S.G. Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells. Mol. Pharmacol. 59:2001;1147-1156
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1147-1156
-
-
Kang, K.W.1
Cho, M.K.2
Lee, C.H.3
Kim, S.G.4
-
39
-
-
0035827505
-
Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells
-
Lee J.-M., Hanson J.M., Chu W.A., Johnson J.A. Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells. J. Biol. Chem. 276:2001;20011-20016
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20011-20016
-
-
Lee, J.-M.1
Hanson, J.M.2
Chu, W.A.3
Johnson, J.A.4
-
40
-
-
0037016759
-
Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells
-
Li J., Lee J.-M., Johnson J.A. Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J. Biol. Chem. 277:2002;388-394
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 388-394
-
-
Li, J.1
Lee, J.-M.2
Johnson, J.A.3
-
41
-
-
0038537298
-
PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells
-
Nakaso K., Yano H., Fukuhara Y., Takeshima T., Wada-Isoe K., Nakashima K. PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells. FEBS Lett. 546:2003;181-184
-
(2003)
FEBS Lett.
, vol.546
, pp. 181-184
-
-
Nakaso, K.1
Yano, H.2
Fukuhara, Y.3
Takeshima, T.4
Wada-Isoe, K.5
Nakashima, K.6
-
42
-
-
1542335553
-
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3 kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical, carnosol
-
Martin D., Rojo A.I., Salinas M., Diaz R., Gallardo G., Alam J., Ruiz de Galarreta C.M., Cuadrado A. Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3 kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical, carnosol. J. Biol. Chem. 279:2004;8919-8929
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 8919-8929
-
-
Martin, D.1
Rojo, A.I.2
Salinas, M.3
Diaz, R.4
Gallardo, G.5
Alam, J.6
Ruiz De Galarreta, C.M.7
Cuadrado, A.8
-
43
-
-
0035963293
-
Functional characterization and role of Inrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase 1 gene
-
Dhakshinamoorthy S., Jaiswal A.K. Functional characterization and role of Inrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase 1 gene. Oncogene. 20:2001;3906-3917
-
(2001)
Oncogene
, vol.20
, pp. 3906-3917
-
-
Dhakshinamoorthy, S.1
Jaiswal, A.K.2
-
44
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogenesis and oxidants
-
Dinkova-Kostova A.T., Holtzclaw W.D., Cole R.N., Itoh K., Wakabayashi N., Katoh Y., Yamamoto M., Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogenesis and oxidants. Proc. Natl. Acad. Sci. USA. 99:2002;11908-11913
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
45
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang D.D., Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol. Cell. Biol. 23:2003;8137-8151
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
46
-
-
1642282736
-
Cellular mechanisms of redox cell signaling: The role of cysteine modification in controlling antioxidant defenses in response to electrophilic lipid oxidation products
-
Levonen A.-L., Landar A., Ramachandran A., Ceaser E.K., Dickinson D.A., Zanoni G., Morrow J.D., Darley-Usmar V. Cellular mechanisms of redox cell signaling: the role of cysteine modification in controlling antioxidant defenses in response to electrophilic lipid oxidation products. Biochem. J. 378:2004;373-382
-
(2004)
Biochem. J.
, vol.378
, pp. 373-382
-
-
Levonen, A.-L.1
Landar, A.2
Ramachandran, A.3
Ceaser, E.K.4
Dickinson, D.A.5
Zanoni, G.6
Morrow, J.D.7
Darley-Usmar, V.8
-
47
-
-
0037183998
-
The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm
-
Zipper L.M., Mulcahy R.T. The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm. J. Biol. Chem. 277:2002;36544-36552
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36544-36552
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
48
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi N., Itoh K., Wakabayashi J., Motohashi H., Noda S., Takahashi S., Imakado S., Kotsuji T., Otsuka F., Roop D.R., Harada T., Engel J.D., Yamamoto M. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat. Genet. 35:2003;238-245
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
Harada, T.11
Engel, J.D.12
Yamamoto, M.13
-
49
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
Kobayashi M., Itoh K., Suzuki T., Osanai H., Nishikawa K., Katoh Y., Takagi Y., Yamamoto M. Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells. 7:2002;807-820
-
(2002)
Genes Cells
, vol.7
, pp. 807-820
-
-
Kobayashi, M.1
Itoh, K.2
Suzuki, T.3
Osanai, H.4
Nishikawa, K.5
Katoh, Y.6
Takagi, Y.7
Yamamoto, M.8
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