LPS-Induced Formation of Immunoproteasomes: TNF-α and Nitric Oxide Production are Regulated by Altered Composition of Proteasome-Active Sites

Cell Biochemistry and Biophysics

Volumn 60, Issue 1-2, 2011, Pages 77-88

  Reis, Julia ^a,b   Guan, Xiu Qin ^a   Kisselev, Alexei F ^c   Papasian, Christopher J ^a   Qureshi, Asaf A ^a   Morrison, David C ^a   van Way III, Charles W ^b   Vogel, Stefanie N ^d   Qureshi, Nilofer ^a,b  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; Endotoxic shock; Inflammation; Nitric oxide

Indexed keywords

ACETYLCYSTEINE; AUTACOID; CYSTEINE PROTEINASE; DRUG DERIVATIVE; GAMMA INTERFERON; LACTACYSTIN; LIPOPOLYSACCHARIDE; LMP 2 PROTEIN; LMP-2 PROTEIN; LMP7 PROTEIN; NITRIC OXIDE; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEASOME; PROTEIN SUBUNIT; PSMB5 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; GENETICS; MACROPHAGE; METABOLISM; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; BLOTTING, WESTERN; CATALYTIC DOMAIN; CELL LINE; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; POLY I-C; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79955938496     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-011-9182-8     Document Type: Article

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