Stochastic and genetic factors influence tissue-specific decline in ageing C. Elegans

Nature

Volumn 419, Issue 6909, 2002, Pages 808-814

  Herndon, Laura A ^a   Schmeissner, Peter J ^a   Dudaronek, Justyna M ^a   Brown, Paula A ^a   Listner, Kristin M ^a   Sakano, Yuko ^a   Paupard, Marie C ^b   Hall, David H ^b   Driscoll, Monica ^a  

^a RUTGERS UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; CELLS; GENETIC ENGINEERING; PROTEINS;

GENETIC FACTORS;

TISSUE;

GREEN FLUORESCENT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE;

NEMATODE;

AGING; ARTICLE; BIOSYNTHESIS; CAENORHABDITIS ELEGANS; CELL TYPE; GENE EXPRESSION REGULATION; GENE MUTATION; LIFESPAN; LOCOMOTION; LONGEVITY; MUSCLE ATROPHY; NEMATODE; NERVE DEGENERATION; NERVOUS SYSTEM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STOCHASTIC MODEL; WORM;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0037167855     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01135     Document Type: Article

References (48)

1. Vanfleteren, J. R. & Braeckmari, B. P. Mechanisms' of life span determination in Caenorhabditis elegans. Neurobiol. Aging 20, 487-502 (1999).
2. Braeckman, B. P., Houthoofd, K. & Vanfleteren, J. R. Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans. Mech. Ageing Dev. 122, 673-693 (2001).
3. Lithgow, G. J. & Walker, G. A. Stress resistance as a determinate of C. Elegans lifespan. Mech. Ageing Dev. 123, 765-771 (2002).
4. Sulston, J. E. & Horvitz, H. R. Post embryonic cell lineages of the nematode Caenorhabditis elegans. Dev. Biol. 56, 110-156 (1977).
5. White J. G., Southgate, E., Thomson, J. N. & Brenner, S. The structure of the nervous system of Caenorhabditis elegans. Phil. Trans. R. Soc. Lond. B 314, 1-340 (1986).
6. Klass, M. R. Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span. Mech. Ageing Dev. 6, 413-429 (1977).
7. Bolanowski, M. A., Jacobson, L. A. & Russell, R. L. Quantitative measures of aging in the nematode Caenorhabditis elegans. II. Lysosomal hydrolases as markers of senescence. Mech. Ageing Dev. 21, 295-319 (1983).
8. Driscoll, M. Cell death in C. Elegans: Molecular insights into mechanisms conserved between nematodes and mammals. Brain Pathol. 6, 411-425 (1996).
9. Johnson, T. E. Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 84, 3777-3781 (1987).
10. Hall, D. H. et al. Neuropathology of degenerative cell death in C. Elegans. J. Neurosci. 17, 1033-1045 (1997)
11. Maduro, M. & Pilgrim, D. Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system. Genetics 141, 977-988 (1995).
12. Mitani, S., Du, H., Hall, D. H., Driscoll, M. & Chalfie, M. Combinatorial control of touch receptor neuron expression in Caenorhabditis elegans. Development 119, 773-783 (1993).
13. Colavita, A., Krishna, S., Zheng, H., Padgett, R. W. & Culotti, J. G. Pioneer axon guidance by UNC-129, a C. Elegans TGF-β. Science 281, 706-709 (1998).
14. Apfeld, J. & Kenyon, C. Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402, 804-809 (1999).
15. Perkins, L. A., Hedgecock, E. M., Thomson, J. N. & Culotti, J. G. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev. Biol. 117, 456-487 (1986).
16. Campagnola, P. J. et al. Three-dimensional high-resolution second-harmonic generation imaging of endogenous structural proteins in biological tissues. Biophys. J. 82, 493-508 (2002).
17. Epstein, J., Himmelhoch, S. & Gershon, D. Studies on ageing in nematodes. III. Electron microscopical studies on age-associated cellular damage. Mech. Ageing Dev. 1, 245-255 (1972).
18. Hall, D. H. et al. Ultrastructural features of the adult hermaphrodite gonad of Caenorhabditis elegans: Relations between the germ line and soma. Dev. Biol. 212, 101-123 (1999).
19. Kimura, K. D., Tissenbaum, H. A., Liu, Y. & Ruvkun, G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946 (1997).
20. Friedman, D. B. & Johnson, T. E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118, 75-86 (1988).
21. Duhon, S. A. & Johnson, T. E. Movement as an index of vitality: Comparing wild type and the age-1 mutant of Caenorhabditis elegans. J. Gerontol. A Biol. Sci. Med. Sci. 50, B254-B261 (1995).
22. Bolanowski, M. A., Russell, R. L. & Jacobson, L. A. Quantitative measures of aging in the nematode Caenorhabditis elegans. I. Population and longitudinal studies of two behavioral parameters. Mech. Ageing Dev. 15, 279-295 (1981).
23. Kirkwood, T. B. Evolution of ageing. Nature 270, 301-304 (1977).
24. Kirkwood, T. B. Human senescence. BioEssays 18, 1009-1016 (1996).
25. Kirkwood, T. B. Changing complexity in aging: A metric not an hypothesis. Neurobiol. Aging 23, 21-22. (2002).
26. Johnson, T. E. et al. Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans. Exp. Gerontol. 36, 1609-1617 (2001).
27. Finch, C. E. & Kirkwood, T. B. L. Chance, Development, and Aging (Oxford Univ. Press, New York, 2000).
28. Sozou, P. D. & Kirkwood, T. B. A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA. J. Theor. Biol. 213, 573-586 (2001).
29. Kirkwood, T. B. Evolution of ageing. Mech. Ageing Dev. 123, 737-745 (2002).
30. Leonard, D. S., Bowman, V. D., Ready, D. F. & Pak, W. L. Degeneration of photoreceptors in rhodopsin mutants of Drosophila. J. Neurobiol. 23, 605-626 (1992).
31. Helfand, S. L. & Naprta, B. The expression of a reporter protein, β-galactosidase, is preserved during maturation and aging in some cells of the adult Drosophila melanogaster. Mech. Dev. 55, 45-51 (1996).
32. Morrison, J. H. & Hof, P. R. Life and death of neurons in the aging brain. Science 278, 412-419 (1997).
33. Jucker, M., Bondolfi, L., Calhoun, M. E., Long, J. M. & Ingram, D. K. Structural brain aging in inbred mice: Potential for genetic linkage. Exp. Gerontol. 35, 1383-1388 (2000).
34. Waterston, R. H. The Nematode: Caenorhabditis Elegans (ed. Wood, W. B.) 281-337 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1988).
35. Hughes, S. M. & Schiaffino, S. Control of muscle fibre size: A crucial factor in ageing. Acta Physiol. Scand. 167, 307-312 (1999).
36. Fujisawa, K. Some observations on the skeletal musculature of aged rats. Part 2. Fine morphology of diseased muscle fibres J. Neurol. Sci. 24, 447-469 (1975).
37. Takahashi, A., Philpott, D. E. & Miquel, J. Electron microscope studies on aging Drosophila melanogaster. 3. Flight muscle. J. Gerontol. 25, 222-228 (1970).
38. Arantes-Oliveira, N., Apfeld, J., Dillin, A. & Kenyon, C. Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295, 502-505 (2002).
39. Garigan, D. et al. Genetic analysis of tissue aging in Caenorhabditis elegans. A role for heat-shock factor and bacterial proliferation. Genetics 161, 1101-1112 (2002).
40. Wolkow, C. A., Kimura, K. D., Lee, M. S. & Ruvkun, G. Regulation of C. Elegans life-span by insulin like signaling in the nervous system. Science 290, 147-150 (2000).
41. Hsin, H. & Kenyon, C. Signals from the reproductive system regulate the lifespan of C. Elegans. Nature 399, 362-366 (1999).
42. Lund, J. et al. Global profiles of aging in Caenorhabditis elegans. Curr. Biol. 12, 1566-1573 (2002).
43. Johnson, T. E. & McCaffrey, G. Programmed aging or error catastrophe? An examination by two-dimensional polyacrylamide gel electrophoresis. Mech. Ageing Dev. 30, 285-297 (1985).
44. Rogina, B., Vaupel, J. W., Partridge, L. & Helfand, S. L. Regulation of gene expression is preserved in aging Drosophila melanogaster. Curr. Biol. 8, 475-478 (1998).
45. Lewis, J. A. & Fleming, J. T. Caenorhabditis elegans. Modern Biological Analysis of an Organism (eds Epstein, H. F. & Shakes, D. C.) 4-27 (Academic, San Diego, 1995).
46. Hall, D. H. Electron microscopy and three-dimensional image reconstruction. Methods Cell BioL 48, 395-436 (1995).
47. Paupard, M. C., Miller, A., Grant, B., Hirsh, D. & Hall, D. H. Immuno-EM localization of GFP-tagged yolk proteins in C. Elegans using microwave fixation. J. Histochem. Cytochem. 49, 949-956 (2001).
48. Hedgecock, E. M., Culotti, J. G., Thomson, J. N. & Perkins, L. A. Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes. Dev. Biol. 111, 158-170 (1985).