Tragedy in a heartbeat: Malfunctioning desmin causes skeletal and cardiac muscle disease

Journal of Clinical Investigation

Volumn 119, Issue 7, 2009, Pages 1806-1813

  Goldfarb, Lev G ^a   Dalakas, Marinos C ^b  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAB CRYSTALLIN; CHAPERONE; DESMIN; DYSTROPHIN; HEAT SHOCK PROTEIN; INTERMEDIATE FILAMENT PROTEIN; LAMIN A; LAMIN C; MYOTILIN; UBIQUITIN; UNCLASSIFIED DRUG; ALPHA CRYSTALLIN; CRYAB PROTEIN, HUMAN;

ASSISTIVE TECHNOLOGY DEVICE; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE INHERITANCE; CARDIOMYOPATHY; CHEST INFECTION; CHROMOSOME 2Q; CLINICAL ASSESSMENT; DESMINOPATHY; DISEASE COURSE; DYSPNEA; EARLY DIAGNOSIS; ELECTROCARDIOGRAM; ELECTROMYOGRAM; GASTROCNEMIUS MUSCLE; GENE LOCATION; GENETIC VARIABILITY; GLUTEUS MAXIMUS MUSCLE; GRACILIS FLAP; HEART ARRHYTHMIA; HEART FAILURE; HEART TRANSPLANTATION; HUMAN; HYPERCAPNIA; METABOLIC DISORDER; MICROFILAMENT; MOLECULAR BIOLOGY; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE WEAKNESS; MUTATION; MYOPATHY; NONHUMAN; PATHOGENESIS; PERONEUS MUSCLE; PHENOTYPE; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN STRUCTURE; RECTUS FEMORIS MUSCLE; RESPIRATORY DISTRESS; REVIEW; RISK ASSESSMENT; SARTORIUS MUSCLE; SKELETAL MUSCLE; SOLEUS MUSCLE; TIBIALIS ANTERIOR MUSCLE; VASTUS LATERALIS MUSCLE; ANIMAL; CARDIOMYOPATHIES; CHEMISTRY; DISEASE MODEL; GENETICS; MUSCULAR DISEASES; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

ALPHA-CRYSTALLIN B CHAIN; ANIMALS; CARDIOMYOPATHIES; DESMIN; DISEASE MODELS, ANIMAL; HUMANS; MUSCULAR DISEASES; MUTATION; PHENOTYPE; PROTEIN STRUCTURE, SECONDARY;

EID: 68849104798     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI38027     Document Type: Review

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