Regulation of Akt signaling by sirtuins its implication in cardiac hypertrophy and aging

Circulation Research

Volumn 114, Issue 2, 2014, Pages 368-378

  Pillai, Vinodkumar B ^a   Sundaresan, Nagalingam R ^a   Gupta, Mahesh P ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Aging; Cardiac hypertrophy; Sirtuins

Indexed keywords

ACYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; SIRTUIN; SIRTUIN 1; SIRTUIN 3; SIRTUIN 6; SIRTUIN DEACETYLASE; UNCLASSIFIED DRUG; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; POLYPHOSPHOINOSITIDE; REACTIVE OXYGEN METABOLITE;

AGING; ANGIOGENESIS; APOPTOSIS; AUTOPHAGY; CELL AGING; CELL GROWTH; CELL MEMBRANE; CHROMATIN; DEACETYLATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART VENTRICLE HYPERTROPHY; HUMAN; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; UBIQUITINATION; ANIMAL; CARDIOMEGALY; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENZYMOLOGY; HEART MUSCLE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION;

AGING; CARDIAC HYPERTROPHY; SIRTUINS;

AGING; ANIMALS; CARDIOMEGALY; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENZYME ACTIVATION; HUMANS; MYOCARDIUM; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SIRTUINS; UBIQUITINATION;

EID: 84897112785     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.300536     Document Type: Review

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