메뉴 건너뛰기




Volumn 25, Issue 5, 2005, Pages 1869-1878

Role for Akt3/protein kinase by in attainment of normal brain size

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN AKT1; PROTEIN AKT3; PROTEIN KINASE B; PROTEIN KINASE B BETA; RAPAMYCIN; UNCLASSIFIED DRUG;

EID: 20044382806     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.5.1869-1878.2005     Document Type: Article
Times cited : (505)

References (76)
  • 1
    • 0028032895 scopus 로고
    • Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
    • Araki, E., M. A. Lipes, M. E. Patti, J. C. Bruning, B. Haag III, R. S. Johnson, and C. R. Kahn. 1994. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 372:186-190.
    • (1994) Nature , vol.372 , pp. 186-190
    • Araki, E.1    Lipes, M.A.2    Patti, M.E.3    Bruning, J.C.4    Haag III, B.5    Johnson, R.S.6    Kahn, C.R.7
  • 3
    • 1542781732 scopus 로고    scopus 로고
    • Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B
    • Bae, S. S., C. Han, J. Mu, and M. J. Birnbaum. 2003. Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B. J. Biol. Chem. 278:49530-49536.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49530-49536
    • Bae, S.S.1    Han, C.2    Mu, J.3    Birnbaum, M.J.4
  • 4
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker, J., J. P. Liu, E. J. Robertson, and A. Efstratiadis. 1993. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75:73-82.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 5
    • 0032512587 scopus 로고    scopus 로고
    • Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes
    • Barthel, A., K. Nakatani, A. A. Dandekar, and R. A. Roth. 1998. Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 243:509-513.
    • (1998) Biochem. Biophys. Res. Commun. , vol.243 , pp. 509-513
    • Barthel, A.1    Nakatani, K.2    Dandekar, A.A.3    Roth, R.A.4
  • 6
    • 0028941681 scopus 로고
    • Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons
    • Beck, K. D., L. Powell-Braxton, H. R. Widmer, J. Valverde, and F. Hefti. 1995. Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron 14:717-730.
    • (1995) Neuron , vol.14 , pp. 717-730
    • Beck, K.D.1    Powell-Braxton, L.2    Widmer, H.R.3    Valverde, J.4    Hefti, F.5
  • 8
    • 2342565881 scopus 로고    scopus 로고
    • Advances in protein kinase B signalling: AKTion on multiple fronts
    • Brazil, D. P., Z. Z. Yang, and B. A. Hemmings. 2004. Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem. Sci. 29:233-242.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 233-242
    • Brazil, D.P.1    Yang, Z.Z.2    Hemmings, B.A.3
  • 9
    • 0033515625 scopus 로고    scopus 로고
    • A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain
    • Brodbeck, D., P. Cron, and B. A. Hemmings. 1999. A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain. J. Biol. Chem. 274:9133-9136.
    • (1999) J. Biol. Chem. , vol.274 , pp. 9133-9136
    • Brodbeck, D.1    Cron, P.2    Hemmings, B.A.3
  • 10
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L. C. 2002. The phosphoinositide 3-kinase pathway. Science 296:1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 11
    • 0027269766 scopus 로고
    • Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice
    • Carson, M. J., R. R. Behringer, R. L. Brinster, and F. A. McMorris. 1993. Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron 10:729-740.
    • (1993) Neuron , vol.10 , pp. 729-740
    • Carson, M.J.1    Behringer, R.R.2    Brinster, R.L.3    McMorris, F.A.4
  • 12
    • 0030060198 scopus 로고    scopus 로고
    • The Drosophila insulin receptor is required for normal growth
    • Chen, C., J. Jack, and R. S. Garofalo. 1996. The Drosophila insulin receptor is required for normal growth. Endocrinology 137:846-856.
    • (1996) Endocrinology , vol.137 , pp. 846-856
    • Chen, C.1    Jack, J.2    Garofalo, R.S.3
  • 17
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • Cho, H., J. L. Thorvaldsen, Q. Chu, F. Feng, and M. J. Birnbaum. 2001. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276:38349-38352.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 18
    • 0033593316 scopus 로고    scopus 로고
    • Size control in animal development
    • Conlon, I., and M. Raff. 1999. Size control in animal development. Cell 96:235-244.
    • (1999) Cell , vol.96 , pp. 235-244
    • Conlon, I.1    Raff, M.2
  • 20
    • 0032522924 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons
    • Crowder, R. J., and R. S. Freeman. 1998. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. J. Neurosci. 18:2933-2943.
    • (1998) J. Neurosci. , vol.18 , pp. 2933-2943
    • Crowder, R.J.1    Freeman, R.S.2
  • 21
    • 0018372689 scopus 로고
    • Comparative aspects of the brain growth spurt
    • Dobbing, J., and J. Sands. 1979. Comparative aspects of the brain growth spurt. Early Hum. Dev. 3:79-83.
    • (1979) Early Hum. Dev. , vol.3 , pp. 79-83
    • Dobbing, J.1    Sands, J.2
  • 23
    • 0036738462 scopus 로고    scopus 로고
    • PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium
    • Dupont, J., J. P. Renou, M. Shani, L. Hennighausen, and D. LeRoith. 2002. PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium. J. Clin. Investig. 110:815-825.
    • (2002) J. Clin. Investig. , vol.110 , pp. 815-825
    • Dupont, J.1    Renou, J.P.2    Shani, M.3    Hennighausen, L.4    Leroith, D.5
  • 24
    • 0031740792 scopus 로고    scopus 로고
    • Genetics of mouse growth
    • Efstratiadis, A. 1998. Genetics of mouse growth. Int. J. Dev. Biol. 42:955-976.
    • (1998) Int. J. Dev. Biol. , vol.42 , pp. 955-976
    • Efstratiadis, A.1
  • 25
    • 0842310838 scopus 로고    scopus 로고
    • Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia
    • Emamian, E. S., D. Hall, M. J. Birnbaum, M. Karayiorgou, and J. A. Gogos. 2004. Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat. Genet. 36:131-137.
    • (2004) Nat. Genet. , vol.36 , pp. 131-137
    • Emamian, E.S.1    Hall, D.2    Birnbaum, M.J.3    Karayiorgou, M.4    Gogos, J.A.5
  • 26
    • 0142244688 scopus 로고    scopus 로고
    • Schizophrenia
    • Freedman, R. 2003. Schizophrenia. N. Engl. J. Med. 349:1738-1749.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 1738-1749
    • Freedman, R.1
  • 27
    • 2342667375 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling
    • Fruman, D. A. 2004. Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling. Curr. Opin. Immunol. 16:314-320.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 314-320
    • Fruman, D.A.1
  • 28
    • 0036584593 scopus 로고    scopus 로고
    • Genetic analysis of insulin signaling in Drosophila
    • Garofalo, R. S. 2002. Genetic analysis of insulin signaling in Drosophila. Trends Endocrinol. Metab. 13:156-162.
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 156-162
    • Garofalo, R.S.1
  • 31
    • 4243167848 scopus 로고    scopus 로고
    • How are the sizes of cells, organs, and bodies controlled?
    • Hafen, E., and H. Stocker. 2003. How are the sizes of cells, organs, and bodies controlled? PLoS Biol. 1:E86.
    • (2003) PLoS Biol. , vol.1
    • Hafen, E.1    Stocker, H.2
  • 36
    • 0242268407 scopus 로고    scopus 로고
    • mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
    • Kwon, C. H., X. Zhu, J. Zhang, and S. J. Baker. 2003. mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc. Natl. Acad. Sci. USA 100:12923-12928.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12923-12928
    • Kwon, C.H.1    Zhu, X.2    Zhang, J.3    Baker, S.J.4
  • 38
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • LeRoith, D., and C. T. Roberts, Jr. 2003. The insulin-like growth factor system and cancer. Cancer Lett. 195:127-137.
    • (2003) Cancer Lett. , vol.195 , pp. 127-137
    • LeRoith, D.1    Roberts Jr., C.T.2
  • 40
    • 0037215682 scopus 로고    scopus 로고
    • PTEN regulation of neural development and CNS stem cells
    • Li, L., F. Liu, and A. H. Ross. 2003. PTEN regulation of neural development and CNS stem cells. J. Cell Biochem. 88:24-28.
    • (2003) J. Cell Biochem. , vol.88 , pp. 24-28
    • Li, L.1    Liu, F.2    Ross, A.H.3
  • 41
    • 2342618936 scopus 로고    scopus 로고
    • Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
    • Liang, J., and J. M. Slingerland. 2003. Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2:339-345.
    • (2003) Cell Cycle , vol.2 , pp. 339-345
    • Liang, J.1    Slingerland, J.M.2
  • 42
    • 0035855710 scopus 로고    scopus 로고
    • A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala
    • Lin, C. H., S. H. Yeh, K. T. Lu, T. H. Leu, W. C. Chang, and P. W. Gean. 2001. A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala. Neuron 31:841-851.
    • (2001) Neuron , vol.31 , pp. 841-851
    • Lin, C.H.1    Yeh, S.H.2    Lu, K.T.3    Leu, T.H.4    Chang, W.C.5    Gean, P.W.6
  • 43
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu, J. P., J. Baker, A. S. Perkins, E. J. Robertson, and A. Efstratiadis. 1993. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:59-72.
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 44
    • 0035175162 scopus 로고    scopus 로고
    • Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth
    • Lupu, F., J. D. Terwilliger, K. Lee, G. V. Segre, and A. Efstratiadis. 2001. Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev. Biol. 229:141-162.
    • (2001) Dev. Biol. , vol.229 , pp. 141-162
    • Lupu, F.1    Terwilliger, J.D.2    Lee, K.3    Segre, G.V.4    Efstratiadis, A.5
  • 46
    • 0037014483 scopus 로고    scopus 로고
    • Raf and Akt mediate distinct aspects of sensory axon growth
    • Markus, A., J. Zhong, and W. D. Snider. 2002. Raf and Akt mediate distinct aspects of sensory axon growth. Neuron 35:65-76.
    • (2002) Neuron , vol.35 , pp. 65-76
    • Markus, A.1    Zhong, J.2    Snider, W.D.3
  • 47
    • 0019362830 scopus 로고
    • Relative brain size and basal metabolic rate in terrestrial vertebrates
    • Martin, R. D. 1981. Relative brain size and basal metabolic rate in terrestrial vertebrates. Nature 293:57-60.
    • (1981) Nature , vol.293 , pp. 57-60
    • Martin, R.D.1
  • 52
    • 0004214945 scopus 로고
    • Plenum Press, New York, N.Y.
    • Morell, P. (ed.). 1984. Myelin, 2nd ed. Plenum Press, New York, N.Y.
    • (1984) Myelin, 2nd Ed.
    • Morell, P.1
  • 53
    • 0035719947 scopus 로고    scopus 로고
    • Distinct and overlapping functions of insulin and IGF-I receptors
    • Nakae, J., Y. Kido, and D. Accili. 2001. Distinct and overlapping functions of insulin and IGF-I receptors. Endocr. Rev. 22:818-835.
    • (2001) Endocr. Rev. , vol.22 , pp. 818-835
    • Nakae, J.1    Kido, Y.2    Accili, D.3
  • 54
  • 55
    • 0242664808 scopus 로고    scopus 로고
    • Body building: Regulation of shape and size by PI3K/ TOR signaling during development
    • Neufeld, T. P. 2003. Body building: regulation of shape and size by PI3K/ TOR signaling during development. Mech. Dev. 120:1283-1296.
    • (2003) Mech. Dev. , vol.120 , pp. 1283-1296
    • Neufeld, T.P.1
  • 56
    • 0036713481 scopus 로고    scopus 로고
    • The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels
    • Oldham, S., H. Stocker, M. Laffargue, F. Wittwer, M. Wymann, and E. Hafen. 2002. The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development 129:4103-4109.
    • (2002) Development , vol.129 , pp. 4103-4109
    • Oldham, S.1    Stocker, H.2    Laffargue, M.3    Wittwer, F.4    Wymann, M.5    Hafen, E.6
  • 60
    • 0002356589 scopus 로고
    • Cardiac growth, maturation and aging
    • R. Zak (ed.), Raven Press, Ltd., New York, N.Y.
    • Rakusan, K. 1984. Cardiac growth, maturation and aging, p. 131-164. In R. Zak (ed.), Growth of the heart in health and disease. Raven Press, Ltd., New York, N.Y.
    • (1984) Growth of the Heart in Health and Disease , pp. 131-164
    • Rakusan, K.1
  • 62
    • 0035489468 scopus 로고    scopus 로고
    • PKB/AKT: Functional insights from genetic models
    • Scheid, M. P., and J. R. Woodgett. 2001. PKB/AKT: functional insights from genetic models. Nat. Rev. Mol. Cell Biol. 2:760-768.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 760-768
    • Scheid, M.P.1    Woodgett, J.R.2
  • 64
    • 0035929596 scopus 로고    scopus 로고
    • The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival
    • Schwartzbauer, G., and J. Robbins. 2001. The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival. J. Biol. Chem. 276:35786-35793.
    • (2001) J. Biol. Chem. , vol.276 , pp. 35786-35793
    • Schwartzbauer, G.1    Robbins, J.2
  • 68
    • 0032496049 scopus 로고    scopus 로고
    • Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner
    • Summers, S. A., L. Lipfert, and M. J. Birnbaum. 1998. Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner. Biochem. Biophys. Res. Commun. 246:76-81.
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 76-81
    • Summers, S.A.1    Lipfert, L.2    Birnbaum, M.J.3
  • 69
    • 0042200238 scopus 로고    scopus 로고
    • In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain
    • Tsuji, R., M. Guizzetti, and L. G. Costa. 2003. In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain. Neuroreport 14:1395-1399.
    • (2003) Neuroreport , vol.14 , pp. 1395-1399
    • Tsuji, R.1    Guizzetti, M.2    Costa, L.G.3
  • 71
    • 0033258521 scopus 로고    scopus 로고
    • Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB
    • Verdu, J., M. A. Buratovich, E. L. Wilder, and M. J. Birnbaum. 1999. Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB. Nat. Cell Biol. 1:500-506.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 500-506
    • Verdu, J.1    Buratovich, M.A.2    Wilder, E.L.3    Birnbaum, M.J.4
  • 75
    • 0030806718 scopus 로고    scopus 로고
    • Insulin-like growth factor I gene deletion causing intrauterine growth retardation and severe short stature
    • Woods, K. A., C. Camacho-Hubner, D. Barter, A. J. Clark, and M. O. Savage. 1997. Insulin-like growth factor I gene deletion causing intrauterine growth retardation and severe short stature. Acta Paediatr. 423(Suppl.):39-45.
    • (1997) Acta Paediatr. , vol.423 , Issue.SUPPL. , pp. 39-45
    • Woods, K.A.1    Camacho-Hubner, C.2    Barter, D.3    Clark, A.J.4    Savage, M.O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.