-
2
-
-
0036596625
-
Endogenous oxidative stress: Relationship to aging, longevity and caloric restriction
-
G. Barja Endogenous oxidative stress: relationship to aging, longevity and caloric restriction Ageing Res. Rev. 2002 397 411
-
(2002)
Ageing Res. Rev.
, pp. 397-411
-
-
Barja, G.1
-
3
-
-
0036068641
-
Bone formation in the context of growth retardation induced by hIGFBP-1 overexpression in transgenic mice
-
N. Ben Lagha, P. Menuelle, D. Seurin, M. Binoux, Y. Lebouc, and A. Berdal Bone formation in the context of growth retardation induced by hIGFBP-1 overexpression in transgenic mice Connect. Tissue Res. 2002 515 519
-
(2002)
Connect. Tissue Res.
, pp. 515-519
-
-
Ben Lagha, N.1
Menuelle, P.2
Seurin, D.3
Binoux, M.4
Lebouc, Y.5
Berdal, A.6
-
5
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the Sirt1 deacetylase
-
A. Brunet, L.B. Sweeney, J.F. Sturgill, K.F. Chua, P.L. Greer, Y. Lin, H. Tran, S.E. Ross, R. Mostoslavsky, H.Y. Cohen, L.S. Hu, H.L. Cheng, M.P. Jedrychowski, S.P. Gygi, D.A. Sinclair, F.W. Alt, and M.E. Greenberg Stress-dependent regulation of FOXO transcription factors by the Sirt1 deacetylase Science 2004 2011 2015
-
(2004)
Science
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
7
-
-
0036606952
-
A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan
-
C.S. Carter, M.M. Ramsey, and W.E. Sonntag A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan Trends Genet. 2002 295 301
-
(2002)
Trends Genet.
, pp. 295-301
-
-
Carter, C.S.1
Ramsey, M.M.2
Sonntag, W.E.3
-
8
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
H. Daitoku, M. Hatta, H. Matsuzaki, S. Aratani, T. Ohshima, M. Miyagishi, T. Nakajima, and A. Fukamizu Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity Proc. Natl. Acad. Sci. 2004 10042 10047
-
(2004)
Proc. Natl. Acad. Sci.
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
9
-
-
24344447647
-
Visualization of the fetal skeletal system by double staining with alizarin red and alcian blue
-
D. Erdogan, D. Kadioglu, and T. Peker Visualization of the fetal skeletal system by double staining with alizarin red and alcian blue Turkey Gazi Med. J. 1995 55 58
-
(1995)
Turkey Gazi Med. J.
, pp. 55-58
-
-
Erdogan, D.1
Kadioglu, D.2
Peker, T.3
-
10
-
-
4444297565
-
Mitochondria: Are they the seat of senescence?
-
I. Fridovich Mitochondria: are they the seat of senescence? Aging Cell 2004 13 16
-
(2004)
Aging Cell
, pp. 13-16
-
-
Fridovich, I.1
-
11
-
-
0030999590
-
Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: Repercussions on reproduction, anti- and perinatal mortality and postnatal growth
-
E. Gay, D. Seurin, S. Babajko, S. Doublier, M. Cazillis, and M. Binoux Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: repercussions on reproduction, anti- and perinatal mortality and postnatal growth Endocrinology 1997 2937 2947
-
(1997)
Endocrinology
, pp. 2937-2947
-
-
Gay, E.1
Seurin, D.2
Babajko, S.3
Doublier, S.4
Cazillis, M.5
Binoux, M.6
-
13
-
-
24344473230
-
-
in preparation.
-
Kamel, C., Abrol, M., He, X., McBurney, M.W., 2005. SirT1 fails to p53-mediated biological functions. in preparation.
-
(2005)
SirT1 Fails to p53-mediated Biological Functions
-
-
Kamel, C.1
Abrol, M.2
He, X.3
McBurney, M.W.4
-
14
-
-
0035917440
-
A conserved regulatory system for aging
-
C. Kenyon A conserved regulatory system for aging Cell 2001 165 168
-
(2001)
Cell
, pp. 165-168
-
-
Kenyon, C.1
-
15
-
-
0345447590
-
Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
-
N. Libina, J.R. Berman, and C. Kenyon Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan Cell 2003 489 502
-
(2003)
Cell
, pp. 489-502
-
-
Libina, N.1
Berman, J.R.2
Kenyon, C.3
-
16
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
S.J. Lin, P.A. Defossez, and L. Guarente Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae Science 2000 2126 2128
-
(2000)
Science
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
17
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
J.P. Liu, J. Baker, A.S. Perkins, E.J. Robertson, and A. Efstratiadis Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) Cell 1993 59 72
-
(1993)
Cell
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
18
-
-
0037470488
-
Evolutionary medicine: From dwarf model systems to healthy centenarians?
-
V.D. Longo, and C.E. Finch Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 2003 1342 1346
-
(2003)
Science
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
19
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
J. Luo, A.Y. Nikolaev, S. Imai, D. Chen, F. Su, A. Shiloh, L. Guarente, and W. Gu Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 2001 137 148
-
(2001)
Cell
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
20
-
-
1042266548
-
Modulation of mammalian life span by the short isoform of p53
-
B. Maier, W. Gluba, B. Bernier, T. Turner, K. Mohammad, T. Guise, A. Sutherland, M. Thorner, and H. Scrable Modulation of mammalian life span by the short isoform of p53 Genes Dev. 2004 306 319
-
(2004)
Genes Dev.
, pp. 306-319
-
-
Maier, B.1
Gluba, W.2
Bernier, B.3
Turner, T.4
Mohammad, K.5
Guise, T.6
Sutherland, A.7
Thorner, M.8
Scrable, H.9
-
21
-
-
0037207475
-
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis
-
M.W. McBurney, X. Yang, K. Jardine, M. Hixon, K. Boekelheide, J.R. Webb, P.M. Lansdorp, and M. Lemieux The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis Mol. Cell Biol. 2003 38 54
-
(2003)
Mol. Cell Biol.
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
Lansdorp, P.M.7
Lemieux, M.8
-
22
-
-
0037410568
-
A low-fat, whole-food vegan diet, as well as other strategies that down-regulate IGF-I activity, may slow the human aging process
-
M.F. McCarty A low-fat, whole-food vegan diet, as well as other strategies that down-regulate IGF-I activity, may slow the human aging process Med. Hypotheses 2003 784 792
-
(2003)
Med. Hypotheses
, pp. 784-792
-
-
McCarty, M.F.1
-
23
-
-
1342264308
-
Mammalian Sirt1 represses forkhead transcription factors
-
M.C. Motta, N. Divecha, M. Lemieux, C. Kamel, D. Chen, W. Gu, Y. Bultsma, M. McBurney, and L. Guarente Mammalian Sirt1 represses forkhead transcription factors Cell 2004 551 563
-
(2004)
Cell
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
24
-
-
0025002570
-
Chromosomal localization of zfx - A human gene that escapes X inactivation - And its murine homologs
-
D.C. Page, C.M. Disteche, E.M. Simpson, A. De La Chapelle, M. Andersson, T. Alitalo, L.G. Brown, P. Green, and G. Akots Chromosomal localization of zfx - a human gene that escapes X inactivation - and its murine homologs Genomics 1990 37 46
-
(1990)
Genomics
, pp. 37-46
-
-
Page, D.C.1
Disteche, C.M.2
Simpson, E.M.3
De La Chapelle, A.4
Andersson, M.5
Alitalo, T.6
Brown, L.G.7
Green, P.8
Akots, G.9
-
25
-
-
0038624395
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
-
X.D. Peng, P.Z. Xu, M.L. Chen, A. Hahn-Windgassen, J. Skeen, J. Jacobs, D. Sundararajan, W.S. Chen, S.E. Crawford, K.G. Coleman, and N. Hay Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2 Genes Dev. 2003 1352
-
(2003)
Genes Dev.
, pp. 1352
-
-
Peng, X.D.1
Xu, P.Z.2
Chen, M.L.3
Hahn-Windgassen, A.4
Skeen, J.5
Jacobs, J.6
Sundararajan, D.7
Chen, W.S.8
Crawford, S.E.9
Coleman, K.G.10
Hay, N.11
-
26
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
S. Rozen, and H. Skaletsky Primer3 on the WWW for general users and for biologist programmers Meth. Mol. Biol 2000 365 386
-
(2000)
Meth. Mol. Biol
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.2
-
27
-
-
4444300675
-
What's new in the IGF-binding proteins?
-
S.A. Rosenzweig What's new in the IGF-binding proteins? Growth Horm. IGF Res. 2004 329 336
-
(2004)
Growth Horm. IGF Res.
, pp. 329-336
-
-
Rosenzweig, S.A.1
-
28
-
-
1642569707
-
Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice
-
D.A.M. Salih, G. Tripathi, C. Holding, T.A.M. Szestak, M.I. Gonzalez, E.J. Carter, L.J. Cobb, J.E. Eisemann, and J.M. Pell Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice Proc. Natl. Acad. Sci. 2004 4314 4319
-
(2004)
Proc. Natl. Acad. Sci.
, pp. 4314-4319
-
-
Salih, D.A.M.1
Tripathi, G.2
Holding, C.3
Szestak, T.A.M.4
Gonzalez, M.I.5
Carter, E.J.6
Cobb, L.J.7
Eisemann, J.E.8
Pell, J.M.9
-
29
-
-
0004136246
-
-
A Laboratory Manual Harbour Laboratory Press Cold Spring Harbour, New York
-
J. Sambrook, E.F. Fritsch, and T. Maniatis Molecular Cloning 1989 A Laboratory Manual Harbour Laboratory Press Cold Spring Harbour, New York
-
(1989)
Molecular Cloning
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
30
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
M. Tatar, A. Bartke, and A. Antebi The endocrine regulation of aging by insulin-like signals Science 2003 1346 1351
-
(2003)
Science
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
31
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
H.A. Tissenbaum, and L. Guarente Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 2001 227 230
-
(2001)
Nature
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
32
-
-
0036805791
-
Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
-
C. Tsigos, and G.P. Chrousos Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress J. Psychosom. Res. 2002 865 871
-
(2002)
J. Psychosom. Res.
, pp. 865-871
-
-
Tsigos, C.1
Chrousos, G.P.2
-
33
-
-
0037011958
-
P53 mutant mice that display early ageing-associated phenotypes
-
S.D. Tyner, S. Venkatachalam, J. Choi, S. Jones, N. Ghebranious, H. Igelmann, X. Lu, G. Soron, B. Cooper, C. Brayton, P.S. Hee, T. Thompson, G. Karsenty, A. Bradley, and L.A. Donehower p53 mutant mice that display early ageing-associated phenotypes Nature 2002 45 53
-
(2002)
Nature
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Igelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
Hee, P.S.11
Thompson, T.12
Karsenty, G.13
Bradley, A.14
Donehower, L.A.15
-
34
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2Sirt1
-
A. van der Horst, L.G.J. Tertoolen, L.M.M. Vries-Smits, R.A. Frye, R.H. Medema, and B.M.T. Burgering FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2Sirt1 J. Biol. Chem. 2004 28873 28879
-
(2004)
J. Biol. Chem.
, pp. 28873-28879
-
-
Van Der Horst, A.1
Tertoolen, L.G.J.2
Vries-Smits, L.M.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.T.6
-
35
-
-
0035913903
-
HSIR2(Sirt1) Functions as an NAD-dependent p53 deacetylase
-
H. Vaziri, S.K. Dessain, E.N. Eaton, S.I. Imai, R.A. Frye, T.K. Pandita, L. Guarente, and R.A. Weinberg hSIR2(Sirt1) Functions as an NAD-dependent p53 deacetylase Cell 2001 149 159
-
(2001)
Cell
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
36
-
-
0035823515
-
Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences
-
D. Yeagley, S. Guo, T. Unterman, and P.G. Quinn Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences J. Biol. Chem. 2001 33705 33710
-
(2001)
J. Biol. Chem.
, pp. 33705-33710
-
-
Yeagley, D.1
Guo, S.2
Unterman, T.3
Quinn, P.G.4
|