-
1
-
-
14744280119
-
'100 years of peptide synthesis': Ligation methods for peptide and protein synthesis with applications to β-peptide assemblies
-
DOI 10.1111/j.1399-3011.2005.00214.x
-
Kimmerlin, T.; Seebach, D. J. Pept. Res. 2005, 65, 229. doi:10.1111/j.1399-3011.2005.00214.x (Pubitemid 40327464)
-
(2005)
Journal of Peptide Research
, vol.65
, Issue.2
, pp. 229-260
-
-
Kimmerlin, T.1
Seebach, D.2
-
4
-
-
0001239683
-
-
doi:10.1351/pac199668061303
-
Goodman, M.; Shao, H. Pure Appl. Chem. 1996, 68, 1303. doi:10.1351/pac199668061303
-
(1996)
Pure Appl. Chem.
, vol.68
, pp. 1303
-
-
Goodman, M.1
Shao, H.2
-
5
-
-
0035542909
-
A field guide to foldamers
-
DOI 10.1021/cr990120t
-
Hill, D. J.; Mio, M. J.; Prince, R. B.; Hughes, T. S.; Moore, J. S. Chem. Rev. 2001, 101, 3893. doi:10.1021/cr990120t (Pubitemid 35373050)
-
(2001)
Chemical Reviews
, vol.101
, Issue.12
, pp. 3893-4011
-
-
Hill, D.J.1
Mio, M.J.2
Prince, R.B.3
Hughes, T.S.4
Moore, J.S.5
-
8
-
-
84859232982
-
-
doi:10.1002/ejoc.201101387
-
Cini, E.; Bifulco, G.; Menchi, G.; Rodriquez, M.; Taddei, M. Eur. J. Org. Chem. 2012, 2133. doi:10.1002/ejoc.201101387
-
(2012)
Eur. J. Org. Chem.
, pp. 2133
-
-
Cini, E.1
Bifulco, G.2
Menchi, G.3
Rodriquez, M.4
Taddei, M.5
-
9
-
-
0034778418
-
Solid-phase syntheses of β-turn analogues to mimic or disrupt protein - Protein interactions
-
DOI 10.1021/ar9901523
-
Burgess, K. Acc. Chem. Res. 2001, 34, 826. doi:10.1021/ar9901523 (Pubitemid 32999607)
-
(2001)
Accounts of Chemical Research
, vol.34
, Issue.10
, pp. 826-835
-
-
Burgess, K.1
-
10
-
-
60849087692
-
-
doi:10.1021/jo802052j
-
Scheffelaar, R.; Nijenhuis, R. A. K.; Paravidino, M.; Lutz, M.; Spek, A. L.; Ehlers, A. W.; de Kanter, F. J. J.; Groen, M. B.; Orru, R. V. A.; Ruijter, E. J. Org. Chem. 2009, 74, 660. doi:10.1021/jo802052j
-
(2009)
J. Org. Chem.
, vol.74
, pp. 660
-
-
Scheffelaar, R.1
Nijenhuis, R.A.K.2
Paravidino, M.3
Lutz, M.4
Spek, A.L.5
Ehlers, A.W.6
De Kanter, F.J.J.7
Groen, M.B.8
Orru, R.V.A.9
Ruijter, E.10
-
11
-
-
11844298971
-
Application of tandem Ugi multi-component reaction/ring closing metathesis to the synthesis of a conformationally restricted cyclic pentapeptide
-
DOI 10.1039/b414374d
-
Dietrich, S. A.; Banfi, L.; Basso, A.; Damonte, G.; Guanti, G.; Riva, R. Org. Biomol. Chem. 2005, 3, 97. doi:10.1039/b414374d (Pubitemid 40086166)
-
(2005)
Organic and Biomolecular Chemistry
, vol.3
, Issue.1
, pp. 97-106
-
-
Dietrich, S.A.1
Banfi, L.2
Basso, A.3
Damonte, G.4
Guanti, G.5
Riva, R.6
-
12
-
-
77949304343
-
-
doi:10.1021/jo902613j
-
Scheffelaar, R.; Paravidino, M.; Znabet, A.; Schmitz, R. F.; de Kanter, F. J. J.; Lutz, M.; Spek, A. L.; Guerra, C. F.; Bickelhaupt, F. M.; Groen, M. B.; Ruijter, E.; Orru, R. V. A. J. Org. Chem. 2010, 75, 1723. doi:10.1021/jo902613j
-
(2010)
J. Org. Chem.
, vol.75
, pp. 1723
-
-
Scheffelaar, R.1
Paravidino, M.2
Znabet, A.3
Schmitz, R.F.4
De Kanter, F.J.J.5
Lutz, M.6
Spek, A.L.7
Guerra, C.F.8
Bickelhaupt, F.M.9
Groen, M.B.10
Ruijter, E.11
Orru, R.V.A.12
-
13
-
-
37249011474
-
A convergent synthesis of enantiopure bicyclic scaffolds through multicomponent Ugi reaction
-
DOI 10.1016/j.tet.2007.10.058, PII S0040402007017929
-
Banfi, L.; Basso, A.; Guanti, G.; Merlo, S.; Repetto, C.; Riva, R. Tetrahedron 2008, 64, 1114. doi:10.1016/j.tet.2007.10.058 (Pubitemid 350266760)
-
(2008)
Tetrahedron
, vol.64
, Issue.6
, pp. 1114-1134
-
-
Banfi, L.1
Basso, A.2
Guanti, G.3
Merlo, S.4
Repetto, C.5
Riva, R.6
-
14
-
-
31544434530
-
Recent developments in isocyanide based multicomponent reactions in applied chemistry
-
DOI 10.1021/cr0505728
-
Dömling, A. Chem. Rev. 2006, 106, 17. doi:10.1021/cr0505728 (Pubitemid 43159621)
-
(2006)
Chemical Reviews
, vol.106
, Issue.1
, pp. 17-89
-
-
Domling, A.1
-
15
-
-
79959907066
-
-
doi:10.1002/anie.201006515
-
Ruijter, E.; Scheffelaar, R.; Orru, R. V. A. Angew. Chem., Int. Ed. 2011, 50, 6234. doi:10.1002/anie.201006515
-
(2011)
Angew. Chem., Int. Ed.
, vol.50
, pp. 6234
-
-
Ruijter, E.1
Scheffelaar, R.2
Orru, R.V.A.3
-
16
-
-
84868113152
-
-
doi:10.1039/c2ob26301g
-
Lesma, G.; Cecchi, R.; Crippa, S.; Giovanelli, P.; Meneghetti, F.; Musolino, M.; Sacchetti, A.; Silvani, A. Org. Biomol. Chem. 2012, 10, 9004. doi:10.1039/c2ob26301g
-
(2012)
Org. Biomol. Chem.
, vol.10
, pp. 9004
-
-
Lesma, G.1
Cecchi, R.2
Crippa, S.3
Giovanelli, P.4
Meneghetti, F.5
Musolino, M.6
Sacchetti, A.7
Silvani, A.8
-
17
-
-
0036603766
-
Recent advances in isocyanide-based multicomponent chemistry
-
DOI 10.1016/S1367-5931(02)00328-9
-
Dömling, A. Curr. Opin. Chem. Biol. 2002, 6, 306. doi:10.1016/S1367-5931(02)00328-9 (Pubitemid 34522055)
-
(2002)
Current Opinion in Chemical Biology
, vol.6
, Issue.3
, pp. 306-313
-
-
Domling, A.1
-
18
-
-
0037163321
-
Simultaneous assembly of the β-lactam and thiazole moiety by a new multicomponent reaction
-
DOI 10.1016/S0040-4039(02)01621-0, PII S0040403902016210
-
Kolb, J.; Beck, B.; Dömling, A. Tetrahedron Lett. 2002, 43, 6897. doi:10.1016/S0040-4039(02)01621-0 (Pubitemid 35246075)
-
(2002)
Tetrahedron Letters
, vol.43
, Issue.39
, pp. 6897-6901
-
-
Kolb, J.1
Beck, B.2
Domling, A.3
-
19
-
-
84862175237
-
-
doi:10.1021/cr100233r
-
Dömling, A.; Wang, W.; Wang, K. Chem. Rev. 2012, 112, 3083. doi:10.1021/cr100233r
-
(2012)
Chem. Rev.
, vol.112
, pp. 3083
-
-
Dömling, A.1
Wang, W.2
Wang, K.3
-
20
-
-
77956473421
-
-
doi:10.1021/cr900411f
-
Gulevich, A. V.; Zhdanko, A. G.; Orru, R. V. A.; Nenajdenko, V. G. Chem. Rev. 2010, 110, 5235. doi:10.1021/cr900411f
-
(2010)
Chem. Rev.
, vol.110
, pp. 5235
-
-
Gulevich, A.V.1
Zhdanko, A.G.2
Orru, R.V.A.3
Nenajdenko, V.G.4
-
21
-
-
2542509173
-
-
doi:10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.C O;2-U
-
Dömling, A.; Ugi, I. Angew. Chem., Int. Ed. 2000, 39, 3169. doi:10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.C O;2-U
-
(2000)
Angew. Chem., Int. Ed.
, vol.39
, pp. 3169
-
-
Dömling, A.1
Ugi, I.2
-
22
-
-
84890597202
-
-
Wiley-VCH: Weinheim, Germany. doi:10.1002/3527605118
-
Zhu, J.; Bienaymé, H. Multicomponent reactions; Wiley-VCH: Weinheim, Germany, 2005. doi:10.1002/3527605118
-
(2005)
Multicomponent Reactions
-
-
Zhu, J.1
Bienaymé, H.2
-
23
-
-
0345871014
-
Passerini reaction - Amine Deprotection - Acyl Migration (PADAM): A convenient strategy for the solid-phase preparation of peptidomimetic compounds
-
DOI 10.1023/B:MODI.0000006778.42751.7f
-
Banfi, L.; Basso, A.; Guanti, G.; Riva, R. Mol. Diversity 2003, 6, 227. doi:10.1023/B:MODI.0000006778.42751.7f (Pubitemid 38089860)
-
(2003)
Molecular Diversity
, vol.6
, Issue.3-4
, pp. 227-235
-
-
Banfi, L.1
Basso, A.2
Guanti, G.3
Riva, R.4
-
24
-
-
15444378113
-
Macrocycles rapidly produced by multiple multicomponent reactions including bifunctional building blocks (MiBs)
-
DOI 10.1007/s11030-005-1313-y
-
Wessjohann, L. A.; Ruijter, E. Mol. Diversity 2005, 9, 159. doi:10.1007/s11030-005-1313-y (Pubitemid 40394850)
-
(2005)
Molecular Diversity
, vol.9
, Issue.1-3
, pp. 159-169
-
-
Wessjohann, L.A.1
Ruijter, E.2
-
25
-
-
84860478728
-
-
doi:10.1039/c2cs15361k
-
de Graaff, C.; Ruijter, E.; Orru, R. V. A. Chem. Soc. Rev. 2012, 41, 3969. doi:10.1039/c2cs15361k
-
(2012)
Chem. Soc. Rev.
, vol.41
, pp. 3969
-
-
De Graaff, C.1
Ruijter, E.2
Orru, R.V.A.3
-
26
-
-
77955644148
-
Synthesis of heterocycles via multicomponent reactions i
-
Orru, R. V. A.; Ruijter, E., Eds; Springer-Verlag Berlin Heidelberg: Berlin
-
Wessjohann, L. A.; Rhoden, C. R. B.; Rivera, D. G.; Vercillo, O. E. In Synthesis of Heterocycles via Multicomponent Reactions I; Orru, R. V. A.; Ruijter, E., Eds.; Topics in Heterocyclic Chemistry, Vol. 23; Springer-Verlag Berlin Heidelberg: Berlin, 2010; pp 199-226.
-
(2010)
Topics in Heterocyclic Chemistry
, vol.23
, pp. 199-226
-
-
Wessjohann, L.A.1
Rhoden, C.R.B.2
Rivera, D.G.3
Vercillo, O.E.4
-
27
-
-
63849191356
-
-
doi:10.1021/cr8003407
-
Wessjohann, L. A.; Rivera, D. G.; Vercillo, O. E. Chem. Rev. 2009, 109, 796. doi:10.1021/cr8003407
-
(2009)
Chem. Rev.
, vol.109
, pp. 796
-
-
Wessjohann, L.A.1
Rivera, D.G.2
Vercillo, O.E.3
-
28
-
-
78649554190
-
-
doi:10.1070/RC2010v079n09ABEH004086
-
Ivachtchenko, A. V.; Ivanenkov, Y. A.; Kysil, V. M.; Krasavin, M. Y.; Ilyin, A. P. Russ. Chem. Rev. 2010, 79, 787. doi:10.1070/RC2010v079n09ABEH004086
-
(2010)
Russ. Chem. Rev.
, vol.79
, pp. 787
-
-
Ivachtchenko, A.V.1
Ivanenkov, Y.A.2
Kysil, V.M.3
Krasavin, M.Y.4
Ilyin, A.P.5
-
29
-
-
84885569717
-
Chapter 12: Applications of isocyanides in the synthesis of heterocycles
-
Nenajdenko, V. D., Ed.; Wiley-VCH: Weinheim
-
Akritopoulou-Zanze, I. Chapter 12: Applications of Isocyanides in the Synthesis of Heterocycles. In Isocyanide Chemistry; Nenajdenko, V. D., Ed.; Wiley-VCH: Weinheim, 2012; pp 451-496.
-
(2012)
Isocyanide Chemistry
, pp. 451-496
-
-
Akritopoulou-Zanze, I.1
-
30
-
-
3042709445
-
β-lactam in the new millennium. Part-I: Monobactams and carbapenems
-
DOI 10.2174/1389557043487501
-
Singh, G. S. Mini-Rev. Med. Chem. 2004, 4, 69. doi:10.2174/ 1389557043487501 (Pubitemid 38849367)
-
(2004)
Mini-Reviews in Medicinal Chemistry
, vol.4
, Issue.1
, pp. 69-92
-
-
Singh, G.S.1
-
31
-
-
0036009878
-
Efficient and highly stereoselective synthesis of a β-lactam inhibitor of the serine protease prostate-specific antigen
-
DOI 10.1016/S0968-0896(02)00017-2, PII S0968089602000172
-
Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F.; Puglisi, A. Bioorg. Med. Chem. 2002, 10, 1813. doi:10.1016/S0968-0896(02)00017-2 (Pubitemid 34286373)
-
(2002)
Bioorganic and Medicinal Chemistry
, vol.10
, Issue.6
, pp. 1813-1818
-
-
Annunziata, R.1
Benaglia, M.2
Cinquini, M.3
Cozzi, F.4
Puglisi, A.5
-
32
-
-
85047696548
-
β-lactam derivatives as enzyme inhibitors: Carboxy peptidyl derivatives of (S)-4-Oxoazetidine-2-carboxylate as peptidomimetics
-
DOI 10.1002/1521-4184(200105)334:5<167::AID-ARDP167>3.0.CO;2-O
-
Schneider, M.; Otto, H. H. Arch. Pharm. 2001, 334, 167. doi:10.1002/1521-4184(200105)334:5<167::AID-ARDP167>3.0.CO;2-O (Pubitemid 32523557)
-
(2001)
Archiv der Pharmazie
, vol.334
, Issue.5
, pp. 167-172
-
-
Schneider, M.1
Otto, H.-H.2
-
33
-
-
0034008302
-
Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones
-
DOI 10.1016/S0223-5234(00)00111-2
-
Macchia, B.; Gentili, D.; Macchia, M.; Mamone, F.; Martinelli, A.; Orlandini, E.; Rossello, A.; Cercignani, G.; Pierotti, R.; Allegretti, M.; Asti, C.; Caselli, G. Eur. J. Med. Chem. 2000, 35, 53. doi:10.1016/S0223-5234(00) 00111-2 (Pubitemid 30136688)
-
(2000)
European Journal of Medicinal Chemistry
, vol.35
, Issue.1
, pp. 53-67
-
-
MacChia, B.1
Gentili, D.2
MacChia, M.3
Mamone, F.4
Martinelli, A.5
Orlandini, E.6
Rossello, A.7
Cercignani, G.8
Pierotti, R.9
Allegretti, M.10
Asti, C.11
Caselli, G.12
-
34
-
-
0034078369
-
-
doi:10.1248/bpb.23.654
-
Saturnino, C.; Fusco, B.; Saturnino, P.; De Martino, G.; Rocco, F.; Lancelot, J.-C. Biol. Pharm. Bull. 2000, 23, 654. doi:10.1248/bpb.23.654
-
(2000)
Biol. Pharm. Bull.
, vol.23
, pp. 654
-
-
Saturnino, C.1
Fusco, B.2
Saturnino, P.3
De Martino, G.4
Rocco, F.5
Lancelot, J.-C.6
-
35
-
-
0035938401
-
Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors
-
DOI 10.1016/S0960-894X(01)00131-7, PII S0960894X01001317
-
Clemente, A.; Domingos, A.; Grancho, A. P.; Iley, J.; Moreira, R.; Neres, J.; Palma, N.; Santana, A. B.; Valente, E. Bioorg. Med. Chem. Lett. 2001, 11, 1065. doi:10.1016/S0960-894X(01)00131-7 (Pubitemid 32319982)
-
(2001)
Bioorganic and Medicinal Chemistry Letters
, vol.11
, Issue.8
, pp. 1065-1068
-
-
Clemente, A.1
Domingos, A.2
Grancho, A.P.3
Iley, J.4
Moreira, R.5
Neres, J.6
Palma, N.7
Santana, A.B.8
Valente, E.9
-
36
-
-
19944402503
-
Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease
-
DOI 10.1016/j.bmcl.2005.04.020, PII S0960894X05004804
-
Sperka, T.; Pitlik, J.; Bagossi, P.; Tözsér, J. Bioorg. Med. Chem. Lett. 2005, 15, 3086. doi:10.1016/j.bmcl.2005.04.020 (Pubitemid 40755201)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.12
, pp. 3086-3090
-
-
Sperka, T.1
Pitlik, J.2
Bagossi, P.3
Tozser, J.4
-
37
-
-
0033850289
-
-
doi:10.1002/1521-4184(20008)333:8<243::AID-ARDP243>3.0.CO;2-O
-
Achilles, K.; Schirmeister, T.; Otto, H. H. Arch. Pharm. 2000, 333, 243. doi:10.1002/1521-4184(20008)333:8<243::AID-ARDP243>3.0.CO;2-O
-
(2000)
Arch. Pharm.
, vol.333
, pp. 243
-
-
Achilles, K.1
Schirmeister, T.2
Otto, H.H.3
-
38
-
-
0030064961
-
Solid-supported combinatorial synthesis of structurally diverse β-lactams
-
DOI 10.1021/ja953322p
-
Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253. doi:10.1021/ja953322p (Pubitemid 26046881)
-
(1996)
Journal of the American Chemical Society
, vol.118
, Issue.1
, pp. 253-254
-
-
Ruhland, B.1
Bhandari, A.2
Gordon, E.M.3
Gallop, M.A.4
-
39
-
-
0037198777
-
-
doi:10.1021/ol025986r
-
Gedey, S.; Van der Eycken, J.; Fülöp, F. Org. Lett. 2002, 4, 1967. doi:10.1021/ol025986r
-
(2002)
Org. Lett.
, vol.4
, pp. 1967
-
-
Gedey, S.1
Van Der Eycken, J.2
Fülöp, F.3
-
40
-
-
34047119658
-
-
doi:10.1039/b613117d
-
Kanizsai, I.; Gyonfalvi, S.; Szakonyi, Z.; Sillanpaa, R.; Fülöp, F. Green Chem. 2007, 9, 357. doi:10.1039/b613117d
-
(2007)
Green Chem.
, vol.9
, pp. 357
-
-
Kanizsai, I.1
Gyonfalvi, S.2
Szakonyi, Z.3
Sillanpaa, R.4
Fülöp, F.5
-
42
-
-
33750963335
-
A comparative study of the multicomponent Ugi reactions of an oxabicycloheptene-based β-amino acid in water and in methanol
-
DOI 10.1016/j.tetlet.2006.10.069, PII S0040403906020806
-
Kanizsai, I.; Szakonyi, Z.; Sillanpää, R.; Fülöp, F. Tetrahedron Lett. 2006, 47, 9113. doi:10.1016/j.tetlet.2006.10.069 (Pubitemid 44738963)
-
(2006)
Tetrahedron Letters
, vol.47
, Issue.51
, pp. 9113-9116
-
-
Kanizsai, I.1
Szakonyi, Z.2
Sillanpaa, R.3
Fulop, F.4
-
43
-
-
84954358302
-
-
doi:10.1016/j.tetasy.2008.09.026
-
Szakonyi, Z.; Martinek, T. A.; Sillanpää, R.; Fülöp, F. Tetrahedron: Asymmetry 2008, 19, 2296. doi:10.1016/j.tetasy.2008.09.026
-
(2008)
Tetrahedron: Asymmetry
, vol.19
, pp. 2296
-
-
Szakonyi, Z.1
Martinek, T.A.2
Sillanpää, R.3
Fülöp, F.4
-
44
-
-
77149162419
-
-
doi:10.1007/s11030-009-9143-y
-
Szakonyi, Z.; Sillanpaa, R.; Fülöp, F. Mol. Diversity 2010, 14, 59. doi:10.1007/s11030-009-9143-y
-
(2010)
Mol. Diversity
, vol.14
, pp. 59
-
-
Szakonyi, Z.1
Sillanpaa, R.2
Fülöp, F.3
-
45
-
-
27444436849
-
Aqueous medium effects on multi-component reactions
-
DOI 10.1016/j.tet.2005.08.068, PII S004040200501464X, Multicomponent Reactions
-
Pirrung, M. C.; Das Sarma, K. Tetrahedron 2005, 61, 11456. doi:10.1016/j.tet.2005.08.068 (Pubitemid 41532313)
-
(2005)
Tetrahedron
, vol.61
, Issue.48
, pp. 11456-11472
-
-
Pirrung, M.C.1
Sarma, K.D.2
-
46
-
-
80053182993
-
-
doi:10.1016/j.tetlet.2011.08.090
-
Vishwanatha, T. M.; Narendra, N.; Sureshbabu, V. V. Tetrahedron Lett. 2011, 52, 5620. doi:10.1016/j.tetlet.2011.08.090
-
(2011)
Tetrahedron Lett.
, vol.52
, pp. 5620
-
-
Vishwanatha, T.M.1
Narendra, N.2
Sureshbabu, V.V.3
-
47
-
-
0037023466
-
2-symmetric iminosugar-based foundation
-
DOI 10.1021/jo010937y
-
Chakraborty, T. K.; Srinivasu, P.; Kumar, S. K.; Kunwar, A. C. J. Org. Chem. 2002, 67, 2093. doi:10.1021/jo010937y (Pubitemid 34292990)
-
(2002)
Journal of Organic Chemistry
, vol.67
, Issue.7
, pp. 2093-2100
-
-
Chakraborty, T.K.1
Srinivasu, P.2
Kumar, S.K.3
Kunwar, A.C.4
-
48
-
-
38149046540
-
-
doi:10.1007/s00726-007-0588-y
-
Trabocchi, A.; Scarpi, D.; Guarna, A. Amino Acids 2008, 34, 1. doi:10.1007/s00726-007-0588-y
-
(2008)
Amino Acids
, vol.34
, pp. 1
-
-
Trabocchi, A.1
Scarpi, D.2
Guarna, A.3
-
49
-
-
27744608733
-
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
-
DOI 10.1038/nature04130, PII N04130
-
Lummis, S. C. R.; Beene, D. L.; Lee, L. W.; Lester, H. A.; Broadhurst, R. W.; Dougherty, D. A. Nature 2005, 438, 248. doi:10.1038/nature04130 (Pubitemid 41599879)
-
(2005)
Nature
, vol.438
, Issue.7065
, pp. 248-252
-
-
Lummis, S.C.R.1
Beene, D.L.2
Lee, L.W.3
Lester, H.A.4
Broadhurst, R.W.5
Dougherty, D.A.6
-
50
-
-
0035914012
-
Influence of chirality of the preceding acyl moiety on the cis/trans ratio of the proline peptide bond
-
DOI 10.1021/jo0159439
-
Breznik, M.; Grdadolnik, S. G.; Giester, G.; Leban, I.; Kikelj, D. J. Org. Chem. 2001, 66, 7044. doi:10.1021/jo0159439 (Pubitemid 32983089)
-
(2001)
Journal of Organic Chemistry
, vol.66
, Issue.21
, pp. 7044-7050
-
-
Breznik, M.1
Grdadolnik, S.G.2
Giester, G.3
Leban, I.4
Kikelj, D.5
-
51
-
-
39349099756
-
N2′ cyclizations
-
DOI 10.1021/jo702087x
-
Banfi, L.; Basso, A.; Cerulli, V.; Guanti, G.; Riva, R. J. Org. Chem. 2008, 73, 1608. doi:10.1021/jo702087x (Pubitemid 351263686)
-
(2008)
Journal of Organic Chemistry
, vol.73
, Issue.4
, pp. 1608-1611
-
-
Banfi, L.1
Basso, A.2
Cerulli, V.3
Guanti, G.4
Riva, R.5
-
52
-
-
3943095914
-
-
doi:10.1055/s-2004-829085
-
Hara, O.; Sugimoto, K.; Makino, K.; Hamada, Y. Synlett 2004, 1625. doi:10.1055/s-2004-829085
-
(2004)
Synlett
, vol.1625
-
-
Hara, O.1
Sugimoto, K.2
Makino, K.3
Hamada, Y.4
-
53
-
-
33646562788
-
The Ugi reaction with 2-substituted cyclic imines. Synthesis of substituted proline and homoproline derivatives
-
DOI 10.1016/j.tet.2006.04.021, PII S0040402006006181
-
Nenajdenko, V. G.; Gulevich, A. V.; Balenkova, E. S. Tetrahedron 2006, 62, 5922. doi:10.1016/j.tet.2006.04.021 (Pubitemid 43728082)
-
(2006)
Tetrahedron
, vol.62
, Issue.25
, pp. 5922-5930
-
-
Nenajdenko, V.G.1
Gulevich, A.V.2
Balenkova, E.S.3
-
54
-
-
0000660206
-
-
doi:10.1021/jo00298a062
-
Hua, D. H.; Miao, S. W.; Bharathi, S. N.; Katsuhira, T.; Bravo, A. A. J. Org. Chem. 1990, 55, 3682. doi:10.1021/jo00298a062
-
(1990)
J. Org. Chem.
, vol.55
, pp. 3682
-
-
Hua, D.H.1
Miao, S.W.2
Bharathi, S.N.3
Katsuhira, T.4
Bravo, A.A.5
-
55
-
-
4143068053
-
Enantio- and diastereoselective synthesis of 2,5-disubstituted pyrrolidines through a multicomponent Ugi reaction and their transformation into bicyclic scaffolds
-
DOI 10.1016/j.tetlet.2004.07.015, PII S0040403904014753
-
Banfi, L.; Basso, A.; Guanti, G.; Riva, R. Tetrahedron Lett. 2004, 45, 6637. doi:10.1016/j.tetlet.2004.07.015 (Pubitemid 39091872)
-
(2004)
Tetrahedron Letters
, vol.45
, Issue.35
, pp. 6637-6640
-
-
Banfi, L.1
Basso, A.2
Guanti, G.3
Riva, R.4
-
56
-
-
0034675243
-
-
doi:10.1016/S0040-4039(00)01266-1
-
Schlemminger, I.; Janknecht, H.-H.; Maison, W.; Saak, W.; Martens, J. Tetrahedron Lett. 2000, 41, 7289. doi:10.1016/S0040-4039(00)01266-1
-
(2000)
Tetrahedron Lett.
, vol.41
, pp. 7289
-
-
Schlemminger, I.1
Janknecht, H.-H.2
Maison, W.3
Saak, W.4
Martens, J.5
-
57
-
-
0039150859
-
First catalytic asymmetric hydrophosphonylation of cyclic imines: Highly efficient enantioselective approach to a 4-thiazolidinylphosphonate via chiral titanium and lanthanoid catalysts
-
DOI 10.1016/S0040-4039(97)82944-9, PII S0040403996021831
-
Gröger, H.; Saida, Y.; Arai, S.; Martens, J.; Sasai, H.; Shibasaki, M. Tetrahedron Lett. 1996, 37, 9291. doi:10.1016/S0040-4039(97)82944-9 (Pubitemid 26421944)
-
(1996)
Tetrahedron Letters
, vol.37
, Issue.52
, pp. 9291-9292
-
-
Groger, H.1
Saida, Y.2
Arai, S.3
Martens, J.4
Sasai, H.5
Shibasaki, M.6
-
58
-
-
12944279761
-
Glyco- and peptidomimetics from three-component joullié-ugi coupling show selective antiviral activity
-
DOI 10.1021/ja043924l
-
Chapman, T. M.; Davies, I. G.; Gu, B.; Block, T. M.; Scopes, D. I. C.; Hay, P. A.; Courtney, S. M.; McNeill, L. A.; Schofield, C. J.; Davis, B. G. J. Am. Chem. Soc. 2005, 127, 506. doi:10.1021/ja043924l (Pubitemid 40174360)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.2
, pp. 506-507
-
-
Chapman, T.M.1
Davies, I.G.2
Gu, B.3
Block, T.M.4
Scopes, D.I.C.5
Hay, P.A.6
Courtney, S.M.7
McNeill, L.A.8
Schofield, C.J.9
Davis, B.G.10
-
59
-
-
84864984658
-
-
doi:10.1002/adsc.201200140
-
Morana, F.; Basso, A.; Bella, M.; Riva, R.; Banfi, L. Adv. Synth. Catal. 2012, 354, 2199. doi:10.1002/adsc.201200140
-
(2012)
Adv. Synth. Catal.
, vol.354
, pp. 2199
-
-
Morana, F.1
Basso, A.2
Bella, M.3
Riva, R.4
Banfi, L.5
-
60
-
-
84856155925
-
-
doi:10.1039/c1ob06632c
-
Cerulli, V.; Banfi, L.; Basso, A.; Rocca, V.; Riva, R. Org. Biomol. Chem. 2012, 10, 1255. doi:10.1039/c1ob06632c
-
(2012)
Org. Biomol. Chem.
, vol.10
, pp. 1255
-
-
Cerulli, V.1
Banfi, L.2
Basso, A.3
Rocca, V.4
Riva, R.5
-
61
-
-
77954844157
-
-
doi:10.1002/anie.201001592
-
Znabet, A.; Ruijter, E.; de Kanter, F. J. J.; Kohler, V.; Helliwell, M.; Turner, N. J.; Orru, R. V. A. Angew. Chem., Int. Ed. 2010, 49, 5289. doi:10.1002/anie.201001592
-
(2010)
Angew. Chem., Int. Ed.
, vol.49
, pp. 5289
-
-
Znabet, A.1
Ruijter, E.2
De Kanter, F.J.J.3
Kohler, V.4
Helliwell, M.5
Turner, N.J.6
Orru, R.V.A.7
-
62
-
-
77949355247
-
-
doi:10.1002/anie.200906655
-
Köhler, V.; Bailey, K. R.; Znabet, A.; Raftery, J.; Helliwell, M.; Turner, N. J. Angew. Chem., Int. Ed. 2010, 49, 2182. doi:10.1002/anie.200906655
-
(2010)
Angew. Chem., Int. Ed.
, vol.49
, pp. 2182
-
-
Köhler, V.1
Bailey, K.R.2
Znabet, A.3
Raftery, J.4
Helliwell, M.5
Turner, N.J.6
-
63
-
-
77958485628
-
-
doi:10.1039/c0cc02823a
-
Znabet, A.; Polak, M. M.; Janssen, E.; de Kanter, F. J. J.; Turner, N. J.; Orru, R. V. A.; Ruijter, E. Chem. Commun. 2010, 46, 7918. doi:10.1039/c0cc02823a
-
(2010)
Chem. Commun.
, vol.46
, pp. 7918
-
-
Znabet, A.1
Polak, M.M.2
Janssen, E.3
De Kanter, F.J.J.4
Turner, N.J.5
Orru, R.V.A.6
Ruijter, E.7
-
64
-
-
0019163001
-
-
doi:10.1126/science.7001627
-
Freidinger, R. M.; Veber, D. F.; Perlow, D. S.; Brooks, J. R.; Saperstein, R. Science 1980, 210, 656. doi:10.1126/science.7001627
-
(1980)
Science
, vol.210
, pp. 656
-
-
Freidinger, R.M.1
Veber, D.F.2
Perlow, D.S.3
Brooks, J.R.4
Saperstein, R.5
-
65
-
-
0029882080
-
3,3-Dialkyl- and 3-alkyl-3-benzyl-substituted 2-pyrrolidinones: A new class of anticonvulsant agents
-
DOI 10.1021/jm9600196
-
Reddy, P. A.; Hsiang, B. C. H.; Latifi, T. N.; Hill, M. W.; Woodward, K. E.; Rothman, S. M.; Ferrendelli, J. A.; Covey, D. F. J. Med. Chem. 1996, 39, 1898. doi:10.1021/jm9600196 (Pubitemid 26142829)
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.9
, pp. 1898-1906
-
-
Reddy, P.A.1
Hsiang, B.C.H.2
Latifi, T.N.3
Hill, M.W.4
Woodward, K.E.5
Rothman, S.M.6
Ferrendelli, J.A.7
Covey, D.F.8
-
66
-
-
33748357081
-
-
doi:10.1002/ejoc.200600153
-
Das Sarma, K.; Zhang, J.; Huang, Y.; Davidson, J. G. Eur. J. Org. Chem. 2006, 3730. doi:10.1002/ejoc.200600153
-
(2006)
Eur. J. Org. Chem.
, pp. 3730
-
-
Das Sarma, K.1
Zhang, J.2
Huang, Y.3
Davidson, J.G.4
-
67
-
-
0034608468
-
Novel inhibitors of HIV protease: Design, synthesis and biological evaluation of picomolar inhibitors containing cyclic P1/P2 scaffolds
-
DOI 10.1016/S0960-894X(00)00163-3, PII S0960894X00001633
-
Spaltenstein, A.; Almond, M. R.; Bock, W. J.; Cleary, D. G.; Furfine, E. S.; Hazen, R. J.; Kazmierski, W. M.; Salituro, F. G.; Tung, R. D.; Wright, L. L. Bioorg. Med. Chem. Lett. 2000, 10, 1159. doi:10.1016/S0960-894X(00)00163-3 (Pubitemid 30345081)
-
(2000)
Bioorganic and Medicinal Chemistry Letters
, vol.10
, Issue.11
, pp. 1159-1162
-
-
Spaltenstein, A.1
Almond, M.R.2
Bock, W.J.3
Cleary, D.G.4
Furfine, E.S.5
Hazen, R.J.6
Kazmierski, W.M.7
Salituro, F.G.8
Tung, R.D.9
Wright, L.L.10
-
68
-
-
5144222589
-
Discovery of potent pyrrolidone-based HIV-1 protease inhibitors with enhanced drug-like properties
-
DOI 10.1016/j.bmcl.2004.08.039, PII S0960894X04010479
-
Kazmierski, W. M.; Andrews, W.; Furfine, E.; Spaltenstein, A.; Wright, L. Bioorg. Med. Chem. Lett. 2004, 14, 5689. doi:10.1016/j.bmcl.2004.08.039 (Pubitemid 39346370)
-
(2004)
Bioorganic and Medicinal Chemistry Letters
, vol.14
, Issue.22
, pp. 5689-5692
-
-
Kazmierski, W.M.1
Andrews, W.2
Furfine, E.3
Spaltenstein, A.4
Wright, L.5
-
69
-
-
0037032313
-
Development of a catalytic enantioselective conjugate addition of 1,3-dicarbonyl compounds to nitroalkenes for the synthesis of endothelin-A antagonist ABT-546. Scope, mechanism, and further application to the synthesis of the antidepressant rolipram
-
DOI 10.1021/ja026788y
-
Barnes, D. M.; Ji, J. G.; Fickes, M. G.; Fitzgerald, M. A.; King, S. A.; Morton, H. E.; Plagge, F. A.; Preskill, M.; Wagaw, S. H.; Wittenberger, S. J.; Zhang, J. J. Am. Chem. Soc. 2002, 124, 13097. doi:10.1021/ja026788y (Pubitemid 35247122)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.44
, pp. 13097-13105
-
-
Barnes, D.M.1
Ji, J.2
Fickes, M.G.3
Fitzgerald, M.A.4
King, S.A.5
Morton, H.E.6
Plagge, F.A.7
Preskill, M.8
Wagaw, S.H.9
Wittenberger, S.J.10
Zhang, J.11
-
70
-
-
0032580388
-
Multi-component reactions 13: Synthesis of γ-lactams as part of a multi-ring system via Ugi-4-centre-3-component reaction
-
DOI 10.1016/S0040-4039(98)00428-6, PII S0040403998004286
-
Hanusch-Kompa, C.; Ugi, I. Tetrahedron Lett. 1998, 39, 2725. doi:10.1016/S0040-4039(98)00428-6 (Pubitemid 28186661)
-
(1998)
Tetrahedron Letters
, vol.39
, Issue.18
, pp. 2725-2728
-
-
Hanusch-Kompa, C.1
Ugi, I.2
-
71
-
-
0031022868
-
A solid-phase combinatorial method for the synthesis of novel 5- and 6-membered ring lactams
-
DOI 10.1016/S0040-4039(96)02303-9, PII S0040403996023039
-
Short, K. M.; Mjalli, A. M. M. Tetrahedron Lett. 1997, 38, 359. doi:10.1016/S0040-4039(96)02303-9 (Pubitemid 27034063)
-
(1997)
Tetrahedron Letters
, vol.38
, Issue.3
, pp. 359-362
-
-
Short, K.M.1
Mjalli, A.M.2
-
72
-
-
0030873527
-
Synthesis of small and medium sized 2,2-disubstituted lactams via the 'intramolecular' three component Ugi reaction
-
DOI 10.1016/S0040-4039(97)01265-3, PII S0040403997012653
-
Harriman, G. C. B. Tetrahedron Lett. 1997, 38, 5591. doi:10.1016/S0040- 4039(97)01265-3 (Pubitemid 27321130)
-
(1997)
Tetrahedron Letters
, vol.38
, Issue.32
, pp. 5591-5594
-
-
Harriman, G.C.B.1
-
73
-
-
0034681853
-
Novel applications of convertible isonitriles for the synthesis of mono and bicyclic γ-lactams via a UDC strategy
-
DOI 10.1016/S0040-4039(00)00052-6, PII S0040403900000526
-
Hulme, C.; Ma, L.; Cherrier, M.-P.; Romano, J. J.; Morton, G.; Duquenne, C.; Salvino, J.; Labaudiniere, R. Tetrahedron Lett. 2000, 41, 1883. doi:10.1016/S0040-4039(00)00052-6 (Pubitemid 30167307)
-
(2000)
Tetrahedron Letters
, vol.41
, Issue.12
, pp. 1883-1887
-
-
Hulme, C.1
Ma, L.2
Cherrier, M.-P.3
Romano, J.J.4
Morton, G.5
Duquenne, C.6
Salvino, J.7
Labaudiniere, R.8
-
74
-
-
3142683044
-
Preparation of peptide-like bicyclic lactams via a sequential Ugi reaction - Olefin metathesis approach
-
DOI 10.1016/j.tetlet.2004.06.052, PII S0040403904013097
-
Krelaus, R.; Westermann, B. Tetrahedron Lett. 2004, 45, 5987. doi:10.1016/j.tetlet.2004.06.052 (Pubitemid 38916539)
-
(2004)
Tetrahedron Letters
, vol.45
, Issue.31
, pp. 5987-5990
-
-
Krelaus, R.1
Westermann, B.2
-
75
-
-
3142683132
-
-
doi:10.1002/chem.200305581
-
Ma, S.; Ni, B. Chem.-Eur. J. 2004, 10, 3286. doi:10.1002/chem.200305581
-
(2004)
Chem.-Eur. J.
, vol.10
, pp. 3286
-
-
Ma, S.1
Ni, B.2
-
76
-
-
0000218515
-
-
doi:10.1021/ol0172673
-
Ma, S.; Ni, B. Org. Lett. 2002, 4, 639. doi:10.1021/ol0172673
-
(2002)
Org. Lett.
, vol.4
, pp. 639
-
-
Ma, S.1
Ni, B.2
-
77
-
-
77949811753
-
-
doi:10.1021/ol1001208
-
Miller, N.; Williams, G. M.; Brimble, M. A. Org. Lett. 2010, 12, 1375. doi:10.1021/ol1001208
-
(2010)
Org. Lett.
, vol.12
, pp. 1375
-
-
Miller, N.1
Williams, G.M.2
Brimble, M.A.3
-
78
-
-
33749989262
-
A potentially valuable advance in the synthesis of carbohydrate-based anticancer vaccines through extended cycloaddition chemistry
-
DOI 10.1021/jo061406i
-
Wan, Q.; Chen, J.; Chen, G.; Danishefsky, S. J. J. Org. Chem. 2006, 71, 8244. doi:10.1021/jo061406i (Pubitemid 44571835)
-
(2006)
Journal of Organic Chemistry
, vol.71
, Issue.21
, pp. 8244-8249
-
-
Wan, Q.1
Chen, J.2
Chen, G.3
Danishefsky, S.J.4
-
79
-
-
0037012920
-
Peptidotriazoles on solid phase: [1,2,3]-Triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
-
DOI 10.1021/jo011148j
-
Tornoe, C. W.; Christensen, C.; Meldal, M. J. Org. Chem. 2002, 67, 3057. doi:10.1021/jo011148j (Pubitemid 34457265)
-
(2002)
Journal of Organic Chemistry
, vol.67
, Issue.9
, pp. 3057-3064
-
-
Tornoe, C.W.1
Christensen, C.2
Meldal, M.3
-
80
-
-
33845939348
-
Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization
-
DOI 10.1021/jm060754+
-
Whiting, M.; Tripp, J. C.; Lin, Y.-C.; Lindstrom, W.; Olson, A. J.; Elder, J. H.; Sharpless, K. B.; Fokin, V. V. J. Med. Chem. 2006, 49, 7697. doi:10.1021/jm060754+ (Pubitemid 46033661)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.26
, pp. 7697-7710
-
-
Whiting, M.1
Tripp, J.C.2
Lin, Y.-C.3
Lindstrom, W.4
Olson, A.J.5
Elder, J.H.6
Sharpless, K.B.7
Fokin, V.V.8
-
83
-
-
37349065872
-
The 1,2,3-triazole ring as a peptido- and olefinomimetic element: Discovery of click yanilloids and cannabinoids
-
DOI 10.1002/anie.200703590
-
Appendino, G.; Bacchiega, S.; Minassi, A.; Cascio, M. G.; De Petrocellis, L.; Di Marzo, V. Angew. Chem., Int. Ed. 2007, 46, 9312. doi:10.1002/anie. 200703590 (Pubitemid 350292167)
-
(2007)
Angewandte Chemie - International Edition
, vol.46
, Issue.48
, pp. 9312-9315
-
-
Appendino, G.1
Bacchiega, S.2
Minassi, A.3
Cascio, M.G.4
De Petrocellis, L.5
Di Marzo, V.6
-
84
-
-
0348109450
-
The growing impact of click chemistry on drug discovery
-
DOI 10.1016/S1359-6446(03)02933-7, PII S1359644603029337
-
Kolb, H. C.; Sharpless, K. B. Drug Discovery Today 2003, 8, 1128. doi:10.1016/S1359-6446(03)02933-7 (Pubitemid 37547919)
-
(2003)
Drug Discovery Today
, vol.8
, Issue.24
, pp. 1128-1137
-
-
Kolb, H.C.1
Sharpless, K.B.2
-
85
-
-
77649199080
-
-
doi:10.1002/ejoc.200901326
-
Nenajdenko, V. G.; Gulevich, A. V.; Sokolova, N. V.; Mironov, A. V.; Balenkova, E. S. Eur. J. Org. Chem. 2010, 1445. doi:10.1002/ejoc.200901326
-
(2010)
Eur. J. Org. Chem.
, pp. 1445
-
-
Nenajdenko, V.G.1
Gulevich, A.V.2
Sokolova, N.V.3
Mironov, A.V.4
Balenkova, E.S.5
-
86
-
-
83555165158
-
-
doi:10.1016/j.tet.2011.11.037
-
Vorobyeva, D. V.; Sokolova, N. V.; Nenajdenko, V. G.; Peregudov, A. S.; Osipov, S. N. Tetrahedron 2012, 68, 872. doi:10.1016/j.tet.2011.11.037
-
(2012)
Tetrahedron
, vol.68
, pp. 872
-
-
Vorobyeva, D.V.1
Sokolova, N.V.2
Nenajdenko, V.G.3
Peregudov, A.S.4
Osipov, S.N.5
-
87
-
-
0037071153
-
Synthesis and thermodynamic characterization of self-sorting coiled coils
-
DOI 10.1016/S0040-4020(02)00260-0, PII S0040402002002600
-
Bilgicer, B.; Kumar, K. Tetrahedron 2002, 58, 4105. doi:10.1016/S0040- 4020(02)00260-0 (Pubitemid 34465683)
-
(2002)
Tetrahedron
, vol.58
, Issue.20
, pp. 4105-4112
-
-
Bilgicer, B.1
Kumar, K.2
-
88
-
-
27944467415
-
Computer-aided analysis and design of phosphonic and phosphinic enzyme inhibitors as potential drugs and agrochemicals
-
DOI 10.2174/138527205774913088
-
Berlicki, L.; Kafarski, P. Curr. Org. Chem. 2005, 9, 1829. doi:10.2174/138527205774913088 (Pubitemid 41672457)
-
(2005)
Current Organic Chemistry
, vol.9
, Issue.18
, pp. 1829-1850
-
-
Berlicki, L.1
Kafarski, P.2
-
89
-
-
76549090674
-
-
doi:10.1016/j.jfluchem.2009.12.003
-
Vorobyeva, D. V.; Karimova, N. M.; Vasilyeva, T. P.; Osipov, S. N.; Shchetnikov, G. T.; Odinets, I. L.; Röschenthaler, G.-V. J. Fluorine Chem. 2010, 131, 378. doi:10.1016/j.jfluchem.2009.12.003
-
(2010)
J. Fluorine Chem.
, vol.131
, pp. 378
-
-
Vorobyeva, D.V.1
Karimova, N.M.2
Vasilyeva, T.P.3
Osipov, S.N.4
Shchetnikov, G.T.5
Odinets, I.L.6
Röschenthaler, G.-V.7
-
90
-
-
77649197528
-
-
doi:10.1002/ejoc.200901354
-
Shchetnikov, G. T.; Zotova, M. A.; Bruneau, C.; Dixneuf, P. H.; Osipov, S. N. Eur. J. Org. Chem. 2010, 1587. doi:10.1002/ejoc.200901354
-
(2010)
Eur. J. Org. Chem.
, pp. 1587
-
-
Shchetnikov, G.T.1
Zotova, M.A.2
Bruneau, C.3
Dixneuf, P.H.4
Osipov, S.N.5
-
92
-
-
84856015469
-
-
doi:10.1002/hlca.201100253
-
Niu, T.-F.; Cai, C.; Yi, L. Helv. Chim. Acta 2012, 95, 87. doi:10.1002/hlca.201100253
-
(2012)
Helv. Chim. Acta
, vol.95
, pp. 87
-
-
Niu, T.-F.1
Cai, C.2
Yi, L.3
-
93
-
-
84863767871
-
-
doi:10.1021/co300061p
-
Niu, T.-F.; Gu, L.; Yi, W.-b.; Cai, C. ACS Comb. Sci. 2012, 14, 442. doi:10.1021/co300061p
-
(2012)
ACS Comb. Sci.
, vol.14
, pp. 442
-
-
Niu, T.-F.1
Gu, L.2
Yi, W.-B.3
Cai, C.4
-
95
-
-
22844443265
-
Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives
-
DOI 10.1016/j.bmcl.2005.05.055, PII S0960894X0500675X, G-Protein Coupled Receptors in Drug Discovery
-
Cui, Y.-M.; Huang, Q.-Q.; Xu, J.; Chen, L.-L.; Li, J.-Y.; Ye, Q.-Z.; Li, J.; Nan, F.-J. Bioorg. Med. Chem. Lett. 2005, 15, 3732. doi:10.1016/j.bmcl.2005. 05.055 (Pubitemid 41038968)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.16
, pp. 3732-3736
-
-
Cui, Y.-M.1
Huang, Q.-Q.2
Xu, J.3
Chen, L.-L.4
Li, J.-Y.5
Ye, Q.-Z.6
Li, J.7
Nan, F.-J.8
-
97
-
-
37249089097
-
Bacillamides from a hypersaline microbial mat bacterium
-
DOI 10.1021/np070126a
-
Socha, A. M.; Long, R. A.; Rowley, D. C. J. Nat. Prod. 2007, 70, 1793. doi:10.1021/np070126a (Pubitemid 350275538)
-
(2007)
Journal of Natural Products
, vol.70
, Issue.11
, pp. 1793-1795
-
-
Socha, A.M.1
Long, R.A.2
Rowley, D.C.3
-
98
-
-
0025820445
-
-
doi:10.1021/jm00109a011
-
Marsham, P. R.; Hughes, L. R.; Jackman, A. L.; Hayter, A. J.; Oldfield, J.; Wardleworth, J. M.; Bishop, J. A. M.; Oconnor, B. M.; Calvert, A. H. J. Med. Chem. 1991, 34, 1594. doi:10.1021/jm00109a011
-
(1991)
J. Med. Chem.
, vol.34
, pp. 1594
-
-
Marsham, P.R.1
Hughes, L.R.2
Jackman, A.L.3
Hayter, A.J.4
Oldfield, J.5
Wardleworth, J.M.6
Bishop, J.A.M.7
Oconnor, B.M.8
Calvert, A.H.9
-
99
-
-
0023584049
-
-
doi:10.1021/ja00256a070
-
Pettit, G. R.; Kamano, Y.; Herald, C. L.; Tuinman, A. A.; Boettner, F. E.; Kizu, H.; Schmidt, J. M.; Baczynskyj, L.; Tomer, K. B.; Bontems, R. J. J. Am. Chem. Soc. 1987, 109, 6883. doi:10.1021/ja00256a070
-
(1987)
J. Am. Chem. Soc.
, vol.109
, pp. 6883
-
-
Pettit, G.R.1
Kamano, Y.2
Herald, C.L.3
Tuinman, A.A.4
Boettner, F.E.5
Kizu, H.6
Schmidt, J.M.7
Baczynskyj, L.8
Tomer, K.B.9
Bontems, R.J.10
-
100
-
-
33947614011
-
Library synthesis and screening: 2,4-Diphenylthiazoles and 2,4-diphenyloxazoles as potential novel prion disease therapeutics
-
DOI 10.1021/jm0612719
-
Heal, W.; Thompson, M. J.; Mutter, R.; Cope, H.; Louth, J. C.; Chen, B. J. Med. Chem. 2007, 50, 1347. doi:10.1021/jm0612719 (Pubitemid 46496333)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.6
, pp. 1347-1353
-
-
Heal, W.1
Thompson, M.J.2
Mutter, R.3
Cope, H.4
Louth, J.C.5
Chen, B.6
-
101
-
-
0345871007
-
New MCRs: The first 4-component reaction leading to 2,4-disubstituted thiazoles
-
DOI 10.1023/B:MODI.0000006827.35029.e4
-
Kolb, J.; Beck, B.; Almstetter, M.; Heck, S.; Herdtweck, E.; Dömling, A. Mol. Diversity 2003, 6, 297. doi:10.1023/B:MODI.0000006827. 35029.e4 (Pubitemid 38089868)
-
(2003)
Molecular Diversity
, vol.6
, Issue.3-4
, pp. 297-313
-
-
Kolb, J.1
Beck, B.2
Almstetter, M.3
Heck, S.4
Herdtweck, E.5
Domling, A.6
-
102
-
-
0039944586
-
-
doi:10.1055/s-2000-6517
-
Heck, S.; Dömling, A. Synlett 2000, 424. doi:10.1055/s-2000-6517
-
(2000)
Synlett
, pp. 424
-
-
Heck, S.1
Dömling, A.2
-
104
-
-
0037471469
-
A new and efficient multicomponent solid-phase synthesis of 2-acylaminomethylthiazoles
-
DOI 10.1016/S0040-4039(03)00662-2
-
Henkel, B.; Sax, M.; Dömling, A. Tetrahedron Lett. 2003, 44, 3679. doi:10.1016/S0040-4039(03)00662-2 (Pubitemid 36419594)
-
(2003)
Tetrahedron Letters
, vol.44
, Issue.18
, pp. 3679-3682
-
-
Henkel, B.1
Sax, M.2
Domling, A.3
-
105
-
-
0005163750
-
-
doi:10.1002/cber.19540870806
-
Wieland, T.; Freter, K. Chem. Ber. 1954, 87, 1099. doi:10.1002/cber. 19540870806
-
(1954)
Chem. Ber.
, vol.87
, pp. 1099
-
-
Wieland, T.1
Freter, K.2
-
106
-
-
47549085325
-
-
doi:10.1016/j.tetlet.2008.06.067
-
Thompson, M. J.; Chen, B. Tetrahedron Lett. 2008, 49, 5324. doi:10.1016/j.tetlet.2008.06.067
-
(2008)
Tetrahedron Lett.
, vol.49
, pp. 5324
-
-
Thompson, M.J.1
Chen, B.2
-
109
-
-
75149172694
-
-
doi:10.1039/b918214d
-
Wang, W.; Joyner, S.; Khoury, K. A. S.; Dömling, A. Org. Biomol. Chem. 2010, 8, 529. doi:10.1039/b918214d
-
(2010)
Org. Biomol. Chem.
, vol.8
, pp. 529
-
-
Wang, W.1
Joyner, S.2
Khoury, K.A.S.3
Dömling, A.4
-
110
-
-
0001419996
-
A novel multicomponent synthesis of polysubstituted 5-aminooxazole and its new scaffold-generating reaction to pyrrolo[3,4-b]pyridine
-
DOI 10.1021/ol007055q
-
Sun, X.; Janvier, P.; Zhao, G.; Bienaymé, H.; Zhu, J. Org. Lett. 2001, 3, 877. doi:10.1021/ol007055q (Pubitemid 33629416)
-
(2001)
Organic Letters
, vol.3
, Issue.6
, pp. 877-880
-
-
Sun, X.1
Janvier, P.2
Zhao, G.3
Bienayme, H.4
Zhu, J.5
-
111
-
-
0037139571
-
Ammonium chloride-promoted four-component synthesis of pyrrolo[3,4-b] pyridin-5-one
-
DOI 10.1021/ja017563a
-
Janvier, P.; Sun, X.; Bienaymé, H.; Zhu, J. J. Am. Chem. Soc. 2002, 124, 2560. doi:10.1021/ja017563a (Pubitemid 34251770)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.11
, pp. 2560-2567
-
-
Janvier, P.1
Sun, X.2
Bienayme, H.3
Zhu, J.4
-
112
-
-
11444270603
-
Ammonium chloride promoted Ugi four-component, five-center reaction of α-substituted α-isocyano acetic acid: A strong solvent effect
-
DOI 10.1021/ol0479388
-
Bonne, D.; Dekhane, M.; Zhu, J. Org. Lett. 2004, 6, 4771. doi:10.1021/ol0479388 (Pubitemid 40081641)
-
(2004)
Organic Letters
, vol.6
, Issue.25
, pp. 4771-4774
-
-
Bonne, D.1
Dekhane, M.2
Zhu, J.3
-
113
-
-
84862776950
-
-
doi:10.1016/j.tetlet.2012.02.030
-
Shaw, A. Y.; Xu, Z.; Hulme, C. Tetrahedron Lett. 2012, 53, 1998. doi:10.1016/j.tetlet.2012.02.030
-
(2012)
Tetrahedron Lett.
, vol.53
, pp. 1998
-
-
Shaw, A.Y.1
Xu, Z.2
Hulme, C.3
-
114
-
-
37849000897
-
-
doi:10.1021/jm7010595
-
Li, J.; Chen, S. Y.; Li, J. J.; Wang, H.; Hernandez, A. S.; Tao, S.; Musial, C. M.; Qu, F.; Swartz, S.; Chao, S. T.; Flynn, N.; Murphy, B. J.; Slusarchyk, D. A.; Seethala, R.; Yan, M.; Sleph, P.; Grover, G.; Smith, M. A.; Beehler, B.; Giupponi, L.; Dickinson, K. E.; Zhang, H.; Humphreys, W. G.; Patel, B. P.; Schwinden, M.; Stouch, T.; Cheng, P. T. W.; Biller, S. A.; Ewing, W. R.; Gordon, D.; Robl, J. A.; Tino, J. A. J. Med. Chem. 2007, 50, 5890. doi:10.1021/jm7010595
-
(2007)
J. Med. Chem.
, vol.50
, pp. 5890
-
-
Li, J.1
Chen, S.Y.2
Li, J.J.3
Wang, H.4
Hernandez, A.S.5
Tao, S.6
Musial, C.M.7
Qu, F.8
Swartz, S.9
Chao, S.T.10
Flynn, N.11
Murphy, B.J.12
Slusarchyk, D.A.13
Seethala, R.14
Yan, M.15
Sleph, P.16
Grover, G.17
Smith, M.A.18
Beehler, B.19
Giupponi, L.20
Dickinson, K.E.21
Zhang, H.22
Humphreys, W.G.23
Patel, B.P.24
Schwinden, M.25
Stouch, T.26
Cheng, P.T.W.27
Biller, S.A.28
Ewing, W.R.29
Gordon, D.30
Robl, J.A.31
Tino, J.A.32
more..
-
115
-
-
0001432279
-
-
doi:10.1021/ja00225a045
-
Zabrocki, J.; Smith, G. D.; Dunbar, J. B.; Iijima, H.; Marshall, G. R. J. Am. Chem. Soc. 1988, 110, 5875. doi:10.1021/ja00225a045
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 5875
-
-
Zabrocki, J.1
Smith, G.D.2
Dunbar, J.B.3
Iijima, H.4
Marshall, G.R.5
-
116
-
-
79952364144
-
-
doi:10.1016/j.bmcl.2011.01.057
-
Al-Hourani, B. J.; Sharma, S. K.; Mane, J. Y.; Tuszynski, J.; Baracos, V.; Kniess, T.; Suresh, M.; Pietzsch, J.; Wuest, F. Bioorg. Med. Chem. Lett. 2011, 21, 1823. doi:10.1016/j.bmcl.2011.01.057
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 1823
-
-
Al-Hourani, B.J.1
Sharma, S.K.2
Mane, J.Y.3
Tuszynski, J.4
Baracos, V.5
Kniess, T.6
Suresh, M.7
Pietzsch, J.8
Wuest, F.9
-
117
-
-
0037997042
-
-
Johansson, A.; Poliakov, A.; Akerblom, E.; Wiklund, K.; Lindeberg, G.; Winiwarter, S.; Danielson, U. H.; Samuelsson, B.; Hallberg, A. Bioorg. Med. Chem. Lett. 2003, 11, 2551.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 2551
-
-
Johansson, A.1
Poliakov, A.2
Akerblom, E.3
Wiklund, K.4
Lindeberg, G.5
Winiwarter, S.6
Danielson, U.H.7
Samuelsson, B.8
Hallberg, A.9
-
118
-
-
33746605204
-
The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases
-
DOI 10.1021/ja062999h
-
Alexander, J. P.; Cravatt, B. F. J. Am. Chem. Soc. 2006, 128, 9699. doi:10.1021/ja062999h (Pubitemid 44147953)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.30
, pp. 9699-9704
-
-
Alexander, J.P.1
Cravatt, B.F.2
-
119
-
-
41149148300
-
Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonists
-
DOI 10.1016/j.bmcl.2008.02.061, PII S0960894X08002424
-
Kang, S. Y.; Lee, S.; Seo, H. J.; Jung, M. E.; Ahn, K.; Kim, J.; Lee, J. Bioorg. Med. Chem. Lett. 2008, 18, 2385. doi:10.1016/j.bmcl.2008.02.061 (Pubitemid 351442896)
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.7
, pp. 2385-2389
-
-
Kang, S.Y.1
Lee, S.-H.2
Seo, H.J.3
Jung, M.E.4
Ahn, K.5
Kim, J.6
Lee, J.7
-
120
-
-
33645886644
-
-
doi:10.1016/j.bmcl.2006.02.024
-
Muraglia, E.; Kinzel, O. D.; Laufer, R.; Miller, M. D.; Moyer, G.; Munshi, V.; Orvieto, F.; Palumbi, M. C.; Pescatore, G.; Rowley, M.; Williarns, P. D.; Summa, V. Bioorg. Med. Chem. Lett. 2006, 16, 2748. doi:10.1016/j.bmcl. 2006.02.024
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 2748
-
-
Muraglia, E.1
Kinzel, O.D.2
Laufer, R.3
Miller, M.D.4
Moyer, G.5
Munshi, V.6
Orvieto, F.7
Palumbi, M.C.8
Pescatore, G.9
Rowley, M.10
Williarns, P.D.11
Summa, V.12
-
121
-
-
34249327726
-
Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors
-
DOI 10.1016/j.bmcl.2007.03.097, PII S0960894X07004179
-
O'Meara, J. A.; Jakalian, A.; LaPlante, S.; Bonneau, P. R.; Coulombe, R.; Faucher, A. M.; Guse, I.; Landry, S.; Racine, J.; Simoneau, B.; Thavonekham, B.; Yoakim, C. Bioorg. Med. Chem. Lett. 2007, 17, 3362. doi:10.1016/j.bmcl.2007. 03.097 (Pubitemid 46819032)
-
(2007)
Bioorganic and Medicinal Chemistry Letters
, vol.17
, Issue.12
, pp. 3362-3366
-
-
O'Meara, J.A.1
Jakalian, A.2
LaPlante, S.3
Bonneau, P.R.4
Coulombe, R.5
Faucher, A.-M.6
Guse, I.7
Landry, S.8
Racine, J.9
Simoneau, B.10
Thavonekham, B.11
Yoakim, C.12
-
122
-
-
0037119735
-
3-modified Passerini MCC/N-capping strategy
-
DOI 10.1016/S0040-4039(02)01505-8, PII S0040403902015058
-
Nixey, T.; Hulme, C. Tetrahedron Lett. 2002, 43, 6833. doi:10.1016/S0040-4039(02)01505-8 (Pubitemid 35245905)
-
(2002)
Tetrahedron Letters
, vol.43
, Issue.38
, pp. 6833-6835
-
-
Nixey, T.1
Hulme, C.2
-
123
-
-
56749144015
-
-
doi:10.1002/anie.200804213
-
Yue, T.; Wang, M.-X.; Wang, D.-X.; Zhu, J. Angew. Chem., Int. Ed. 2008, 47, 9454. doi:10.1002/anie.200804213
-
(2008)
Angew. Chem., Int. Ed.
, vol.47
, pp. 9454
-
-
Yue, T.1
Wang, M.-X.2
Wang, D.-X.3
Zhu, J.4
-
124
-
-
25444507429
-
New cleavable isocyanides for the combinatorial synthesis of α-amino acid analogue tetrazoles
-
DOI 10.1016/j.tetlet.2005.08.101, PII S0040403905018502
-
Mayer, J.; Umkehrer, M.; Kalinski, C.; Ross, G.; Kolb, J.; Burdack, C.; Hiller, W. Tetrahedron Lett. 2005, 46, 7393. doi:10.1016/j.tetlet.2005.08.101 (Pubitemid 41365859)
-
(2005)
Tetrahedron Letters
, vol.46
, Issue.43
, pp. 7393-7396
-
-
Mayer, J.1
Umkehrer, M.2
Kalinski, C.3
Ross, G.4
Kolb, J.5
Burdack, C.6
Hiller, W.7
-
125
-
-
0037182215
-
The universal Rink-isonitrile resin: Applications in Ugi reactions
-
DOI 10.1016/S0040-4039(02)00700-1, PII S0040403902007001
-
Chen, J. J.; Golebiowski, A.; Klopfenstein, S. R.; West, L. Tetrahedron Lett. 2002, 43, 4083. doi:10.1016/S0040-4039(02)00700-1 (Pubitemid 34603233)
-
(2002)
Tetrahedron Letters
, vol.43
, Issue.22
, pp. 4083-4085
-
-
Chen, J.J.1
Golebiowski, A.2
Klopfenstein, S.R.3
West, L.4
-
126
-
-
84858121501
-
-
doi:10.1021/co200209a
-
Gunawan, S.; Petit, J.; Hulme, C. ACS Comb. Sci. 2012, 14, 160. doi:10.1021/co200209a
-
(2012)
ACS Comb. Sci.
, vol.14
, pp. 160
-
-
Gunawan, S.1
Petit, J.2
Hulme, C.3
-
127
-
-
84869432186
-
-
doi:10.1007/s11030-012-9373-2
-
Gunawan, S.; Keck, K.; Laetsch, A.; Hulme, C. Mol. Diversity 2012, 16, 601. doi:10.1007/s11030-012-9373-2
-
(2012)
Mol. Diversity
, vol.16
, pp. 601
-
-
Gunawan, S.1
Keck, K.2
Laetsch, A.3
Hulme, C.4
-
128
-
-
0034697723
-
-
doi:10.1039/B002258F
-
Maison, W.; Lützen, A.; Kosten, M.; Schlemminger, I.; Westerhoff, O.; Saak, W.; Martens, J. J. Chem. Soc., Perkin Trans. 1 2000, 1867. doi:10.1039/B002258F
-
(2000)
J. Chem. Soc., Perkin Trans.
, vol.1
, pp. 1867
-
-
Maison, W.1
Lützen, A.2
Kosten, M.3
Schlemminger, I.4
Westerhoff, O.5
Saak, W.6
Martens, J.7
-
129
-
-
0028889088
-
-
doi:10.1016/0040-4020(94)00958-W
-
Kehagia, K.; Dömling, A.; Ugi, I. Tetrahedron 1995, 51, 139-144. doi:10.1016/0040-4020(94)00958-W
-
(1995)
Tetrahedron
, vol.51
, pp. 139-144
-
-
Kehagia, K.1
Dömling, A.2
Ugi, I.3
-
130
-
-
0027397579
-
-
doi:10.1021/jo00056a018
-
Genin, M. J.; Gleason, W. B.; Johnson, R. L. J. Org. Chem. 1993, 58, doi:10.1021/jo00056a018.
-
(1993)
J. Org. Chem.
, vol.58
, pp. 860
-
-
Genin, M.J.1
Gleason, W.B.2
Johnson, R.L.3
-
131
-
-
33746833343
-
-
doi:10.1039/a905119h
-
Maison, W.; Lützen, A.; Kosten, M.; Schlemminger, I.; Westerhoff, O.; Martens, J. J. Chem. Soc., Perkin Trans. 1 1999, 3515. doi:10.1039/a905119h
-
(1999)
J. Chem. Soc., Perkin Trans.
, vol.1
, pp. 3515
-
-
Maison, W.1
Lützen, A.2
Kosten, M.3
Schlemminger, I.4
Westerhoff, O.5
Martens, J.6
-
132
-
-
12344254694
-
Synthesis of functionalized heterocycles via a tandem Staudinger/aza- Wittig/Ugi multicomponent reaction
-
DOI 10.1016/j.tetasy.2004.11.079, PII S0957416604009504
-
Timmer, M. S. M.; Risseeuw, M. D. P.; Verdoes, M.; Filippov, D. V.; Plaisier, J. R.; van der Marel, G. A.; Overkleeft, H. S.; van Boom, J. H. Tetrahedron: Asymmetry 2005, 16, 177. doi:10.1016/j.tetasy.2004.11.079 (Pubitemid 40127085)
-
(2005)
Tetrahedron Asymmetry
, vol.16
, Issue.1
, pp. 177-185
-
-
Timmer, M.S.M.1
Risseeuw, M.D.P.2
Verdoes, M.3
Filippov, D.V.4
Plaisier, J.R.5
Van Der Marel, G.A.6
Overkleeft, H.S.7
Van Boom, J.H.8
-
133
-
-
7544238813
-
Structure-based exploration of cyclic dipeptide chitinase inhibitors
-
DOI 10.1021/jm049940a
-
Houston, D. R.; Synstad, B.; Eijsink, V. G. H.; Stark, M. J. R.; Eggleston, I. M.; van Aalten, D. M. F. J. Med. Chem. 2004, 47, 5713. doi:10.1021/jm049940a (Pubitemid 39451826)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.23
, pp. 5713-5720
-
-
Houston, D.R.1
Synstad, B.2
Eijsink, V.G.H.3
Stark, M.J.R.4
Eggleston, I.M.5
Van Aalten, D.M.F.6
-
134
-
-
0037301172
-
-
doi:10.7164/antibiotics.56.102
-
Byun, H.-G.; Zhang, H.; Mochizuki, M.; Adachi, K.; Shizuri, Y.; Lee, W.-J.; Kim, S.-K. J. Antibiot. 2003, 56, 102. doi:10.7164/antibiotics.56.102
-
(2003)
J. Antibiot.
, vol.56
, pp. 102
-
-
Byun, H.-G.1
Zhang, H.2
Mochizuki, M.3
Adachi, K.4
Shizuri, Y.5
Lee, W.-J.6
Kim, S.-K.7
-
135
-
-
0242321129
-
DD-Diketopiperazines: Antibiotics Active against Vibrio anguillarum Isolated from Marine Bacteria Associated with Cultures of Pecten maximus
-
DOI 10.1021/np030233e
-
Fdhila, F.; Vazquez, V.; Sánchez, J. L.; Riguera, R. J. Nat. Prod. 2003, 66, 1299. doi:10.1021/np030233e (Pubitemid 37336444)
-
(2003)
Journal of Natural Products
, vol.66
, Issue.10
, pp. 1299-1301
-
-
Fdhila, F.1
Vazquez, V.2
Sanchez, J.L.3
Riguera, R.4
-
136
-
-
33646118484
-
-
doi:10.1097/01.cad.0000182745.01612.8a
-
Nicholson, B.; Lloyd, G. K.; Miller, B. R.; Palladino, M. A.; Kiso, Y.; Hayashi, Y.; Neuteboom, S. T. C. Anti-Cancer Drugs 2006, 17, 25. doi:10.1097/01.cad.0000182745.01612.8a
-
(2006)
Anti-Cancer Drugs
, vol.17
, pp. 25
-
-
Nicholson, B.1
Lloyd, G.K.2
Miller, B.R.3
Palladino, M.A.4
Kiso, Y.5
Hayashi, Y.6
Neuteboom, S.T.C.7
-
137
-
-
47649109637
-
-
doi:10.1016/j.peptides.2008.03.010
-
van der Merwe, E.; Huang, D.; Peterson, D.; Kilian, G.; Milne, P. J.; Van de Venter, M.; Frost, C. Peptides 2008, 29, 1305. doi:10.1016/j.peptides.2008. 03.010
-
(2008)
Peptides
, vol.29
, pp. 1305
-
-
Van Der Merwe, E.1
Huang, D.2
Peterson, D.3
Kilian, G.4
Milne, P.J.5
Van De Venter, M.6
Frost, C.7
-
139
-
-
25444474706
-
Structures, sensory activity, and dose/response functions of 2,5-diketopiperazines in roasted cocoa nibs (Theobroma cacao)
-
DOI 10.1021/jf051313m
-
Stark, T.; Hofmann, T. J. Agric. Food Chem. 2005, 53, 7222. doi:10.1021/jf051313m (Pubitemid 41375338)
-
(2005)
Journal of Agricultural and Food Chemistry
, vol.53
, Issue.18
, pp. 7222-7231
-
-
Stark, T.1
Hofmann, T.2
-
140
-
-
70449380027
-
-
doi:10.1021/cc900106u
-
Rhoden, C. R. B.; Rivera, D. G.; Kreye, O.; Bauer, A. K.; Westermann, B.; Wessjohann, L. A. J. Comb. Chem. 2009, 11, 1078. doi:10.1021/cc900106u
-
(2009)
J. Comb. Chem.
, vol.11
, pp. 1078
-
-
Rhoden, C.R.B.1
Rivera, D.G.2
Kreye, O.3
Bauer, A.K.4
Westermann, B.5
Wessjohann, L.A.6
-
141
-
-
78650869957
-
-
doi:10.1002/ejoc.201001330
-
Ressurreição, A. S. M.; Delatouche, R.; Gennari, C.; Piarulli, U. Eur. J. Org. Chem. 2011, 217. doi:10.1002/ejoc.201001330
-
(2011)
Eur. J. Org. Chem.
, pp. 217
-
-
Ressurreição, A.S.M.1
Delatouche, R.2
Gennari, C.3
Piarulli, U.4
-
142
-
-
84865081172
-
-
doi:10.1021/cr200398y
-
Borthwick, A. D. Chem. Rev. 2012, 112, 3641. doi:10.1021/cr200398y
-
(2012)
Chem. Rev.
, vol.112
, pp. 3641
-
-
Borthwick, A.D.1
-
143
-
-
0032485439
-
The solution phase synthesis of diketopiperazine libraries via the Ugi reaction: Novel application of Armstrong's convertible isonitrile.
-
DOI 10.1016/S0040-4039(97)10795-X, PII S004040399710795X
-
Hulme, C.; Morrissette, M. M.; Volz, F. A.; Burns, C. J. Tetrahedron Lett. 1998, 39, 1113. doi:10.1016/S0040-4039(97)10795-X (Pubitemid 28076183)
-
(1998)
Tetrahedron Letters
, vol.39
, Issue.10
, pp. 1113-1116
-
-
Hulme, C.1
Morrissette, M.M.2
Volz, F.A.3
Burns, C.J.4
-
144
-
-
0032191453
-
-
doi:10.1016/S0040-4039(98)01593-7
-
Hulme, C.; Peng, J.; Morton, G.; Salvino, J. M.; Herpin, T.; Labaudiniere, R. Tetrahedron Lett. 1998, 39, 7227. doi:10.1016/S0040-4039(98) 01593-7
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 7227
-
-
Hulme, C.1
Peng, J.2
Morton, G.3
Salvino, J.M.4
Herpin, T.5
Labaudiniere, R.6
-
145
-
-
0033575465
-
Novel applications of ethyl glyoxalate with the Ugi MCR
-
DOI 10.1016/S0040-4039(99)00960-0, PII S0040403999009600
-
Hulme, C.; Cherrier, M.-P. Tetrahedron Lett. 1999, 40, 5295. doi:10.1016/S0040-4039(99)00960-0 (Pubitemid 29317671)
-
(1999)
Tetrahedron Letters
, vol.40
, Issue.29
, pp. 5295-5299
-
-
Hulme, C.1
Cherrier, M.-P.2
-
147
-
-
0037018444
-
-
doi:10.1021/ol0256015
-
Kennedy, A. L.; Fryer, A. M.; Josey, J. A. Org. Lett. 2002, 4, 1167. doi:10.1021/ol0256015
-
(2002)
Org. Lett.
, vol.4
, pp. 1167
-
-
Kennedy, A.L.1
Fryer, A.M.2
Josey, J.A.3
-
148
-
-
0038103810
-
Synthesis of 3-methoxyquinolines via cyclization of 1-isocyano-2-(2- lithio-2-methoxyethenyl)benzenes
-
DOI 10.1016/S0040-4039(03)01040-2
-
Kobayashi, K.; Yoneda, K.; Mizumoto, T.; Umakoshi, H.; Morikawa, O.; Konishi, H. Tetrahedron Lett. 2003, 44, 4733. doi:10.1016/S0040-4039(03)01040-2 (Pubitemid 36647945)
-
(2003)
Tetrahedron Letters
, vol.44
, Issue.25
, pp. 4733-4736
-
-
Kobayashi, K.1
Yoneda, K.2
Mizumoto, T.3
Umakoshi, H.4
Morikawa, O.5
Konishi, H.6
-
149
-
-
66149185540
-
-
doi:10.1016/j.tetlet.2009.04.095
-
Hulme, C.; Chappeta, S.; Dietrich, J. Tetrahedron Lett. 2009, 50, 4054. doi:10.1016/j.tetlet.2009.04.095
-
(2009)
Tetrahedron Lett.
, vol.50
, pp. 4054
-
-
Hulme, C.1
Chappeta, S.2
Dietrich, J.3
-
150
-
-
20944434680
-
2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: Identification, stereochemistry and initial SAR
-
DOI 10.1016/j.bmcl.2005.03.045
-
Wyatt, P. G.; Allen, M. J.; Borthwick, A. D.; Davies, D. E.; Exall, A. M.; Hatley, R. J. D.; Irving, W. R.; Livermore, D. G.; Miller, N. D.; Nerozzi, F.; Sollis, S. L.; Szardenings, A. K. Bioorg. Med. Chem. Lett. 2005, 15, 2579. doi:10.1016/j.bmcl.2005.03.045 (Pubitemid 40614992)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.10
, pp. 2579-2582
-
-
Wyatt, P.G.1
Allen, M.J.2
Borthwick, A.D.3
Davies, D.E.4
Exall, A.M.5
Hatley, R.J.D.6
Irving, W.R.7
Livermore, D.G.8
Miller, N.D.9
Nerozzi, F.10
Sollis, S.L.11
Szardenings, A.K.12
-
151
-
-
27444444293
-
2,5-Diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics
-
DOI 10.1021/jm050557v
-
Borthwick, A. D.; Davies, D. E.; Exall, A. M.; Livermore, D. G.; Sollis, S. L.; Nerozzi, F.; Allen, M. J.; Perren, M.; Shabbir, S. S.; Woollard, P. M.; Wyatt, P. G. J. Med. Chem. 2005, 48, 6956. doi:10.1021/jm050557v (Pubitemid 41533117)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.22
, pp. 6956-6969
-
-
Borthwick, A.D.1
Davies, D.E.2
Exall, A.M.3
Livermore, D.G.4
Sollis, S.L.5
Nerozzi, F.6
Allen, M.J.7
Perren, M.8
Shabbir, S.S.9
Woollard, P.M.10
Wyatt, P.G.11
-
152
-
-
77956777485
-
-
doi:10.1021/jm901812z
-
Borthwick, A. D. J. Med. Chem. 2010, 53, 6525. doi:10.1021/jm901812z
-
(2010)
J. Med. Chem.
, vol.53
, pp. 6525
-
-
Borthwick, A.D.1
-
153
-
-
20344397439
-
Short and novel stereospecific synthesis of trisubstituted 2,5-diketopiperazines
-
DOI 10.1021/jo0501137
-
Sollis, S. L. J. Org. Chem. 2005, 70, 4735. doi:10.1021/jo0501137 (Pubitemid 40791700)
-
(2005)
Journal of Organic Chemistry
, vol.70
, Issue.12
, pp. 4735-4740
-
-
Sollis, S.L.1
-
154
-
-
0035795047
-
A facile synthesis of 2,5-diketopiperazines based on isocyanide chemistry
-
DOI 10.1016/S0040-4039(01)00232-5, PII S0040403901002325
-
Marcaccini, S.; Pepino, R.; Pozo, M. C. Tetrahedron Lett. 2001, 42, 2727. doi:10.1016/S0040-4039(01)00232-5 (Pubitemid 32245540)
-
(2001)
Tetrahedron Letters
, vol.42
, Issue.14
, pp. 2727-2728
-
-
Marcaccini, S.1
Pepino, R.2
Pozo, M.C.3
-
155
-
-
0030768259
-
Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics. Tetrahedron report number 426
-
DOI 10.1016/S0040-4020(97)00476-6, PII S0040402097004766
-
Hanessian, S.; McNaughton-Smith, G.; Lombart, H.-G.; Lubell, W. D. Tetrahedron 1997, 53, 12789. doi:10.1016/S0040-4020(97)00476-6 (Pubitemid 27380414)
-
(1997)
Tetrahedron
, vol.53
, Issue.38
, pp. 12789-12854
-
-
Hanessian, S.1
McNaughton-Smith, G.2
Lombart, H.-G.3
Lubell, W.D.4
-
156
-
-
0034710486
-
-
doi:10.1021/ol006145s
-
Golebiowski, A.; Klopfenstein, S. R.; Shao, X.; Chen, J. J.; Colson, A. O.; Grieb, A. L.; Russell, A. F. Org. Lett. 2000, 2, 2615. doi:10.1021/ol006145s
-
(2000)
Org. Lett.
, vol.2
, pp. 2615
-
-
Golebiowski, A.1
Klopfenstein, S.R.2
Shao, X.3
Chen, J.J.4
Colson, A.O.5
Grieb, A.L.6
Russell, A.F.7
-
157
-
-
0027231813
-
-
doi:10.1016/S0040-4020(01)90207-8
-
Ball, J. B.; Hughes, R. A.; Alewood, P. F.; Andrews, P. R. Tetrahedron 1993, 49, 3467. doi:10.1016/S0040-4020(01)90207-8
-
(1993)
Tetrahedron
, vol.49
, pp. 3467
-
-
Ball, J.B.1
Hughes, R.A.2
Alewood, P.F.3
Andrews, P.R.4
-
158
-
-
0034686345
-
-
doi:10.1016/S0040-4039(00)00669-9
-
Golebiowski, A.; Klopfenstein, S. R.; Chen, J. J.; Shao, X. Tetrahedron Lett. 2000, 41, 4841. doi:10.1016/S0040-4039(00)00669-9
-
(2000)
Tetrahedron Lett.
, vol.41
, pp. 4841
-
-
Golebiowski, A.1
Klopfenstein, S.R.2
Chen, J.J.3
Shao, X.4
-
160
-
-
18744377175
-
-
doi:10.1021/cc020029u
-
Golebiowski, A.; Jozwik, J.; Klopfenstein, S. R.; Colson, A.-O.; Grieb, A. L.; Russell, A. F.; Rastogi, V. L.; Diven, C. F.; Portlock, D. E.; Chen, J. J. J. Comb. Chem. 2002, 4, 584. doi:10.1021/cc020029u
-
(2002)
J. Comb. Chem.
, vol.4
, pp. 584
-
-
Golebiowski, A.1
Jozwik, J.2
Klopfenstein, S.R.3
Colson, A.-O.4
Grieb, A.L.5
Russell, A.F.6
Rastogi, V.L.7
Diven, C.F.8
Portlock, D.E.9
Chen, J.J.10
-
161
-
-
33846154262
-
A new approach to N-3 functionalized 3,4-dihydropyrimidine-2(1H)-ones with 1,2,4-oxadiazole group as amide isostere via ionic liquid-phase technology
-
DOI 10.1016/j.tetlet.2006.11.148, PII S0040403906023860
-
Legeay, J. C.; Vanden Eynde, J. J.; Bazureau, J. P. Tetrahedron Lett. 2007, 48, 1063. doi:10.1016/j.tetlet.2006.11.148 (Pubitemid 46075223)
-
(2007)
Tetrahedron Letters
, vol.48
, Issue.6
, pp. 1063-1068
-
-
Legeay, J.C.1
Vanden Eynde, J.J.2
Bazureau, J.P.3
-
162
-
-
0032191030
-
-
doi:10.1016/S0040-4020(98)00760-1
-
Ochoa, E.; Suárez, M.; Verdecia, Y.; Pita, B.; Martín, N.; Quinteiro, M.; Seoane, C.; Soto, J. L.; Duque, J.; Pomés, R. Tetrahedron 1998, 54, 12409. doi:10.1016/S0040-4020(98)00760-1
-
(1998)
Tetrahedron
, vol.54
, pp. 12409
-
-
Ochoa, E.1
Suárez, M.2
Verdecia, Y.3
Pita, B.4
Martín, N.5
Quinteiro, M.6
Seoane, C.7
Soto, J.L.8
Duque, J.9
Pomés, R.10
-
163
-
-
33845277540
-
Diastereoselective multicomponent synthesis of dihydropyridones with an isocyanide functionality
-
DOI 10.1021/ol062204b
-
Paravidino, M.; Bon, R. S.; Scheffelaar, R.; Vugts, D. J.; Znabet, A.; Schmitz, R. F.; de Kanter, F. J. J.; Lutz, M.; Spek, A. L.; Groen, M. B.; Orru, R. V. A. Org. Lett. 2006, 8, 5369. doi:10.1021/ol062204b (Pubitemid 44861570)
-
(2006)
Organic Letters
, vol.8
, Issue.23
, pp. 5369-5372
-
-
Paravidino, M.1
Bon, R.S.2
Scheffelaar, R.3
Vugts, D.J.4
Znabet, A.5
Schmitz, R.F.6
De Kanter, F.J.J.7
Lutz, M.8
Spek, A.L.9
Groen, M.B.10
Orru, R.V.A.11
-
164
-
-
37549063611
-
-
doi:10.1021/jo701978v
-
Paravidino, M.; Scheffelaar, R.; Schmitz, R. F.; De Kanter, F. J. J.; Groen, M. B.; Ruijter, E.; Orru, R. V. A. J. Org. Chem. 2007, 72, 10239. doi:10.1021/jo701978v
-
(2007)
J. Org. Chem.
, vol.72
, pp. 10239
-
-
Paravidino, M.1
Scheffelaar, R.2
Schmitz, R.F.3
De Kanter, F.J.J.4
Groen, M.B.5
Ruijter, E.6
Orru, R.V.A.7
-
165
-
-
0142156024
-
-
doi:10.1039/b308243a
-
Vugts, D. J.; Jansen, H.; Schmitz, R. F.; de Kanter, F. J. J.; Orru, R. V. A. Chem. Commun. 2003, 2594. doi:10.1039/b308243a
-
(2003)
Chem. Commun.
, pp. 2594
-
-
Vugts, D.J.1
Jansen, H.2
Schmitz, R.F.3
De Kanter, F.J.J.4
Orru, R.V.A.5
-
166
-
-
4544248532
-
Facile incorporation of urea pseudopeptides into protease substrate analogue inhibitors
-
DOI 10.1016/j.bmcl.2004.07.092, PII S0960894X04009102
-
Myers, A. C.; Kowalski, J. A.; Lipton, M. A. Bioorg. Med. Chem. Lett. 2004, 14, 5219. doi:10.1016/j.bmcl.2004.07.092 (Pubitemid 39233398)
-
(2004)
Bioorganic and Medicinal Chemistry Letters
, vol.14
, Issue.20
, pp. 5219-5222
-
-
Myers, A.C.1
Kowalski, J.A.2
Lipton, M.A.3
-
167
-
-
14744297865
-
-
doi:10.2174/0929867053362802
-
Zega, A. Curr. Med. Chem. 2005, 12, 589. doi:10.2174/0929867053362802
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 589
-
-
Zega, A.1
-
168
-
-
11844288256
-
A novel once-daily protease inhibitor
-
DOI 10.1358/dot.2004.40.11.872579
-
Piliero, P. J. Drugs Today 2004, 40, 901. doi:10.1358/dot.2004.40.11. 872579 (Pubitemid 40095997)
-
(2004)
Drugs of Today
, vol.40
, Issue.11
, pp. 901-912
-
-
Piliero, P.J.1
-
170
-
-
9944246065
-
A novel simple pyrolytic approach towards anhydronucleosides
-
DOI 10.1016/j.tetlet.2004.11.050, PII S004040390402502X
-
Al-Etalbi, A.; Makhseed, S.; Al-Awadi, N. A.; Ibrahim, Y. A. Tetrahedron Lett. 2005, 46, 31. doi:10.1016/j.tetlet.2004.11.050 (Pubitemid 39592937)
-
(2005)
Tetrahedron Letters
, vol.46
, Issue.1
, pp. 31-35
-
-
Al-Etaibi, A.1
Makhseed, S.2
Al-Awadi, N.A.3
Ibrahim, Y.A.4
-
171
-
-
13944258781
-
Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo[2,1-f][1,2,4] triazine based VEGFR-2 kinase inhibitors
-
DOI 10.1016/j.bmcl.2004.12.079
-
Borzilleri, R. M.; Cai, Z. W.; Ellis, C.; Fargnoli, J.; Fura, A.; Gerhardt, T.; Goyal, B.; Hunt, J. T.; Mortillo, S.; Qian, L. G.; Tokarski, J.; Vyas, V.; Wautlet, B.; Zheng, X.; Bhide, R. S. Bioorg. Med. Chem. Lett. 2005, 15, 1429. doi:10.1016/j.bmcl.2004.12.079 (Pubitemid 40269006)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.5
, pp. 1429-1433
-
-
Borzilleri, R.M.1
Cai, Z.-W.2
Ellis, C.3
Fargnoli, J.4
Fura, A.5
Gerhardt, T.6
Goyal, B.7
Hunt, J.T.8
Mortillo, S.9
Qian, L.10
Tokarski, J.11
Vyas, V.12
Wautlet, B.13
Zheng, X.14
Bhide, R.S.15
-
172
-
-
20444385804
-
Design, synthesis, and evaluation of orally active 4-(2,4-difluoro-5- (methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitors
-
DOI 10.1021/jm0501275
-
Borzilleri, R. M.; Zheng, X.; Qian, L.; Ellis, C.; Cai, Z.-w.; Wautlet, B. S.; Mortillo, S.; Jeyaseelan, R.; Kukral, D. W.; Fura, A.; Kamath, A.; Vyas, V.; Tokarski, J. S.; Barrish, J. C.; Hunt, J. T.; Lombardo, L. J.; Fargnoli, J.; Bhide, R. S. J. Med. Chem. 2005, 48, 3991. doi:10.1021/jm0501275 (Pubitemid 40800608)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.12
, pp. 3991-4008
-
-
Borzilleri, R.M.1
Zheng, X.2
Qian, L.3
Ellis, C.4
Cai, Z.-W.5
Wautlet, B.S.6
Mortillo, S.7
Jeyaseelan Sr., R.8
Kukral, D.W.9
Fura, A.10
Kamath, A.11
Vyas, V.12
Tokarski, J.S.13
Barrish, J.C.14
Hunt, J.T.15
Lombardo, L.J.16
Fargnoli, J.17
Bhide, R.S.18
-
173
-
-
3242806740
-
Discovery of the pyrrolo[2,1-f][1,2,4]triazine nucleus as a new kinase inhibitor template
-
DOI 10.1021/jm049892u
-
Hunt, J. T.; Mitt, T.; Borzilleri, R.; Gullo-Brown, J.; Fargnoli, J.; Fink, B.; Han, W.-C.; Mortillo, S.; Vite, G.; Wautlet, B.; Wong, T.; Yu, C.; Zheng, X.; Bhide, R. J. Med. Chem. 2004, 47, 4054. doi:10.1021/jm049892u (Pubitemid 38970966)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.16
, pp. 4054-4059
-
-
Hunt, J.T.1
Mitt, T.2
Borzilleri, R.3
Gullo-Brown, J.4
Fargnoli, J.5
Fink, B.6
Han, W.-C.7
Mortillo, S.8
Vite, G.9
Wautlet, B.10
Wong, T.11
Yu, C.12
Zheng, X.13
Bhide, R.14
-
174
-
-
33744942880
-
Synthesis of 3-hydroxy-6-oxo[1,2,4]triazin-1-yl alaninamides, a new class of cyclic dipeptidyl ureas
-
DOI 10.1021/jo060434y
-
Sañudo, M.; Marcaccini, S.; Basurto, S.; Torroba, T. J. Org. Chem. 2006, 71, 4578. doi:10.1021/jo060434y (Pubitemid 43849564)
-
(2006)
Journal of Organic Chemistry
, vol.71
, Issue.12
, pp. 4578-4584
-
-
Sanudo, M.1
Marcaccini, S.2
Basurto, S.3
Torroba, T.4
-
175
-
-
40949159648
-
A multicomponent synthesis of triazinane diones
-
DOI 10.1021/jo701973d
-
Groenendaal, B.; Vugts, D. J.; Schmitz, R. F.; de Kanter, F. J. J.; Ruijter, E.; Groen, M. B.; Orru, R. V. A. J. Org. Chem. 2008, 73, 719. doi:10.1021/jo701973d (Pubitemid 351437437)
-
(2008)
Journal of Organic Chemistry
, vol.73
, Issue.2
, pp. 719-722
-
-
Groenendaal, B.1
Vugts, D.J.2
Schmitz, R.F.3
De Kanter, F.J.J.4
Ruijter, E.5
Groen, M.B.6
Orru, R.V.A.7
-
176
-
-
49549118032
-
-
doi:10.1039/b807138a
-
Groenendaal, B.; Ruijter, E.; de Kanter, F. J. J.; Lutz, M.; Spek, A. L.; Orru, R. V. A. Org. Biomol. Chem. 2008, 6, 3158. doi:10.1039/b807138a
-
(2008)
Org. Biomol. Chem.
, vol.6
, pp. 3158
-
-
Groenendaal, B.1
Ruijter, E.2
De Kanter, F.J.J.3
Lutz, M.4
Spek, A.L.5
Orru, R.V.A.6
-
177
-
-
33749031569
-
Multicomponent synthesis of dihydropyrimidines and thiazines
-
DOI 10.1002/chem.200600168
-
Vugts, D. J.; Koningstein, M. M.; Schmitz, R. F.; de Kanter, F. J. J.; Groen, M. B.; Orru, R. V. A. Chem.-Eur. J. 2006, 12, 7178. doi:10.1002/chem. 200600168 (Pubitemid 44450141)
-
(2006)
Chemistry - A European Journal
, vol.12
, Issue.27
, pp. 7178-7189
-
-
Vugts, D.J.1
Koningstein, M.M.2
Schmitz, R.F.3
De Kanter, F.J.J.4
Groen, M.B.5
Orru, R.V.A.6
-
178
-
-
0030612066
-
2+ currents
-
DOI 10.1016/S0014-2999(96)00995-8, PII S0014299996009958
-
Koidl, B.; Miyawaki, N.; Tritthart, H. A. Eur. J. Pharmacol. 1997, 322, 243. doi:10.1016/S0014-2999(96)00995-8 (Pubitemid 27122900)
-
(1997)
European Journal of Pharmacology
, vol.322
, Issue.2-3
, pp. 243-247
-
-
Koidl, B.1
Miyawaki, N.2
Tritthart, H.A.3
-
179
-
-
15144340856
-
Protein structure-based design, synthesis, and biological evaluation of 5-thia-2,6-diamino-4(3H)-oxopyrimidines: Potent inhibitors of glycinamide ribonucleotide transformylase with potent cell growth inhibition
-
DOI 10.1021/jm9607459
-
Varney, M. D.; Palmer, C. L.; Romines, W. H., III; Boritzki, T.; Margosiak, S. A.; Almassy, R.; Janson, C. A.; Bartlett, C.; Howland, E. J.; Ferre, R. J. Med. Chem. 1997, 40, 2502. doi:10.1021/jm9607459 (Pubitemid 27347015)
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, Issue.16
, pp. 2502-2524
-
-
Varney, M.D.1
Palmer, C.L.2
Romines III, W.H.3
Boritzki, T.4
Margosiak, S.A.5
Almassy, R.6
Janson, C.A.7
Bartlett, C.8
Howland, E.J.9
Ferre, R.10
-
180
-
-
0037131704
-
Synthesis of thiomorpholines by an intramolecular Ugi reaction
-
DOI 10.1016/S0040-4039(02)02064-6, PII S0040403902020646
-
Marcaccini, S.; Pepino, R.; Torroba, T.; Miguel, D.; Garcia-Valverde, M. Tetrahedron Lett. 2002, 43, 8591. doi:10.1016/S0040-4039(02)02064-6 (Pubitemid 35238053)
-
(2002)
Tetrahedron Letters
, vol.43
, Issue.47
, pp. 8591-8593
-
-
Marcaccini, S.1
Pepino, R.2
Torroba, T.3
Miguel, D.4
Garcia-Valverde, M.5
-
181
-
-
0742304186
-
Highly Substituted Pyrrolidinones and Pyridones by 4-CR/2-CR Sequence
-
DOI 10.1021/ol035787n
-
Beck, B.; Picard, A.; Herdtweck, E.; Dömling, A. Org. Lett. 2004, 6, 39. doi:10.1021/ol035787n (Pubitemid 38160984)
-
(2004)
Organic Letters
, vol.6
, Issue.1
, pp. 39-42
-
-
Beck, B.1
Picard, A.2
Herdtweck, E.3
Domling, A.4
-
182
-
-
0028968716
-
-
doi:10.1021/jm00005a005
-
Breslin, H. J.; Kukla, M. J.; Ludovici, D. W.; Mohrbacher, R.; Ho, W.; Miranda, M.; Rodgers, J. D.; Hitchens, T. K.; Leo, G.; Gauthier, D. A.; Ho, C. Y.; Scott, M. K.; Declercq, E.; Pauwels, R.; Andries, K.; Janssen, M. A. C.; Janssen, P. A. J. J. Med. Chem. 1995, 38, 771. doi:10.1021/jm00005a005
-
(1995)
J. Med. Chem.
, vol.38
, pp. 771
-
-
Breslin, H.J.1
Kukla, M.J.2
Ludovici, D.W.3
Mohrbacher, R.4
Ho, W.5
Miranda, M.6
Rodgers, J.D.7
Hitchens, T.K.8
Leo, G.9
Gauthier, D.A.10
Ho, C.Y.11
Scott, M.K.12
Declercq, E.13
Pauwels, R.14
Andries, K.15
Janssen, M.A.C.16
Janssen, P.A.J.17
-
183
-
-
33744805804
-
Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents
-
DOI 10.1021/jm060405f
-
Micale, N.; Kozikowski, A. P.; Ettari, R.; Grasso, S.; Zappala, M.; Jeong, J.-J.; Kumar, A.; Hanspal, M.; Chishti, A. H. J. Med. Chem. 2006, 49, 3064. doi:10.1021/jm060405f (Pubitemid 43830505)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.11
, pp. 3064-3067
-
-
Micale, N.1
Kozikowski, A.P.2
Ettari, R.3
Grasso, S.4
Zappala, M.5
Jeong, J.-J.6
Kumar, A.7
Hanspal, M.8
Chishti, A.H.9
-
184
-
-
39749155747
-
Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors
-
DOI 10.1021/jm701141u
-
Ettari, R.; Nizi, E.; Di Francesco, M. E.; Dude, M.-A.; Pradel, G.; Vicik, R.; Schirmeister, T.; Micale, N.; Grasso, S.; Zappalà, M. J. Med. Chem. 2008, 51, 988. doi:10.1021/jm701141u (Pubitemid 351304707)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.4
, pp. 988-996
-
-
Ettari, R.1
Nizi, E.2
Di Francesco, M.E.3
Dude, M.-A.4
Pradel, G.5
Vicik, R.6
Schirmeister, T.7
Micale, N.8
Grasso, S.9
Zappala, M.10
-
185
-
-
19944431512
-
-
doi:10.1016/j.bmcl.2004.11.009
-
Parks, D. J.; LaFrance, L. V.; Calvo, R. R.; Milkiewicz, K. L.; Gupta, V.; Lattanze, J.; Ramachandren, K.; Carver, T. E.; Petrella, E. C.; Cummings, M. D.; Maguire, D.; Grasberger, B. L.; Lu, T. Bioorg. Med. Chem. Lett. 2005, 15, 765. doi:10.1016/j.bmcl.2004.11.009
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 765
-
-
Parks, D.J.1
Lafrance, L.V.2
Calvo, R.R.3
Milkiewicz, K.L.4
Gupta, V.5
Lattanze, J.6
Ramachandren, K.7
Carver, T.E.8
Petrella, E.C.9
Cummings, M.D.10
Maguire, D.11
Grasberger, B.L.12
Lu, T.13
-
186
-
-
33644873086
-
-
doi:10.1158/1535-7163.MCT-05-0199
-
Koblish, H. K.; Zhao, S. Y.; Franks, C. F.; Donatelli, R. R.; Tominovich, R. M.; LaFrance, L. V.; Leonard, K. A.; Gushue, J. M.; Parks, D. J.; Calvo, R. R.; Milkiewicz, K. L.; Marugán, J. J.; Raboisson, P.; Cummings, M. D.; Grasberger, B. L.; Johnson, D. L.; Lu, T.; Molloy, C. J.; Maroney, A. C. Mol. Cancer Ther. 2006, 5, 160. doi:10.1158/1535-7163.MCT-05-0199
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 160
-
-
Koblish, H.K.1
Zhao, S.Y.2
Franks, C.F.3
Donatelli, R.R.4
Tominovich, R.M.5
Lafrance, L.V.6
Leonard, K.A.7
Gushue, J.M.8
Parks, D.J.9
Calvo, R.R.10
Milkiewicz, K.L.11
Marugán, J.J.12
Raboisson, P.13
Cummings, M.D.14
Grasberger, B.L.15
Johnson, D.L.16
Lu, T.17
Molloy, C.J.18
Maroney, A.C.19
-
187
-
-
33746627694
-
Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity
-
DOI 10.1016/j.bmcl.2006.04.009, PII S0960894X06004215
-
Leonard, K.; Marugan, J. J.; Raboisson, P.; Calvo, R.; Gushue, J. M.; Koblish, H. K.; Lattanze, J.; Zhao, S.; Cummings, M. D.; Player, M. R.; Maroney, A. C.; Lu, T. Bioorg. Med. Chem. Lett. 2006, 16, 3463. doi:10.1016/j.bmcl.2006. 04.009 (Pubitemid 44226372)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.13
, pp. 3463-3468
-
-
Leonard, K.1
Marugan, J.J.2
Raboisson, P.3
Calvo, R.4
Gushue, J.M.5
Koblish, H.K.6
Lattanze, J.7
Zhao, S.8
Cummings, M.D.9
Player, M.R.10
Maroney, A.C.11
Lu, T.12
-
188
-
-
30844456191
-
A receptor subtype functions
-
DOI 10.1016/j.coph.2005.10.003, PII S1471489205001864
-
Rudolph, U.; Möhler, H. Curr. Opin. Pharmacol. 2006, 6, 18.
-
(2006)
Current Opinion in Pharmacology
, vol.6
, Issue.1 SPEC. ISS.
, pp. 18-23
-
-
Rudolph, U.1
Mohler, H.2
-
189
-
-
33749256952
-
2 receptors
-
DOI 10.1021/jm051222g
-
Rosenström, U.; Sköld, C.; Lindeberg, G.; Botros, M.; Nyberg, F.; Karlen, A.; Hallberg, A. J. Med. Chem. 2006, 49, 6133. doi:10.1021/jm051222g (Pubitemid 44484958)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.20
, pp. 6133-6137
-
-
Rosenstrom, U.1
Skold, C.2
Lindeberg, G.3
Botros, M.4
Nyberg, F.5
Karlen, A.6
Hallberg, A.7
-
190
-
-
78650177519
-
-
doi:10.1007/s11030-009-9210-4
-
Banfi, L.; Basso, A.; Cerulli, V.; Guanti, G.; Lecinska, P.; Monfardini, I.; Riva, R. Mol. Diversity 2010, 14, 425. doi:10.1007/s11030-009-9210-4
-
(2010)
Mol. Diversity
, vol.14
, pp. 425
-
-
Banfi, L.1
Basso, A.2
Cerulli, V.3
Guanti, G.4
Lecinska, P.5
Monfardini, I.6
Riva, R.7
-
191
-
-
35948997612
-
1,3,5-Trisubstituted 1,4-diazepin-2-ones
-
DOI 10.1021/jo701467d
-
Iden, H. S.; Lubell, W. D. J. Org. Chem. 2007, 72, 8980. doi:10.1021/jo701467d (Pubitemid 350071736)
-
(2007)
Journal of Organic Chemistry
, vol.72
, Issue.23
, pp. 8980-8983
-
-
Iden, H.S.1
Lubell, W.D.2
-
192
-
-
0037463502
-
NAr methodology. Part 2: Novel three-step solution phase access to libraries of benzodiazepines
-
DOI 10.1016/S0040-4039(03)00084-4
-
Tempest, P.; Pettus, L.; Gore, V.; Hulme, C. Tetrahedron Lett. 2003, 44, 1947. doi:10.1016/S0040-4039(03)00084-4 (Pubitemid 36183439)
-
(2003)
Tetrahedron Letters
, vol.44
, Issue.9
, pp. 1947-1950
-
-
Tempest, P.1
Pettus, L.2
Gore, V.3
Hulme, C.4
-
193
-
-
33947263255
-
Ugi multicomponent reaction followed by an intramolecular nucleophilic substitution: Convergent multicomponent synthesis of 1-sulfonyl 1,4-diazepan-5-ones and of their benzo-fused derivatives
-
DOI 10.1021/jo062626z
-
Banfi, L.; Basso, A.; Guanti, G.; Kielland, N.; Repetto, C.; Riva, R. J. Org. Chem. 2007, 72, 2151. doi:10.1021/jo062626z (Pubitemid 46418421)
-
(2007)
Journal of Organic Chemistry
, vol.72
, Issue.6
, pp. 2151-2160
-
-
Banfi, L.1
Basso, A.2
Guanti, G.3
Kielland, N.4
Repetto, C.5
Riva, R.6
-
194
-
-
74049098278
-
-
doi:10.1021/cc900157w
-
Zhou, H.; Zhang, W.; Yan, B. J. Comb. Chem. 2010, 12, 206. doi:10.1021/cc900157w
-
(2010)
J. Comb. Chem.
, vol.12
, pp. 206
-
-
Zhou, H.1
Zhang, W.2
Yan, B.3
-
195
-
-
61749088224
-
-
doi:10.1016/j.tetlet.2009.02.099
-
Hulme, C.; Chappeta, S.; Griffith, C.; Lee, Y.-S.; Dietrich, J. Tetrahedron Lett. 2009, 50, 1939. doi:10.1016/j.tetlet.2009.02.099
-
(2009)
Tetrahedron Lett.
, vol.50
, pp. 1939
-
-
Hulme, C.1
Chappeta, S.2
Griffith, C.3
Lee, Y.-S.4
Dietrich, J.5
-
196
-
-
64249145893
-
-
doi:10.1021/jo8025862
-
Sañudo, M.; García-Valverde, M.; Marcaccini, S.; Delgado, J. J.; Rojo, J.; Torroba, T. J. Org. Chem. 2009, 74, 2189. doi:10.1021/jo8025862
-
(2009)
J. Org. Chem.
, vol.74
, pp. 2189
-
-
Sañudo, M.1
García-Valverde, M.2
Marcaccini, S.3
Delgado, J.J.4
Rojo, J.5
Torroba, T.6
-
197
-
-
77955470708
-
-
doi:10.1016/j.tet.2010.06.062
-
Lecinska, P.; Corres, N.; Moreno, D.; García-Valverde, M.; Marcaccini, S.; Torroba, T. Tetrahedron 2010, 66, 6783. doi:10.1016/j.tet.2010. 06.062
-
(2010)
Tetrahedron
, vol.66
, pp. 6783
-
-
Lecinska, P.1
Corres, N.2
Moreno, D.3
García-Valverde, M.4
Marcaccini, S.5
Torroba, T.6
-
198
-
-
77954366814
-
-
doi:10.1111/j.1747-0285.2010.00989.x
-
Huang, Y.; Wolf, S.; Bista, M.; Meireles, L.; Camacho, C.; Holak, T. A.; Dömling, A. Chem. Biol. Drug Des. 2010, 76, 116. doi:10.1111/j.1747-0285. 2010.00989.x
-
(2010)
Chem. Biol. Drug Des.
, vol.76
, pp. 116
-
-
Huang, Y.1
Wolf, S.2
Bista, M.3
Meireles, L.4
Camacho, C.5
Holak, T.A.6
Dömling, A.7
-
199
-
-
79959423550
-
-
SI-part
-
Puterova, Z.; Krutosikova, A.; Vegh, D. ARKIVOC 2010, (i), 209. SI-part.
-
(2010)
ARKIVOC
, Issue.1
, pp. 209
-
-
Puterova, Z.1
Krutosikova, A.2
Vegh, D.3
-
200
-
-
79953294223
-
-
doi:10.1007/s11030-010-9229-6
-
Huang, Y.; Dömling, A. Mol. Diversity 2011, 15, 3. doi:10.1007/s11030-010-9229-6
-
(2011)
Mol. Diversity
, vol.15
, pp. 3
-
-
Huang, Y.1
Dömling, A.2
-
201
-
-
77954375071
-
-
doi:10.1111/j.1747-0285.2010.00990.x
-
Huang, Y.; Dömling, A. Chem. Biol. Drug Des. 2010, 76, 130. doi:10.1111/j.1747-0285.2010.00990.x
-
(2010)
Chem. Biol. Drug Des.
, vol.76
, pp. 130
-
-
Huang, Y.1
Dömling, A.2
-
202
-
-
0037071230
-
Short solution phase preparation of fused azepine-tetrazoles via a UDC (Ugi/de-Boc/cyclize) strategy
-
DOI 10.1016/S0040-4039(02)00636-6, PII S0040403902006366
-
Nixey, T.; Kelly, M.; Semin, D.; Hulme, C. Tetrahedron Lett. 2002, 43, 3681. doi:10.1016/S0040-4039(02)00636-6 (Pubitemid 34461862)
-
(2002)
Tetrahedron Letters
, vol.43
, Issue.20
, pp. 3681-3684
-
-
Nixey, T.1
Kelly, M.2
Semin, D.3
Hulme, C.4
-
203
-
-
71649105855
-
-
doi:10.1016/j.tetlet.2009.11.051
-
Nayak, M.; Batra, S. Tetrahedron Lett. 2010, 51, 510. doi:10.1016/j.tetlet.2009.11.051
-
(2010)
Tetrahedron Lett.
, vol.51
, pp. 510
-
-
Nayak, M.1
Batra, S.2
-
204
-
-
84861998944
-
-
doi:10.1016/j.tet.2012.04.068
-
Gunawan, S.; Ayaz, M.; De Moliner, F.; Frett, B.; Kaiser, C.; Patrick, N.; Xu, Z.; Hulme, C. Tetrahedron 2012, 68, 5606. doi:10.1016/j.tet.2012.04.068
-
(2012)
Tetrahedron
, vol.68
, pp. 5606
-
-
Gunawan, S.1
Ayaz, M.2
De Moliner, F.3
Frett, B.4
Kaiser, C.5
Patrick, N.6
Xu, Z.7
Hulme, C.8
-
205
-
-
79959774013
-
-
doi:10.1039/c1cc12263k
-
Gao, K.; Yu, C.-B.; Li, W.; Zhou, Y.-G.; Zhang, X. Chem. Commun. 2011, 47, 7845. doi:10.1039/c1cc12263k
-
(2011)
Chem. Commun.
, vol.47
, pp. 7845
-
-
Gao, K.1
Yu, C.-B.2
Li, W.3
Zhou, Y.-G.4
Zhang, X.5
-
206
-
-
0034615061
-
N-formyl hydroxylamine containing dipeptides: Generation of a new class of vasopeptidase inhibitors
-
DOI 10.1016/S0960-894X(99)00671-X, PII S0960894X9900671X
-
Robl, J. A.; Simpkins, L. M.; Asaad, M. M. Bioorg. Med. Chem. Lett. 2000, 10, 257. doi:10.1016/S0960-894X(99)00671-X (Pubitemid 30105384)
-
(2000)
Bioorganic and Medicinal Chemistry Letters
, vol.10
, Issue.3
, pp. 257-260
-
-
Robl, J.A.1
Simpkins, L.M.2
Asaad, M.M.3
-
207
-
-
0022624227
-
-
Nagarajan, K.; David, J.; Kulkarni, Y. S.; Hendi, S. B.; Shenoy, S. J.; Upadhyaya, P. Eur. J. Med. Chem. 1986, 21, 21.
-
(1986)
Eur. J. Med. Chem.
, vol.21
, pp. 21
-
-
Nagarajan, K.1
David, J.2
Kulkarni, Y.S.3
Hendi, S.B.4
Shenoy, S.J.5
Upadhyaya, P.6
-
208
-
-
0026747721
-
-
doi:10.1021/jm00088a027
-
Klunder, J. M.; Hargrave, K. D.; West, M. A.; Cullen, E.; Pal, K.; Behnke, M. L.; Kapadia, S. R.; Mcneil, D. W.; Wu, J. C.; Chow, G. C.; Adams, J. J. Med. Chem. 1992, 35, 1887. doi:10.1021/jm00088a027
-
(1992)
J. Med. Chem.
, vol.35
, pp. 1887
-
-
Klunder, J.M.1
Hargrave, K.D.2
West, M.A.3
Cullen, E.4
Pal, K.5
Behnke, M.L.6
Kapadia, S.R.7
McNeil, D.W.8
Wu, J.C.9
Chow, G.C.10
Adams, J.11
-
209
-
-
33750506949
-
Multicomponent synthesis of dihydrobenzoxazepinones by coupling Ugi and Mitsunobu reactions
-
DOI 10.1039/b613056a
-
Banfi, L.; Basso, A.; Guanti, G.; Lecinska, P.; Riva, R. Org. Biomol. Chem. 2006, 4, 4236. doi:10.1039/b613056a (Pubitemid 44665197)
-
(2006)
Organic and Biomolecular Chemistry
, vol.4
, Issue.22
, pp. 4236-4240
-
-
Banfi, L.1
Guanti, A.B.G.2
Lecinska, P.3
Riva, R.4
-
210
-
-
79960424447
-
-
doi:10.3762/bjoc.7.109
-
Banfi, L.; Basso, A.; Cerulli, V.; Rocca, V.; Riva, R. Beilstein J. Org. Chem. 2011, 7, 976. doi:10.3762/bjoc.7.109
-
(2011)
Beilstein J. Org. Chem.
, vol.7
, pp. 976
-
-
Banfi, L.1
Basso, A.2
Cerulli, V.3
Rocca, V.4
Riva, R.5
-
211
-
-
33644881901
-
One-step assembly of carbamoyl substituted annulated 1,4-oxazepines
-
DOI 10.1016/j.tetlet.2006.01.158, PII S0040403906002462
-
Ilyin, A. P.; Parchinski, V. Z.; Peregudova, J. N.; Trifilenkov, A. S.; Poutsykina, E. B.; Tkachenko, S. E.; Kravchenko, D. V.; Ivachtchenko, A. V. Tetrahedron Lett. 2006, 47, 2649. doi:10.1016/j.tetlet.2006.01.158 (Pubitemid 43383961)
-
(2006)
Tetrahedron Letters
, vol.47
, Issue.15
, pp. 2649-2653
-
-
Ilyin, A.P.1
Parchinski, V.Z.2
Peregudova, J.N.3
Trifilenkov, A.S.4
Poutsykina, E.B.5
Tkachenko, S.E.6
Kravchenko, D.V.7
Ivachtchenko, A.V.8
-
212
-
-
0141741234
-
Application of tandem Ugi reaction/ring-closing metathesis in multicomponent synthesis of unsaturated nine-membered lactams
-
DOI 10.1016/j.tetlet.2003.08.027
-
Banfi, L.; Basso, A.; Guanti, G.; Riva, R. Tetrahedron Lett. 2003, 44, 7655. doi:10.1016/j.tetlet.2003.08.027 (Pubitemid 37130238)
-
(2003)
Tetrahedron Letters
, vol.44
, Issue.41
, pp. 7655-7658
-
-
Banfi, L.1
Basso, A.2
Guanti, G.3
Riva, R.4
-
213
-
-
0141958105
-
3 integrin ligands: Pharmacophore refinement and implications for drug design
-
DOI 10.1021/jm020577m
-
Marinelli, L.; Lavecchia, A.; Gottschalk, K.-E.; Novellino, E.; Kessler, H. J. Med. Chem. 2003, 46, 4393. doi:10.1021/jm020577m (Pubitemid 37238743)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.21
, pp. 4393-4404
-
-
Marinelli, L.1
Lavecchia, A.2
Gottschalk, K.-E.3
Novellino, E.4
Kessler, H.5
-
214
-
-
0037131442
-
-
doi:10.1002/1521-3773(20021018)41:20<3767::AID-ANIE3767>3.0.C O;2-T
-
Gottschalk, K.-E.; Kessler, H. Angew. Chem., Int. Ed. 2002, 41, 3767. doi:10.1002/1521-3773(20021018)41:20<3767::AID-ANIE3767>3.0.C O;2-T
-
(2002)
Angew. Chem., Int. Ed.
, vol.41
, pp. 3767
-
-
Gottschalk, K.-E.1
Kessler, H.2
-
217
-
-
84868563717
-
-
doi:10.1021/mp3002733
-
Danhier, F.; Le Breton, A.; Préat, V. Mol. Pharmaceutics 2012, 9, 2961. doi:10.1021/mp3002733
-
(2012)
Mol. Pharmaceutics
, vol.9
, pp. 2961
-
-
Danhier, F.1
Le Breton, A.2
Préat, V.3
-
218
-
-
33846897471
-
Synthesis and biological evaluation of new conformationally biased integrin ligands based on a tetrahydroazoninone scaffold
-
DOI 10.1016/j.bmcl.2006.11.085, PII S0960894X06013771
-
Banfi, L.; Basso, A.; Damonte, G.; De Pellegrini, F.; Galatini, A.; Guanti, G.; Monfardini, I.; Riva, R.; Scapolla, C. Bioorg. Med. Chem. Lett. 2007, 17, 1341. doi:10.1016/j.bmcl.2006.11.085 (Pubitemid 46240835)
-
(2007)
Bioorganic and Medicinal Chemistry Letters
, vol.17
, Issue.5
, pp. 1341-1345
-
-
Banfi, L.1
Basso, A.2
Damonte, G.3
Pellegrini, F.D.4
Galatini, A.5
Guanti, G.6
Monfardini, I.7
Riva, R.8
Scapolla, C.9
-
219
-
-
79959580534
-
-
doi:10.1038/nchem.1062
-
White, C. J.; Yudin, A. K. Nat. Chem. 2011, 3, 509. doi:10.1038/nchem. 1062
-
(2011)
Nat. Chem.
, vol.3
, pp. 509
-
-
White, C.J.1
Yudin, A.K.2
-
220
-
-
79955562617
-
-
doi:10.1073/pnas.1015267108
-
Isidro-Llobet, A.; Murillo, T.; Bello, P.; Cilibrizzi, A.; Hodgkinson, J. T.; Galloway, W. R. J. D.; Bender, A.; Welch, M.; Spring, D. R. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 6793. doi:10.1073/pnas.1015267108
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 6793
-
-
Isidro-Llobet, A.1
Murillo, T.2
Bello, P.3
Cilibrizzi, A.4
Hodgkinson, J.T.5
Galloway, W.R.J.D.6
Bender, A.7
Welch, M.8
Spring, D.R.9
-
221
-
-
77952128317
-
-
doi:10.1002/chem.200903549
-
Yoo, B.; Shin, S. B. Y.; Huang, M. L.; Kirshenbaum, K. Chem.-Eur. J. 2010, 16, 5528. doi:10.1002/chem.200903549
-
(2010)
Chem.-Eur. J.
, vol.16
, pp. 5528
-
-
Yoo, B.1
Shin, S.B.Y.2
Huang, M.L.3
Kirshenbaum, K.4
-
222
-
-
0041475925
-
The cyclization of peptides and depsipeptides
-
DOI 10.1002/psc.491
-
Davies, J. S. J. Pept. Sci. 2003, 9, 471. doi:10.1002/psc.491 (Pubitemid 37009926)
-
(2003)
Journal of Peptide Science
, vol.9
, Issue.8
, pp. 471-501
-
-
Davies, J.S.1
-
223
-
-
33744543076
-
Skeletal diversity by allylation/RCM on Ugi four-component coupling reaction products
-
DOI 10.1016/j.tetlet.2006.04.098, PII S0040403906008227
-
Oikawa, M.; Naito, S.; Sasaki, M. Tetrahedron Lett. 2006, 47, 4763. doi:10.1016/j.tetlet.2006.04.098 (Pubitemid 43815465)
-
(2006)
Tetrahedron Letters
, vol.47
, Issue.27
, pp. 4763-4767
-
-
Oikawa, M.1
Naito, S.2
Sasaki, M.3
-
225
-
-
0037932800
-
Short and diverse route toward complex natural product-like macrocycles
-
DOI 10.1021/ol034077e
-
Beck, B.; Larbig, G.; Mejat, B.; Magnin-Lachaux, M.; Picard, A.; Herdtweck, E.; Dömling, A. Org. Lett. 2003, 5, 1047. doi:10.1021/ol034077e (Pubitemid 37141032)
-
(2003)
Organic Letters
, vol.5
, Issue.7
, pp. 1047-1050
-
-
Beck, B.1
Larbig, G.2
Mejat, B.3
Magnin-Lachaux, M.4
Picard, A.5
Herdtweck, E.6
Domling, A.7
-
226
-
-
0034808305
-
Activation of a terminal carboxylic acid by an internal oxazole: A novel synthesis of macrocyclodepsipeptide [3]
-
DOI 10.1021/ja015854d
-
Zhao, G.; Sun, X.; Bienaymé, H.; Zhu, J. J. Am. Chem. Soc. 2001, 123, 6700. doi:10.1021/ja015854d (Pubitemid 32916466)
-
(2001)
Journal of the American Chemical Society
, vol.123
, Issue.27
, pp. 6700-6701
-
-
Zhao, G.1
Sun, X.2
Bienayme, H.3
Zhu, J.4
-
227
-
-
31344466498
-
5-Aminooxazole as an internal traceless activator of C-terminal carboxylic acid: Rapid access to diversely functionalized cyclodepsipeptides
-
DOI 10.1002/chem.200500703
-
Bughin, C.; Zhao, G.; Bienaymé, H.; Zhu, J. Chem.-Eur. J. 2006, 12, 1174. doi:10.1002/chem.200500703 (Pubitemid 43145165)
-
(2006)
Chemistry - A European Journal
, vol.12
, Issue.4
, pp. 1174-1184
-
-
Bughin, C.1
Zhao, G.2
Bienayme, H.3
Zhu, J.4
-
228
-
-
77957570418
-
-
doi:10.1016/j.bmc.2010.08.032
-
Socha, A. M.; Tan, N. Y.; LaPlante, K. L.; Sello, J. K. Bioorg. Med. Chem. 2010, 18, 7193. doi:10.1016/j.bmc.2010.08.032
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 7193
-
-
Socha, A.M.1
Tan, N.Y.2
Laplante, K.L.3
Sello, J.K.4
-
229
-
-
84861186622
-
-
doi:10.1016/j.tetlet.2012.04.034
-
Samarasimhareddy, M.; Hemantha, H. P.; Sureshbabu, V. V. Tetrahedron Lett. 2012, 53, 3104. doi:10.1016/j.tetlet.2012.04.034
-
(2012)
Tetrahedron Lett.
, vol.53
, pp. 3104
-
-
Samarasimhareddy, M.1
Hemantha, H.P.2
Sureshbabu, V.V.3
-
230
-
-
33748925555
-
One-pot synthesis of macrocycles by a tandem three-component reaction and intramolecular [3+2] cycloaddition
-
DOI 10.1021/ol061782p
-
Pirali, T.; Tron, G. C.; Zhu, J. Org. Lett. 2006, 8, 4145. doi:10.1021/ol061782p (Pubitemid 44432873)
-
(2006)
Organic Letters
, vol.8
, Issue.18
, pp. 4145-4148
-
-
Pirali, T.1
Tron, G.C.2
Zhu, J.3
-
231
-
-
0033516914
-
-
doi:10.1002/(SICI)1521-3773(19990802)38:15<2096::AID-ANIE2096>3.0. CO;2-F
-
Nicolaou, K. C.; Boddy, C. N. C.; Bräse, S.; Winssinger, N. Angew. Chem., Int. Ed. 1999, 38, 2097. doi:10.1002/(SICI)1521-3773(19990802)38: 15<2096::AID-ANIE2096>3.0.CO;2-F
-
(1999)
Angew. Chem., Int. Ed.
, vol.38
, pp. 2097
-
-
Nicolaou, K.C.1
Boddy, C.N.C.2
Bräse, S.3
Winssinger, N.4
-
232
-
-
0030912795
-
-
doi:10.1039/np9971400075
-
Gournelis, D. C.; Laskaris, G. G.; Verpoorte, R. Nat. Prod. Rep. 1997, 14, 75. doi:10.1039/np9971400075
-
(1997)
Nat. Prod. Rep.
, vol.14
, pp. 75
-
-
Gournelis, D.C.1
Laskaris, G.G.2
Verpoorte, R.3
-
233
-
-
0002805426
-
-
doi:10.3987/COM-93-6382
-
Itokawa, H.; Kondo, K.; Hitotsuyanagi, Y.; Takeya, K. Heterocycles 1993, 36, 1837. doi:10.3987/COM-93-6382
-
(1993)
Heterocycles
, vol.36
, pp. 1837
-
-
Itokawa, H.1
Kondo, K.2
Hitotsuyanagi, Y.3
Takeya, K.4
-
234
-
-
0022998021
-
-
doi:10.7164/antibiotics.39.1674
-
Sano, S.; Ikai, K.; Kuroda, H.; Nakamura, T.; Obayashi, A.; Ezure, Y.; Enomoto, H. J. Antibiot. 1986, 39, 1674. doi:10.7164/antibiotics.39.1674
-
(1986)
J. Antibiot.
, vol.39
, pp. 1674
-
-
Sano, S.1
Ikai, K.2
Kuroda, H.3
Nakamura, T.4
Obayashi, A.5
Ezure, Y.6
Enomoto, H.7
-
235
-
-
6344258480
-
Cyclopeptide alkaloids: Chemistry and biology
-
DOI 10.1039/b400334a
-
Joullié, M. M.; Richard, D. J. Chem. Commun. 2004, 2011. doi:10.1039/B400334A (Pubitemid 39389490)
-
(2004)
Chemical Communications
, Issue.18
, pp. 2011-2015
-
-
Joullie, M.M.1
Richard, D.J.2
-
236
-
-
0023251049
-
-
doi:10.7164/antibiotics.40.455
-
Yasuzawa, T.; Shirahata, K.; Sano, H. J. Antibiot. 1987, 40, 455. doi:10.7164/antibiotics.40.455
-
(1987)
J. Antibiot.
, vol.40
, pp. 455
-
-
Yasuzawa, T.1
Shirahata, K.2
Sano, H.3
-
237
-
-
15444377930
-
What can a chemist learn from nature's macrocycles? - A brief, conceptual view
-
DOI 10.1007/s11030-005-1314-x
-
Wessjohann, L. A.; Ruijter, E.; Garcia-Rivera, D.; Brandt, W. Mol. Diversity 2005, 9, 171. doi:10.1007/s11030-005-1314-x (Pubitemid 40394851)
-
(2005)
Molecular Diversity
, vol.9
, Issue.1-3
, pp. 171-186
-
-
Wessjohann, L.A.1
Ruijter, E.2
Garcia-Rivera, D.3
Brandt, W.4
-
238
-
-
0035856895
-
NAr-based cycloetherification
-
DOI 10.1021/ol0168420
-
Cristau, P.; Vors, J.-P.; Zhu, J. Org. Lett. 2001, 3, 4079. doi:10.1021/ol0168420 (Pubitemid 33629545)
-
(2001)
Organic Letters
, vol.3
, Issue.25
, pp. 4079-4082
-
-
Cristau, P.1
Vors, J.-P.2
Zhu, J.3
-
239
-
-
0141852318
-
Rapid and diverse route to natural product-like biaryl ether containing macrocycles
-
DOI 10.1016/j.tet.2003.08.031
-
Cristau, P.; Vors, J.-P.; Zhu, J. Tetrahedron 2003, 59, 7859. doi:10.1016/j.tet.2003.08.031 (Pubitemid 37130308)
-
(2003)
Tetrahedron
, vol.59
, Issue.40
, pp. 7859-7870
-
-
Cristau, P.1
Vors, J.-P.2
Zhu, J.3
-
240
-
-
0037492348
-
NAr-based cycloetherification
-
DOI 10.1016/S0040-4039(03)01378-9
-
Cristau, P.; Vors, J.-P.; Zhu, J. Tetrahedron Lett. 2003, 44, 5575. doi:10.1016/S0040-4039(03)01378-9 (Pubitemid 36782582)
-
(2003)
Tetrahedron Letters
, vol.44
, Issue.30
, pp. 5575-5578
-
-
Cristau, P.1
Vors, J.-P.2
Zhu, J.3
-
241
-
-
33745783494
-
NAr reaction
-
DOI 10.1002/qsar.200540214
-
Cristau, P.; Vors, J.-P.; Zhu, J. QSAR Comb. Sci. 2006, 25, 519. doi:10.1002/qsar.200540214 (Pubitemid 44022729)
-
(2006)
QSAR and Combinatorial Science
, vol.25
, Issue.5-6
, pp. 519-526
-
-
Cristau, P.1
Vors, J.-P.2
Zhu, J.3
-
242
-
-
0035801852
-
Concise total synthesis of the prolyl endopeptidase inhibitor eurystatin A via a novel Passerini reaction-deprotection-acyl migration strategy
-
DOI 10.1016/S0040-4039(01)01287-4, PII S0040403901012874
-
Owens, T. D.; Araldi, G. L.; Nutt, R. F.; Semple, J. E. Tetrahedron Lett. 2001, 42, 6271. doi:10.1016/S0040-4039(01)01287-4 (Pubitemid 32772671)
-
(2001)
Tetrahedron Letters
, vol.42
, Issue.36
, pp. 6271-6274
-
-
Owens, T.D.1
Araldi, G.-L.2
Nutt, R.F.3
Semple J.Edward4
-
243
-
-
64349097304
-
-
doi:10.1021/ol900048r
-
Faure, S.; Hjelmgaard, T.; Roche, S. P.; Aitken, D. J. Org. Lett. 2009, 11, 1167. doi:10.1021/ol900048r
-
(2009)
Org. Lett.
, vol.11
, pp. 1167
-
-
Faure, S.1
Hjelmgaard, T.2
Roche, S.P.3
Aitken, D.J.4
-
244
-
-
38749096301
-
-
doi:10.1021/ol702521g
-
Vercillo, O. E.; Andrade, C. K. Z.; Wessjohann, L. A. Org. Lett. 2008, 10, 205. doi:10.1021/ol702521g
-
(2008)
Org. Lett.
, vol.10
, pp. 205
-
-
Vercillo, O.E.1
Andrade, C.K.Z.2
Wessjohann, L.A.3
-
245
-
-
43249115971
-
Rapid generation of macrocycles with natural-product-like side chains by multiple multicomponent macrocyclizations (MiBs)
-
DOI 10.1039/b715393g
-
Rivera, D. G.; Vercillo, O. E.; Wessjohann, L. A. Org. Biomol. Chem. 2008, 6, 1787. doi:10.1039/b715393g (Pubitemid 351649285)
-
(2008)
Organic and Biomolecular Chemistry
, vol.6
, Issue.10
, pp. 1787-1795
-
-
Rivera, D.G.1
Vercillo, O.E.2
Wessjohann, L.A.3
-
247
-
-
41149178159
-
Multiple multicomponent macrocyclizations including bifunctional building blocks (MiBs) based on Staudinger and Passerini three-component reactions
-
DOI 10.1021/jo7022125
-
Leon, F.; Rivera, D. G.; Wessjohann, L. A. J. Org. Chem. 2008, 73, 1762. doi:10.1021/jo7022125 (Pubitemid 351438891)
-
(2008)
Journal of Organic Chemistry
, vol.73
, Issue.5
, pp. 1762-1767
-
-
Leon, F.1
Rivera, D.G.2
Wessjohann, L.A.3
-
248
-
-
84877296198
-
-
doi:10.1002/chem.201201591 See for a recent related work in this area
-
Rivera, D. G.; Leon, F.; Concepcion, O.; Morales, F. E.; Wessjohann, L. A. Chem.-Eur. J. 2013, 19, 6417. doi:10.1002/chem.201201591 See for a recent related work in this area.
-
(2013)
Chem.-Eur. J.
, vol.19
, pp. 6417
-
-
Rivera, D.G.1
Leon, F.2
Concepcion, O.3
Morales, F.E.4
Wessjohann, L.A.5
-
249
-
-
77950402397
-
-
doi:10.1021/ja910544p
-
Hili, R.; Rai, V.; Yudin, A. K. J. Am. Chem. Soc. 2010, 132, 2889. doi:10.1021/ja910544p
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 2889
-
-
Hili, R.1
Rai, V.2
Yudin, A.K.3
-
250
-
-
84879852157
-
-
doi:10.1039/c3md00054k
-
Chung, B. K. W.; Hickey, J. L.; Scully, C. C. G.; Zaretsky, S.; Yudin, A. K. Med. Chem. Commun. 2013, 4, 1124. doi:10.1039/c3md00054k
-
(2013)
Med. Chem. Commun.
, vol.4
, pp. 1124
-
-
Chung, B.K.W.1
Hickey, J.L.2
Scully, C.C.G.3
Zaretsky, S.4
Yudin, A.K.5
-
251
-
-
80054744507
-
-
doi:10.1002/chem.201102096
-
Rotstein, B. H.; Mourtada, R.; Kelley, S. O.; Yudin, A. K. Chem.-Eur. J. 2011, 17, 12257. doi:10.1002/chem.201102096
-
(2011)
Chem.-Eur. J.
, vol.17
, pp. 12257
-
-
Rotstein, B.H.1
Mourtada, R.2
Kelley, S.O.3
Yudin, A.K.4
-
252
-
-
84863905110
-
-
doi:10.1021/bc300239a
-
Roxin, A.; Chen, J.; Scully, C. C. G.; Rotstein, B. H.; Yudin, A. K.; Zheng, G. Bioconjugate Chem. 2012, 23, 1387. doi:10.1021/bc300239a
-
(2012)
Bioconjugate Chem.
, vol.23
, pp. 1387
-
-
Roxin, A.1
Chen, J.2
Scully, C.C.G.3
Rotstein, B.H.4
Yudin, A.K.5
Zheng, G.6
-
253
-
-
84890968755
-
-
doi:10.1002/chem.201303453
-
Zartetsky, S.; Scully, C. C. G.; Lough, A. J.; Yudin, A. K. Chem.-Eur. J. 2013, 19, 17668. doi:10.1002/chem.201303453
-
(2013)
Chem.-Eur. J.
, vol.19
, pp. 17668
-
-
Zartetsky, S.1
Scully, C.C.G.2
Lough, A.J.3
Yudin, A.K.4
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