The solution phase synthesis of diketopiperazine libraries via the Ugi reaction: Novel application of Armstrong's convertible isonitrile.

Tetrahedron Letters

Volumn 39, Issue 10, 1998, Pages 1113-1116

  Hulme, Christopher ^a   Morrissette, Matthew M ^a   Volz, Francis A ^a   Burns, Christopher J ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PIPERAZINEDIONE;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; LIBRARY; REACTION ANALYSIS; SYNTHESIS;

EID: 0032485439     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10795-X     Document Type: Article

References (25)

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19. 10. Performed in a SAVANT® evaporator for 2 hours.
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22. 3CN to 100% over 5 min. HPLC was interfaced with APCI techniques.
23. 2 combination as described in the text of this letter.
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25. (equation presented) 16. 2,2-Cyclopropane glycine input -