Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 7, 2008, Pages 2385-2389

  Kang, Suk Youn ^a   Lee, Sung Han ^a   Seo, Hee Jeong ^a   Jung, Myung Eun ^a   Ahn, Kwangwoo ^a   Kim, Jeongmin ^a   Lee, Jinhwa ^a  

^a Green Cross Company   (South Korea)

Author keywords

Anti obesity; Cannabinoid receptor antagonist; Rimonabant; Tetrazole

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR ANTAGONIST; CANNABINOID RECEPTOR; CYCLOPENTYLTETRAZOLE; PYRAZOLE DERIVATIVE; RIMONABANT; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BIOASSAY; CONTROLLED STUDY; DRUG DESIGN; DRUG DETERMINATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; FEMALE; IN VITRO STUDY; NONHUMAN; PHARMACOPHORE;

ANTI-OBESITY AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING, COMPETITIVE; LIGANDS; MODELS, CHEMICAL; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLES;

EID: 41149148300     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.02.061     Document Type: Article

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