Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 12, 2005, Pages 3086-3090

  Sperka, Tamás ^a   Pitlik, János ^b   Bagossi, Péter ^a   Tözsér, József ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Beta lactam library; Enzyme kinetics; HIV protease; Inhibition

Indexed keywords

ANTIVIRUS AGENT; BETA LACTAM DERIVATIVE; PROTEINASE INHIBITOR; VIRUS ENZYME;

ARTICLE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN;

ANIMALS; BETA-LACTAMS; BINDING, COMPETITIVE; COMBINATORIAL CHEMISTRY TECHNIQUES; DIMERIZATION; DRUG DESIGN; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; LEUKEMIA VIRUS, MURINE; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDE LIBRARY; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 19944402503     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.04.020     Document Type: Article

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