Synthesis of pseudopeptidic (S)-6-amino-5-oxo-1,4-diazepines and (S)-3-benzyl-2-oxo-1,4-benzodiazepines by an Ugi 4CC Staudinger/aza-Wittig sequence

Tetrahedron

Volumn 66, Issue 34, 2010, Pages 6783-6788

  Lecinska, Paulina ^a   Corres, Nazaret ^a   Moreno, Daniel ^a   García Valverde, María ^a   Marcaccini, Stefano ^b   Torroba, Tomás ^a  

^a UNIVERSITY OF BURGOS   (Spain)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Benzodiazepine; Diazepine; Isocyanide; Staudinger aza Wittig; Ugi reaction

Indexed keywords

3 BENZYL 2 OXO 1,4 BENZODIAZEPINE DERIVATIVE; 6 AMINO 5 OXO 1,4 DIAZEPINE DERIVATIVE; DIAZEPINE DERIVATIVE; N CYCLOHEXYL 2 (3 BENZYL 2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 1 YL) 2 (4 BROMOPHENYL)ACETAMIDE; N CYCLOHEXYL 2 (3 BENZYL 2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 1 YL) 2 (4 CHLOROPHENYL)ACETAMIDE; N CYCLOHEXYL 2 (3 BENZYL 2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 1 YL) 2 (4 METHYLPHENYL)ACETAMIDE; N CYCLOHEXYL 2 (3 BENZYL 2 OXO 5 PHENYL 2,3 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 1 YL) 2 ARYLACETAMIDE DERIVATIVE; N CYCLOHEXYL 2 [N (4 METHYLBENZYL) N (3 AZIDO 2 METHYLPROPIONYL)AMINO] 3 OXO 3 PHENYLPROPIONAMIDE; N CYCLOHEXYL 2 N 2 AZIDO 3 PHENYLPROPIONYL N (2 BENZOYLPHENYL) 2 (4 BROMOPHENYL)ACETAMIDE; N CYCLOHEXYL 4 (4 CHLOROBENZYL) 2 (4 METHOXYPHENYL) 5 OXO 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 (4 CHLOROBENZYL) 2 PHENYL 5 OXO 6 (TERT BUTOXYCARBONYLAMINO) 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 (4 FLUOROBENZYL) 2 PHENYL 5 OXO 6 METHYL 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 (4 METHOXYBENZYL) 2 (4 FLUOROPHENYL) 5 OXO 6 (TERT BUTOXYCARBONYLAMINO) 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 (4 METHOXYBENZYL) 2 (4 TRIFLUOROMETHYLPHENYL) 5 OXO 6 (TERT BUTOXYCARBONYLAMINO) 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 (4 METHYLBENZYL) 2 PHENYL 5 OXO 6 METHYL 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 ALKYL 2 ARYL 5 OXO 6 (TERT BUTOXYCARBONYLAMINO) 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE DERIVATIVE; N CYCLOHEXYL 4 BENZYL 2 (4 FLUOROPHENYL) 5 OXO 4,5,6,7 TETRAHYDRO 1H 1,4 DIAZEPINE 3 CARBOXAMIDE; N CYCLOHEXYL 4 N BUTYL 2 PHENYL 5 OXO 6 (TERT BUTOXYCARBONYLAMINO) 4,5,6,7 TETRAHYDRO 1H ,4 DIAZEPINE 3 CARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STAUDINGER REACTION; SYNTHESIS; WITTIG REACTION;

HUMAN ECHOVIRUS 1;

EID: 77955470708     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.06.062     Document Type: Article

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