Library synthesis and screening: 2,4-Diphenylthiazoles and 2,4-diphenyloxazoles as potential novel prion disease therapeutics

Journal of Medicinal Chemistry

Volumn 50, Issue 6, 2007, Pages 1347-1353

  Heal, William ^a   Thompson, Mark J ^a   Mutter, Roger ^a   Cope, Hannah ^a   Louth, Jenny C ^a   Chen, Beining ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 N BENZOYLPHENYLGLYCINONITRILE; 2,4 DIPHENYLOXAZOL 5 YLAMINE DERIVATIVE; 2,4 DIPHENYLTHIAZOL 5 YLAMINE DERIVATIVE; AMINOACETONITRILE; OXAZOLE DERIVATIVE; PHOSGENE; PRION PROTEIN; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CYCLIZATION; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; NONHUMAN; PRION DISEASE; SURFACE PLASMON RESONANCE;

ANIMALS; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; MICE; OXAZOLES; PRION DISEASES; PROTEIN BINDING; PRPC PROTEINS; PRPSC PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE; THIAZOLES;

EID: 33947614011     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0612719     Document Type: Article

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