Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel

Nature

Volumn 438, Issue 7065, 2005, Pages 248-252

  Lummis, Sarah C R ^a   Beene, Darren L ^b   Lee, Lori W ^b   Lester, Henry A ^c   Broadhurst, R William ^a   Dougherty, Dennis A ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b California Institute of Technology   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; CONFORMATIONS; ENERGY GAP; ISOMERIZATION; MUTAGENS; NEUROLOGY; POLYPEPTIDES;

CONFORMERS; MOLECULAR REARRANGEMENT; NEUROTRANSMITTER BINDING; PROLINE;

PROTEINS;

AMINO ACID; ION CHANNEL; MUTANT PROTEIN; NEUROTRANSMITTER; PROLINE; RECEPTOR PROTEIN; SEROTONIN RECEPTOR;

NEUROLOGY;

ARTICLE; BINDING SITE; ENERGY TRANSFER; ISOMERIZATION; MUTAGENESIS; NEUROTRANSMISSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

EID: 27744608733     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04130     Document Type: Article

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