Simultaneous assembly of the β-lactam and thiazole moiety by a new multicomponent reaction

Tetrahedron Letters

Volumn 43, Issue 39, 2002, Pages 6897-6901

  Kolb, Jürgen ^a   Beck, Barbara ^b   Dömling, Alexander ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Biovertis AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 DIMETHYLAMINO 2 ISOCYANOACYLATE; ALDEHYDE DERIVATIVE; BETA LACTAM; CARBOXYLIC ACID DERIVATIVE; ISOCYANIC ACID DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; MULTICOMPONENT REACTION; RING OPENING;

EID: 0037163321     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01621-0     Document Type: Article

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14. Actual examples of new MCRs: (a) Hulme, C.; Ma, L.; Romano, J. J.; Morton, G.; Tang, S.-Y.; Cherrier, M. P.; Choi, S.; Salvino, J.; Labaudiniere, R. Tetrahedron Lett. 2000, 41, 1889; (b) Lee, D.; Sello, J. K.; Schreiber, S. L. Org. Lett. 2000, 2, 709-712; (c) Sisko, J.; Kassick, A. J.; Mellinger, M.; Filan, J. J.; Allen, A.; Olsen, M. A. J. Org. Chem. 2000, 65, 1516; (d) Nair, L. G.; Fraser-Reid, B.; Szardenings, A. K. Org. Lett. 2001, 3, 317; (e) Ballini, R.; Bosica, G.; Conforti, M. L.; Maggi, R.; Mazzacani, A.; Righi, P.; Sartori, G. Tetrahedron Lett. 2001, 57, 1395; (f) Petasis, N. A.; Patel, Z. D. Tetrahedron Lett. 2000, 41, 9607; (g) Sun, X.; Javier, P.; Zhao, G.; Bienaymé, H.; Zu, J. Org. Lett. 2001, 3, 877; (h) Ross, G.; Ugi, I. Can. J. Chem. 2002, 79, 1.
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