Synthesis of conformationally constrained tricyclic β-lactam enantiomers through Ugi four-center three-component reactions of a monoterpene-based β-amino acid

Molecular Diversity

Volumn 14, Issue 1, 2010, Pages 59-65

  Szakonyi, Zsolt ^a   Sillanpää, Reijo ^b   Fülöp, Ferenc ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF JYVÄSKYLÄ   (Finland)

Author keywords

Amino acid; Chiral lactams; Multicomponent reaction; Solvent free; Stereoselective; Ugi reaction

Indexed keywords

2 AMINO 6,6 DIMETHYLBICYCLO[3.1.1]HEPTANE 3 CARBOXYLIC ACID; ALDEHYDE DERIVATIVE; BETA AMINO ACID; BETA LACTAM DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; N BENZYL 2 PHENYL 2 (8,8 DIMETHYL 4 OXO 3 AZATRICYCLO[5.1.1.0 2,5]NON 3 YL)ACETAMIDE; N BENZYL 3,3 DIMETHYL 2 (8,8 DIMETHYL 4 OXO 3 AZATRICYCLO[5.1.1.0 2,5]NON 3 YL)BUTYRAMIDE; N TERT BUTYL 2 (8,8 DIMETHYL 4 OXO 3 AZATRICYCLO[5.1.1.0 2,5]NON 3 YL)BUTYRAMIDE; N TERT BUTYL 2 PHENYL 2 (8,8 DIMETHYL 4 OXO 3 AZATRICYCLO[5.1.1.0 2,5]NON 3 YL)ACETAMIDE; N TERT BUTYL 3,3 DIMETHYL 2 (8,8 DIMETHYL 4 OXO 3 AZATRICYCLO[5.1.1.0 2,5]NON 3 YL)BUTYRAMIDE; PIVALALDEHYDE; PROPIONALDEHYDE; TERPENE; TRIBACTAM; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DIASTEREOISOMER; DRUG CONFORMATION; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL; REACTION TIME; STEREOCHEMISTRY;

AMINO ACIDS; BETA-LACTAMS; COMBINATORIAL CHEMISTRY TECHNIQUES; METHANOL; MONOTERPENES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEREOISOMERISM; WATER;

EID: 77149162419     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-009-9143-y     Document Type: Article

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