메뉴 건너뛰기




Volumn 306, Issue , 2013, Pages 223-273

New insights into the role of BubR1 in mitosis and beyond

Author keywords

Aneuploidy; BubR1; Checkpoints; Kinetochore; Meiosis; Microtubules; Mitosis

Indexed keywords

AURORA B KINASE; BRCA2 PROTEIN; BUB1 RELATED PROTEIN; BUB3 PROTEIN; CELL CYCLE PROTEIN 20; HISTONE ACETYLTRANSFERASE PCAF; NDC80 COMPLEX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN MAD1; PROTEIN MAD2; PROTEIN P53;

EID: 84883526960     PISSN: 19376448     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-407694-5.00006-7     Document Type: Chapter
Times cited : (34)

References (198)
  • 1
    • 0034664766 scopus 로고    scopus 로고
    • CENP-E as an essential component of the mitotic checkpoint in vitro
    • Abrieu A., Kahana J.A., Wood K.W., Cleveland D.W. CENP-E as an essential component of the mitotic checkpoint in vitro. Cell 2000, 102:817-826.
    • (2000) Cell , vol.102 , pp. 817-826
    • Abrieu, A.1    Kahana, J.A.2    Wood, K.W.3    Cleveland, D.W.4
  • 2
    • 77949618175 scopus 로고    scopus 로고
    • High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer
    • Ando K., Kakeji Y., Kitao H., Iimori M., Zhao Y., et al. High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer. Cancer Sci. 2010, 101:639-645.
    • (2010) Cancer Sci. , vol.101 , pp. 639-645
    • Ando, K.1    Kakeji, Y.2    Kitao, H.3    Iimori, M.4    Zhao, Y.5
  • 4
    • 3042761646 scopus 로고    scopus 로고
    • BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
    • Baker D.J., Jeganathan K.B., Cameron J.D., Thompson M., Juneja S., et al. BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat. Genet. 2004, 36:744-749.
    • (2004) Nat. Genet. , vol.36 , pp. 744-749
    • Baker, D.J.1    Jeganathan, K.B.2    Cameron, J.D.3    Thompson, M.4    Juneja, S.5
  • 5
    • 0032441970 scopus 로고    scopus 로고
    • Localization of the Drosophila checkpoint control protein Bub3 to the kinetochore requires Bub1 but not Zw10 or Rod
    • Basu J., Logarinho E., Herrmann S., Bousbaa H., Li Z., et al. Localization of the Drosophila checkpoint control protein Bub3 to the kinetochore requires Bub1 but not Zw10 or Rod. Chromosoma 1998, 107:376-385.
    • (1998) Chromosoma , vol.107 , pp. 376-385
    • Basu, J.1    Logarinho, E.2    Herrmann, S.3    Bousbaa, H.4    Li, Z.5
  • 6
    • 80053991470 scopus 로고    scopus 로고
    • The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression
    • Bie L., Zhao G., Cheng P., Rondeau G., Porwollik S., et al. The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression. PLoS One 2011, 6:e25631.
    • (2011) PLoS One , vol.6
    • Bie, L.1    Zhao, G.2    Cheng, P.3    Rondeau, G.4    Porwollik, S.5
  • 7
    • 80855128195 scopus 로고    scopus 로고
    • Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding site
    • Bolanos-Garcia V.M., Lischetti T., Matak-Vinkovic D., Cota E., Simpson P.J., et al. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding site. Structure 2011, 19:1691-1700.
    • (2011) Structure , vol.19 , pp. 1691-1700
    • Bolanos-Garcia, V.M.1    Lischetti, T.2    Matak-Vinkovic, D.3    Cota, E.4    Simpson, P.J.5
  • 8
    • 33947731702 scopus 로고    scopus 로고
    • Bub1 is essential for assembly of the functional inner centromere
    • Boyarchuk Y., Salic A., Dasso M., Arnaoutov A. Bub1 is essential for assembly of the functional inner centromere. J. Cell Biol. 2007, 176:919-928.
    • (2007) J. Cell Biol. , vol.176 , pp. 919-928
    • Boyarchuk, Y.1    Salic, A.2    Dasso, M.3    Arnaoutov, A.4
  • 9
    • 0242467431 scopus 로고    scopus 로고
    • Functionality of the spindle checkpoint during the first meiotic division of mammalian oocytes
    • Brunet S., Pahlavan G., Taylor S., Maro B. Functionality of the spindle checkpoint during the first meiotic division of mammalian oocytes. Reproduction 2003, 126:443-450.
    • (2003) Reproduction , vol.126 , pp. 443-450
    • Brunet, S.1    Pahlavan, G.2    Taylor, S.3    Maro, B.4
  • 10
    • 18844449387 scopus 로고    scopus 로고
    • Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex
    • Buffin E., Lefebvre C., Huang J., Gagou M.E., Karess R.E. Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex. Curr. Biol. 2005, 15:856-861.
    • (2005) Curr. Biol. , vol.15 , pp. 856-861
    • Buffin, E.1    Lefebvre, C.2    Huang, J.3    Gagou, M.E.4    Karess, R.E.5
  • 12
    • 33947310066 scopus 로고    scopus 로고
    • Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint
    • Burton J.L., Solomon M.J. Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev. 2007, 21:655-667.
    • (2007) Genes Dev. , vol.21 , pp. 655-667
    • Burton, J.L.1    Solomon, M.J.2
  • 13
    • 37049039447 scopus 로고    scopus 로고
    • Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis
    • Burum-Auensen E., DeAngelis P.M., Schjølberg A.R., Røislien J., Andersen S.N., Clausen O.P.F. Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis. J. Clin. Pathol. 2007, 60:1403-1408.
    • (2007) J. Clin. Pathol. , vol.60 , pp. 1403-1408
    • Burum-Auensen, E.1    DeAngelis, P.M.2    Schjølberg, A.R.3    Røislien, J.4    Andersen, S.N.5    Clausen, O.P.F.6
  • 14
    • 0032546360 scopus 로고    scopus 로고
    • Mutations of mitotic checkpoint genes in human cancers
    • Cahill D.P., Lengauer C., Yu J., Riggins G.J., Willson J.K., et al. Mutations of mitotic checkpoint genes in human cancers. Nature 1998, 392:300-303.
    • (1998) Nature , vol.392 , pp. 300-303
    • Cahill, D.P.1    Lengauer, C.2    Yu, J.3    Riggins, G.J.4    Willson, J.K.5
  • 15
    • 33646409883 scopus 로고    scopus 로고
    • BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance
    • Chabalier C., Lamare C., Racca C., Privat M., Valette A., Larminat F. BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. Cell Cycle 2006, 5:1001-1007.
    • (2006) Cell Cycle , vol.5 , pp. 1001-1007
    • Chabalier, C.1    Lamare, C.2    Racca, C.3    Privat, M.4    Valette, A.5    Larminat, F.6
  • 16
    • 0032487444 scopus 로고    scopus 로고
    • Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1
    • Chan G.K., Schaar B.T., Yen T.J. Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J. Cell Biol. 1998, 143:49-63.
    • (1998) J. Cell Biol. , vol.143 , pp. 49-63
    • Chan, G.K.1    Schaar, B.T.2    Yen, T.J.3
  • 17
    • 0032846338 scopus 로고    scopus 로고
    • Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC
    • Chan G.K., Jablonski S.A., Sudakin V., Hittle J.C., Yen T.J. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J. Cell Biol. 1999, 146:941-954.
    • (1999) J. Cell Biol. , vol.146 , pp. 941-954
    • Chan, G.K.1    Jablonski, S.A.2    Sudakin, V.3    Hittle, J.C.4    Yen, T.J.5
  • 18
    • 10344234720 scopus 로고    scopus 로고
    • Poly(ADP-ribose) is required for spindle assembly and structure
    • Chang P., Jacobson M.K., Mitchison T.J. Poly(ADP-ribose) is required for spindle assembly and structure. Nature 2004, 432:645-649.
    • (2004) Nature , vol.432 , pp. 645-649
    • Chang, P.1    Jacobson, M.K.2    Mitchison, T.J.3
  • 20
    • 33751232957 scopus 로고    scopus 로고
    • The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
    • Cheeseman I.M., Chappie J.S., Wilson-Kubalek E.M., Desai A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 2006, 127:983-997.
    • (2006) Cell , vol.127 , pp. 983-997
    • Cheeseman, I.M.1    Chappie, J.S.2    Wilson-Kubalek, E.M.3    Desai, A.4
  • 21
    • 0036322225 scopus 로고    scopus 로고
    • BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
    • Chen R.H. BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1. J. Cell Biol. 2002, 158:487-496.
    • (2002) J. Cell Biol. , vol.158 , pp. 487-496
    • Chen, R.H.1
  • 22
    • 67651161889 scopus 로고    scopus 로고
    • BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis
    • Choi E., Choe H., Min J., Choi J.Y., Kim J., Lee H. BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis. EMBO J. 2009, 28:2077-2089.
    • (2009) EMBO J. , vol.28 , pp. 2077-2089
    • Choi, E.1    Choe, H.2    Min, J.3    Choi, J.Y.4    Kim, J.5    Lee, H.6
  • 23
    • 84863073742 scopus 로고    scopus 로고
    • BRCA2 fine-tunes the spindle assembly checkpoint through reinforcement of BubR1 acetylation
    • Choi E., Park P.G., Lee H.O., Lee Y.K., Kang G.H., et al. BRCA2 fine-tunes the spindle assembly checkpoint through reinforcement of BubR1 acetylation. Dev. Cell 2012, 22:295-308.
    • (2012) Dev. Cell , vol.22 , pp. 295-308
    • Choi, E.1    Park, P.G.2    Lee, H.O.3    Lee, Y.K.4    Kang, G.H.5
  • 24
    • 79954614831 scopus 로고    scopus 로고
    • The role of shugoshin in meiotic chromosome segregation
    • Clift D., Marston A.L. The role of shugoshin in meiotic chromosome segregation. Cytogenet. Genome Res. 2011, 133:234-242.
    • (2011) Cytogenet. Genome Res. , vol.133 , pp. 234-242
    • Clift, D.1    Marston, A.L.2
  • 25
    • 0033145508 scopus 로고    scopus 로고
    • Temporal and spatial control of cyclin B1 destruction in metaphase
    • Clute P., Pines J. Temporal and spatial control of cyclin B1 destruction in metaphase. Nat. Cell Biol. 1999, 1:82-87.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 82-87
    • Clute, P.1    Pines, J.2
  • 26
    • 9144253124 scopus 로고    scopus 로고
    • Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency
    • Dai W., Wang Q., Liu T., Swamy M., Fang Y., et al. Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency. Cancer Res. 2004, 64:440-445.
    • (2004) Cancer Res. , vol.64 , pp. 440-445
    • Dai, W.1    Wang, Q.2    Liu, T.3    Swamy, M.4    Fang, Y.5
  • 27
  • 28
    • 77952007380 scopus 로고    scopus 로고
    • Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition
    • D'Arcy S., Davies O.R., Blundell T.L., Bolanos-Garcia V.M. Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition. J. Biol. Chem. 2010, 285:14764-14776.
    • (2010) J. Biol. Chem. , vol.285 , pp. 14764-14776
    • D'Arcy, S.1    Davies, O.R.2    Blundell, T.L.3    Bolanos-Garcia, V.M.4
  • 29
    • 33646851446 scopus 로고    scopus 로고
    • Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1
    • Davenport J., Harris L.D., Goorha R. Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1. Exp. Cell Res. 2006, 312:1831-1842.
    • (2006) Exp. Cell Res. , vol.312 , pp. 1831-1842
    • Davenport, J.1    Harris, L.D.2    Goorha, R.3
  • 30
    • 13444288299 scopus 로고    scopus 로고
    • The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
    • De Antoni A., Pearson C.G., Cimini D., Canman J.C., Sala V., et al. The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr. Biol. 2005, 15:214-225.
    • (2005) Curr. Biol. , vol.15 , pp. 214-225
    • De Antoni, A.1    Pearson, C.G.2    Cimini, D.3    Canman, J.C.4    Sala, V.5
  • 31
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: the protein complex that shapes and safeguards human telomeres
    • de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 2005, 19:2100-2110.
    • (2005) Genes Dev. , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 32
    • 84857685447 scopus 로고    scopus 로고
    • Structural organization of the kinetochore-microtubule interface
    • DeLuca J.G., Musacchio A. Structural organization of the kinetochore-microtubule interface. Curr. Opin. Cell Biol. 2011, 24:48-56.
    • (2011) Curr. Opin. Cell Biol. , vol.24 , pp. 48-56
    • DeLuca, J.G.1    Musacchio, A.2
  • 33
    • 33751227843 scopus 로고    scopus 로고
    • Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
    • DeLuca J.G., Gall W.E., Ciferri C., Cimini D., Musacchio A., Salmon E.D. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 2006, 127:969-982.
    • (2006) Cell , vol.127 , pp. 969-982
    • DeLuca, J.G.1    Gall, W.E.2    Ciferri, C.3    Cimini, D.4    Musacchio, A.5    Salmon, E.D.6
  • 34
    • 61449137784 scopus 로고    scopus 로고
    • Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival
    • de Reynies A., Assie G., Rickman D.S., Tissier F., Groussin L., et al. Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival. J. Clin. Oncol. 2009, 27:1108-1115.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 1108-1115
    • de Reynies, A.1    Assie, G.2    Rickman, D.S.3    Tissier, F.4    Groussin, L.5
  • 35
    • 55949096605 scopus 로고    scopus 로고
    • Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo
    • Diaz-Rodríguez E., Sotillo R., Schvartzman J.-M., Benezra R. Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:16719-16724.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 16719-16724
    • Diaz-Rodríguez, E.1    Sotillo, R.2    Schvartzman, J.-M.3    Benezra, R.4
  • 36
    • 0013057087 scopus 로고    scopus 로고
    • Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
    • Ditchfield C., Johnson V.L., Tighe A., Ellston R., Haworth C., et al. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J. Cell Biol. 2003, 161:267-280.
    • (2003) J. Cell Biol. , vol.161 , pp. 267-280
    • Ditchfield, C.1    Johnson, V.L.2    Tighe, A.3    Ellston, R.4    Haworth, C.5
  • 37
    • 84857685615 scopus 로고    scopus 로고
    • Kinetochore dynamics: how protein dynamics affect chromosome segregation
    • Dorn J.F., Maddox P.S. Kinetochore dynamics: how protein dynamics affect chromosome segregation. Curr. Opin. Cell Biol. 2012, 24:57-63.
    • (2012) Curr. Opin. Cell Biol. , vol.24 , pp. 57-63
    • Dorn, J.F.1    Maddox, P.S.2
  • 38
    • 33745542004 scopus 로고    scopus 로고
    • Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells
    • Draviam V.M., Shapiro I., Aldridge B., Sorger P.K. Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells. EMBO J. 2006, 25:2814-2827.
    • (2006) EMBO J. , vol.25 , pp. 2814-2827
    • Draviam, V.M.1    Shapiro, I.2    Aldridge, B.3    Sorger, P.K.4
  • 39
    • 34548436939 scopus 로고    scopus 로고
    • Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions
    • Elowe S., Hummer S., Uldschmid A., Li X., Nigg E.A. Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes Dev. 2007, 21:2205-2219.
    • (2007) Genes Dev. , vol.21 , pp. 2205-2219
    • Elowe, S.1    Hummer, S.2    Uldschmid, A.3    Li, X.4    Nigg, E.A.5
  • 40
    • 72449178000 scopus 로고    scopus 로고
    • Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1
    • Elowe S., Dulla K., Uldschmid A., Li X., Dou Z., Nigg E.A. Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J. Cell Sci. 2010, 123:84-94.
    • (2010) J. Cell Sci. , vol.123 , pp. 84-94
    • Elowe, S.1    Dulla, K.2    Uldschmid, A.3    Li, X.4    Dou, Z.5    Nigg, E.A.6
  • 41
    • 84859941751 scopus 로고    scopus 로고
    • Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore
    • Espeut J., Cheerambathur D.K., Krenning L., Oegema K., Desai A. Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. J. Cell Biol. 2012, 196:469-482.
    • (2012) J. Cell Biol. , vol.196 , pp. 469-482
    • Espeut, J.1    Cheerambathur, D.K.2    Krenning, L.3    Oegema, K.4    Desai, A.5
  • 42
    • 0036199862 scopus 로고    scopus 로고
    • Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
    • Fang G. Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex. Mol. Biol. Cell 2002, 13:755-766.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 755-766
    • Fang, G.1
  • 43
    • 33646540000 scopus 로고    scopus 로고
    • BubR1 is involved in regulation of DNA damage responses
    • Fang Y., Liu T., Wang X., Yang Y.M., Deng H., et al. BubR1 is involved in regulation of DNA damage responses. Oncogene 2006, 25:3598-3605.
    • (2006) Oncogene , vol.25 , pp. 3598-3605
    • Fang, Y.1    Liu, T.2    Wang, X.3    Yang, Y.M.4    Deng, H.5
  • 44
    • 61549131993 scopus 로고    scopus 로고
    • Ajuba: a new microtubule-associated protein that interacts with BUBR1 and Aurora B at kinetochores in metaphase
    • Ferrand A., Chevrier V., Chauvin J.P., Birnbaum D. Ajuba: a new microtubule-associated protein that interacts with BUBR1 and Aurora B at kinetochores in metaphase. Biol. Cell 2009, 101:221-235.
    • (2009) Biol. Cell , vol.101 , pp. 221-235
    • Ferrand, A.1    Chevrier, V.2    Chauvin, J.P.3    Birnbaum, D.4
  • 45
    • 84871530214 scopus 로고    scopus 로고
    • Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore
    • Foley E.A., Kapoor T.M. Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nat. Rev. Mol. Cell Biol. 2013, 14:25-37.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 25-37
    • Foley, E.A.1    Kapoor, T.M.2
  • 46
    • 80053573427 scopus 로고    scopus 로고
    • Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase
    • Foley E.A., Maldonado M., Kapoor T.M. Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase. Nat. Cell Biol. 2011, 13:1265-1271.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1265-1271
    • Foley, E.A.1    Maldonado, M.2    Kapoor, T.M.3
  • 47
    • 0035803404 scopus 로고    scopus 로고
    • Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores
    • Fraschini R., Beretta A., Sironi L., Musacchio A., Lucchini G., Piatti S. Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J. 2001, 20:6648-6659.
    • (2001) EMBO J. , vol.20 , pp. 6648-6659
    • Fraschini, R.1    Beretta, A.2    Sironi, L.3    Musacchio, A.4    Lucchini, G.5    Piatti, S.6
  • 48
    • 84861943203 scopus 로고    scopus 로고
    • The mammalian synaptonemal complex: protein components, assembly and role in meiotic recombination
    • Fraune J., Schramm S., Alsheimer M., Benavente R. The mammalian synaptonemal complex: protein components, assembly and role in meiotic recombination. Exp. Cell Res. 2012, 318:1340-1346.
    • (2012) Exp. Cell Res. , vol.318 , pp. 1340-1346
    • Fraune, J.1    Schramm, S.2    Alsheimer, M.3    Benavente, R.4
  • 49
    • 77449086261 scopus 로고    scopus 로고
    • Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours
    • Gladhaug I.P., Westgaard A., Schjolberg A.R., Burum-Auensen E., Pomianowska E., Clausen O.P. Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours. Histopathology 2010, 56:345-355.
    • (2010) Histopathology , vol.56 , pp. 345-355
    • Gladhaug, I.P.1    Westgaard, A.2    Schjolberg, A.R.3    Burum-Auensen, E.4    Pomianowska, E.5    Clausen, O.P.6
  • 50
    • 74249084585 scopus 로고    scopus 로고
    • The synaptonemal complex protein Zip1 promotes bi-orientation of centromeres at meiosis I
    • Gladstone M.N., Obeso D., Chuong H., Dawson D.S. The synaptonemal complex protein Zip1 promotes bi-orientation of centromeres at meiosis I. PLoS Genet. 2009, 5:e1000771.
    • (2009) PLoS Genet. , vol.5
    • Gladstone, M.N.1    Obeso, D.2    Chuong, H.3    Dawson, D.S.4
  • 51
    • 0037649987 scopus 로고    scopus 로고
    • Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer-association with tumour cell proliferation
    • Grabsch H., Takeno S., Parsons W.J., Pomjanski N., Boecking A., et al. Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer-association with tumour cell proliferation. J. Pathol. 2003, 200:16-22.
    • (2003) J. Pathol. , vol.200 , pp. 16-22
    • Grabsch, H.1    Takeno, S.2    Parsons, W.J.3    Pomjanski, N.4    Boecking, A.5
  • 52
    • 26244463198 scopus 로고    scopus 로고
    • APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment
    • Green R.A., Wollman R., Kaplan K.B. APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol. Biol. Cell 2005, 16:4609-4622.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4609-4622
    • Green, R.A.1    Wollman, R.2    Kaplan, K.B.3
  • 53
    • 80051551627 scopus 로고    scopus 로고
    • Reduced proliferation of aged human vascular smooth muscle cells-role of oxygen-derived free radicals and BubR1 expression
    • Guntani A., Matsumoto T., Kyuragi R., Iwasa K., Onohara T., et al. Reduced proliferation of aged human vascular smooth muscle cells-role of oxygen-derived free radicals and BubR1 expression. J. Surg. Res. 2011, 170:143-149.
    • (2011) J. Surg. Res. , vol.170 , pp. 143-149
    • Guntani, A.1    Matsumoto, T.2    Kyuragi, R.3    Iwasa, K.4    Onohara, T.5
  • 54
    • 84864980660 scopus 로고    scopus 로고
    • CENP-E-dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint
    • Guo Y., Kim C., Ahmad S., Zhang J., Mao Y. CENP-E-dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint. J. Cell Biol. 2012, 198:205-217.
    • (2012) J. Cell Biol. , vol.198 , pp. 205-217
    • Guo, Y.1    Kim, C.2    Ahmad, S.3    Zhang, J.4    Mao, Y.5
  • 55
    • 0345304252 scopus 로고    scopus 로고
    • Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1
    • Gupta A., Inaba S., Wong O.K., Fang G., Liu J. Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1. Oncogene 2003, 22:7593-7599.
    • (2003) Oncogene , vol.22 , pp. 7593-7599
    • Gupta, A.1    Inaba, S.2    Wong, O.K.3    Fang, G.4    Liu, J.5
  • 56
    • 34547614077 scopus 로고    scopus 로고
    • P53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation
    • Ha G.H., Baek K.H., Kim H.S., Jeong S.J., Kim C.M., et al. p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation. Cancer Res. 2007, 67:7155-7164.
    • (2007) Cancer Res. , vol.67 , pp. 7155-7164
    • Ha, G.H.1    Baek, K.H.2    Kim, H.S.3    Jeong, S.J.4    Kim, C.M.5
  • 57
    • 79956334631 scopus 로고    scopus 로고
    • Mps1 at kinetochores is essential for female mouse meiosis I
    • Hached K., Xie S.Z., Buffin E., Cladiere D., Rachez C., et al. Mps1 at kinetochores is essential for female mouse meiosis I. Development 2011, 138:2261-2271.
    • (2011) Development , vol.138 , pp. 2261-2271
    • Hached, K.1    Xie, S.Z.2    Buffin, E.3    Cladiere, D.4    Rachez, C.5
  • 58
    • 10644258336 scopus 로고    scopus 로고
    • Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
    • Hanks S., Coleman K., Reid S., Plaja A., Firth H., et al. Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat. Genet. 2004, 36:1159-1161.
    • (2004) Nat. Genet. , vol.36 , pp. 1159-1161
    • Hanks, S.1    Coleman, K.2    Reid, S.3    Plaja, A.4    Firth, H.5
  • 59
    • 0034611013 scopus 로고    scopus 로고
    • MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p
    • Hardwick K.G., Johnston R.C., Smith D.L., Murray A.W. MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J. Cell Biol. 2000, 148:871-882.
    • (2000) J. Cell Biol. , vol.148 , pp. 871-882
    • Hardwick, K.G.1    Johnston, R.C.2    Smith, D.L.3    Murray, A.W.4
  • 60
    • 22144443081 scopus 로고    scopus 로고
    • The mitotic checkpoint gene BubR1 has two distinct functions in mitosis
    • Harris L., Davenport J., Neale G., Goorha R. The mitotic checkpoint gene BubR1 has two distinct functions in mitosis. Exp. Cell Res. 2005, 308:85-100.
    • (2005) Exp. Cell Res. , vol.308 , pp. 85-100
    • Harris, L.1    Davenport, J.2    Neale, G.3    Goorha, R.4
  • 61
    • 0035951697 scopus 로고    scopus 로고
    • Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers
    • Haruki N., Saito H., Harano T., Nomoto S., Takahashi T., et al. Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers. Cancer Lett. 2001, 162:201-205.
    • (2001) Cancer Lett. , vol.162 , pp. 201-205
    • Haruki, N.1    Saito, H.2    Harano, T.3    Nomoto, S.4    Takahashi, T.5
  • 62
    • 0035319804 scopus 로고    scopus 로고
    • To err (meiotically) is human: the genesis of human aneuploidy
    • Hassold T., Hunt P. To err (meiotically) is human: the genesis of human aneuploidy. Nat. Rev. Genet. 2001, 2:280-291.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 280-291
    • Hassold, T.1    Hunt, P.2
  • 63
    • 0038746733 scopus 로고    scopus 로고
    • The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint
    • Hauf S., Cole R.W., LaTerra S., Zimmer C., Schnapp G., et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J. Cell Biol. 2003, 161:281-294.
    • (2003) J. Cell Biol. , vol.161 , pp. 281-294
    • Hauf, S.1    Cole, R.W.2    LaTerra, S.3    Zimmer, C.4    Schnapp, G.5
  • 64
    • 62449220573 scopus 로고    scopus 로고
    • Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex
    • Herzog F., Primorac I., Dube P., Lenart P., Sander B., et al. Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science 2009, 323:1477-1481.
    • (2009) Science , vol.323 , pp. 1477-1481
    • Herzog, F.1    Primorac, I.2    Dube, P.3    Lenart, P.4    Sander, B.5
  • 65
    • 0035153295 scopus 로고    scopus 로고
    • Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores
    • Hoffman D.B., Pearson C.G., Yen T.J., Howell B.J., Salmon E.D. Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores. Mol. Biol. Cell 2001, 12:1995-2009.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1995-2009
    • Hoffman, D.B.1    Pearson, C.G.2    Yen, T.J.3    Howell, B.J.4    Salmon, E.D.5
  • 66
    • 84867475385 scopus 로고    scopus 로고
    • APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing
    • Holt J.E., Lane S.I., Jennings P., Garcia-Higuera I., Moreno S., Jones K.T. APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing. Mol. Biol. Cell 2012, 23:3970-3981.
    • (2012) Mol. Biol. Cell , vol.23 , pp. 3970-3981
    • Holt, J.E.1    Lane, S.I.2    Jennings, P.3    Garcia-Higuera, I.4    Moreno, S.5    Jones, K.T.6
  • 67
    • 29244475389 scopus 로고    scopus 로고
    • Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes
    • Homer H.A., McDougall A., Levasseur M., Murdoch A.P., Herbert M. Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes. Reproduction 2005, 130:829-843.
    • (2005) Reproduction , vol.130 , pp. 829-843
    • Homer, H.A.1    McDougall, A.2    Levasseur, M.3    Murdoch, A.P.4    Herbert, M.5
  • 68
    • 72449159248 scopus 로고    scopus 로고
    • A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression
    • Homer H., Gui L., Carroll J. A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression. Science 2009, 326:991-994.
    • (2009) Science , vol.326 , pp. 991-994
    • Homer, H.1    Gui, L.2    Carroll, J.3
  • 69
    • 0035945356 scopus 로고    scopus 로고
    • Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
    • Howell B.J., McEwen B.F., Canman J.C., Hoffman D.B., Farrar E.M., et al. Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J. Cell Biol. 2001, 155:1159-1172.
    • (2001) J. Cell Biol. , vol.155 , pp. 1159-1172
    • Howell, B.J.1    McEwen, B.F.2    Canman, J.C.3    Hoffman, D.B.4    Farrar, E.M.5
  • 71
    • 58149196468 scopus 로고    scopus 로고
    • Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
    • Huang H., Hittle J., Zappacosta F., Annan R.S., Hershko A., Yen T.J. Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit. J. Cell Biol. 2008, 183:667-680.
    • (2008) J. Cell Biol. , vol.183 , pp. 667-680
    • Huang, H.1    Hittle, J.2    Zappacosta, F.3    Annan, R.S.4    Hershko, A.5    Yen, T.J.6
  • 72
    • 3242891383 scopus 로고    scopus 로고
    • PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development
    • Huber A., Bai P., de Murcia J.M., de Murcia G. PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development. DNA Repair (Amst.) 2004, 3:1103-1108.
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 1103-1108
    • Huber, A.1    Bai, P.2    de Murcia, J.M.3    de Murcia, G.4
  • 73
    • 68349155746 scopus 로고    scopus 로고
    • BubR1 localizes to centrosomes and suppresses centrosome amplification via regulating Plk1 activity in interphase cells
    • Izumi H., Matsumoto Y., Ikeuchi T., Saya H., Kajii T., Matsuura S. BubR1 localizes to centrosomes and suppresses centrosome amplification via regulating Plk1 activity in interphase cells. Oncogene 2009, 28:2806-2820.
    • (2009) Oncogene , vol.28 , pp. 2806-2820
    • Izumi, H.1    Matsumoto, Y.2    Ikeuchi, T.3    Saya, H.4    Kajii, T.5    Matsuura, S.6
  • 74
    • 0032415592 scopus 로고    scopus 로고
    • The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis
    • Jablonski S.A., Chan G.K., Cooke C.A., Earnshaw W.C., Yen T.J. The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis. Chromosoma 1998, 107:386-396.
    • (1998) Chromosoma , vol.107 , pp. 386-396
    • Jablonski, S.A.1    Chan, G.K.2    Cooke, C.A.3    Earnshaw, W.C.4    Yen, T.J.5
  • 75
    • 2342439525 scopus 로고    scopus 로고
    • Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
    • Johnson V.L., Scott M.I., Holt S.V., Hussein D., Taylor S.S. Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. J. Cell Sci. 2004, 117:1577-1589.
    • (2004) J. Cell Sci. , vol.117 , pp. 1577-1589
    • Johnson, V.L.1    Scott, M.I.2    Holt, S.V.3    Hussein, D.4    Taylor, S.S.5
  • 76
    • 0037018844 scopus 로고    scopus 로고
    • Inhibition of Aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis
    • Kallio M.J., McCleland M.L., Stukenberg P.T., Gorbsky G.J. Inhibition of Aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr. Biol. 2002, 12:900-905.
    • (2002) Curr. Biol. , vol.12 , pp. 900-905
    • Kallio, M.J.1    McCleland, M.L.2    Stukenberg, P.T.3    Gorbsky, G.J.4
  • 77
    • 44449120297 scopus 로고    scopus 로고
    • HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint
    • Kim S., Park S.Y., Yong H., Famulski J.K., Chae S., et al. HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint. Oncogene 2008, 27:3457-3464.
    • (2008) Oncogene , vol.27 , pp. 3457-3464
    • Kim, S.1    Park, S.Y.2    Yong, H.3    Famulski, J.K.4    Chae, S.5
  • 78
    • 56149107126 scopus 로고    scopus 로고
    • KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint
    • King E.M., van der Sar S.J., Hardwick K.G. Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint. PLoS One 2007, 2:e342.
    • (2007) PLoS One , vol.2
    • King, E.M.1    Van Der Sar, S.J.2    Hardwick, K.G.3
  • 79
    • 35649019314 scopus 로고    scopus 로고
    • Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1
    • Kiyomitsu T., Obuse C., Yanagida M. Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. Dev. Cell 2007, 13:663-676.
    • (2007) Dev. Cell , vol.13 , pp. 663-676
    • Kiyomitsu, T.1    Obuse, C.2    Yanagida, M.3
  • 80
    • 79952269227 scopus 로고    scopus 로고
    • Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1
    • Kiyomitsu T., Murakami H., Yanagida M. Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1. Mol. Cell Biol. 2011, 31:998-1011.
    • (2011) Mol. Cell Biol. , vol.31 , pp. 998-1011
    • Kiyomitsu, T.1    Murakami, H.2    Yanagida, M.3
  • 81
    • 1542373746 scopus 로고    scopus 로고
    • Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments
    • Kline-Smith S.L., Khodjakov A., Hergert P., Walczak C.E. Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments. Mol. Biol. Cell 2004, 15:1146-1159.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1146-1159
    • Kline-Smith, S.L.1    Khodjakov, A.2    Hergert, P.3    Walczak, C.E.4
  • 82
    • 33750609316 scopus 로고    scopus 로고
    • Aurora B is enriched at merotelic attachment sites, where it regulates MCAK
    • Knowlton A.L., Lan W., Stukenberg P.T. Aurora B is enriched at merotelic attachment sites, where it regulates MCAK. Curr. Biol. 2006, 16:1705-1710.
    • (2006) Curr. Biol. , vol.16 , pp. 1705-1710
    • Knowlton, A.L.1    Lan, W.2    Stukenberg, P.T.3
  • 83
    • 84867627900 scopus 로고    scopus 로고
    • Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint
    • Kops G.J., Shah J.V. Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint. Chromosoma 2012, 121:509-525.
    • (2012) Chromosoma , vol.121 , pp. 509-525
    • Kops, G.J.1    Shah, J.V.2
  • 84
    • 2942567685 scopus 로고    scopus 로고
    • Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
    • Kops G.J., Foltz D.R., Cleveland D.W. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:8699-8704.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 8699-8704
    • Kops, G.J.1    Foltz, D.R.2    Cleveland, D.W.3
  • 85
    • 84859983402 scopus 로고    scopus 로고
    • Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction
    • Krenn V., Wehenkel A., Li X., Santaguida S., Musacchio A. Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction. J. Cell Biol. 2012, 196:451-467.
    • (2012) J. Cell Biol. , vol.196 , pp. 451-467
    • Krenn, V.1    Wehenkel, A.2    Li, X.3    Santaguida, S.4    Musacchio, A.5
  • 86
    • 84877912076 scopus 로고    scopus 로고
    • Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression
    • Kruse T., Zhang G., Larsen M.S., Lischetti T., Streicher W., et al. Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression. J. Cell Sci. 2013, 126:1086-1092.
    • (2013) J. Cell Sci. , vol.126 , pp. 1086-1092
    • Kruse, T.1    Zhang, G.2    Larsen, M.S.3    Lischetti, T.4    Streicher, W.5
  • 87
    • 58149466576 scopus 로고    scopus 로고
    • Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
    • Kulukian A., Han J.S., Cleveland D.W. Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding. Dev. Cell 2009, 16:105-117.
    • (2009) Dev. Cell , vol.16 , pp. 105-117
    • Kulukian, A.1    Han, J.S.2    Cleveland, D.W.3
  • 88
    • 79952107079 scopus 로고    scopus 로고
    • Sensing centromere tension: Aurora B and the regulation of kinetochore function
    • Lampson M.A., Cheeseman I.M. Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol. 2011, 21:133-140.
    • (2011) Trends Cell Biol. , vol.21 , pp. 133-140
    • Lampson, M.A.1    Cheeseman, I.M.2
  • 89
    • 12344266713 scopus 로고    scopus 로고
    • The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments
    • Lampson M.A., Kapoor,T.M., 2005. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat. Cell Biol. 2005, 7:93-98.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 93-98
    • Lampson, M.A.1    Kapoor, T.M.2
  • 90
    • 1542290607 scopus 로고    scopus 로고
    • Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity
    • Lan W., Zhang X., Kline-Smith S.L., Rosasco S.E., Barrett-Wilt G.A., et al. Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr. Biol. 2004, 14:273-286.
    • (2004) Curr. Biol.
    • Lan, W.1    Zhang, X.2    Kline-Smith, S.L.3    Rosasco, S.E.4    Barrett-Wilt, G.A.5
  • 91
    • 84856905741 scopus 로고    scopus 로고
    • BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner
    • Lara-Gonzalez, P., Scott M.I., Diez M., Sen O., Taylor S.S. BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner. J. Cell Sci. 2011, 124:4332-4345.
    • (2011) J. Cell Sci. , vol.124 , pp. 4332-4345
    • Lara-Gonzalez, P.1    Scott, M.I.2    Diez, M.3    Sen, O.4    Taylor, S.S.5
  • 94
    • 75149141361 scopus 로고    scopus 로고
    • Cross-talk between BubR1 expression and the commitment to differentiate in adipose-derived mesenchymal stem cells
    • Lee J., Lee C.G., Lee K.W., Lee C.W. Cross-talk between BubR1 expression and the commitment to differentiate in adipose-derived mesenchymal stem cells. Exp. Mol. Med. 2009, 41:873-879.
    • (2009) Exp. Mol. Med. , vol.41 , pp. 873-879
    • Lee, J.1    Lee, C.G.2    Lee, K.W.3    Lee, C.W.4
  • 95
    • 68149164763 scopus 로고    scopus 로고
    • BubR1 as a prognostic marker for recurrence-free survival rates in epithelial ovarian cancers
    • Lee Y.K., Choi E., Kim M.A., Park P.G., Park N.H., Lee H. BubR1 as a prognostic marker for recurrence-free survival rates in epithelial ovarian cancers. Br. J. Cancer 2009, 101:504-510.
    • (2009) Br. J. Cancer , vol.101 , pp. 504-510
    • Lee, Y.K.1    Choi, E.2    Kim, M.A.3    Park, P.G.4    Park, N.H.5    Lee, H.6
  • 96
    • 0038376119 scopus 로고    scopus 로고
    • Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension
    • Lens S.M., Wolthuis R.M., Klompmaker R., Kauw J., Agami R., et al. Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J. 2003, 22:2934-2947.
    • (2003) EMBO J. , vol.22 , pp. 2934-2947
    • Lens, S.M.1    Wolthuis, R.M.2    Klompmaker, R.3    Kauw, J.4    Agami, R.5
  • 97
    • 0028872743 scopus 로고
    • Mitotic forces control a cell-cycle checkpoint
    • Li X., Nicklas R.B. Mitotic forces control a cell-cycle checkpoint. Nature 1995, 373:630-632.
    • (1995) Nature , vol.373 , pp. 630-632
    • Li, X.1    Nicklas, R.B.2
  • 98
    • 70449433050 scopus 로고    scopus 로고
    • Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis
    • Li M., Li S., Yuan J., Wang Z.B., Sun S.C., et al. Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis. PLoS One 2009, 4:e7701.
    • (2009) PLoS One , vol.4
    • Li, M.1    Li, S.2    Yuan, J.3    Wang, Z.B.4    Sun, S.C.5
  • 99
    • 77949426000 scopus 로고    scopus 로고
    • BUBR1 expression in benign oral lesions and squamous cell carcinomas: correlation with human papillomavirus
    • Lira R.C., Miranda F.A., Guimaraes M.C., Simoes R.T., Donadi E.A., et al. BUBR1 expression in benign oral lesions and squamous cell carcinomas: correlation with human papillomavirus. Oncol. Rep. 2010, 23:1027-1036.
    • (2010) Oncol. Rep. , vol.23 , pp. 1027-1036
    • Lira, R.C.1    Miranda, F.A.2    Guimaraes, M.C.3    Simoes, R.T.4    Donadi, E.A.5
  • 100
    • 73349099718 scopus 로고    scopus 로고
    • The clinicopathological significance of BUBR1 overexpression in hepatocellular carcinoma
    • Liu A.W., Cai J., Zhao X.L., Xu A.M., Fu H.Q., et al. The clinicopathological significance of BUBR1 overexpression in hepatocellular carcinoma. J. Clin. Pathol. 2009, 62:1003-1008.
    • (2009) J. Clin. Pathol. , vol.62 , pp. 1003-1008
    • Liu, A.W.1    Cai, J.2    Zhao, X.L.3    Xu, A.M.4    Fu, H.Q.5
  • 101
    • 2342429609 scopus 로고    scopus 로고
    • Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells
    • Logarinho E., Bousbaa H., Dias J.M., Lopes C., Amorim I., et al. Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells. J. Cell Sci. 2004, 117:1757-1771.
    • (2004) J. Cell Sci. , vol.117 , pp. 1757-1771
    • Logarinho, E.1    Bousbaa, H.2    Dias, J.M.3    Lopes, C.4    Amorim, I.5
  • 102
    • 84861532305 scopus 로고    scopus 로고
    • Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores
    • London N., Ceto S., Ranish J.A., Biggins S. Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores. Curr. Biol. 2012, 22:900-906.
    • (2012) Curr. Biol. , vol.22 , pp. 900-906
    • London, N.1    Ceto, S.2    Ranish, J.A.3    Biggins, S.4
  • 103
    • 0242287930 scopus 로고    scopus 로고
    • Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways
    • Lydall D. Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways. J. Cell Sci. 2003, 116:4057-4065.
    • (2003) J. Cell Sci. , vol.116 , pp. 4057-4065
    • Lydall, D.1
  • 104
    • 77954706607 scopus 로고    scopus 로고
    • Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling
    • Maciejowski J., George K.A., Terret M.E., Zhang C., Shokat K.M., Jallepalli P.V. Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling. J. Cell Biol. 2010, 190:89-100.
    • (2010) J. Cell Biol. , vol.190 , pp. 89-100
    • Maciejowski, J.1    George, K.A.2    Terret, M.E.3    Zhang, C.4    Shokat, K.M.5    Jallepalli, P.V.6
  • 105
    • 34548282025 scopus 로고    scopus 로고
    • Drosophila BubR1 is essential for meiotic sister-chromatid cohesion and maintenance of synaptonemal complex
    • Malmanche N., Owen S., Gegick S., Steffensen S., Tomkiel J.E., Sunkel C.E. Drosophila BubR1 is essential for meiotic sister-chromatid cohesion and maintenance of synaptonemal complex. Curr. Biol. 2007, 17:1489-1497.
    • (2007) Curr. Biol. , vol.17 , pp. 1489-1497
    • Malmanche, N.1    Owen, S.2    Gegick, S.3    Steffensen, S.4    Tomkiel, J.E.5    Sunkel, C.E.6
  • 107
    • 0038446875 scopus 로고    scopus 로고
    • Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1
    • Mao Y., Abrieu A., Cleveland D.W. Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell 2003, 114:87-98.
    • (2003) Cell , vol.114 , pp. 87-98
    • Mao, Y.1    Abrieu, A.2    Cleveland, D.W.3
  • 108
    • 24944452696 scopus 로고    scopus 로고
    • Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling
    • Mao Y., Desai A., Cleveland D.W. Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. J. Cell Biol. 2005, 170:873-880.
    • (2005) J. Cell Biol. , vol.170 , pp. 873-880
    • Mao, Y.1    Desai, A.2    Cleveland, D.W.3
  • 109
    • 33645315214 scopus 로고    scopus 로고
    • Determinants of conformational dimerization of Mad2 and its inhibition by p31comet
    • Mapelli M., Filipp F.V., Rancati G., Massimiliano L., Nezi L., et al. Determinants of conformational dimerization of Mad2 and its inhibition by p31comet. EMBO J. 2006, 25:1273-1284.
    • (2006) EMBO J. , vol.25 , pp. 1273-1284
    • Mapelli, M.1    Filipp, F.V.2    Rancati, G.3    Massimiliano, L.4    Nezi, L.5
  • 110
    • 43149112331 scopus 로고    scopus 로고
    • Securin regulates entry into M-phase by modulating the stability of cyclin B
    • Marangos P., Carroll J. Securin regulates entry into M-phase by modulating the stability of cyclin B. Nat. Cell Biol. 2008, 10:445-451.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 445-451
    • Marangos, P.1    Carroll, J.2
  • 111
    • 33845994023 scopus 로고    scopus 로고
    • Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1)
    • Marangos P., Verschuren E.W., Chen R., Jackson P.K., Carroll J. Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). J. Cell Biol. 2007, 176:65-75.
    • (2007) J. Cell Biol. , vol.176 , pp. 65-75
    • Marangos, P.1    Verschuren, E.W.2    Chen, R.3    Jackson, P.K.4    Carroll, J.5
  • 112
    • 34447531017 scopus 로고    scopus 로고
    • Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1
    • Matsumura S., Toyoshima F., Nishida E. Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1. J. Biol. Chem. 2007, 282:15217-15227.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15217-15227
    • Matsumura, S.1    Toyoshima, F.2    Nishida, E.3
  • 113
    • 32444444090 scopus 로고    scopus 로고
    • Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome
    • Matsuura S., Matsumoto Y., Morishima K., Izumi H., Matsumoto H., et al. Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome. Am. J. Med. Genet. A 2006, 140:358-367.
    • (2006) Am. J. Med. Genet. A , vol.140 , pp. 358-367
    • Matsuura, S.1    Matsumoto, Y.2    Morishima, K.3    Izumi, H.4    Matsumoto, H.5
  • 114
    • 61449204992 scopus 로고    scopus 로고
    • Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint
    • McGuinness B.E., Anger M., Kouznetsova A., Gil-Bernabe A.M., Helmhart W., et al. Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Curr. Biol. 2009, 19:369-380.
    • (2009) Curr. Biol. , vol.19 , pp. 369-380
    • McGuinness, B.E.1    Anger, M.2    Kouznetsova, A.3    Gil-Bernabe, A.M.4    Helmhart, W.5
  • 115
    • 4344610852 scopus 로고    scopus 로고
    • Timing and checkpoints in the regulation of mitotic progression
    • Meraldi P., Draviam V.M., Sorger P.K. Timing and checkpoints in the regulation of mitotic progression. Dev. Cell 2004, 7:45-60.
    • (2004) Dev. Cell , vol.7 , pp. 45-60
    • Meraldi, P.1    Draviam, V.M.2    Sorger, P.K.3
  • 116
    • 0036210713 scopus 로고    scopus 로고
    • Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner
    • Millband D.N., Hardwick K.G. Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner. Mol. Cell Biol. 2002, 22:2728-2742.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 2728-2742
    • Millband, D.N.1    Hardwick, K.G.2
  • 117
    • 79955393977 scopus 로고    scopus 로고
    • Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates
    • Miyamoto T., Porazinski S., Wang H., Borovina A., Ciruna B., et al. Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates. Hum. Mol. Genet. 2011, 20:2058-2070.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 2058-2070
    • Miyamoto, T.1    Porazinski, S.2    Wang, H.3    Borovina, A.4    Ciruna, B.5
  • 118
    • 62849084852 scopus 로고    scopus 로고
    • TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis
    • Munoz P., Blanco R., de Carcer G., Schoeftner S., Benetti R., et al. TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis. Mol. Cell Biol. 2009, 29:1608-1625.
    • (2009) Mol. Cell Biol. , vol.29 , pp. 1608-1625
    • Munoz, P.1    Blanco, R.2    de Carcer, G.3    Schoeftner, S.4    Benetti, R.5
  • 119
    • 0037018843 scopus 로고    scopus 로고
    • The kinase activity of Aurora B is required for kinetochore-microtubule interactions during mitosis
    • Murata-Hori M., Wang Y.-L. The kinase activity of Aurora B is required for kinetochore-microtubule interactions during mitosis. Curr. Biol. 2002, 12:894-899.
    • (2002) Curr. Biol. , vol.12 , pp. 894-899
    • Murata-Hori, M.1    Wang, Y.-L.2
  • 120
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio A., Salmon E.D. The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 2007, 8:379-393.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 121
    • 39749181579 scopus 로고    scopus 로고
    • Unprotected Drosophila melanogaster telomeres activate the spindle assembly checkpoint
    • Musaro M., Ciapponi L., Fasulo B., Gatti M., Cenci G. Unprotected Drosophila melanogaster telomeres activate the spindle assembly checkpoint. Nat. Genet. 2008, 40:362-366.
    • (2008) Nat. Genet. , vol.40 , pp. 362-366
    • Musaro, M.1    Ciapponi, L.2    Fasulo, B.3    Gatti, M.4    Cenci, G.5
  • 122
    • 0034193627 scopus 로고    scopus 로고
    • Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines
    • Myrie K.A., Percy M.J., Azim J.N., Neeley C.K., Petty E.M. Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines. Cancer Lett. 2000, 152:193-199.
    • (2000) Cancer Lett. , vol.152 , pp. 193-199
    • Myrie, K.A.1    Percy, M.J.2    Azim, J.N.3    Neeley, C.K.4    Petty, E.M.5
  • 123
    • 77953291470 scopus 로고    scopus 로고
    • The LIM protein Ajuba is required for ciliogenesis and left-right axis determination in medaka
    • Nagai Y., Asaoka Y., Namae M., Saito K., Momose H., et al. The LIM protein Ajuba is required for ciliogenesis and left-right axis determination in medaka. Biochem. Biophys. Res. Commun. 2010, 396:887-893.
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 887-893
    • Nagai, Y.1    Asaoka, Y.2    Namae, M.3    Saito, K.4    Momose, H.5
  • 124
    • 84863892710 scopus 로고    scopus 로고
    • Human aneuploidy: mechanisms and new insights into an age-old problem
    • Nagaoka S.I., Hassold T.J., Hunt P.A. Human aneuploidy: mechanisms and new insights into an age-old problem. Nat. Rev. Genet. 2012, 13:493-504.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 493-504
    • Nagaoka, S.I.1    Hassold, T.J.2    Hunt, P.A.3
  • 125
    • 76249110367 scopus 로고    scopus 로고
    • The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I
    • Newnham L., Jordan P., Rockmill B., Roeder G.S., Hoffmann E. The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:781-785.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 781-785
    • Newnham, L.1    Jordan, P.2    Rockmill, B.3    Roeder, G.S.4    Hoffmann, E.5
  • 126
    • 39649117449 scopus 로고    scopus 로고
    • Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I
    • Niault T., Hached K., Sotillo R., Sorger P.K., Maro B., et al. Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I. PLoS One 2007, 2:e1165.
    • (2007) PLoS One , vol.2
    • Niault, T.1    Hached, K.2    Sotillo, R.3    Sorger, P.K.4    Maro, B.5
  • 127
    • 70350771277 scopus 로고    scopus 로고
    • Centrioles, centrosomes, and cilia in health and disease
    • Nigg E.A., Raff J.W. Centrioles, centrosomes, and cilia in health and disease. Cell 2009, 139:663-678.
    • (2009) Cell , vol.139 , pp. 663-678
    • Nigg, E.A.1    Raff, J.W.2
  • 128
    • 57049097535 scopus 로고    scopus 로고
    • The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
    • Nilsson J., Yekezare M., Minshull J., Pines J. The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. Nat. Cell Biol. 2008, 10:1411-1420.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1411-1420
    • Nilsson, J.1    Yekezare, M.2    Minshull, J.3    Pines, J.4
  • 129
    • 0034308209 scopus 로고    scopus 로고
    • Mutation analysis of mitotic checkpoint genes (hBUB1 and hBUBR1) and microsatellite instability in adult T-cell leukemia/lymphoma
    • Ohshima K., Haraoka S., Yoshioka S., Hamasaki M., Fujiki T., et al. Mutation analysis of mitotic checkpoint genes (hBUB1 and hBUBR1) and microsatellite instability in adult T-cell leukemia/lymphoma. Cancer Lett. 2000, 158:141-150.
    • (2000) Cancer Lett. , vol.158 , pp. 141-150
    • Ohshima, K.1    Haraoka, S.2    Yoshioka, S.3    Hamasaki, M.4    Fujiki, T.5
  • 130
    • 18144389836 scopus 로고    scopus 로고
    • Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1
    • Oikawa T., Okuda M., Ma Z., Goorha R., Tsujimoto H., et al. Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1. Mol. Cell Biol. 2005, 25:4046-4061.
    • (2005) Mol. Cell Biol. , vol.25 , pp. 4046-4061
    • Oikawa, T.1    Okuda, M.2    Ma, Z.3    Goorha, R.4    Tsujimoto, H.5
  • 131
    • 84868033744 scopus 로고    scopus 로고
    • Meiotic prophase requires proteolysis of M phase regulators mediated by the meiosis-specific APC/C-Ama1
    • Okaz E., Arguello-Miranda O., Bogdanova A., Vinod P.K., Lipp J.J., et al. Meiotic prophase requires proteolysis of M phase regulators mediated by the meiosis-specific APC/C-Ama1. Cell 2012, 151:603-618.
    • (2012) Cell , vol.151 , pp. 603-618
    • Okaz, E.1    Arguello-Miranda, O.2    Bogdanova, A.3    Vinod, P.K.4    Lipp, J.J.5
  • 132
    • 0035031228 scopus 로고    scopus 로고
    • Mitotic checkpoint genes hBUB1, hBUB1B, hBUB3 and TTK in human bladder cancer, screening for mutations and loss of heterozygosity
    • Olesen S.H., Thykjaer T., Ørntoft T.F. Mitotic checkpoint genes hBUB1, hBUB1B, hBUB3 and TTK in human bladder cancer, screening for mutations and loss of heterozygosity. Carcinogenesis 2001, 22:813-815.
    • (2001) Carcinogenesis , vol.22 , pp. 813-815
    • Olesen, S.H.1    Thykjaer, T.2    Ørntoft, T.F.3
  • 133
    • 0036223590 scopus 로고    scopus 로고
    • Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1
    • Ouyang B., Knauf J.A., Ain K., Nacev B., Fagin J.A. Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1. Clin. Endocrinol. (Oxf.) 2002, 56:341-350.
    • (2002) Clin. Endocrinol. (Oxf.) , vol.56 , pp. 341-350
    • Ouyang, B.1    Knauf, J.A.2    Ain, K.3    Nacev, B.4    Fagin, J.A.5
  • 134
    • 34247608817 scopus 로고    scopus 로고
    • Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells
    • Park H.Y., Jeon Y.K., Shin H.J., Kim I.J., Kang H.C., et al. Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells. Exp. Mol. Med. 2007, 39:195-204.
    • (2007) Exp. Mol. Med. , vol.39 , pp. 195-204
    • Park, H.Y.1    Jeon, Y.K.2    Shin, H.J.3    Kim, I.J.4    Kang, H.C.5
  • 135
    • 49849098630 scopus 로고    scopus 로고
    • Regulation of APC/C activators in mitosis and meiosis
    • Pesin J.A., Orr-Weaver T.L. Regulation of APC/C activators in mitosis and meiosis. Annu. Rev. Cell Dev. Biol. 2008, 24:475-499.
    • (2008) Annu. Rev. Cell Dev. Biol. , vol.24 , pp. 475-499
    • Pesin, J.A.1    Orr-Weaver, T.L.2
  • 136
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: a machine designed to destroy
    • Peters J.-M. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol. 2006, 7:644-656.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 644-656
    • Peters, J.-M.1
  • 137
    • 0037459072 scopus 로고    scopus 로고
    • Un menage a quatre: the molecular biology of chromosome segregation in meiosis
    • Petronczki M., Siomos M.F., Nasmyth K. Un menage a quatre: the molecular biology of chromosome segregation in meiosis. Cell 2003, 112:423-440.
    • (2003) Cell , vol.112 , pp. 423-440
    • Petronczki, M.1    Siomos, M.F.2    Nasmyth, K.3
  • 138
    • 0034654399 scopus 로고    scopus 로고
    • The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1
    • Pfleger C.M., Kirschner M.W. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev. 2000, 14:655-665.
    • (2000) Genes Dev. , vol.14 , pp. 655-665
    • Pfleger, C.M.1    Kirschner, M.W.2
  • 139
    • 24344439888 scopus 로고    scopus 로고
    • The spindle checkpoint: tension versus attachment
    • Pinsky B.A., Biggins S. The spindle checkpoint: tension versus attachment. Trends Cell Biol. 2005, 15:486-493.
    • (2005) Trends Cell Biol. , vol.15 , pp. 486-493
    • Pinsky, B.A.1    Biggins, S.2
  • 140
    • 73349105276 scopus 로고    scopus 로고
    • The kinetochore and the centromere: a working long distance relationship
    • Przewloka M.R., Glover D.M. The kinetochore and the centromere: a working long distance relationship. Annu. Rev. Genet. 2009, 43:439-465.
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 439-465
    • Przewloka, M.R.1    Glover, D.M.2
  • 141
    • 74049151180 scopus 로고    scopus 로고
    • Separating the spindle, checkpoint, and timer functions of BubR1
    • Rahmani Z., Gagou M.E., Lefebvre C., Emre D., Karess R.E. Separating the spindle, checkpoint, and timer functions of BubR1. J. Cell Biol. 2009, 187:597-605.
    • (2009) J. Cell Biol. , vol.187 , pp. 597-605
    • Rahmani, Z.1    Gagou, M.E.2    Lefebvre, C.3    Emre, D.4    Karess, R.E.5
  • 142
    • 15444370589 scopus 로고    scopus 로고
    • Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
    • Rao C.V., Yang Y.M., Swamy M.V., Liu T., Fang Y., et al. Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:4365-4370.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 4365-4370
    • Rao, C.V.1    Yang, Y.M.2    Swamy, M.V.3    Liu, T.4    Fang, Y.5
  • 143
    • 33744984782 scopus 로고    scopus 로고
    • APCcdh1 activity in mouse oocytes prevents entry into the first meiotic division
    • Reis A., Chang H.Y., Levasseur M., Jones K.T. APCcdh1 activity in mouse oocytes prevents entry into the first meiotic division. Nat. Cell Biol. 2006, 8:539-540.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 539-540
    • Reis, A.1    Chang, H.Y.2    Levasseur, M.3    Jones, K.T.4
  • 144
    • 0025098191 scopus 로고
    • Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells
    • Rieder C.L., Alexander S.P. Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells. J. Cell Biol. 1990, 110:81-95.
    • (1990) J. Cell Biol. , vol.110 , pp. 81-95
    • Rieder, C.L.1    Alexander, S.P.2
  • 145
    • 0029160299 scopus 로고
    • The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
    • Rieder C., Cole R., Khodjakov A., Sluder G. The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores. J. Cell Biol. 1995, 130:941-948.
    • (1995) J. Cell Biol. , vol.130 , pp. 941-948
    • Rieder, C.1    Cole, R.2    Khodjakov, A.3    Sluder, G.4
  • 146
    • 44349086295 scopus 로고    scopus 로고
    • Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes
    • Rischitor P.E., May K.M., Hardwick K.G. Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes. PLoS One 2007, 2:e1342.
    • (2007) PLoS One , vol.2
    • Rischitor, P.E.1    May, K.M.2    Hardwick, K.G.3
  • 147
    • 0037097866 scopus 로고    scopus 로고
    • Targeted mutagenesis by homologous recombination in D. melanogaster
    • Rong Y.S., Titen S.W., Xie H.B., Golic M.M., Bastiani M., et al. Targeted mutagenesis by homologous recombination in D. melanogaster. Genes Dev. 2002, 16:1568-1581.
    • (2002) Genes Dev. , vol.16 , pp. 1568-1581
    • Rong, Y.S.1    Titen, S.W.2    Xie, H.B.3    Golic, M.M.4    Bastiani, M.5
  • 148
    • 13944249149 scopus 로고    scopus 로고
    • The Drosophila Grp/Chk1 DNA damage checkpoint controls entry into anaphase
    • Royou A., Macias H., Sullivan W. The Drosophila Grp/Chk1 DNA damage checkpoint controls entry into anaphase. Curr. Biol. 2005, 15:334-339.
    • (2005) Curr. Biol. , vol.15 , pp. 334-339
    • Royou, A.1    Macias, H.2    Sullivan, W.3
  • 149
    • 74549150576 scopus 로고    scopus 로고
    • BubR1- and Polo-coated DNA tethers facilitate poleward segregation of acentric chromatids
    • Royou A., Gagou M.E., Karess R., Sullivan W. BubR1- and Polo-coated DNA tethers facilitate poleward segregation of acentric chromatids. Cell 2010, 140:235-245.
    • (2010) Cell , vol.140 , pp. 235-245
    • Royou, A.1    Gagou, M.E.2    Karess, R.3    Sullivan, W.4
  • 150
    • 79953129453 scopus 로고    scopus 로고
    • Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome
    • Sabino D., Brown N.H., Basto R. Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome. J. Cell Sci. 2011, 124:1156-1166.
    • (2011) J. Cell Sci. , vol.124 , pp. 1156-1166
    • Sabino, D.1    Brown, N.H.2    Basto, R.3
  • 151
    • 0036534146 scopus 로고    scopus 로고
    • Frequent impairment of the spindle assembly checkpoint in hepatocellular carcinoma
    • Saeki A., Tamura S., Ito N., Kiso S., Matsuda Y., et al. Frequent impairment of the spindle assembly checkpoint in hepatocellular carcinoma. Cancer 2002, 94:2047-2054.
    • (2002) Cancer , vol.94 , pp. 2047-2054
    • Saeki, A.1    Tamura, S.2    Ito, N.3    Kiso, S.4    Matsuda, Y.5
  • 152
    • 69849107380 scopus 로고    scopus 로고
    • The life and miracles of kinetochores
    • Santaguida S., Musacchio A. The life and miracles of kinetochores. EMBO J. 2009, 28:2511-2531.
    • (2009) EMBO J. , vol.28 , pp. 2511-2531
    • Santaguida, S.1    Musacchio, A.2
  • 153
    • 79954999102 scopus 로고    scopus 로고
    • Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction
    • Santaguida S., Vernieri C., Villa F., Ciliberto A., Musacchio A. Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. EMBO J. 2011, 30:1508-1519.
    • (2011) EMBO J. , vol.30 , pp. 1508-1519
    • Santaguida, S.1    Vernieri, C.2    Villa, F.3    Ciliberto, A.4    Musacchio, A.5
  • 154
    • 79956266042 scopus 로고    scopus 로고
    • Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis
    • Saurin A.T., van der Waal M.S., Medema R.H., Lens S.M.A., Kops G.J.P.L. Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis. Nat. Commun. 2011, 2:316.
    • (2011) Nat. Commun. , vol.2 , pp. 316
    • Saurin, A.T.1    van der Waal, M.S.2    Medema, R.H.3    Lens, S.M.A.4    Kops, G.J.P.L.5
  • 155
    • 0037178870 scopus 로고    scopus 로고
    • Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated
    • Saxena A., Saffery R., Wong L.H., Kalitsis P., Choo K.H.A. Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated. J. Biol. Chem. 2002, 277:26921-26926.
    • (2002) J. Biol. Chem. , vol.277 , pp. 26921-26926
    • Saxena, A.1    Saffery, R.2    Wong, L.H.3    Kalitsis, P.4    Choo, K.H.A.5
  • 156
    • 69249206590 scopus 로고    scopus 로고
    • Intrakinetochore localization and essential functional domains of Drosophila Spc105
    • Schittenhelm R.B., Chaleckis R., Lehner C.F. Intrakinetochore localization and essential functional domains of Drosophila Spc105. EMBO J. 2009, 28:2374-2386.
    • (2009) EMBO J. , vol.28 , pp. 2374-2386
    • Schittenhelm, R.B.1    Chaleckis, R.2    Lehner, C.F.3
  • 157
    • 53149152614 scopus 로고    scopus 로고
    • The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C)
    • Sczaniecka M., Feoktistova A., May K.M., Chen J.S., Blyth J., et al. The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C). J. Biol. Chem. 2008, 283:23039-23047.
    • (2008) J. Biol. Chem. , vol.283 , pp. 23039-23047
    • Sczaniecka, M.1    Feoktistova, A.2    May, K.M.3    Chen, J.S.4    Blyth, J.5
  • 158
    • 0035844878 scopus 로고    scopus 로고
    • Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity
    • Sharp-Baker H., Chen R.H. Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity. J. Cell Biol. 2001, 153:1239-1250.
    • (2001) J. Cell Biol. , vol.153 , pp. 1239-1250
    • Sharp-Baker, H.1    Chen, R.H.2
  • 159
    • 84861526045 scopus 로고    scopus 로고
    • Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint
    • Shepperd L.A., Meadows J.C., Sochaj A.M., Lancaster T.C., Zou J., et al. Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint. Curr. Biol. 2012, 22:891-899.
    • (2012) Curr. Biol. , vol.22 , pp. 891-899
    • Shepperd, L.A.1    Meadows, J.C.2    Sochaj, A.M.3    Lancaster, T.C.4    Zou, J.5
  • 160
    • 0036141441 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival
    • Shichiri M., Yoshinaga K., Hisatomi H., Sugihara K., Hirata Y. Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival. Cancer Res. 2002, 62:13-17.
    • (2002) Cancer Res. , vol.62 , pp. 13-17
    • Shichiri, M.1    Yoshinaga, K.2    Hisatomi, H.3    Sugihara, K.4    Hirata, Y.5
  • 161
    • 9144242386 scopus 로고    scopus 로고
    • Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability
    • Shin H.J., Baek K.H., Jeon A.H., Park M.T., Lee S.J., et al. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell 2003, 4:483-497.
    • (2003) Cancer Cell , vol.4 , pp. 483-497
    • Shin, H.J.1    Baek, K.H.2    Jeon, A.H.3    Park, M.T.4    Lee, S.J.5
  • 162
    • 0037093326 scopus 로고    scopus 로고
    • Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint
    • Sironi L., Mapelli M., Knapp S., De Antoni A., Jeang K.T., Musacchio A. Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J. 2002, 21:2496-2506.
    • (2002) EMBO J. , vol.21 , pp. 2496-2506
    • Sironi, L.1    Mapelli, M.2    Knapp, S.3    De Antoni, A.4    Jeang, K.T.5    Musacchio, A.6
  • 165
    • 0035802122 scopus 로고    scopus 로고
    • Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
    • Sudakin V., Chan G.K., Yen T.J. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J. Cell Biol. 2001, 154:925-936.
    • (2001) J. Cell Biol. , vol.154 , pp. 925-936
    • Sudakin, V.1    Chan, G.K.2    Yen, T.J.3
  • 166
    • 77953770988 scopus 로고    scopus 로고
    • Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy
    • Suijkerbuijk S.J., van Osch M.H., Bos F.L., Hanks S., Rahman N., Kops G.J. Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy. Cancer Res. 2010, 70:4891-4900.
    • (2010) Cancer Res. , vol.70 , pp. 4891-4900
    • Suijkerbuijk, S.J.1    van Osch, M.H.2    Bos, F.L.3    Hanks, S.4    Rahman, N.5    Kops, G.J.6
  • 168
    • 84867673051 scopus 로고    scopus 로고
    • Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments
    • Suijkerbuijk S.J., Vleugel M., Teixeira A., Kops G.J. Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments. Dev. Cell 2012, 23:745-755.
    • (2012) Dev. Cell , vol.23 , pp. 745-755
    • Suijkerbuijk, S.J.1    Vleugel, M.2    Teixeira, A.3    Kops, G.J.4
  • 169
    • 84864068019 scopus 로고    scopus 로고
    • Rumors of its disassembly have been greatly exaggerated: the secret life of the synaptonemal complex at the centromeres
    • Takeo S., Hawley R.S. Rumors of its disassembly have been greatly exaggerated: the secret life of the synaptonemal complex at the centromeres. PLoS Genet. 2012, 8:e1002807.
    • (2012) PLoS Genet. , vol.8
    • Takeo, S.1    Hawley, R.S.2
  • 170
    • 80755189014 scopus 로고    scopus 로고
    • Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes
    • Takeo S., Lake C.M., Morais-de-Sa E., Sunkel C.E., Hawley R.S. Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes. Curr. Biol. 2011, 21:1845-1851.
    • (2011) Curr. Biol. , vol.21 , pp. 1845-1851
    • Takeo, S.1    Lake, C.M.2    Morais-de-Sa, E.3    Sunkel, C.E.4    Hawley, R.S.5
  • 171
    • 39149109922 scopus 로고    scopus 로고
    • Kinetochore-microtubule interactions: the means to the end
    • Tanaka T.U., Desai A. Kinetochore-microtubule interactions: the means to the end. Curr. Opin. Cell Biol. 2008, 20:53-63.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 53-63
    • Tanaka, T.U.1    Desai, A.2
  • 172
    • 51249102734 scopus 로고    scopus 로고
    • Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy
    • Tanaka K., Mohri Y., Ohi M., Yokoe T., Koike Y., et al. Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy. Clin. Oncol. 2008, 20:639-646.
    • (2008) Clin. Oncol. , vol.20 , pp. 639-646
    • Tanaka, K.1    Mohri, Y.2    Ohi, M.3    Yokoe, T.4    Koike, Y.5
  • 173
    • 0035435063 scopus 로고    scopus 로고
    • Mad2-independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1
    • Tang Z., Bharadwaj R., Li B., Yu H. Mad2-independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. Dev. Cell 2001, 1:227-237.
    • (2001) Dev. Cell , vol.1 , pp. 227-237
    • Tang, Z.1    Bharadwaj, R.2    Li, B.3    Yu, H.4
  • 174
    • 0032514260 scopus 로고    scopus 로고
    • The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
    • Taylor S.S., Ha E., McKeon F. The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase. J. Cell Biol. 1998, 142:1-11.
    • (1998) J. Cell Biol. , vol.142 , pp. 1-11
    • Taylor, S.S.1    Ha, E.2    McKeon, F.3
  • 175
    • 0035694452 scopus 로고    scopus 로고
    • Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells
    • Taylor S.S., Hussein D., Wang Y., Elderkin S., Morrow C.J. Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells. J. Cell Sci. 2001, 114:4385-4395.
    • (2001) J. Cell Sci. , vol.114 , pp. 4385-4395
    • Taylor, S.S.1    Hussein, D.2    Wang, Y.3    Elderkin, S.4    Morrow, C.J.5
  • 178
    • 84870431309 scopus 로고    scopus 로고
    • Cyclin A2 is required for sister chromatid segregation, but not separase control, in mouse oocyte meiosis
    • Touati S.A., Cladiere D., Lister L.M., Leontiou I., Chambon J.P., et al. Cyclin A2 is required for sister chromatid segregation, but not separase control, in mouse oocyte meiosis. Cell Reprod. 2012, 2:1077-1087.
    • (2012) Cell Reprod. , vol.2 , pp. 1077-1087
    • Touati, S.A.1    Cladiere, D.2    Lister, L.M.3    Leontiou, I.4    Chambon, J.P.5
  • 179
    • 11244273059 scopus 로고    scopus 로고
    • The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes
    • Tsurumi C., Hoffmann S., Geley S., Graeser R., Polanski Z. The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes. J. Cell Biol. 2004, 167:1037-1050.
    • (2004) J. Cell Biol. , vol.167 , pp. 1037-1050
    • Tsurumi, C.1    Hoffmann, S.2    Geley, S.3    Graeser, R.4    Polanski, Z.5
  • 180
    • 84875599678 scopus 로고    scopus 로고
    • The KMN protein network-chief conductors of the kinetochore orchestra
    • Varma D., Salmon E.D. The KMN protein network-chief conductors of the kinetochore orchestra. J. Cell Sci. 2012, 125:5927-5936.
    • (2012) J. Cell Sci. , vol.125 , pp. 5927-5936
    • Varma, D.1    Salmon, E.D.2
  • 181
    • 0035854836 scopus 로고    scopus 로고
    • The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing proteins
    • Wang X., Babu J.R., Harden J.M., Jablonski S.A., Gazi M.H., et al. The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing proteins. J. Biol. Chem. 2001, 276:26559-26567.
    • (2001) J. Biol. Chem. , vol.276 , pp. 26559-26567
    • Wang, X.1    Babu, J.R.2    Harden, J.M.3    Jablonski, S.A.4    Gazi, M.H.5
  • 182
    • 10744222603 scopus 로고    scopus 로고
    • BUBR1 deficiency results in abnormal megakaryopoiesis
    • Wang Q., Liu T., Fang Y., Xie S., Huang X., et al. BUBR1 deficiency results in abnormal megakaryopoiesis. Blood 2004, 103:1278-1285.
    • (2004) Blood , vol.103 , pp. 1278-1285
    • Wang, Q.1    Liu, T.2    Fang, Y.3    Xie, S.4    Huang, X.5
  • 183
    • 0141504146 scopus 로고    scopus 로고
    • Metaphase I arrest upon activation of the Mad2-dependent spindle checkpoint in mouse oocytes
    • Wassmann K., Niault T., Maro B. Metaphase I arrest upon activation of the Mad2-dependent spindle checkpoint in mouse oocytes. Curr. Biol. 2003, 13:1596-1608.
    • (2003) Curr. Biol. , vol.13 , pp. 1596-1608
    • Wassmann, K.1    Niault, T.2    Maro, B.3
  • 184
    • 0042978646 scopus 로고    scopus 로고
    • Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
    • Weaver B.A., Bonday Z.Q., Putkey F.R., Kops G.J., Silk A.D., Cleveland D.W. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. J. Cell Biol. 2003, 162:551-563.
    • (2003) J. Cell Biol. , vol.162 , pp. 551-563
    • Weaver, B.A.1    Bonday, Z.Q.2    Putkey, F.R.3    Kops, G.J.4    Silk, A.D.5    Cleveland, D.W.6
  • 185
    • 33846100785 scopus 로고    scopus 로고
    • The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment
    • Wei R.R., Al-Bassam J., Harrison S.C. The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nat. Struct. Mol. Biol. 2007, 14:54-59.
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 54-59
    • Wei, R.R.1    Al-Bassam, J.2    Harrison, S.C.3
  • 186
    • 77953521845 scopus 로고    scopus 로고
    • BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte
    • Wei L., Liang X.W., Zhang Q.H., Li M., Yuan J., et al. BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte. Cell Cycle 2010, 9:1112-1121.
    • (2010) Cell Cycle , vol.9 , pp. 1112-1121
    • Wei, L.1    Liang, X.W.2    Zhang, Q.H.3    Li, M.4    Yuan, J.5
  • 187
    • 77951952612 scopus 로고    scopus 로고
    • Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface
    • Welburn J.P., Vleugel M., Liu D., Yates J.R., Lampson M.A., et al. Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface. Mol. Cell 2010, 38:383-392.
    • (2010) Mol. Cell , vol.38 , pp. 383-392
    • Welburn, J.P.1    Vleugel, M.2    Liu, D.3    Yates, J.R.4    Lampson, M.A.5
  • 188
    • 0035736325 scopus 로고    scopus 로고
    • Kinetochore dynein: its dynamics and role in the transport of the rough deal checkpoint protein
    • Wojcik E., Basto R., Serr M., Scaerou F., Karess R., Hays T. Kinetochore dynein: its dynamics and role in the transport of the rough deal checkpoint protein. Nat. Cell Biol. 2001, 3:1001-1007.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1001-1007
    • Wojcik, E.1    Basto, R.2    Serr, M.3    Scaerou, F.4    Karess, R.5    Hays, T.6
  • 189
    • 36349025888 scopus 로고    scopus 로고
    • Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope
    • Wong O.K., Fang G. Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope. J. Cell Biol. 2007, 179:611-617.
    • (2007) J. Cell Biol. , vol.179 , pp. 611-617
    • Wong, O.K.1    Fang, G.2
  • 190
    • 84863226706 scopus 로고    scopus 로고
    • MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
    • Yamagishi Y., Yang C.H., Tanno Y., Watanabe Y. MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components. Nat. Cell Biol. 2012, 14:746-752.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 746-752
    • Yamagishi, Y.1    Yang, C.H.2    Tanno, Y.3    Watanabe, Y.4
  • 191
    • 33847625012 scopus 로고    scopus 로고
    • Overexpression of BUBR1 is associated with chromosomal instability in bladder cancer
    • Yamamoto Y., Matsuyama H., Chochi Y., Okuda M., Kawauchi S., et al. Overexpression of BUBR1 is associated with chromosomal instability in bladder cancer. Cancer Genet. Cytogenet. 2007, 174:42-47.
    • (2007) Cancer Genet. Cytogenet. , vol.174 , pp. 42-47
    • Yamamoto, Y.1    Matsuyama, H.2    Chochi, Y.3    Okuda, M.4    Kawauchi, S.5
  • 192
    • 41749098779 scopus 로고    scopus 로고
    • Insights into Mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric Mad2 dimer
    • Yang M., Li B., Liu C.-J., Tomchick D.R., Machius M., et al. Insights into Mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric Mad2 dimer. PLoS Biol. 2008, 6:e50.
    • (2008) PLoS Biol. , vol.6
    • Yang, M.1    Li, B.2    Liu, C.-J.3    Tomchick, D.R.4    Machius, M.5
  • 193
    • 84863121505 scopus 로고    scopus 로고
    • BubR1 is modified by sumoylation during mitotic progression
    • Yang F., Hu L., Chen C., Yu J., O'Connell C.B., et al. BubR1 is modified by sumoylation during mitotic progression. J. Biol. Chem. 2012, 287:4875-4882.
    • (2012) J. Biol. Chem. , vol.287 , pp. 4875-4882
    • Yang, F.1    Hu, L.2    Chen, C.3    Yu, J.4    O'Connell, C.B.5
  • 194
    • 84863150248 scopus 로고    scopus 로고
    • Sumoylated BubR1 plays an important role in chromosome segregation and mitotic timing
    • Yang F., Huang Y., Dai W. Sumoylated BubR1 plays an important role in chromosome segregation and mitotic timing. Cell Cycle 2012, 11:797-806.
    • (2012) Cell Cycle , vol.11 , pp. 797-806
    • Yang, F.1    Huang, Y.2    Dai, W.3
  • 195
    • 33749658977 scopus 로고    scopus 로고
    • Bub1 prevents chromosome misalignment and precocious anaphase during mouse oocyte meiosis
    • Yin S., Wang Q., Liu J.H., Ai J.S., Liang C.G., et al. Bub1 prevents chromosome misalignment and precocious anaphase during mouse oocyte meiosis. Cell Cycle 2006, 5:2130-2137.
    • (2006) Cell Cycle , vol.5 , pp. 2130-2137
    • Yin, S.1    Wang, Q.2    Liu, J.H.3    Ai, J.S.4    Liang, C.G.5
  • 196
    • 31544469559 scopus 로고    scopus 로고
    • Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability
    • Yuan B., Xu Y., Woo J.-H., Wang Y., Bae Y.K., et al. Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability. Clin. Cancer Res. 2006, 12:405-410.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 405-410
    • Yuan, B.1    Xu, Y.2    Woo, J.-H.3    Wang, Y.4    Bae, Y.K.5
  • 197
    • 34548304294 scopus 로고    scopus 로고
    • BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment
    • Zhang J., Ahmad S., Mao Y. BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment. J. Cell Biol. 2007, 178:773-784.
    • (2007) J. Cell Biol. , vol.178 , pp. 773-784
    • Zhang, J.1    Ahmad, S.2    Mao, Y.3
  • 198
    • 0037106616 scopus 로고    scopus 로고
    • Attachment and tension in the spindle assembly checkpoint
    • Zhou J., Yao J., Joshi H.C. Attachment and tension in the spindle assembly checkpoint. J. Cell Sci. 2002, 115:3547-3555.
    • (2002) J. Cell Sci. , vol.115 , pp. 3547-3555
    • Zhou, J.1    Yao, J.2    Joshi, H.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.