Rumors of its disassembly have been greatly exaggerated: The secret life of the synaptonemal complex at the centromeres

PLoS Genetics

Volumn 8, Issue 6, 2012, Pages

  Takeo, Satomi ^a,b   Hawley, R Scott ^a,c  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN; PROTEIN SYCP1; PROTEIN SYCP3; UNCLASSIFIED DRUG; CATION TRANSPORT PROTEIN; NUCLEAR PROTEIN; SLC39A3 PROTEIN, MOUSE; SYCP3 PROTEIN, MOUSE;

ARTICLE; CENTROMERE; CHROMOSOME CHIASM; CHROMOSOME PAIRING; CHROMOSOME POSITIONING; CHROMOSOME SEGREGATION; NONHUMAN; PACHYTENE; PROTEIN FUNCTION; SYNAPTONEMAL COMPLEX; TRANSCRIPTION INITIATION SITE; ANIMAL; GENETICS; MALE; MEIOSIS; MOUSE; SPERMATOCYTE;

ANIMALS; CATION TRANSPORT PROTEINS; CENTROMERE; MALE; MEIOSIS; MICE; NUCLEAR PROTEINS; SPERMATOCYTES; SYNAPTONEMAL COMPLEX;

EID: 84864068019     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002807     Document Type: Article

References (14)

1. Takeo S, Lake CM, Morais-de-Sá E, Sunkel CE, Hawley RS, (2011) Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes. Curr Biol 21: 1845-1851.
2. Tsubouchi T, Macqueen AJ, Roeder GS, (2008) Initiation of meiotic chromosome synapsis at centromeres in budding yeast. Genes Dev 22: 3217-3226.
3. Tanneti NS, Landy K, Joyce EF, McKim KS, (2011) A pathway for synapsis initiation during zygotene in Drosophila oocytes. Curr Biol 21: 1852-1857.
4. Martínez-Pérez E, Shaw P, Reader S, Aragón-Alcaide L, Miller T, et al. (1999) Homologous chromosome pairing in wheat. J Cell Sci 112: 1761-1769.
5. Stewart MN, Dawson DS, (2008) Changing partners: moving from non-homologous to homologous centromere pairing in meiosis. Trends Genet 24: 564-573.
6. Holm PB, Rasmussen SW, Zickler D, Lu BC, Sage J, (1981) Chromosome pairing, recombination nodules and chiasma formation in the basidiomycete coprinus cinereus. Carlsberg Research Communications 46: 305-346.
7. Zickler D, Kleckner N, (1999) Meiotic chromosomes: integrating structure and function. Annu Rev Genet 33: 603-754.
8. Gladstone MN, Obeso D, Chuong H, Dawson DS, (2009) The synaptonemal complex protein Zip1 promotes bi-orientation of centromeres at meiosis I. PLoS Genet 5: e1000771 doi:10.1371/journal.pgen.1000771.
9. Newnham L, Jordan P, Rockmill B, Roeder GS, Hoffmann E, (2010) The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I. Proc Natl Acad Sci U S A 107: 781-785.
10. Bisig CG, Guiraldelli MF, Kouznetsova A, Scherthan H, Höög C, et al. (2012) Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. PLoS Genet 8: e1002701 doi:10.1371/journal.pgen.1002701.
11. Qiao H, Chen JK, Reynolds A, Höög C, Paddy M, et al. (2012) Interplay between synaptonemal complex, homologous recombination and centromeres during mammalian meiosis. PLoS Genet 8: e1002790 doi:10.1371/journal.pgen.1002790.
12. Hughes SE, Gilliland WD, Cotitta JL, Takeo S, Collins KA, et al. (2009) Heterochromatic threads connect oscillating chromosomes during prometaphase I in Drosophila oocytes. PLoS Genet 5: e1000348 doi:10.1371/journal.pgen.1000348.
13. Dernburg AF, Sedat JW, Hawley RS, (1996) Direct evidence of a role for heterochromatin in meiotic chromosome segregation. Cell 86: 135-146.
14. de la Fuente R, Parra MT, Viera A, Calvente A, Gomez R, et al. (2007) Meiotic pairing and segregation of achiasmate sex chromosomes in eutherian mammals: the role of SYCP3 protein. PLoS Genet 3: e198 doi:10.1371/journal.pgen.0030198.