메뉴 건너뛰기




Volumn 198, Issue 2, 2012, Pages 205-217

CENP-E-dependent bubr1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; BUB1 RELATED PROTEIN; CENTROMERE PROTEIN E; NDC80 COMPLEX;

EID: 84864980660     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201202152     Document Type: Article
Times cited : (56)

References (54)
  • 1
    • 0034664766 scopus 로고    scopus 로고
    • CENP-E as an essential component of the mitotic checkpoint in vitro
    • Abrieu, A., J.A. Kahana, K.W. Wood, and D.W. Cleveland. 2000. CENP-E as an essential component of the mitotic checkpoint in vitro. Cell. 102:817-826. http://dx.doi.org/10.1016/S0092-8674(00)00070-2
    • (2000) Cell , vol.102 , pp. 817-826
    • Abrieu, A.1    Kahana, J.A.2    Wood, K.W.3    Cleveland, D.W.4
  • 2
    • 79952445057 scopus 로고    scopus 로고
    • BUB1 and BUBR1: multifaceted kinases of the cell cycle
    • Bolanos-Garcia, V.M., and T.L. Blundell. 2011. BUB1 and BUBR1: multifaceted kinases of the cell cycle. Trends Biochem. Sci. 36:141-150. http:// dx.doi.org/10.1016/j.tibs.2010.08.004
    • (2011) Trends Biochem. Sci.. , vol.36 , pp. 141-150
    • Bolanos-Garcia, V.M.1    Blundell, T.L.2
  • 3
    • 0032487444 scopus 로고    scopus 로고
    • Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1
    • Chan, G.K., B.T. Schaar, and T.J. Yen. 1998. Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J. Cell Biol. 143:49-63. http://dx.doi .org/10.1083/jcb.143.1.49
    • (1998) J. Cell Biol. , vol.143 , pp. 49-63
    • Chan, G.K.1    Schaar, B.T.2    Yen, T.J.3
  • 4
    • 0032846338 scopus 로고    scopus 로고
    • Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC
    • Chan, G.K., S.A. Jablonski, V. Sudakin, J.C. Hittle, and T.J. Yen. 1999. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J. Cell Biol. 146:941-954. http://dx.doi.org/10.1083/jcb.146.5.941
    • (1999) J. Cell Biol. , vol.146 , pp. 941-954
    • Chan, G.K.1    Jablonski, S.A.2    Sudakin, V.3    Hittle, J.C.4    Yen, T.J.5
  • 5
    • 33751232957 scopus 로고    scopus 로고
    • The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
    • Cheeseman, I.M., J.S. Chappie, E.M. Wilson-Kubalek, and A. Desai. 2006. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell. 127:983-997. http://dx.doi.org/10.1016/j .cell.2006.09.039
    • (2006) Cell , vol.127 , pp. 983-997
    • Cheeseman, I.M.1    Chappie, J.S.2    Wilson-Kubalek, E.M.3    Desai, A.4
  • 6
    • 0036322225 scopus 로고    scopus 로고
    • BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
    • Chen, R.-H. 2002. BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1. J. Cell Biol. 158:487-496. http://dx.doi.org/10.1083/jcb.200204048
    • (2002) J. Cell Biol. , vol.158 , pp. 487-496
    • Chen, R.-H.1
  • 7
    • 0032547733 scopus 로고    scopus 로고
    • Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores
    • Chen, R.-H., A. Shevchenko, M. Mann, and A.W. Murray. 1998. Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores. J. Cell Biol. 143:283-295. http://dx.doi.org/10.1083/jcb.143.2.283
    • (1998) J. Cell Biol. , vol.143 , pp. 283-295
    • Chen, R.-H.1    Shevchenko, A.2    Mann, M.3    Murray, A.W.4
  • 8
    • 79952523494 scopus 로고    scopus 로고
    • Aurora B regulates formin mDia3 in achieving metaphase chromosome alignment
    • Cheng, L., J. Zhang, S. Ahmad, L. Rozier, H. Yu, H. Deng, and Y. Mao. 2011. Aurora B regulates formin mDia3 in achieving metaphase chromosome alignment. Dev. Cell. 20:342-352. http://dx.doi.org/10.1016/j.devcel .2011.01.008
    • (2011) Dev. Cell. , vol.20 , pp. 342-352
    • Cheng, L.1    Zhang, J.2    Ahmad, S.3    Rozier, L.4    Yu, H.5    Deng, H.6    Mao, Y.7
  • 9
    • 0037459109 scopus 로고    scopus 로고
    • Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling
    • Cleveland, D.W., Y. Mao, and K.F. Sullivan. 2003. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell. 112:407-421. http://dx.doi.org/10.1016/S0092-8674(03)00115-6
    • (2003) Cell , vol.112 , pp. 407-421
    • Cleveland, D.W.1    Mao, Y.2    Sullivan, K.F.3
  • 11
    • 33751227843 scopus 로고    scopus 로고
    • Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
    • DeLuca, J.G., W.E. Gall, C. Ciferri, D. Cimini, A. Musacchio, and E.D. Salmon. 2006. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell. 127:969-982. http://dx.doi.org/10.1016/j.cell .2006.09.047
    • (2006) Cell , vol.127 , pp. 969-982
    • DeLuca, J.G.1    Gall, W.E.2    Ciferri, C.3    Cimini, D.4    Musacchio, A.5    Salmon, E.D.6
  • 12
  • 13
    • 34548436939 scopus 로고    scopus 로고
    • Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions
    • Elowe, S., S. Hümmer, A. Uldschmid, X. Li, and E.A. Nigg. 2007. Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes Dev. 21:2205-2219. http://dx.doi.org/10.1101/gad.436007
    • (2007) Genes Dev , vol.21 , pp. 2205-2219
    • Elowe, S.1    Hümmer, S.2    Uldschmid, A.3    Li, X.4    Nigg, E.A.5
  • 14
    • 72449178000 scopus 로고    scopus 로고
    • Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1
    • Elowe, S., K. Dulla, A. Uldschmid, X. Li, Z. Dou, and E.A. Nigg. 2010. Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J. Cell Sci. 123:84-94. http://dx.doi.org/10.1242/jcs.056507
    • (2010) J. Cell Sci. , vol.123 , pp. 84-94
    • Elowe, S.1    Dulla, K.2    Uldschmid, A.3    Li, X.4    Dou, Z.5    Nigg, E.A.6
  • 15
    • 0036199862 scopus 로고    scopus 로고
    • Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
    • Fang, G. 2002. Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex. Mol. Biol. Cell. 13:755-766. http:// dx.doi.org/10.1091/mbc.01-09-0437
    • (2002) Mol. Biol. Cell. , vol.13 , pp. 755-766
    • Fang, G.1
  • 16
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell, L.H., and M.B. Kastan. 1994. Cell cycle control and cancer. Science. 266:1821-1828. http://dx.doi.org/10.1126/science.7997877
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 18
    • 58149196468 scopus 로고    scopus 로고
    • Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
    • Huang, H., J. Hittle, F. Zappacosta, R.S. Annan, A. Hershko, and T.J. Yen. 2008. Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit. J. Cell Biol. 183:667-680. http://dx.doi .org/10.1083/jcb.200805163
    • (2008) J. Cell Biol. , vol.183 , pp. 667-680
    • Huang, H.1    Hittle, J.2    Zappacosta, F.3    Annan, R.S.4    Hershko, A.5    Yen, T.J.6
  • 19
    • 75749117934 scopus 로고    scopus 로고
    • Mechanisms of force generation by end-on kinetochore-microtubule attachments
    • Joglekar, A.P., K.S. Bloom, and E.D. Salmon. 2010. Mechanisms of force generation by end-on kinetochore-microtubule attachments. Curr. Opin. Cell Biol. 22:57-67. http://dx.doi.org/10.1016/j.ceb.2009.12.010
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 57-67
    • Joglekar, A.P.1    Bloom, K.S.2    Salmon, E.D.3
  • 20
    • 55049093739 scopus 로고    scopus 로고
    • Structure and substrate recruitment of the human spindle checkpoint kinase Bub1
    • Kang, J., M. Yang, B. Li, W. Qi, C. Zhang, K.M. Shokat, D.R. Tomchick, M. Machius, and H. Yu. 2008. Structure and substrate recruitment of the human spindle checkpoint kinase Bub1. Mol. Cell. 32:394-405. http:// dx.doi.org/10.1016/j.molcel.2008.09.017
    • (2008) Mol. Cell. , vol.32 , pp. 394-405
    • Kang, J.1    Yang, M.2    Li, B.3    Qi, W.4    Zhang, C.5    Shokat, K.M.6    Tomchick, D.R.7    Machius, M.8    Yu, H.9
  • 22
    • 43149106486 scopus 로고    scopus 로고
    • CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether
    • Kim, Y., J.E. Heuser, C.M. Waterman, and D.W. Cleveland. 2008. CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. J. Cell Biol. 181:411-419. http:// dx.doi.org/10.1083/jcb.200802189
    • (2008) J. Cell Biol. , vol.181 , pp. 411-419
    • Kim, Y.1    Heuser, J.E.2    Waterman, C.M.3    Cleveland, D.W.4
  • 23
    • 77954740977 scopus 로고    scopus 로고
    • Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E
    • Kim, Y., A.J. Holland, W. Lan, and D.W. Cleveland. 2010. Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell. 142:444-455. http://dx.doi.org/10.1016/j.cell .2010.06.039
    • (2010) Cell , vol.142 , pp. 444-455
    • Kim, Y.1    Holland, A.J.2    Lan, W.3    Cleveland, D.W.4
  • 24
    • 2942567685 scopus 로고    scopus 로고
    • Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
    • Kops, G.J., D.R. Foltz, and D.W. Cleveland. 2004. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc. Natl. Acad. Sci. USA. 101:8699-8704. http://dx.doi .org/10.1073/pnas.0401142101
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , pp. 8699-8704
    • Kops, G.J.1    Foltz, D.R.2    Cleveland, D.W.3
  • 25
    • 58149466576 scopus 로고    scopus 로고
    • Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
    • Kulukian, A., J.S. Han, and D.W. Cleveland. 2009. Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding. Dev. Cell. 16:105-117. http://dx.doi .org/10.1016/j.devcel.2008.11.005
    • (2009) Dev. Cell. 1. , vol.6 , pp. 105-117
    • Kulukian, A.1    Han, J.S.2    Cleveland, D.W.3
  • 26
    • 79952107079 scopus 로고    scopus 로고
    • Sensing centromere tension: Aurora B and the regulation of kinetochore function
    • Lampson, M.A., and I.M. Cheeseman. 2011. Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol. 21:133-140. http://dx.doi.org/10.1016/j.tcb.2010.10.007
    • (2011) Trends Cell Biol , vol.21 , pp. 133-140
    • Lampson, M.A.1    Cheeseman, I.M.2
  • 27
    • 12344266713 scopus 로고    scopus 로고
    • The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments
    • Lampson, M.A., and T.M. Kapoor. 2005. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat. Cell Biol. 7:93-98. http://dx.doi.org/10.1038/ncb1208
    • (2005) Nat. Cell Biol. , vol.7 , pp. 93-98
    • Lampson, M.A.1    Kapoor, T.M.2
  • 28
    • 77949762923 scopus 로고    scopus 로고
    • Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase
    • Liu, D., M. Vleugel, C.B. Backer, T. Hori, T. Fukagawa, I.M. Cheeseman, and M.A. Lampson. 2010. Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase. J. Cell Biol. 188:809-820. http://dx.doi.org/10.1083/jcb.201001006
    • (2010) J. Cell Biol. , vol.188 , pp. 809-820
    • Liu, D.1    Vleugel, M.2    Backer, C.B.3    Hori, T.4    Fukagawa, T.5    Cheeseman, I.M.6    Lampson, M.A.7
  • 29
    • 1842420626 scopus 로고    scopus 로고
    • The Mad2 spindle checkpoint protein has two distinct natively folded states
    • Luo, X., Z. Tang, G. Xia, K. Wassmann, T. Matsumoto, J. Rizo, and H. Yu. 2004. The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat. Struct. Mol. Biol. 11:338-345. http://dx.doi.org/ 10.1038/nsmb748
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 338-345
    • Luo, X.1    Tang, Z.2    Xia, G.3    Wassmann, K.4    Matsumoto, T.5    Rizo, J.6    Yu, H.7
  • 30
    • 58149466578 scopus 로고    scopus 로고
    • BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase
    • Malureanu, L.A., K.B. Jeganathan, M. Hamada, L. Wasilewski, J. Davenport, and J.M. van Deursen. 2009. BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase. Dev. Cell. 16:118-131. http://dx.doi.org/10.1016/j.devcel.2008.11.004
    • (2009) Dev. Cell. , vol.16 , pp. 118-131
    • Malureanu, L.A.1    Jeganathan, K.B.2    Hamada, M.3    Wasilewski, L.4    Davenport, J.5    van Deursen, J.M.6
  • 31
    • 80755135384 scopus 로고    scopus 로고
    • FORMIN a link between kinetochores and microtubule ends
    • Mao, Y. 2011. FORMIN a link between kinetochores and microtubule ends. Trends Cell Biol. 21:625-629. http://dx.doi.org/10.1016/j.tcb.2011.08 .005
    • (2011) Trends Cell Biol. , vol.21 , pp. 625-629
    • Mao, Y.1
  • 32
    • 0038446875 scopus 로고    scopus 로고
    • Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1
    • Mao, Y., A. Abrieu, and D.W. Cleveland. 2003. Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell. 114:87-98. http://dx.doi.org/10.1016/S0092-8674(03) 00475-6
    • (2003) Cell , vol.114 , pp. 87-98
    • Mao, Y.1    Abrieu, A.2    Cleveland, D.W.3
  • 33
    • 24944452696 scopus 로고    scopus 로고
    • Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling
    • Mao, Y., A. Desai, and D.W. Cleveland. 2005. Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. J. Cell Biol. 170:873-880. http://dx.doi.org/10.1083/jcb.200505040
    • (2005) J. Cell Biol. , vol.170 , pp. 873-880
    • Mao, Y.1    Desai, A.2    Cleveland, D.W.3
  • 34
    • 0037183886 scopus 로고    scopus 로고
    • Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2
    • Martin-Lluesma, S., V.M. Stucke, and E.A. Nigg. 2002. Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science. 297:2267-2270. http://dx.doi.org/10.1126/science.1075596
    • (2002) Science , vol.297 , pp. 2267-2270
    • Martin-Lluesma, S.1    Stucke, V.M.2    Nigg, E.A.3
  • 35
    • 34447531017 scopus 로고    scopus 로고
    • Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1
    • Matsumura, S., F. Toyoshima, and E. Nishida. 2007. Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1. J. Biol. Chem. 282:15217-15227. http://dx.doi.org/10.1074/jbc.M611053200
    • (2007) J. Biol. Chem. , vol.282 , pp. 15217-15227
    • Matsumura, S.1    Toyoshima, F.2    Nishida, E.3
  • 36
    • 0035172929 scopus 로고    scopus 로고
    • CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells
    • McEwen, B.F., G.K. Chan, B. Zubrowski, M.S. Savoian, M.T. Sauer, and T.J. Yen. 2001. CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells. Mol. Biol. Cell. 12:2776-2789.
    • (2001) Mol. Biol. Cell. , vol.12
    • McEwen, B.F.1    Chan, G.K.2    Zubrowski, B.3    Savoian, M.S.4    Sauer, M.T.5    Yen, T.J.6
  • 37
    • 0026266161 scopus 로고
    • Cell cycle extracts
    • Murray, A.W. 1991. Cell cycle extracts. Methods Cell Biol. 36:581-605. http:// dx.doi.org/10.1016/S0091-679X(08)60298-8
    • (1991) Methods Cell Biol , vol.36 , pp. 581-605
    • Murray, A.W.1
  • 38
    • 81055155447 scopus 로고    scopus 로고
    • Spindle assembly checkpoint: the third decade
    • Musacchio, A. 2011. Spindle assembly checkpoint: the third decade. Philos. Trans. R. Soc. Lond. B Biol. Sci. 366:3595-3604. http://dx.doi.org/10.1098/ rstb.2011.0072
    • (2011) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.366 , pp. 3595-3604
    • Musacchio, A.1
  • 39
    • 0036744787 scopus 로고    scopus 로고
    • Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENPE
    • Putkey, F.R., T. Cramer, M.K. Morphew, A.D. Silk, R.S. Johnson, J.R. McIntosh, and D.W. Cleveland. 2002. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENPE. Dev. Cell. 3:351-365. http://dx.doi.org/10.1016/S1534-5807(02) 00255-1
    • (2002) Dev. Cell. , vol.3 , pp. 351-365
    • Putkey, F.R.1    Cramer, T.2    Morphew, M.K.3    Silk, A.D.4    Johnson, R.S.5    McIntosh, J.R.6    Cleveland, D.W.7
  • 40
    • 74049151180 scopus 로고    scopus 로고
    • Separating the spindle, checkpoint, and timer functions of BubR1
    • Rahmani, Z., M.E. Gagou, C. Lefebvre, D. Emre, X and R.E. Karess. 2009. Separating the spindle, checkpoint, and timer functions of BubR1. J. Cell Biol. 187:597-605. http://dx.doi.org/10.1083/jcb.200905026
    • (2009) J. Cell Biol. , vol.187 , pp. 597-605
    • Rahmani, Z.1    Gagou, M.E.2    Lefebvre, C.3    Emre, D.4    Karess, R.E.5
  • 41
    • 79958021557 scopus 로고    scopus 로고
    • KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint
    • Rosenberg, J.S., F.R. Cross, and H. Funabiki. 2011. KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint. Curr. Biol. 21:942-947. http://dx.doi.org/10.1016/j.cub.2011.04.011
    • (2011) Curr. Biol. , vol.21 , pp. 942-947
    • Rosenberg, J.S.1    Cross, F.R.2    Funabiki, H.3
  • 42
    • 69849107380 scopus 로고    scopus 로고
    • The life and miracles of kinetochores
    • Santaguida, S., and A. Musacchio. 2009. The life and miracles of kinetochores. EMBO J. 28:2511-2531. http://dx.doi.org/10.1038/emboj.2009.173
    • (2009) EMBO J , vol.28 , pp. 2511-2531
    • Santaguida, S.1    Musacchio, A.2
  • 43
    • 2642549143 scopus 로고    scopus 로고
    • Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing
    • Shah, J.V., E. Botvinick, Z. Bonday, F. Furnari, M. Berns, and D.W. Cleveland. 2004. Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing. Curr. Biol. 14:942-952.
    • (2004) Curr. Biol. , vol.14 , pp. 942-952
    • Shah, J.V.1    Botvinick, E.2    Bonday, Z.3    Furnari, F.4    Berns, M.5    Cleveland, D.W.6
  • 44
    • 0035802122 scopus 로고    scopus 로고
    • Checkpoint inhibition of the APC/ C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
    • Sudakin, V., G.K. Chan, and T.J. Yen. 2001. Checkpoint inhibition of the APC/ C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J. Cell Biol. 154:925-936. http://dx.doi.org/10.1083/jcb.200102093
    • (2001) J. Cell Biol. , vol.154 , pp. 925-936
    • Sudakin, V.1    Chan, G.K.2    Yen, T.J.3
  • 45
    • 77953770988 scopus 로고    scopus 로고
    • Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy
    • Suijkerbuijk, S.J., M.H. van Osch, F.L. Bos, S. Hanks, N. Rahman, and G.J. Kops. 2010. Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy. Cancer Res. 70:4891-4900. http://dx.doi.org/10.1158/0008-5472.CAN-09-4319
    • (2010) Cancer Res , vol.70 , pp. 4891-4900
    • Suijkerbuijk, S.J.1    van Osch, M.H.2    Bos, F.L.3    Hanks, S.4    Rahman, N.5    Kops, G.J.6
  • 47
    • 0042978646 scopus 로고    scopus 로고
    • Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
    • Weaver, B.A., Z.Q. Bonday, F.R. Putkey, G.J. Kops, A.D. Silk, and D.W. Cleveland. 2003. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. J. Cell Biol. 162:551-563. http://dx.doi.org/10.1083/jcb.200303167
    • (2003) J. Cell Biol. , vol.162 , pp. 551-563
    • Weaver, B.A.1    Bonday, Z.Q.2    Putkey, F.R.3    Kops, G.J.4    Silk, A.D.5    Cleveland, D.W.6
  • 48
    • 33846065784 scopus 로고    scopus 로고
    • Aneuploidy acts both oncogenically and as a tumor suppressor
    • Weaver, B.A., A.D. Silk, C. Montagna, P. Verdier-Pinard, and D.W. Cleveland. 2007. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 11:25-36. http://dx.doi.org/10.1016/j.ccr.2006.12.003
    • (2007) Cancer Cell , vol.11 , pp. 25-36
    • Weaver, B.A.1    Silk, A.D.2    Montagna, C.3    Verdier-Pinard, P.4    Cleveland, D.W.5
  • 49
    • 61749084467 scopus 로고    scopus 로고
    • The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility
    • Welburn, J.P., E.L. Grishchuk, C.B. Backer, E.M. Wilson-Kubalek, J.R. Yates III, and I.M. Cheeseman. 2009. The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility. Dev. Cell. 16:374-385. http://dx.doi.org/10.1016/j.devcel.2009.01.011
    • (2009) Dev. Cell. , vol.16 , pp. 374-385
    • Welburn, J.P.1    Grishchuk, E.L.2    Backer, C.B.3    Wilson-Kubalek, E.M.4    Yates III, J.R.5    Cheeseman, I.M.6
  • 50
    • 36349025888 scopus 로고    scopus 로고
    • Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope
    • Wong, O.K., and G. Fang. 2007. Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope. J. Cell Biol. 179:611-617. http://dx.doi.org/10.1083/jcb.200708044
    • (2007) J. Cell Biol. , vol.179 , pp. 611-617
    • Wong, O.K.1    Fang, G.2
  • 51
    • 0001665802 scopus 로고    scopus 로고
    • CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint
    • Yao, X., A. Abrieu, Y. Zheng, K.F. Sullivan, and D.W. Cleveland. 2000. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat. Cell Biol. 2:484-491. http://dx.doi.org/10.1038/35019518
    • (2000) Nat. Cell Biol. , vol.2 , pp. 484-491
    • Yao, X.1    Abrieu, A.2    Zheng, Y.3    Sullivan, K.F.4    Cleveland, D.W.5
  • 53
    • 0026767624 scopus 로고
    • CENP-E is a putative kinetochore motor that accumulates just before mitosis
    • Yen, T.J., G. Li, B.T. Schaar, I. Szilak, and D.W. Cleveland. 1992. CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature. 359:536-539. http://dx.doi.org/10.1038/359536a0
    • (1992) Nature , vol.359 , pp. 536-539
    • Yen, T.J.1    Li, G.2    Schaar, B.T.3    Szilak, I.4    Cleveland, D.W.5
  • 54
    • 34548304294 scopus 로고    scopus 로고
    • BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment
    • Zhang, J., S. Ahmad, and Y. Mao. 2007. BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment. J. Cell Biol. 178:773-784. http://dx.doi.org/10.1083/jcb.200702138
    • (2007) J. Cell Biol. , vol.178 , pp. 773-784
    • Zhang, J.1    Ahmad, S.2    Mao, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.