Timing and checkpoints in the regulation of mitotic progression

Developmental Cell

Volumn 7, Issue 1, 2004, Pages 45-60

  Meraldi, Patrick ^a   Draviam, Viji M ^a   Sorger, Peter K ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; RNA; BUB1 SPINDLE CHECKPOINT PROTEIN; CARRIER PROTEIN; CDCA1 PROTEIN, HUMAN; KNTC2 PROTEIN, HUMAN; MAD1L1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN; PROTEIN KINASE; REPRESSOR PROTEIN;

ACCURACY; ANAPHASE; ARTICLE; CELL CYCLE; CENTROMERE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOSOL; DEPOLYMERIZATION; HELA CELL; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS INHIBITION; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; RNA INTERFERENCE; TIME; GENE; GENETICS; METABOLISM; MICROTUBULE; PHENOTYPE; PHYSIOLOGY;

ANAPHASE; CARRIER PROTEINS; CELL CYCLE PROTEINS; CYTOSOL; GENES, CDC; HELA CELLS; HUMANS; KINETOCHORES; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; NUCLEAR PROTEINS; PHENOTYPE; PHOSPHOPROTEINS; PROTEIN KINASES; REPRESSOR PROTEINS; RNA INTERFERENCE;

EID: 4344610852     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2004.06.006     Document Type: Article

References (52)

1. Canman J.C. Salmon E.D. Fang G. Inducing precocious anaphase in cultured mammalian cells Cell Motil. Cytoskeleton 52 2002 61-65
2. Chen R.H. BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1 J. Cell Biol. 158 2002 487-496
3. Cleveland D.W. Mao Y. Sullivan K.F. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling Cell 112 2003 407-421
4. Clute P. Pines J. Temporal and spatial control of cyclin B1 destruction in metaphase Nat. Cell Biol. 1 1999 82-87
5. DeLuca J.G. Moree B. Hickey J.M. Kilmartin J.V. Salmon E.D. hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells J. Cell Biol. 159 2002 549-555
6. Dobles M. Liberal V. Scott M.L. Benezra R. Sorger P.K. Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 Cell 101 2000 635-645
7. Elbashir S.M. Harborth J. Lendeckel W. Yalcin A. Weber K. Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 428-429
8. Fang G. Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex Mol. Biol. Cell 13 2002 755-766
9. Gardner R.D. Poddar A. Yellman C. Tavormina P.A. Monteagudo M.C. Burke D.J. The spindle checkpoint of the yeast Saccharomyces cerevisiae requires kinetochore function and maps to the CBF3 domain Genetics 157 2001 1493-1502
10. Gergely F. Draviam V.M. Raff J.W. The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells Genes Dev. 17 2002 336-341
11. Gillett E.S. Espelin C.W. Sorger P.K. Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast J. Cell Biol. 164 2004 535-546
12. Gorbsky G.J. The mitotic spindle checkpoint Curr. Biol. 11 2001 R1001-R1004
13. Gorbsky G.J. Chen R.H. Murray A.W. Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase J. Cell Biol. 141 1998 1193-1205
14. Guardavaccaro D. Kudo Y. Boulaire J. Barchi M. Busino L. Donzelli M. Margottin-Goguet F. Jackson P.K. Yamasaki L. Pagano M. Control of meiotic and mitotic progression by the F box protein β-Trcp1 in vivo Dev. Cell 4 2003 799-812
15. Habu T. Kim S.H. Weinstein J. Matsumoto T. Identification of a MAD2-binding protein, CMT2, and its role in mitosis EMBO J. 21 2002 6419-6428
16. Harborth J. Elbashir S. Bechert K. Tuschl T. Weber K. Identification of essential genes in cultured mammalian cells using small interfering RNAs J. Cell Sci. 114 2001 4557-4565
17. He X. Rines D.R. Espelin C.W. Sorger P.K. Molecular analysis of kinetochore-microtubule attachment in budding yeast Cell 106 2001 195-206
18. Hori T. Haraguchi T. Hiraoka Y. Kimura H. Fukagawa T. Dynamic behavior of Nuf2-HEC1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells J. Cell Sci. 116 2003 3347-3362
19. Hoffman D.B. Pearson C.G. Yen T.J. Howell B.J. Salmon E.D. Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores Mol. Biol. Cell 12 2001 1995-2009
20. Howell B.J. Hoffman D.B. Fang G. Murray A.W. Salmon E.D. Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells J. Cell Biol. 150 2000 1233-1250
21. Hoyt M.A. A new view of the spindle checkpoint J. Cell Biol. 154 2001 909-911
22. Hoyt M.A. Totis L. Roberts B.T. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function Cell 66 1991 507-517
23. Jablonski S.A. Chan G.K. Cooke C.A. Earnshaw W.C. Yen T.J. The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis Chromosoma 107 1998 386-396
24. Kalitsis P. Earle E. Fowler K.J. Choo K.H. Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis Genes Dev. 14 2000 2277-2282
25. Kanda T. Sullivan K.F. Wahl G.M. Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells Curr. Biol. 8 1998 377-385
26. Li R. Murray A.W. Feedback control of mitosis in budding yeast Cell 66 1991 519-531
27. Li X. Nicklas R.B. Mitotic forces control a cell-cycle checkpoint Nature 373 1995 630-632
28. Liu S.T. Hittle J.C. Jablonski S.A. Campbell M.S. Yoda K. Yen T.J. Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis Nat. Cell Biol. 5 2003 341-345
29. Margottin-Goguet F. Hsu J.Y. Loktev A. Hsieh H.M. Reimann J.D. Jackson P.K. Prophase destruction of Emi1 by the SCF(βTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase Dev. Cell 4 2003 813-826
30. Martinez-Exposito M.J. Kaplan K.B. Copeland J. Sorger P.K. Retention of the BUB3 checkpoint protein on lagging chromosomes Proc. Natl. Acad. Sci. USA 96 1999 8493-8498
31. Martin-Lluesma S. Stucke V.M. Nigg E.A. Role of HEC1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2 Science 297 2002 2267-2270
32. McCleland M.L. Gardner R.D. Kallio M.J. Daum J.R. Gorbsky G.J. Burke D.J. Stukenberg P.T. The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity Genes Dev. 17 2003 101-114
33. Michel L.S. Liberal V. Chatterjee A. Kirchwegger R. Pasche B. Gerald W. Dobles M. Sorger P.K. Murty V.V. Benezra R. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells Nature 409 2001 355-359
34. Millband D.N. Hardwick K.G. Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner Mol. Cell Biol. 22 2002 2728-2742
35. Murray A.W. Kirschner M.W. Dominoes and clocks: the union of two views of the cell cycle Science 246 1989 614-621
36. Musacchio A. Hardwick K.G. The spindle checkpoint: structural insights into dynamic signalling Nat. Rev. Mol. Cell Biol. 3 2002 731-741
37. Mythily D.V. Krishna S. Tergaonkar V. Pleiotropic effects of human papillomavirus type 16 E6 oncogene expression in human epithelial cell lines J. Gen. Virol. 80 1999 1707-1713
38. Nabetani A. Koujin T. Tsutsumi C. Haraguchi T. Hiraoka Y. A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: a link between the kinetochore function and the spindle checkpoint Chromosoma 110 2001 322-334
39. Nasmyth K. Segregating sister genomes: the molecular biology of chromosome separation Science 297 2002 559-565
40. Peters J.M. The anaphase-promoting complex: proteolysis in mitosis and beyond Mol. Cell 9 2002 931-943
41. Pines J. Localization of cell cycle regulators by immunofluorescence Methods Enzymol. 283 1997 99-113
42. Reimann J.D. Freed E. Hsu Y.J. Kramer R.E. Peters J. Jackson P.K. Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex Cell 105 2001 645-655
43. Reimann J.D. Gardner B.E. Margottin-Goguet F. Jackson P.K. Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins Genes Dev. 15 2001 3278-3285
44. Rieder C.L. Schultz A. Cole R. Sluder G. Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle J. Cell Biol. 127 1994 1301-1310
45. Rieder C.L. Cole R.W. Khodjakov A. Sluder G. The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores J. Cell Biol. 130 1995 941-948
46. Shannon K.B. Canman J.C. Salmon E.D. Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension Mol. Biol. Cell 13 2002 3706-3719
47. Shelby R.D. Hahn K.M. Sullivan K.F. Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells J. Cell Biol. 135 1996 545-557
48. Sironi L. Melixetian M. Faretta M. Prosperini E. Helin K. Musacchio A. Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint EMBO J. 20 2001 6371-6382
49. Sudakin V. Chan G.K. Yen T.J. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 J. Cell Biol. 154 2001 925-936
50. Tang Z. Bharadwaj R. Li B. Yu H. Mad2-independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1 Dev. Cell 1 2001 227-237
51. Taylor S.S. McKeon F. Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage Cell 89 1997 727-735
52. Tournebize R. Popov A. Kinoshita K. Ashford A.J. Rybina S. Pozniakovsky A. Mayer T.U. Walczak C.E. Karsenti E. Hyman A.A. Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts Nat. Cell Biol. 2 2000 13-19