Crystal structure of the tetrameric Mad1-Mad2 core complex: Implications of a 'safety belt' binding mechanism for the spindle checkpoint

EMBO Journal

Volumn 21, Issue 10, 2002, Pages 2496-2506

  Sironi, Lucia ^a   Mapelli, Marina ^a   Knapp, Stefan ^a   De Antoni, Anna ^b   Jeang, Kuan Teh ^c   Musacchio, Andrea ^d  

^a DIVISION OF REPRODUCTIVE BIOLOGY   (United States)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c RESEARCH AND DEVELOPMENT   (Australia)

^d EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

Anaphase; Cdc20; Mad1; Mad2; Mitotic spindle checkpoint

Indexed keywords

CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 20; PROTEIN MAD1; PROTEIN MAD2; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CENTROMERE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENERGY; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN CONFORMATION; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0037093326     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.10.2496     Document Type: Article

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