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Volumn 20, Issue 7, 2013, Pages 852-868

New molecular and cellular targets for chemoprevention and treatment of skin tumors by plant polyphenols: A critical review

Author keywords

AhR; Cellular senescence; EGFR; Epigenetics; Melanoma; Plant polyphenols; Skin cancers; Stem cells

Indexed keywords

ACTEOSIDE; ANTHOCYANIN; ANTINEOPLASTIC AGENT; CAPSAICIN; CATECHIN; CURCUMIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GENISTEIN; HYPERICIN; ISOFLAVONE; LEONTOPODIC ACID; PLANT GLYCOSIDE; POLYDANTIN; POLYPHENOL; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; SILIBININ; SILYMARIN; STILBENE DERIVATIVE; TEUPOLIOSIDE; TRICHOSTATIN A; UNCLASSIFIED DRUG;

EID: 84877995487     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867311320070002     Document Type: Review
Times cited : (28)

References (243)
  • 1
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal, B.B.; Shishodia, S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem. Pharmacol., 2006 , 71(10), 1397-1421.
    • (2006) Biochem. Pharmacol. , vol.71 , Issue.10 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 2
    • 34547689211 scopus 로고    scopus 로고
    • UV-induced immune suppression and photocarcinogenesis: Chemoprevention by dietary botanical agents
    • DOI 10.1016/j.canlet.2007.02.010, PII S0304383507000687
    • Katiyar, S.K. UV-induced immune suppression and photocarcinogenesis: chemoprevention by dietary botanical agents. Cancer Lett., 2007, 255(1), 1-11. (Pubitemid 47212603)
    • (2007) Cancer Letters , vol.255 , Issue.1 , pp. 1-11
    • Katiyar, S.K.1
  • 3
    • 82955181009 scopus 로고    scopus 로고
    • Polyphenols Skin photoprotection and inhibition of photocarcinogenesis
    • Afaq, F.; Katiyar, S.K. Polyphenols: skin photoprotection and inhibition of photocarcinogenesis. Mini Rev. Med. Chem., 2011, 11(14), 1200-1215.
    • (2011) Mini Rev. Med. Chem. , vol.11 , Issue.14 , pp. 1200-1215
    • Afaq, F.1    Katiyar, S.K.2
  • 4
    • 21744443080 scopus 로고    scopus 로고
    • Chemoprevention of skin cancer by grape constituent resveratrol: Relevance to human disease?
    • DOI 10.1096/fj.04-3582fje
    • Aziz, M.H.; Reagan-Shaw, S.; Wu, J.; Longley B.J.; Ahmad, N. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? FASEB J., 2005, 19(9), 1193-1195. (Pubitemid 40946462)
    • (2005) FASEB Journal , vol.19 , Issue.9 , pp. 1193-1195
    • Aziz, M.H.1    Reagan-Shaw, S.2    Wu, J.3    Longley, B.J.4    Ahmad, N.5
  • 5
    • 70450182123 scopus 로고    scopus 로고
    • Plant polyphenols and tumors: From mechanims to therapy, prevention, and protection against toxicity of anti-cancer treatments
    • Korkina, L.G.; De Luca, C.; Kostyuk, V.A.; Pastore, S. Plant polyphenols and tumors: from mechanims to therapy, prevention, and protection against toxicity of anti-cancer treatments. Curr. Med. Chem., 2009, 16(30), 3943-3965.
    • (2009) Curr. Med. Chem. , vol.16 , Issue.30 , pp. 3943-3965
    • Korkina, L.G.1    De Luca, C.2    Kostyuk, V.A.3    Pastore, S.4
  • 6
    • 70350599525 scopus 로고    scopus 로고
    • High-fat diet exacerbates inflammation and cell survival signals in the skin of ultraviolet birradiated c57bl/6 mice
    • Meeran, S. M.; Singh, T.; Nagy, T. R.; Katiyar, S. K., High-fat diet exacerbates inflammation and cell survival signals in the skin of ultraviolet Birradiated C57BL/6 mice. Toxicol Appl Pharmacol 2009, 241(3), 303-310.
    • (2009) Toxicol Appl Pharmacol , vol.241 , Issue.3 , pp. 303-310
    • Meeran, S.M.1    Singh, T.2    Nagy, T.R.3    Katiyar, S.K.4
  • 7
    • 77953499756 scopus 로고    scopus 로고
    • Epigenetic remedies by dietary phytochemicals against inflammatory skin disorders: Myth or reality?
    • Vanden Berghe, W.; Haegeman, G. Epigenetic remedies by dietary phytochemicals against inflammatory skin disorders: myth or reality? Curr. Drug Metab., 2010, 11(5), 436-450.
    • (2010) Curr. Drug Metab. , vol.11 , Issue.5 , pp. 436-450
    • Vanden Berghe, W.1    Haegeman, G.2
  • 10
    • 23144462546 scopus 로고    scopus 로고
    • Cancer and ageing: A nexus at several levels
    • DOI 10.1038/nrc1675
    • Balducci, L.; Ershler, W.B. Cancer and ageing: a nexus at several levels. Nat. Rev. Cancer, 2005, 5(8), 655-662. (Pubitemid 41081391)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.8 , pp. 655-662
    • Balducci, L.1    Ershler, W.B.2
  • 11
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh, Y. J., Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer, 2003, 3(10), 768-780.
    • (2003) Nat. Rev. Cancer , vol.3 , Issue.10 , pp. 768-780
    • Surh, Y.J.1
  • 13
    • 36749081135 scopus 로고    scopus 로고
    • Resveratrol as an antioxidant and pro-oxidant agent: Mechanisms and clinical implications
    • DOI 10.1042/BST0351156
    • De la Lastra, C.A.; Villegas, I. Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications. Biochem. Soc. Trans., 2007, 35(Pt5), 1156-1160. (Pubitemid 350206449)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1156-1160
    • Alarcon De La Lastra, C.1    Villegas, I.2
  • 14
    • 58149357364 scopus 로고    scopus 로고
    • Metabolism of plant polyphenols in the skin: Beneficial versus deleterious effects
    • Korkina, L.; Pastore, S.; De Luca, C.; Kostyuk, V. Metabolism of plant polyphenols in the skin: beneficial versus deleterious effects. Curr. Drug Metab., 2008, 9(8), 710-729.
    • (2008) Curr. Drug Metab. , vol.9 , Issue.8 , pp. 710-729
    • Korkina, L.1    Pastore, S.2    De Luca, C.3    Kostyuk, V.4
  • 15
    • 39449111547 scopus 로고    scopus 로고
    • Anticarcinogenesis by dietary phytochemicals: Cytoprotection by nrf2 in normal cells and cytotoxicity by modulation of transcription factors nf-kb and ap-1 in abnormal cancer cells
    • Gopalacrishnan, A.; Kong, A.N.T. Anticarcinogenesis by dietary phytochemicals: cytoprotection by Nrf2 in normal cells and cytotoxicity by modulation of transcription factors NF-kB and AP-1 in abnormal cancer cells. Food Chem. Toxicol., 2008, 46(4), 1257-1270.
    • (2008) Food Chem. Toxicol. , vol.46 , Issue.4 , pp. 1257-1270
    • Gopalacrishnan, A.1    Kong, A.N.T.2
  • 16
    • 77958130983 scopus 로고    scopus 로고
    • Cancer chemoprevention mechanisms mediated through the keap1-nrf2 pathway
    • Hayes, J.D.; McMahon, M.; Chowdhry, S.; Dinkova-Kostova, A. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway. Antioxid. Redox Signal., 2010, 13(11), 1713-1748.
    • (2010) Antioxid. Redox Signal. , vol.13 , Issue.11 , pp. 1713-1748
    • Hayes, J.D.1    McMahon, M.2    Chowdhry, S.3    Dinkova-Kostova, A.4
  • 18
    • 74049120454 scopus 로고    scopus 로고
    • Nrf2: Friend or foe for chemoprevention?
    • Kensler, T.W.; Wakabayashi, N. Nrf2: friend or foe for chemoprevention? Carcinogenesis, 2010, 31(1), 90-99.
    • (2010) Carcinogenesis , vol.31 , Issue.1 , pp. 90-99
    • Kensler, T.W.1    Wakabayashi, N.2
  • 19
    • 77649271223 scopus 로고    scopus 로고
    • The rise of antioxidant signaling -The evolution and hormetic actions of nrf2
    • Maher, J.; Yamamoto, M. The rise of antioxidant signaling -The evolution and hormetic actions of Nrf2. Toxicol. Appl. Pharmacol., 2010, 244(1), 4-15.
    • (2010) Toxicol. Appl. Pharmacol. , vol.244 , Issue.1 , pp. 4-15
    • Maher, J.1    Yamamoto, M.2
  • 22
    • 84866676019 scopus 로고    scopus 로고
    • (Iso) flav(an)ones, chalcones, catechins, and theaflavins as anticarcinogens: Mechanisms, anti-multidrug resistance and QSAR studies
    • Mercader, A.G.; Pomilio, A.B. (Iso)flav(an)ones, chalcones, catechins, and theaflavins as anticarcinogens: mechanisms, anti-multidrug resistance and QSAR studies. Curr. Med. Chem., 2012, 19(25), 4324-4347.
    • (2012) Curr. Med. Chem. , vol.19 , Issue.25 , pp. 4324-4347
    • Mercader, A.G.1    Pomilio, A.B.2
  • 23
    • 33644837942 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs for cancer prevention: Promise, perils and pharmacogenetics
    • DOI 10.1038/nrc1801, PII N1801
    • Ulrich, C.M., Bigler, J., Potter, J.D. Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics. Nat. Rev. Cancer, 2006, 6(2), 130-140. (Pubitemid 43361545)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.2 , pp. 130-140
    • Ulrich, C.M.1    Bigler, J.2    Potter, J.D.3
  • 24
    • 83555177230 scopus 로고    scopus 로고
    • Inflamm-Aging of the stem cell niche: Breast cancer as a paradigmatic example: Breakdown of the multi-shell cytokine network fuels cancer in aged people
    • Bonafé, M.; Storci, G.; Franceschi, C. Inflamm-Aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people. Bioessays, 2011, 34(1), 40-49.
    • (2011) Bioessays , vol.34 , Issue.1 , pp. 40-49
    • Bonafé, M.1    Storci, G.2    Franceschi, C.3
  • 25
    • 79955003370 scopus 로고    scopus 로고
    • The tissue-specific stem cell as a target for chemoprevention
    • Maund, S.L.; Cramer, S.D. The Tissue-Specific Stem Cell as a Target for Chemoprevention Stem Cell Rev., 2011, 7(2), 307-314.
    • (2011) Stem Cell Rev. , vol.7 , Issue.2 , pp. 307-314
    • Maund, S.L.1    Cramer, S.D.2
  • 26
    • 0038819885 scopus 로고    scopus 로고
    • Stem-cell hierarchy in skin cancer
    • DOI 10.1038/nrc1095
    • Perez-Losada, J.; Balmain, A. Stem-cell hierarchy in skin cancer. Nat. Rev. Cancer, 2003, 3(6), 434-443. (Pubitemid 37328847)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 434-443
    • Perez-Losada, J.1    Balmain, A.2
  • 27
    • 68149164966 scopus 로고    scopus 로고
    • The canonical nf-kappab pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population
    • Pratt, M.A.; Tibbo, E.; Robertson, S.J.; Jansson, D.; Hurst, K.; Perez-Iratxeta, C.; Lau, R.; Niu, M.Y. The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population. Oncogene, 2009, 28(30), 2710-2722.
    • (2009) Oncogene , vol.28 , Issue.30 , pp. 2710-2722
    • Pratt, M.A.1    Tibbo, E.2    Robertson, S.J.3    Jansson, D.4    Hurst, K.5    Perez-Iratxeta, C.6    Lau, R.7    Niu, M.Y.8
  • 29
    • 79952121979 scopus 로고    scopus 로고
    • Inducible formation of breast cancer stem cells and their dynamic equilibrium with nonstem cancer cells via il6 secretion
    • Iliopoulos, D.; Hirsch, H.A.; Wang, G.; Struhl, K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with nonstem cancer cells via IL6 secretion. Proc. Natl. Acad. Sci. USA, 2011, 108(4),1397-1402.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , Issue.4 , pp. 1397-1402
    • Iliopoulos, D.1    Hirsch, H.A.2    Wang, G.3    Struhl, K.4
  • 30
    • 77949881221 scopus 로고    scopus 로고
    • The senescence associated secretory phenotype: The dark side of tumor suppression
    • Coppé, J.P.; Desprez, P.Y.; Krtolica, A.; Campisi, J. The senescence associated secretory phenotype: the dark side of tumor suppression. Ann. Rev. Pathol., 2010, 5(2), 99-118.
    • (2010) Ann. Rev. Pathol. , vol.5 , Issue.2 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 31
    • 79953793768 scopus 로고    scopus 로고
    • Radiation induced nontargeted response: Mechanism and potential clinical implications
    • Hei, T.K.; Zhou, H.; Chai, Y.; Ponnaiya, B.; Ivanov, V.N. Radiation induced nontargeted response: mechanism and potential clinical implications. Curr. Mol. Pharmacol., 2011, 4(2), 96-105.
    • (2011) Curr. Mol. Pharmacol. , vol.4 , Issue.2 , pp. 96-105
    • Hei, T.K.1    Zhou, H.2    Chai, Y.3    Ponnaiya, B.4    Ivanov, V.N.5
  • 33
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier, F; Campisi, J. Four faces of cellular senescence. J. Cell Biol., 2011,192(4), 547-556.
    • (2011) J. Cell Biol. , vol.192 , Issue.4 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 34
    • 80053030114 scopus 로고    scopus 로고
    • The cancer stem cell niche-There goes the neighborhood?
    • Cabarcas, S.M.; Mathews, L.A.; Farrar W.L. The cancer stem cell niche-There goes the neighborhood? Int. J. Cancer, 2011, 129(10), 2315-2327.
    • (2011) Int. J. Cancer , vol.129 , Issue.10 , pp. 2315-2327
    • Cabarcas, S.M.1    Mathews, L.A.2    Farrar, W.L.3
  • 35
    • 44649101304 scopus 로고    scopus 로고
    • Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
    • DOI 10.1016/j.cell.2008.03.039, PII S009286740800620X
    • Kuilman, T.; Michaloglou, C.; Vredeveld, L.C.; Douma, S.; van Doorn, R.; Desmet, C.J.; Aarden, L.A.; Mooi, W.J.; Peeper, D.S. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell, 2008, 133(6), 1019-1031. (Pubitemid 351787746)
    • (2008) Cell , vol.133 , Issue.6 , pp. 1019-1031
    • Kuilman, T.1    Michaloglou, C.2    Vredeveld, L.C.W.3    Douma, S.4    Van Doorn, R.5    Desmet, C.J.6    Aarden, L.A.7    Mooi, W.J.8    Peeper, D.S.9
  • 36
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • DOI 10.1016/S0140-6736(00)04046-0
    • Balkwill, F.; Mantovani, A. Inflammation and cancer: back to Virchow? Lancet, 2001, 357(9255), 539-545. (Pubitemid 32173595)
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 37
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • DOI 10.1038/nature01322
    • Coussens, L.M.; Werb, Z. Inflammation and cancer. Nature, 2002, 420(6917), 860-867. (Pubitemid 36019639)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 38
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
    • Biswas SK; Mantovani, A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol., 2010, 11(10), 889-896.
    • (2010) Nat. Immunol. , vol.11 , Issue.10 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 39
    • 80053531658 scopus 로고    scopus 로고
    • Regulation of cancer stem cells by cytokine networks: Attacking cancer's inflammatory roots
    • Korkaya, H.; Liu, S.; Wicha, M.S. Regulation of cancer stem cells by cytokine networks: Attacking cancer's inflammatory roots. Clin. Cancer Res., 2011, 17(19), 6125-6129.
    • (2011) Clin. Cancer Res. , vol.17 , Issue.19 , pp. 6125-6129
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 40
    • 80052358980 scopus 로고    scopus 로고
    • Therapeutic strategies for the clinical blockade of il-6/gp130 signaling
    • Jones, S.A.; Scheller, J.; Rose-John, S. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J. Clin. Invest., 2011, 121(9), 3375-3383.
    • (2011) J. Clin. Invest. , vol.121 , Issue.9 , pp. 3375-3383
    • Jones, S.A.1    Scheller, J.2    Rose-John, S.3
  • 41
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: A balancing act of stem cells in the skin
    • Blanpain, C.; Fuchs, E., Epidermal homeostasis: a balancing act of stem cells in the skin. Nat. Rev. Mol. Cell. Biol., 2009, 10(3), 207-217.
    • (2009) Nat. Rev. Mol. Cell. Biol. , vol.10 , Issue.3 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 43
    • 34250666186 scopus 로고    scopus 로고
    • Oxidative stress of neural, hematopoietic, and stem cells: Protection by natural compounds
    • DOI 10.1089/rej.2006.0515
    • Shytle, R. D.; Ehrhart, J.; Tan, J.; Vila, J.; Cole, M.; Sanberg, C. D.; Sanberg, P. R.; Bickford, P. C., Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds. Rejuvenation Res., 2007, 10(2), 173-178. (Pubitemid 46944985)
    • (2007) Rejuvenation Research , vol.10 , Issue.2 , pp. 173-178
    • Shytle, R.D.1    Ehrhart, J.2    Tan, J.3    Vila, J.4    Cole, M.5    Sanberg, C.D.6    Sanberg, P.R.7    Bickford, P.C.8
  • 44
    • 53549083542 scopus 로고    scopus 로고
    • Targeting cancer stem cells with phytochemicals
    • Kawasaki, B. T.; Hurt, E. M.; Mistree, T.; Farrar, W. L., Targeting cancer stem cells with phytochemicals. Mol. Interv., 2008, 8(4), 174-184.
    • (2008) Mol. Interv. , vol.8 , Issue.4 , pp. 174-184
    • Kawasaki, B.T.1    Hurt, E.M.2    Mistree, T.3    Farrar, W.L.4
  • 46
  • 47
    • 33744961079 scopus 로고    scopus 로고
    • Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells: Requirement of the transcriptional repressor HBP1
    • DOI 10.1074/jbc.M513378200
    • Kim, J.; Zhang, X.; Rieger-Christ, K.; Summerhayes, I.C.; Wazer, D.E.; Paulson, K.E.; Yee, A.S. Suppression of Wnt signaling by the green tea compound ()-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1. J. Biol. Chem., 2006, 281(16), 10865-10875. (Pubitemid 43855509)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.16 , pp. 10865-10875
    • Kim, J.1    Zhang, X.2    Rieger-Christ, K.M.3    Summerhayes, I.C.4    Wazer, D.E.5    Paulson, K.E.6    Yee, A.S.7
  • 48
    • 77951063726 scopus 로고    scopus 로고
    • Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer
    • Slusarz , A.; Shenouda, N.; Sakla, M. Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer. Cancer Res., 2010, 70(8), 3382-3390.
    • (2010) Cancer Res. , vol.70 , Issue.8 , pp. 3382-3390
    • Slusarz, A.1    Shenouda, N.2    Sakla, M.3
  • 49
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick, L.; Moorhead, P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res., 1961, 25(3), 585-621.
    • (1961) Exp. Cell Res. , vol.25 , Issue.3 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 52
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • DOI 10.1016/S0092-8674(01)00492-5
    • Blackburn, E.H. Switching and signaling at the telomere. Cell, 2001, 106 (6), 661-673. (Pubitemid 32900658)
    • (2001) Cell , vol.106 , Issue.6 , pp. 661-673
    • Blackburn, E.H.1
  • 53
    • 0034630432 scopus 로고    scopus 로고
    • Accumulation of short telomeres in human fibroblasts prior to replicative senescence
    • DOI 10.1006/excr.2000.4823
    • Martens, U.M.; Chavez, E. A.; Poon, S.S.S.; Schmoor, C.; Lansdorp, P.M. Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exper. Cell Res., 2000, 256(1), 291-299. (Pubitemid 30211191)
    • (2000) Experimental Cell Research , vol.256 , Issue.1 , pp. 291-299
    • Martens, U.M.1    Chavez, E.A.2    Poon, S.S.S.3    Schmoor, C.4    Lansdorp, P.M.5
  • 55
    • 0032487675 scopus 로고    scopus 로고
    • Both Rb/p16(INK4a) inactivation and telomerase activity are required to immortalize human epithelial cells
    • DOI 10.1038/23962
    • Kiyono, T.; Foster, S.A.; Koop, J.I.; McDougall, J.K.; Galloway, D.A.; Klingelhutz, A.J. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature, 1998, 396(6706), 84-88. (Pubitemid 28520454)
    • (1998) Nature , vol.396 , Issue.6706 , pp. 84-88
    • Kiyono, T.1    Foster, S.A.2    Koop, J.I.3    McDougall, J.K.4    Galloway, D.A.5    Klingelhutz, A.J.6
  • 57
    • 20444370974 scopus 로고    scopus 로고
    • What has senescence got to do with cancer?
    • DOI 10.1016/j.ccr.2005.05.025, PII S1535610805001662
    • Dimri, G.P. What has senescence got to do with cancer? Cancer Cell, 2005, 7(6), 505-512. (Pubitemid 40799244)
    • (2005) Cancer Cell , vol.7 , Issue.6 , pp. 505-512
    • Dimri, G.P.1
  • 58
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hahn, D.; Weinberg, R.A. The hallmarks of cancer. Cell, 2000, 100(1), 57-70. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 59
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
    • DOI 10.1016/S0092-8674(00)81902-9
    • Serrano, M.; Lin, A.W.; McCurrach, M.E.; Beach, D.; Lowe, S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 1997, 88(5), 593-602. (Pubitemid 27152402)
    • (1997) Cell , vol.88 , Issue.5 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 60
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay, J.W.; Bacchetti, S. A survey of telomerase activity in human cancer. Eur. J. Cancer Part A, 1997, 33(5), 787-791.
    • (1997) Eur. J. Cancer Part A , vol.33 , Issue.5 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 61
    • 27744527486 scopus 로고    scopus 로고
    • The first molecular details of alt in human tumor cells
    • Muntoni, A.; Reddel, R.R. The first molecular details of ALT in human tumor cells. Human Mol. Gen., 2005, 14(2), 191-196.
    • (2005) Human Mol. Gen. , vol.14 , Issue.2 , pp. 191-196
    • Muntoni, A.1    Reddel, R.R.2
  • 62
    • 34247581288 scopus 로고    scopus 로고
    • Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence
    • DOI 10.1016/j.ccr.2007.02.026, PII S1535610807000876
    • Feldser, D.M;. Greider, C.W. Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell, 2007, 11(5), 461-469. (Pubitemid 46670077)
    • (2007) Cancer Cell , vol.11 , Issue.5 , pp. 461-469
    • Feldser, D.M.1    Greider, C.W.2
  • 63
    • 34247860915 scopus 로고    scopus 로고
    • Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
    • DOI 10.1038/sj.embor.7400937, PII 7400937
    • Cosme-Blanco, W.; Shen, M. F.; Lazar, A. J. F.; Pathak, S.; Lozano, G.; Multani, A.S.; Chang S. Telomere dysfunction suppresses spontaneous tu morigenesis in vivo by initiating p53-dependent cellular senescence. EMBO Rep., 2007, 8(5), 497-503. (Pubitemid 46696521)
    • (2007) EMBO Reports , vol.8 , Issue.5 , pp. 497-503
    • Cosme-Blanco, W.1    Shen, M.-F.2    Lazar, A.J.F.3    Pathak, S.4    Lozano, G.5    Multani, A.S.6    Chang, S.7
  • 64
    • 0037013154 scopus 로고    scopus 로고
    • INK4a contributes to the outcome of cancer therapy
    • DOI 10.1016/S0092-8674(02)00734-1
    • Schmitt, C.A.; Fridman, J.S., Yang, M.; Lee, S.; Baranov, E.; Hoffman, R.M.; Lowe, S.W. A senescence program controlled by p53 and p16 contributes to the outcome of cancer therapy. Cell, 2002, 109(3), 335-346. (Pubitemid 34606876)
    • (2002) Cell , vol.109 , Issue.3 , pp. 335-346
    • Schmitt, C.A.1    Fridman, J.S.2    Yang, M.3    Lee, S.4    Baranov, E.5    Hoffman, R.M.6    Lowe, S.W.7
  • 66
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • DOI 10.1038/nature05529, PII NATURE05529
    • Xue, W.; Zender, L.; Miething, C.; Dickins, R.A.; Hernando, E.; Krizhanovsky, V.; Cordon-Cardo, C.; Lowe, S.W. Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas. Nature, 2007, 445(7128), 656-660. (Pubitemid 46232886)
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6    Cordon-Cardo, C.7    Lowe, S.W.8
  • 67
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier, F.; Campisi, J. Four faces of cellular senescence. J. Cell Biol., 2011, 192(4), 547-556.
    • (2011) J. Cell Biol. , vol.192 , Issue.4 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 69
    • 0036815596 scopus 로고    scopus 로고
    • Tumor senescence as a determinant of drug response in vivo
    • DOI 10.1016/S1368764602001103, PII S1368764602001103
    • Roninson, I.B. Tumor senescence as a determinant of drug response in vivo. Drug Resist. Updates, 2002, 5(5), 204-208. (Pubitemid 35429450)
    • (2002) Drug Resistance Updates , vol.5 , Issue.5 , pp. 204-208
    • Roninson, I.B.1
  • 72
    • 31344477255 scopus 로고    scopus 로고
    • The evolution of late life
    • DOI 10.1016/j.arr.2005.06.003, PII S156816370500019X
    • Rauser, C.L.; Mueller, L.D.; Rose, M.R. The evolution of late life. Ageing Res. Rev., 2006, 5(1), 14-32. (Pubitemid 43139665)
    • (2006) Ageing Research Reviews , vol.5 , Issue.1 , pp. 14-32
    • Rauser, C.L.1    Mueller, L.D.2    Rose, M.R.3
  • 74
    • 1842861744 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock
    • DOI 10.1016/j.yexcr.2004.01.017, PII S001448270400031X
    • Munro, J.; Barr, N.; Ireland, H.; Morrison, V.; Parkinson, E. Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock. Exper. Cell Res., 2004, 259(2), 525-538. (Pubitemid 38490504)
    • (2004) Experimental Cell Research , vol.295 , Issue.2 , pp. 525-538
    • Munro, J.1    Barr, N.I.2    Ireland, H.3    Morrison, V.4    Parkinson, E.K.5
  • 75
    • 78651505157 scopus 로고    scopus 로고
    • Therapeutic potential of activators and inhibitors of sirtuins
    • Balcerczyk, A.; Pirola L. Therapeutic potential of activators and inhibitors of sirtuins. Biofactors, 2010, 36(5), 383-393.
    • (2010) Biofactors , vol.36 , Issue.5 , pp. 383-393
    • Balcerczyk, A.1    Pirola, L.2
  • 76
    • 77955608578 scopus 로고    scopus 로고
    • Sirtuin family: A link to metabolic signaling and senescence
    • Kyrylenko, S.; Baniahmad, A. Sirtuin family: a link to metabolic signaling and senescence. Curr. Med. Chem., 2010, 17(26), 2921-2932.
    • (2010) Curr. Med. Chem. , vol.17 , Issue.26 , pp. 2921-2932
    • Kyrylenko, S.1    Baniahmad, A.2
  • 77
    • 2942532642 scopus 로고    scopus 로고
    • Trichostatin A - Like hydroxamate histone deacetylase inhibitors as therapeutic agents: Toxicological point of view
    • Vanhaecke, T.; Papeleu, P.; Elaut, G.; Rogiers, V. Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view. Curr. Med. Chem., 2004, 11(2), 1629-1643. (Pubitemid 38735799)
    • (2004) Current Medicinal Chemistry , vol.11 , Issue.12 , pp. 1629-1643
    • Vanhaecke, T.1    Papeleu, P.2    Elaut, G.3    Rogiers, V.4
  • 79
    • 78049510453 scopus 로고    scopus 로고
    • Taming the beast within: Resveratrol suppresses colitis and prevents colon cancer
    • Hofseth, L.J.; Singh, U.P.; Singh, N.P.; Nagarkatti, M.; Nagarkatti, P.S. Taming the beast within: resveratrol suppresses colitis and prevents colon cancer. Aging (Albany NY), 2010, 2(4), 183-184.
    • (2010) Aging (Albany NY) , vol.2 , Issue.4 , pp. 183-184
    • Hofseth, L.J.1    Singh, U.P.2    Singh, N.P.3    Nagarkatti, M.4    Nagarkatti, P.S.5
  • 80
    • 84869001241 scopus 로고    scopus 로고
    • Anti-inflammatory effects of concentrated ethanol extracts of edelweiss (leontopodium alpinum cass.) callus cultures towards human keratinocytes and endothelial cells
    • article ID 498393 doi: 10.1155/2012/498373
    • Lulli, D.; Potapovich, A.; Maurelli, R.; Dellambra, E.; Pressi, G.; Kostyuk, V.; Dal Toso, R.; De Luca, C.; Pastore, S.; Korkina, L. Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells. Mediators Inflamm., 2012, article ID 498393, doi: 10.1155/2012/498373.
    • (2012) Mediators Inflamm.
    • Lulli, D.1    Potapovich, A.2    Maurelli, R.3    Dellambra, E.4    Pressi, G.5    Kostyuk, V.6    Dal Toso, R.7    De Luca, C.8    Pastore, S.9    Korkina, L.10
  • 83
    • 46749122327 scopus 로고    scopus 로고
    • Beyond wavy hairs: The epidermal growth factor receptor and its ligands in skin biology and pathology
    • DOI 10.2353/ajpath.2008.070942
    • Schneider, M.R.; Werner, S.; Paus, R.; Wolf, E. Beyond wavy hairs. The epidermal growth factor receptor and its ligands in skin biology and pathology. Am. J. Pathol., 2008, 173(1), 14-24. (Pubitemid 351947951)
    • (2008) American Journal of Pathology , vol.173 , Issue.1 , pp. 14-24
    • Schneider, M.R.1    Werner, S.2    Paus, R.3    Wolf, E.4
  • 84
    • 43749094998 scopus 로고    scopus 로고
    • The epidermal growth factor receptor system in skin repair and inflammation
    • DOI 10.1038/sj.jid.5701184, PII 5701184
    • Pastore, S.; Mascia, F.; Mariani, V.; Girolomoni, G. The epidermal growth factor receptor system in skin repair and inflammation. J. Invest. Dermatol., 2008, 128(6), 1365-1374. (Pubitemid 351693180)
    • (2008) Journal of Investigative Dermatology , vol.128 , Issue.6 , pp. 1365-1374
    • Pastore, S.1    Mascia, F.2    Mariani, V.3    Girolomoni, G.4
  • 85
    • 0043172403 scopus 로고    scopus 로고
    • Transactivation joins multiple tracks to the ERK/MAPK cascade
    • DOI 10.1038/nrm1173
    • Wetzker, R.; Böhmer, F.D. Transactivation joins multiple tracks to the ERK/MAPK cascade. Nat. Rev. Mol. Cell. Biol., 2003, 4(8), 651-657. (Pubitemid 36934967)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.8 , pp. 651-657
    • Wetzker, R.1    Bohmer, F.-D.2
  • 86
    • 30044445761 scopus 로고    scopus 로고
    • RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling
    • DOI 10.1074/jbc.M508650200
    • Canguilhem, B.; Pradines, A.; Baudouin, C.; Boby, C.; Lajoie-Mazenc, I.; Charveron, M.; Favre, G. RhoB protects human keratinocytes from UVBinduced apoptosis through epidermal growth factor receptor signaling. J. Biol. Chem., 2005, 280(52), 43257-43263. (Pubitemid 43049292)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.52 , pp. 43257-43263
    • Canguilhem, B.1    Pradines, A.2    Baudouin, C.3    Boby, C.4    Lajoie-Mazenc, I.5    Charveron, M.6    Favre, G.7
  • 87
    • 67349083594 scopus 로고    scopus 로고
    • Skin toxicities associated with epidermal growth factor receptor inhibitors
    • Li, T.; Perez-Soler, R. Skin toxicities associated with epidermal growth factor receptor inhibitors. Target Oncol., 2009, 4(2), 107-119.
    • (2009) Target Oncol. , vol.4 , Issue.2 , pp. 107-119
    • Li, T.1    Perez-Soler, R.2
  • 88
    • 0027767476 scopus 로고
    • Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas
    • Dominey, A.M.; Wang, H.J.; King, L.; Nanney, L.B.; Gagne, T.A.; Sellheyer, K.; Bundman, D.S.; Longley, M.A.; Rothnagel, J.A.; Greenhalgh, D.A. Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ., 1993, 4(12), 1071-1082.
    • (1993) Cell Growth Differ. , vol.4 , Issue.12 , pp. 1071-1082
    • Dominey, A.M.1    Wang, H.J.2    King, L.3    Nanney, L.B.4    Gagne, T.A.5    Sellheyer, K.6    Bundman, D.S.7    Longley, M.A.8    Rothnagel, J.A.9    Greenhalgh, D.A.10
  • 89
    • 0026668643 scopus 로고
    • Transgenic overexpression of tgf-bypasses the need for c-ha-ras mutations in mouse skin tumorigenesis
    • Vassar, R.; Hutton, M.E.; Fuch, E. Transgenic overexpression of TGF-bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis. Mol. Cell. Biol., 1992, 12(10), 4643-4653.
    • (1992) Mol. Cell. Biol. , vol.12 , Issue.10 , pp. 4643-4653
    • Vassar, R.1    Hutton, M.E.2    Fuch, E.3
  • 90
    • 0030755457 scopus 로고    scopus 로고
    • Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras
    • Dlugosz, A.A.; Hansen, L.; Cheng, C.; Alexander, N.; Denning, M.F.; Threadgill, D.W.; Magnuson, T.; Coffey, R.J.; Yuspa, S.H. Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) ondogene but does not block in vitro keratinocyte responses to oncogenic ras. Cancer Res., 1997, 57(15), 3180-3188. (Pubitemid 27351733)
    • (1997) Cancer Research , vol.57 , Issue.15 , pp. 3180-3188
    • Diugosz, A.A.1    Hansen, L.2    Cheng, C.3    Alexander, N.4    Denning, M.F.5    Threadgill, D.W.6    Magnuson, T.7    Coffey Jr., R.J.8    Yuspa, S.H.9
  • 91
    • 0034235628 scopus 로고    scopus 로고
    • The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
    • Hansen, L.A.; Woodson, R.L.; Holbus, S.; Strain, K.; Lo, Y.C.; Yuspa, S.H. The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors. Cancer Res., 2000, 60(13), 3328-3332. (Pubitemid 30482140)
    • (2000) Cancer Research , vol.60 , Issue.13 , pp. 3328-3332
    • Hansen, L.A.1    Woodson II, R.L.2    Holbus, S.3    Strain, K.4    Lo, Y.-C.5    Yuspa, S.H.6
  • 93
    • 18144371160 scopus 로고    scopus 로고
    • Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor
    • DOI 10.1158/0008-5472.CAN-04-2204
    • El-Abaseri, T.B.; Fuhrman, J.; Trempus, C.; Shendrik, I.; Tennant, T.W.; Hansen, L.A. Chemoprevention of UV-light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor. Cancer Res., 2005, 65(9), 3958-3965. (Pubitemid 40616379)
    • (2005) Cancer Research , vol.65 , Issue.9 , pp. 3958-3965
    • El-Abaseri, T.B.1    Fuhrman, J.2    Trempus, C.3    Shendrik, I.4    Tennant, R.W.5    Hansen, L.A.6
  • 94
    • 33746485766 scopus 로고    scopus 로고
    • Epidermal Growth Factor Receptor Targeting in Cancer
    • DOI 10.1053/j.seminoncol.2006.04.003, PII S0093775406001771
    • Mendelsohn, J.; Baselga, J. Epidermal growth factor receptor targeting in cancer. Semin. Oncol., 2006, 33(4), 369-385. (Pubitemid 44142736)
    • (2006) Seminars in Oncology , vol.33 , Issue.4 , pp. 369-385
    • Mendelsohn, J.1    Baselga, J.2
  • 97
    • 33646154001 scopus 로고    scopus 로고
    • Detection of egfr-And her2-Activating mutations in squamous cell carcinoma involving the head and neck
    • Willmore-Payne, C.; Holden, J.A.; Layfield, L.J. Detection of EGFR-And HER2-Activating mutations in squamous cell carcinoma involving the head and neck. Mol. Pathol., 2006, 19(9), 634-640.
    • (2006) Mol. Pathol. , vol.19 , Issue.9 , pp. 634-640
    • Willmore-Payne, C.1    Holden, J.A.2    Layfield, L.J.3
  • 98
    • 33845532991 scopus 로고    scopus 로고
    • Characterization of the expression and activation of the epidermal growth factor receptor in squamous cell carcinoma of the skin
    • DOI 10.1111/j.1365-2133.2006.07603.x
    • Fogarty, G.B.; Conus, N.M.; Chu, J.; McArthur, G. Characterization of the expression and activation of the epidermal growth factor receptor in squamous cell carcinoma of the skin. Br. J. Dermatol., 2007, 156(1), 92-98. (Pubitemid 44924151)
    • (2007) British Journal of Dermatology , vol.156 , Issue.1 , pp. 92-98
    • Fogarty, G.B.1    Conus, N.M.2    Chu, J.3    McArthur, G.4
  • 99
    • 0034980383 scopus 로고    scopus 로고
    • Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin
    • DOI 10.1159/000051637
    • Shimizu, T.; Izumi, H.; Oga, A.; Furumoto, H.; Murakami, T.; Ofuji, R.; Muto, M.; Sasaki, K. Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous cell of the skin. Dermatology, 2001, 202(3), 203-206. (Pubitemid 32506966)
    • (2001) Dermatology , vol.202 , Issue.3 , pp. 203-206
    • Shimizu, T.1    Izumi, H.2    Oga, A.3    Furumoto, H.4    Murakami, T.5    Ofuji, R.6    Muto, M.7    Sasaki, K.8
  • 100
    • 22144456041 scopus 로고    scopus 로고
    • The promise of molecular targeted therapies: Protein kinase inhibitors in the treatment of cutaneous malignancies
    • DOI 10.1016/j.jaad.2005.02.011, PII S019096220500678X
    • Kondapalli, L.; Soltani, K.; Lacouture, M.E. The promise of moleculartargeted therapies: protein kinase inhibitors in the treatment of cutaneous malignancies. J. Am. Acad. Dermatol., 2005, 53(2), 291-302. (Pubitemid 40979587)
    • (2005) Journal of the American Academy of Dermatology , vol.53 , Issue.2 , pp. 291-302
    • Kondapalli, L.1    Soltani, K.2    Lacouture, M.E.3
  • 102
    • 0031283517 scopus 로고    scopus 로고
    • Crosstalk between elevation of intracellular [ca2+], reactive oxygen species and phospholipase a2 stimulation in a human keratinocyte cell line
    • Goldman, R.; Moshonov, S.; Chen, X.; Berchansky, A.; Furstenberger, G.; Zor, U. Crosstalk between elevation of intracellular [Ca2+], reactive oxygen species and phospholipase A2 stimulation in a human keratinocyte cell line Adv. Exp. Med. Biol., 1997, 433(1), 41-45.
    • (1997) Adv. Exp. Med. Biol. , vol.433 , Issue.1 , pp. 41-45
    • Goldman, R.1    Moshonov, S.2    Chen, X.3    Berchansky, A.4    Furstenberger, G.5    Zor, U.6
  • 103
    • 30044436233 scopus 로고    scopus 로고
    • Receptor-type protein-tyrosine phosphatase-κ regulates epidermal growth factor receptor function
    • DOI 10.1074/jbc.M507722200
    • Xu, Y.; Grachtchouk, V.; Voorhees, J.J.; Fisher, G.J. Receptor-Type proteintyrosine phosphatase-regulates epidermal growth factor receptor function. J. Biol. Chem., 2005, 280(52), 42694-42700. (Pubitemid 43049228)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.52 , pp. 42694-42700
    • Xu, Y.1    Tan, L.-J.2    Grachtchouk, V.3    Voorhees, J.J.4    Fisher, G.J.5
  • 104
    • 29144531357 scopus 로고    scopus 로고
    • Functional studies of protein tyrosine phosphatases with chemical approaches
    • Zhang, Z.Y. Functional studies of protein tyrosine phosphatases with chemical approaches. Biochim. Biophys. Acta, 2005, 1754(1-2), 100-107.
    • (2005) Biochim. Biophys. Acta , vol.1754 , Issue.1-2 , pp. 100-107
    • Zhang, Z.Y.1
  • 105
    • 55249083541 scopus 로고    scopus 로고
    • Oxidative inactivation of protein tyrosine phosphatise 1b by organic hydroperoxides
    • Bhattacharya, S.; LaButti, J.N.; Seiner, D.R.; Gates, K.S. Oxidative inactivation of protein tyrosine phosphatise 1B by organic hydroperoxides. Bioorg. Med. Chem. Lett., 2008, 18(22), 5856-5859.
    • (2008) Bioorg. Med. Chem. Lett. , vol.18 , Issue.22 , pp. 5856-5859
    • Bhattacharya, S.1    LaButti, J.N.2    Seiner, D.R.3    Gates, K.S.4
  • 106
    • 33748743056 scopus 로고    scopus 로고
    • Oxidative inhibition of receptor-type protein-tyrosine phosphatase κ by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes
    • DOI 10.1074/jbc.M602355200
    • Xu, Y.; Shao, Y.; Voorhees, J.J.; Fisher, G.J. Oxidative inhibition of receptor-Type proteine-Tyrosine phosphatase by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J. Biol. Chem., 2006, 281(37), 27389-27397. (Pubitemid 44401766)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.37 , pp. 27389-27397
    • Xu, Y.1    Shao, Y.2    Voorhees, J.J.3    Fisher, G.J.4
  • 107
    • 31544471428 scopus 로고    scopus 로고
    • Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
    • DOI 10.1093/carcin/bgi220
    • El-Abaseri, T.B.; Putta, S.; Hansen, L.A. Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor. Carcinogenesis, 2006, 27(2), 225-231. (Pubitemid 43159873)
    • (2006) Carcinogenesis , vol.27 , Issue.2 , pp. 225-231
    • El-Abaseri, T.B.1    Putta, S.2    Hansen, L.A.3
  • 108
    • 0038306878 scopus 로고    scopus 로고
    • Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation
    • Mascia, F.; Mariani, V.; Girolomoni, G.; Pastore, S. Blockade of EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation. Am. J. Pathol., 2003, 163(1), 303-312. (Pubitemid 36759615)
    • (2003) American Journal of Pathology , vol.163 , Issue.1 , pp. 303-312
    • Mascia, F.1    Mariani, V.2    Girolomoni, G.3    Pastore, S.4
  • 109
    • 0038189571 scopus 로고    scopus 로고
    • Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors
    • Sørensen, O.E.; Cowland, J.B.; Theilgaard-Mönch, K.; Liu, L.; Ganz, T.; Borregaard, N. Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J. Immunol., 2003, 170(11), 5583-5589. (Pubitemid 36617848)
    • (2003) Journal of Immunology , vol.170 , Issue.11 , pp. 5583-5589
    • Sorensen, O.E.1    Cowland, J.B.2    Theilgaard-Monch, K.3    Liu, L.4    Ganz, T.5    Borregaard, N.6
  • 111
  • 115
    • 33749018219 scopus 로고    scopus 로고
    • Mechanisms of cutaneous toxicities to EGFR inhibitors
    • DOI 10.1038/nrc1970, PII NRC1970
    • Lacouture, M.E. Mechanisms of cutaneous toxicities to EGFR inhibitors. Nat. Rev. Cancer., 2006; 6(10), 803-812. (Pubitemid 44450468)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.10 , pp. 803-812
    • Lacouture, M.E.1
  • 116
    • 50249085093 scopus 로고    scopus 로고
    • Flavonoids as rtk inhibitors and potential anticancer agents
    • Teillet, F.; Boumendjel, A.; Boutonnat, J.; Ronot, X. Flavonoids as RTK inhibitors and potential anticancer agents. Med. Res. Rev., 2008, 28(5), 715-745.
    • (2008) Med. Res. Rev. , vol.28 , Issue.5 , pp. 715-745
    • Teillet, F.1    Boumendjel, A.2    Boutonnat, J.3    Ronot, X.4
  • 117
    • 84858951714 scopus 로고    scopus 로고
    • Curcumin: Updated molecular mechanisms and intervention targets in human lung cancer
    • Ye, M.X.; Li, Y.; Yin, H.; Zhang, J. Curcumin: updated molecular mechanisms and intervention targets in human lung cancer. Int. J. Mol. Sci., 2012, 13(3), 3959-3978.
    • (2012) Int. J. Mol. Sci. , vol.13 , Issue.3 , pp. 3959-3978
    • Ye, M.X.1    Li, Y.2    Yin, H.3    Zhang, J.4
  • 118
    • 70349970838 scopus 로고    scopus 로고
    • Curcumin inhibits the migration and invasion of human a549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and 9 and vascular endothelial growth factor (vegf)
    • Lin, S.S.; Laai, K.C.; Hsu, S.C.; Yang, J.S.; Kuo, C.L.; Lin, J.P.; Ma, Y.S.; Wu, C.C.; Chung, J.G. Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and 9 and Vascular Endothelial Growth Factor (VEGF) Cancer Lett., 2009, 285(1), 127-133.
    • (2009) Cancer Lett. , vol.285 , Issue.1 , pp. 127-133
    • Lin, S.S.1    Laai, K.C.2    Hsu, S.C.3    Yang, J.S.4    Kuo, C.L.5    Lin, J.P.6    Ma, Y.S.7    Wu, C.C.8    Chung, J.G.9
  • 119
    • 79953301141 scopus 로고    scopus 로고
    • Suppression of egf-induced tumor cell migration and matrix metalloproteinase-9 expression by capsaicin via the inhibition of egfr-mediated fak/akt, pkc/raf/erk, p38 mapk, and ap-1 signaling
    • Hwang, Y.P.; Yun, H.J.; Choi, J.H.; Han, E.H.; Kim, H.G.; Song, G.Y.; Kwon, K.I.; Jeong, T,C.; Jeong, H.G. Suppression of EGF-induced tumor cell migration and matrix metalloproteinase-9 expression by capsaicin via the inhibition of EGFR-mediated FAK/Akt, PKC/Raf/ERK, p38 MAPK, and AP-1 signaling. Mol. Nutr. Food Res., 2011, 55(4), 594-605.
    • (2011) Mol. Nutr. Food Res. , vol.55 , Issue.4 , pp. 594-605
    • Hwang, Y.P.1    Yun, H.J.2    Choi, J.H.3    Han, E.H.4    Kim, H.G.5    Song, G.Y.6    Kwon, K.I.7    Jeong, T.C.8    Jeong, H.G.9
  • 120
    • 84858643750 scopus 로고    scopus 로고
    • Inflammasomes in carcinogenesis and anticancer immune responses
    • Zitvogel, L.; Kepp, O.; Galluzzi, L.; Kroemer, G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat. Immunol., 2012, 13(4), 343-351.
    • (2012) Nat. Immunol. , vol.13 , Issue.4 , pp. 343-351
    • Zitvogel, L.1    Kepp, O.2    Galluzzi, L.3    Kroemer, G.4
  • 121
    • 84865430034 scopus 로고    scopus 로고
    • Polymeric black tea polyphenols modulate the localization and activity of 12-o-Tetradecanoyl phorbol-13-Acetate-mediated kinases in mouse skin: Mechanisms of their anti-Tumor-promoting action
    • Kumar, G.; Dange, P.; Kailaje, V.; Vaidya, M.M.; Ramchandani, A.G.; Maru, G.B. Polymeric black tea polyphenols modulate the localization and activity of 12-O-Tetradecanoyl phorbol-13-Acetate-mediated kinases in mouse skin: Mechanisms of their anti-Tumor-promoting action. Free Radic. Biol. Med., 2012, 53(6), 1358-1370.
    • (2012) Free Radic. Biol. Med. , vol.53 , Issue.6 , pp. 1358-1370
    • Kumar, G.1    Dange, P.2    Kailaje, V.3    Vaidya, M.M.4    Ramchandani, A.G.5    Maru, G.B.6
  • 122
    • 79960981915 scopus 로고    scopus 로고
    • Plant phenylpropanoids as emerging anti-inflammatory agents
    • Korkina, L.; Kostyuk, V.; De Luca, C.; Pastore, S. Plant phenylpropanoids as emerging anti-inflammatory agents. Mini Rev. Med. Chem., 2011, 11(10), 823-835.
    • (2011) Mini Rev. Med. Chem. , vol.11 , Issue.10 , pp. 823-835
    • Korkina, L.1    Kostyuk, V.2    De Luca, C.3    Pastore, S.4
  • 123
    • 77951703599 scopus 로고    scopus 로고
    • Pathobiology of chronic inflammatory skin diseases: Interplay between keratinocytes and immune cells as a target for antiinflammatory drugs
    • Albanesi, C.; Pastore, S. Pathobiology of chronic inflammatory skin diseases: interplay between keratinocytes and immune cells as a target for antiinflammatory drugs. Curr. Drug Metab., 2010, 11(3), 210-227.
    • (2010) Curr. Drug Metab. , vol.11 , Issue.3 , pp. 210-227
    • Albanesi, C.1    Pastore, S.2
  • 124
    • 34447280138 scopus 로고    scopus 로고
    • Molecular mechanisms underlying wound healing and anti-inflammatory properties of naturally occurring biotechnologically produced phenylpropanoid glycosides
    • DOI 10.1170/T822
    • Korkina, L.G.; Mikhal'chik, E.; Suprun, M.V.; Pastore, S.; Dal Toso, R. Molecular mechanisms underlying wound healing and anti-inflammatory properties of naturally occurring biotechnologically produced phenylpropanoid glycosides. Cell. Mol. Biol. (Noisy-le-grand), 2007, 53(5), 84-91. (Pubitemid 350164309)
    • (2007) Cellular and Molecular Biology , vol.53 , Issue.5 , pp. 84-91
    • Korkina, L.G.1    Mikhal'chik, E.V.2    Suprun, M.V.3    Pastore, S.4    Dal Toso, R.5
  • 125
    • 80051600588 scopus 로고    scopus 로고
    • Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors nfb and ahr and egfr-erk pathway
    • Potapovich, A.I.; Lulli, D.; Fidanza, P.; Kostyuk, V.A.; De Luca, C.; Pastore, S.; Korkina, L.G. Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFB and AhR and EGFR-ERK pathway. Toxicol. Appl. Pharmacol., 2011, 255(2), 138-149.
    • (2011) Toxicol. Appl. Pharmacol. , vol.255 , Issue.2 , pp. 138-149
    • Potapovich, A.I.1    Lulli, D.2    Fidanza, P.3    Kostyuk, V.A.4    De Luca, C.5    Pastore, S.6    Korkina, L.G.7
  • 126
    • 84855408119 scopus 로고    scopus 로고
    • Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system
    • Pastore, S.; Lulli, D.; Fidanza, P.; Potapovich, A.I.; Kostyuk, V.A.; De Luca, C.; Mikhal'chik, E.; Korkina, L.G.. 2012. Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system. Antioxid. Redox Signal., 2012, 16(4), 314-328.
    • (2012) Antioxid. Redox Signal. 2012 , vol.16 , Issue.4 , pp. 314-328
    • Pastore, S.1    Lulli, D.2    Fidanza, P.3    Potapovich, A.I.4    Kostyuk, V.A.5    De Luca, C.6    Mikhal'chik, E.7    Korkina, L.G.8
  • 127
    • 79959840030 scopus 로고    scopus 로고
    • Differential modulation of stress-inflammation responses by plant polyphenols in cultured normal human keratinocytes and immortalized hacat cells
    • Pastore, S.; Lulli, D.; Potapovich, A.I.; Fidanza, P.; Kostyuk, V.A.; Dellambra, E.; De Luca, C.; Maurelli, R.; Korkina, L.G. Differential modulation of stress-inflammation responses by plant polyphenols in cultured normal human keratinocytes and immortalized HaCaT cells. J. Dermatol. Sci., 2011, 63(2), 104-114.
    • (2011) J. Dermatol. Sci. , vol.63 , Issue.2 , pp. 104-114
    • Pastore, S.1    Lulli, D.2    Potapovich, A.I.3    Fidanza, P.4    Kostyuk, V.A.5    Dellambra, E.6    De Luca, C.7    Maurelli, R.8    Korkina, L.G.9
  • 128
    • 33745342580 scopus 로고    scopus 로고
    • NFκB pathway: A good signaling paradigm and therapeutic target
    • DOI 10.1016/j.biocel.2006.03.023, PII S1357272506001245
    • Tergaonkar, V. NF-kappaB pathway: a good signaling paradigm and therapeutic target. Int. J. Biochem. Cell Biol., 2006, 38(10), 1647-1653. (Pubitemid 43947652)
    • (2006) International Journal of Biochemistry and Cell Biology , vol.38 , Issue.10 , pp. 1647-1653
    • Tergaonkar, V.1
  • 129
    • 41549114526 scopus 로고    scopus 로고
    • Xenobiotic-induced transcriptional regulation of xenobiotic metabolizing enzymes of the cytochrome P450 superfamily in human extrahepatic tissues
    • DOI 10.2174/138920008783571774
    • Pavek, P.; Dvorak, Z. Xenobiotic-induced transcriptional regulation of xenobiotic metabolizing enzymes of the cytochrome P450 superfamily in human extrahepatic tissues. Curr. Drug Metab., 2008, 9(2), 129-143. (Pubitemid 351461002)
    • (2008) Current Drug Metabolism , vol.9 , Issue.2 , pp. 129-143
    • Pavek, P.1    Dvorak, Z.2
  • 130
    • 79952037796 scopus 로고    scopus 로고
    • Single and concerted effects of benzo[a]pyrene and flavonoids on the ahr and nrf2-pathway in the human colon carcinoma cell line caco-2
    • Niestroy, J.; Barbara, A.; Herbst, K.; Rode, S.; van Liempt, M.; Roos, P.H. Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. Toxicol. In Vitro, 2011, 25(3), 671-683.
    • (2011) Toxicol. In Vitro , vol.25 , Issue.3 , pp. 671-683
    • Niestroy, J.1    Barbara, A.2    Herbst, K.3    Rode, S.4    Van Liempt, M.5    Roos, P.H.6
  • 131
    • 6344254478 scopus 로고    scopus 로고
    • Cytochrome P450 expression in human keratinocytes: An aryl hydrocarbon receptor perspective
    • DOI 10.1016/j.cbi.2004.08.006, PII S0009279704001073
    • Swanson, H.I. Cytochrome P450 expression in human keratinocytes: an aryl hydrocarbon receptor perspective. Chem. Biol. Interact., 2004, 149(2-3), 69-79. (Pubitemid 39387210)
    • (2004) Chemico-Biological Interactions , vol.149 , Issue.2-3 , pp. 69-79
    • Swanson, H.I.1
  • 132
    • 33748757740 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor and light
    • DOI 10.1515/BC.2006.143, PII BCHM38791149
    • Rannug, A.; Fritsche, E. The aryl hydrocarbon receptor and light. Biol. Chem., 2006, 387(9), 1149-1157. (Pubitemid 44402061)
    • (2006) Biological Chemistry , vol.387 , Issue.9 , pp. 1149-1157
    • Rannug, A.1    Fritsche, E.2
  • 133
    • 0034046957 scopus 로고    scopus 로고
    • Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1
    • DOI 10.1046/j.1523-1747.2000.00876.x
    • Katiyar, S.K.; Matsui, M.S.; Mukhtar, H. Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1. J. Invest. Dermatol., 2000, 114(2), 328-333. (Pubitemid 30417769)
    • (2000) Journal of Investigative Dermatology , vol.114 , Issue.2 , pp. 328-333
    • Katiyar, S.K.1    Matsui, M.S.2    Mukhtar, H.3
  • 134
    • 59149105791 scopus 로고    scopus 로고
    • The suggested physiologic aryl hydrocarbon receptor activator and cytochrome p450i substrate 6-formylindolo[3,2-b]carbazole is present in humans
    • Wincent, E.; Amini, N.; Luecke, S.; Glatt, H.; Bergman, J.; Crescenzi, C.; Rannug, A.; Rannug, U. The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P450I substrate 6-formylindolo[3,2-b]carbazole is present in humans. J. Biol. Chem., 2009, 284(5), 2690-2696.
    • (2009) J. Biol. Chem. , vol.284 , Issue.5 , pp. 2690-2696
    • Wincent, E.1    Amini, N.2    Luecke, S.3    Glatt, H.4    Bergman, J.5    Crescenzi, C.6    Rannug, A.7    Rannug, U.8
  • 135
    • 38949097735 scopus 로고    scopus 로고
    • The search for endogenous activators of the aryl hydrocarbon receptor
    • DOI 10.1021/tx7001965
    • Nguyen, L.P.; Bradfield, C.A. The search for endogenous activators of aryl hydrocarbon receptor. Chem. Res. Toxicol., 2008, 21(1), 102-116. (Pubitemid 351219712)
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.1 , pp. 102-116
    • Nguyen, L.P.1    Bradfield, C.A.2
  • 136
    • 79952792921 scopus 로고    scopus 로고
    • Endogenous and exogenous ligands of aryl hydrocarbon receptor: Current state of art
    • Stejskalova, L.; Dvorak, Z.; Pavek, P. Endogenous and exogenous ligands of aryl hydrocarbon receptor: current state of art. Curr. Drug Metab., 2011, 12(2), 198-212.
    • (2011) Curr. Drug Metab. , vol.12 , Issue.2 , pp. 198-212
    • Stejskalova, L.1    Dvorak, Z.2    Pavek, P.3
  • 137
    • 84865592635 scopus 로고    scopus 로고
    • Photo-oxidation products of skin surface squalene mediate metabolic and inflammatory responses to solar uv in human keratinocytes
    • Kostyuk, V.; Potapovich, A.; Stancato, A.; De Luca, C.; Lulli, D.; Pastore, S.; Korkina, L. Photo-oxidation products of skin surface squalene mediate metabolic and inflammatory responses to solar UV in human keratinocytes. PLoS One, 2012, 7(8), e44472.
    • (2012) PLoS One , vol.7 , Issue.8
    • Kostyuk, V.1    Potapovich, A.2    Stancato, A.3    De Luca, C.4    Lulli, D.5    Pastore, S.6    Korkina, L.7
  • 138
    • 79959462242 scopus 로고    scopus 로고
    • Impact of aryl hydrocarbon receptor (ahr) knockdown on cell cycle prograssion in human hacat keratinocytes
    • Kalmes, M.; Hennen, J.; Clemens, J.; Blomeke, B. Impact of aryl hydrocarbon receptor (AhR) knockdown on cell cycle prograssion in human HaCaT keratinocytes. Biol. Chem., 2011, 392(7), 643-651.
    • (2011) Biol. Chem. , vol.392 , Issue.7 , pp. 643-651
    • Kalmes, M.1    Hennen, J.2    Clemens, J.3    Blomeke, B.4
  • 139
    • 79957876145 scopus 로고    scopus 로고
    • Suppression of wif-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (ahr) overexpressing mcf10at1 breast cancer cells
    • Wu, D.; Wong, P.; Li, W.; Vogel, C.F.; Matsumura, F. Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. Toxicology, 2011, 285(3), 97-103.
    • (2011) Toxicology , vol.285 , Issue.3 , pp. 97-103
    • Wu, D.1    Wong, P.2    Li, W.3    Vogel, C.F.4    Matsumura, F.5
  • 140
    • 84863017101 scopus 로고    scopus 로고
    • Phtalates induce proliferation and invasiveness of estrogen receptornegative breast cancer through the ahr/hdac6/c-myc signaling pathway
    • Hsieh, T.H.; Tsai, C.F.; Hsu, C.Y.; Kuo, P.L.; Chai, C.Y.; Wang, S.C.; Tsai, E.M. Phtalates induce proliferation and invasiveness of estrogen receptornegative breast cancer through the AhR/HDAC6/c-Myc signaling pathway. FASEB J., 2012, 26(2), 778-787.
    • (2012) FASEB J , vol.26 , Issue.2 , pp. 778-787
    • Hsieh, T.H.1    Tsai, C.F.2    Hsu, C.Y.3    Kuo, P.L.4    Chai, C.Y.5    Wang, S.C.6    Tsai, E.M.7
  • 141
    • 84855301572 scopus 로고    scopus 로고
    • Dintinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines
    • Labrecque, M.P.; Takhar, M.K.; Hollingshead, B.D.; Prefontaine, G.G.; Perdew, G.H.; Beischlag, T.V. Dintinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines. PLoS One, 2012, 7(1), e29545.
    • (2012) PLoS One , vol.7 , Issue.1
    • Labrecque, M.P.1    Takhar, M.K.2    Hollingshead, B.D.3    Prefontaine, G.G.4    Perdew, G.H.5    Beischlag, T.V.6
  • 142
    • 84859982619 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor (ahr) contributes to the proliferation of human medulloblastoma cells
    • Dever, D.P.; Opanashuk, L.A. The aryl hydrocarbon receptor (AhR) contributes to the proliferation of human medulloblastoma cells. Mol. Pharmacol., 2012, 81(5), 669-678.
    • (2012) Mol. Pharmacol. , vol.81 , Issue.5 , pp. 669-678
    • Dever, D.P.1    Opanashuk, L.A.2
  • 143
    • 79954954342 scopus 로고    scopus 로고
    • Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine
    • Shimamoto, K.; Dewa, Y.; Ishii, Y.; Kemmochi, S.; Taniai, E.; Hayashi, H.; Imaoka, M.; Morita, R.; Kuwata, K.; Suzuki, K.; Shibutani, M.; Mitsumori, K. Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine. Toxicology, 2011, 283(2-3), 109-117.
    • (2011) Toxicology , vol.283 , Issue.2-3 , pp. 109-117
    • Shimamoto, K.1    Dewa, Y.2    Ishii, Y.3    Kemmochi, S.4    Taniai, E.5    Hayashi, H.6    Imaoka, M.7    Morita, R.8    Kuwata, K.9    Suzuki, K.10    Shibutani, M.11    Mitsumori, K.12
  • 144
    • 79958093013 scopus 로고    scopus 로고
    • Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptor
    • Brooks, J.; Eltom, S.E. Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptor. Curr. Cancer Drug Targets, 2011, 11(5), 654-669.
    • (2011) Curr. Cancer Drug Targets , vol.11 , Issue.5 , pp. 654-669
    • Brooks, J.1    Eltom, S.E.2
  • 147
    • 84879464054 scopus 로고    scopus 로고
    • Expression of the aryl hydrocarbon receptor is not required for the
    • doi: 10.1002/mc.21889
    • Spink, B.C.; Bennett, J.A.; Lostritto, N.; Cole, J.R.; Spink, D.C. Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells. Mol. Carcinog., 2012, doi: 10.1002/mc.21889.
    • (2012) Mol. Carcinog.
    • Spink, B.C.1    Bennett, J.A.2    Lostritto, N.3    Cole, J.R.4    Spink, D.C.5
  • 148
    • 81855190624 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by tcdd inhibits mammary tumor metastasis in a syngeneic mouse model of breast cancer
    • Wang, T.; Wyrick, K.L.; Meadows, G.G.; Wills, T.B.; Vorderstrasse, B.A. Activation of the aryl hydrocarbon receptor by TCDD inhibits mammary tumor metastasis in a syngeneic mouse model of breast cancer. Toxicol. Sci., 2011, 124(2), 291-298.
    • (2011) Toxicol. Sci. , vol.124 , Issue.2 , pp. 291-298
    • Wang, T.1    Wyrick, K.L.2    Meadows, G.G.3    Wills, T.B.4    Vorderstrasse, B.A.5
  • 149
    • 77956173985 scopus 로고    scopus 로고
    • Suppression mechanisms of flavonoids on aryl hydrocarbon receptormediated signal transduction
    • Mukai, R.; Shirai, Y.; Saito, N.; Fukuda, I.; Nishiumi, S.; Yoshida, K.; Ashida, H. Suppression mechanisms of flavonoids on aryl hydrocarbon receptormediated signal transduction. Arch. Biochem. Biophys., 2010, 501(1), 134-141.
    • (2010) Arch. Biochem. Biophys. , vol.501 , Issue.1 , pp. 134-141
    • Mukai, R.1    Shirai, Y.2    Saito, N.3    Fukuda, I.4    Nishiumi, S.5    Yoshida, K.6    Ashida, H.7
  • 150
    • 77949275110 scopus 로고    scopus 로고
    • Dietary flavonoids in cancer therapy and prevention: Substrates and inhibitors of cytochrome p450 cyp1 enzymes
    • Androutsopoulos, V.P.; Papakyriakou, A.; Vourloumis, D.; Tsatsakis, A.M.; Spandidos, D.A. Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes. Pharmacol. Ther., 2010, 126(1), 9-20.
    • (2010) Pharmacol. Ther. , vol.126 , Issue.1 , pp. 9-20
    • Androutsopoulos, V.P.1    Papakyriakou, A.2    Vourloumis, D.3    Tsatsakis, A.M.4    Spandidos, D.A.5
  • 152
    • 0032535055 scopus 로고    scopus 로고
    • Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor
    • Ciolino, H.P.; Daschner, P.J.; Yeh, G.C. Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor. Cancer Res., 1998, 58(24), 5707-5712. (Pubitemid 29006410)
    • (1998) Cancer Research , vol.58 , Issue.24 , pp. 5707-5712
    • Ciolino, H.P.1    Daschner, P.J.2    Yeh, G.C.3
  • 153
    • 67649221173 scopus 로고    scopus 로고
    • Resveratrol inhibits dioxin-induced expression of human cyp1a1 and cyp1b1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and rna polymerase ii to the regulatory regions of the corresponding genes
    • Beedanagari, S.R.; Bebenek, I.; Bui, P.; Hankinson, O. Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes. Toxicol. Sci., 2009, 110(1), 61-67.
    • (2009) Toxicol. Sci. , vol.110 , Issue.1 , pp. 61-67
    • Beedanagari, S.R.1    Bebenek, I.2    Bui, P.3    Hankinson, O.4
  • 154
    • 0033564553 scopus 로고    scopus 로고
    • Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
    • DOI 10.1042/0264-6021:3400715
    • Ciolino, H.P.; Daschner, P.J.; Yeh, G.C. Dietary flavonols quercetin and kaemferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially. Biochem. J., 1999, 340(3), 715-722. (Pubitemid 29312869)
    • (1999) Biochemical Journal , vol.340 , Issue.3 , pp. 715-722
    • Ciolino, H.P.1    Daschner, P.J.2    Yeh, G.C.3
  • 155
    • 70349297460 scopus 로고    scopus 로고
    • Modulation of cyp1b1 and cyp1a1 gene expression and activation of aryl hydrocarbon receptor by ginkgo biloba extract in mcf-10a human mammary epithelial cells
    • Rajaraman, G.; Yang, G.; Chen, J.; Chang, T.K.H. Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells. Can. J. Physiol. Pharmacol., 2009, 87(9), 674-683.
    • (2009) Can. J. Physiol. Pharmacol. , vol.87 , Issue.9 , pp. 674-683
    • Rajaraman, G.1    Yang, G.2    Chen, J.3    Chang, T.K.H.4
  • 156
    • 34047191433 scopus 로고    scopus 로고
    • Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation
    • DOI 10.1093/carcin/bgl169
    • Puppala, D.; Gairola, C.G.; Swanson, H.I. Identification of kaemferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation. Carcinogenesis, 2007, 28(3), 639-647. (Pubitemid 46523359)
    • (2007) Carcinogenesis , vol.28 , Issue.3 , pp. 639-647
    • Puppala, D.1    Gairola, C.G.2    Swanson, H.I.3
  • 157
    • 0033009907 scopus 로고    scopus 로고
    • Regulation of interleukin-8 gene expression
    • DOI 10.1089/107999099313866
    • Roebuck, K.A. Regulation of interleukin-8 gene expression. J. Interferon Cytokine Res., 1999, 19(5), 429-438. (Pubitemid 29269932)
    • (1999) Journal of Interferon and Cytokine Research , vol.19 , Issue.5 , pp. 429-438
    • Roebuck, K.A.1
  • 160
    • 59149096524 scopus 로고    scopus 로고
    • Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (ahr) signaling pathways
    • Haarmann-Stemmann, T.; Both, H.; Abel, J. Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways. Biochem. Pharmacol., 2009, 77(4), 508-520.
    • (2009) Biochem. Pharmacol. , vol.77 , Issue.4 , pp. 508-520
    • Haarmann-Stemmann, T.1    Both, H.2    Abel, J.3
  • 162
    • 77956479430 scopus 로고    scopus 로고
    • Cutaneous epidermal growth factor receptor system following ultraviolet irradiation: Exploring the role of molecular mechanisms
    • Martinez-Carpio, P.A.; Trelles, M.A. Cutaneous epidermal growth factor receptor system following ultraviolet irradiation: exploring the role of molecular mechanisms. Photodermatol. Photoimmunol. Photomed., 2010, 26(5), 250-256.
    • (2010) Photodermatol. Photoimmunol. Photomed. , vol.26 , Issue.5 , pp. 250-256
    • Martinez-Carpio, P.A.1    Trelles, M.A.2
  • 163
    • 77949901726 scopus 로고    scopus 로고
    • Interaction between oxidative stress sensor nrf2 and xenobiotic-Activated aryl hydrocarbon receptor in the regulation of the human phase ii detoxifying udpglucuronosyltransferase 1a10
    • Kalthoff, S.; Ehmer, U.; Freiberg, N.; Manns, M.P.; Strassburg, C.P. Interaction between oxidative stress sensor Nrf2 and xenobiotic-Activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDPglucuronosyltransferase 1A10. J. Biol. Chem., 2010, 285(9), 5993-6002.
    • (2010) J. Biol. Chem. , vol.285 , Issue.9 , pp. 5993-6002
    • Kalthoff, S.1    Ehmer, U.2    Freiberg, N.3    Manns, M.P.4    Strassburg, C.P.5
  • 164
    • 59149097969 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor cross-Talks with multiple signal transduction pathways
    • Puga, A.; Ma, C.; Marlowe, J.L. The aryl hydrocarbon receptor cross-Talks with multiple signal transduction pathways. Biochem. Pharmacol., 2009, 77(4), 13-22.
    • (2009) Biochem. Pharmacol. , vol.77 , Issue.4 , pp. 13-22
    • Puga, A.1    Ma, C.2    Marlowe, J.L.3
  • 166
    • 52449117077 scopus 로고    scopus 로고
    • Micro rna epigenetic alterations: Predicting biomarkers and therapeutic targets in human diseases
    • Wang, Y.; Liang, Y.; Lu, Q. Micro RNA epigenetic alterations: predicting biomarkers and therapeutic targets in human diseases. Clin. Genet., 2008, 74(4), 307-315.
    • (2008) Clin. Genet. , vol.74 , Issue.4 , pp. 307-315
    • Wang, Y.1    Liang, Y.2    Lu, Q.3
  • 167
    • 84860275721 scopus 로고    scopus 로고
    • Epigenetic impact of dietary polyphenols in cancer chemoprevention: Lifelong remodeling of our epigenomes
    • Vanden Berghe, W. Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes. Pharmacol. Res., 2012, 65(6), 565-576.
    • (2012) Pharmacol. Res. , vol.65 , Issue.6 , pp. 565-576
    • Vanden Berghe, W.1
  • 168
    • 78049440083 scopus 로고    scopus 로고
    • Nature or nurture: Let food be your epigenetic medicine in chronic inflammatory disorders
    • Szarc vel Szic, K.; Ndlovu, M.N.; Haegeman, G.; Vanden Berghe, W. Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders. Biochem. Pharmacol., 2010, 80(12), 1816-1832.
    • (2010) Biochem. Pharmacol. , vol.80 , Issue.12 , pp. 1816-1832
    • Szarc Vel Szic, K.1    Ndlovu, M.N.2    Haegeman, G.3    Berghe, V.W.4
  • 169
    • 80052009897 scopus 로고    scopus 로고
    • Epigenetic diet: Impact on the epigenome and cancer
    • Hardy, T.M.; Tollefsbol, T.O. Epigenetic diet: impact on the epigenome and cancer. Epigenomics, 2011, 3(4), 503-518.
    • (2011) Epigenomics , vol.3 , Issue.4 , pp. 503-518
    • Hardy, T.M.1    Tollefsbol, T.O.2
  • 170
    • 61549106928 scopus 로고    scopus 로고
    • Epigenetics and dermatological disease
    • Millington, G. W. Epigenetics and dermatological disease. Pharmacogenomics, 2008, 9(12), 1835-1850.
    • (2008) Pharmacogenomics , vol.9 , Issue.12 , pp. 1835-1850
    • Millington, G.1
  • 174
    • 40749111551 scopus 로고    scopus 로고
    • A skin microRNA promotes differentiation by repressing 'stemness'
    • DOI 10.1038/nature06642, PII NATURE06642
    • Yi, R.; Poy, M. N.; Stoffel, M.; Fuchs, E. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 2008, 452(7184), 225-229. (Pubitemid 351380241)
    • (2008) Nature , vol.452 , Issue.7184 , pp. 225-229
    • Yi, R.1    Poy, M.N.2    Stoffel, M.3    Fuchs, E.4
  • 175
    • 78049429911 scopus 로고    scopus 로고
    • Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics
    • Link, A.; Balaguer; F., Goel, A. Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics. Biochem. Pharmacol., 2010, 80(12), 1771-1792.
    • (2010) Biochem. Pharmacol. , vol.80 , Issue.12 , pp. 1771-1792
    • Link, A.1    Balaguer, F.2    Goel, A.3
  • 176
    • 48349123382 scopus 로고    scopus 로고
    • The bmi-1 polycomb group gene in skin cancer: Regulation of function by (-)-epigallocatechin-3-gallate
    • Balasubramanian, S.; Lee, K.; Adhikary, G.; Gopalakrishnan, R.; Rorke, E. A.; Eckert, R. L., The Bmi-1 polycomb group gene in skin cancer: regulation of function by (-)-epigallocatechin-3-gallate. Nutr Rev 2008, 66 (Suppl 1), S65-S68.
    • (2008) Nutr Rev , vol.66 , Issue.SUPPL. 1
    • Balasubramanian, S.1    Lee, K.2    Adhikary, G.3    Gopalakrishnan, R.4    Rorke, E.A.5    Eckert, R.L.6
  • 177
    • 79953692105 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes Cip1/p21 and p16INK4a by reducing DNA methylation and increasing histone acetylation in human skin cancer cells
    • Nandakumar, V.; vaid, M.; Katiyar, S.K. (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histone acetylation in human skin cancer cells. Carcinogenesis, 2011, 32(4), 537-544.
    • (2011) Carcinogenesis , vol.32 , Issue.4 , pp. 537-544
    • Nandakumar, V.1    Vaid, M.2    Katiyar, S.K.3
  • 178
    • 84864139600 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators
    • Vaid, M.; Prasad, R.; Singh, T.; Jones, V.; Katiyar, S.K. Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators. Toxicol. Appl. Pharmacol., 2012, 263(1), 122-130.
    • (2012) Toxicol. Appl. Pharmacol. , vol.263 , Issue.1 , pp. 122-130
    • Vaid, M.1    Prasad, R.2    Singh, T.3    Jones, V.4    Katiyar, S.K.5
  • 179
    • 55449104382 scopus 로고    scopus 로고
    • The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases
    • Olaharski, A. J.; Rine, J.; Marshall, B. L.; Babiarz, J.; Zhang, L.; Verdin, E.; Smith, M. T., The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. PLoS Genet 2005, 1(6), e77.
    • (2005) PLoS Genet , vol.1 , Issue.6
    • Olaharski, A.J.1    Rine, J.2    Marshall, B.L.3    Babiarz, J.4    Zhang, L.5    Verdin, E.6    Smith, M.T.7
  • 180
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang, M.; Chen, D.; Yang, C.S. Dietary polyphenols may affect DNA methylation. J. Nutr., 2007, 137(1), 223S-228S. (Pubitemid 46052885)
    • (2007) Journal of Nutrition , vol.137 , Issue.1
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 181
    • 77955621544 scopus 로고    scopus 로고
    • Impact on dna methylation in cancer prevention and therapy by bioactive dietary components
    • Li, Y.; Tollefsbol, T.O. Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr. Med. Chem., 2010, 17(20), 2141-2151.
    • (2010) Curr. Med. Chem. , vol.17 , Issue.20 , pp. 2141-2151
    • Li, Y.1    Tollefsbol, T.O.2
  • 182
    • 77953198124 scopus 로고    scopus 로고
    • Regulation of micrornas by natural agents: An emerging field in chemoprevention and chemotherapy research
    • Li, Y.; Kong, D.; Wang, Z.; Sarkar, F.H. Regulation of microRNAs by Natural Agents: An Emerging Field in Chemoprevention and Chemotherapy Research. Pharm. Res., 2010, 27(6), 1027-1041.
    • (2010) Pharm. Res. , vol.27 , Issue.6 , pp. 1027-1041
    • Li, Y.1    Kong, D.2    Wang, Z.3    Sarkar, F.H.4
  • 183
    • 49549087270 scopus 로고    scopus 로고
    • Effects of green tea polyphenol on methylation status of reck gene and cancer cell invasion in oral squamous cell carcinoma cells
    • Kato, K; Long, N.K.; Makita, H.; Toida, M.; Yamashita, T.; Hatakeyama, D.; Hara, A.; Mori, H.; Shibata, T. Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells. Br. J. Cancer, 2008, 99(4), 647-654.
    • (2008) Br. J. Cancer , vol.99 , Issue.4 , pp. 647-654
    • Kato, K.1    Long, N.K.2    Makita, H.3    Toida, M.4    Yamashita, T.5    Hatakeyama, D.6    Hara, A.7    Mori, H.8    Shibata, T.9
  • 184
    • 77950907191 scopus 로고    scopus 로고
    • The bmi-1 polycomb protein antagonizes the (2)-epigallocatechin-3- gallate-dependent suppression of skin cancer cell survival
    • Balasubramanian, S.; Adhikary, G.; Eckert, R.L. The Bmi-1 polycomb protein antagonizes the (2)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival. Carcinogenesis, 2010, 31(3), 496-503.
    • (2010) Carcinogenesis , vol.31 , Issue.3 , pp. 496-503
    • Balasubramanian, S.1    Adhikary, G.2    Eckert, R.L.3
  • 187
    • 28844492580 scopus 로고    scopus 로고
    • Chemosensitization and radiosensitization of tumors by plant polyphenols
    • DOI 10.1089/ars.2005.7.1630
    • Garg, A.K.; Buchholz, T.A.; Aggarwal, B.B. Chemosensitization and radiosensitization of tumors by plant polyphenols. Antioxid. Redox Signal., 2005, 7(11-12), 1630-1647. (Pubitemid 41767998)
    • (2005) Antioxidants and Redox Signaling , vol.7 , Issue.11-12 , pp. 1630-1647
    • Garg, A.K.1    Buchholz, T.A.2    Aggarwal, B.B.3
  • 188
    • 0037427122 scopus 로고    scopus 로고
    • NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells
    • DOI 10.1038/sj.onc.1206056
    • Bentires-Alj, M.; Barbu, V.; Fillet, M.; Chariot, A.; Relic, B.; Jacobs, N.; Gielen, J.; Merville, M.P.; Bours, V. NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 2003, 22(1), 90-97. (Pubitemid 36152887)
    • (2003) Oncogene , vol.22 , Issue.1 , pp. 90-97
    • Bentires-Alj, M.1    Barbu, V.2    Fillet, M.3    Chariot, A.4    Relic, B.5    Jacobs, N.6    Gielen, J.7    Merville, M.-P.8    Bours, V.9
  • 189
    • 54049147251 scopus 로고    scopus 로고
    • Reversal effect of resveratrol on multidrug resistance in kbv200 cell line
    • Quan, F.; Pan, C.; Ma, Q.; Zhang, S.; Yan, L. Reversal effect of resveratrol on multidrug resistance in KBv200 cell line. Biomed. Pharmacother., 2008, 62(9), 622-629.
    • (2008) Biomed. Pharmacother. , vol.62 , Issue.9 , pp. 622-629
    • Quan, F.1    Pan, C.2    Ma, Q.3    Zhang, S.4    Yan, L.5
  • 191
    • 79957607992 scopus 로고    scopus 로고
    • Molecular pathways for cancer chemoprevention by dietary phytochemicals
    • Tan, A.C.; Konczak, I.; Sze, D.M.; Ramzan, I. Molecular pathways for cancer chemoprevention by dietary phytochemicals. Nutr. Cancer, 2011, 63(4), 495-505.
    • (2011) Nutr. Cancer , vol.63 , Issue.4 , pp. 495-505
    • Tan, A.C.1    Konczak, I.2    Sze, D.M.3    Ramzan, I.4
  • 192
    • 84862872262 scopus 로고    scopus 로고
    • Effects of geranyl-phloroacetophenone on the induction of apoptosis and chemosensitization of adriamycin-resistant mcf-7 human breast cancer cells
    • Cho, M.Y.; Park, S.Y.; Park, S.; Lee, Y.R.; Kwak, M.K.; Kim, J.A. Effects of geranyl-phloroacetophenone on the induction of apoptosis and chemosensitization of adriamycin-resistant MCF-7 human breast cancer cells. Arch. Pharm. Res., 2012, 35(5), 911-919.
    • (2012) Arch. Pharm. Res. , vol.35 , Issue.5 , pp. 911-919
    • Cho, M.Y.1    Park, S.Y.2    Park, S.3    Lee, Y.R.4    Kwak, M.K.5    Kim, J.A.6
  • 193
    • 45749090051 scopus 로고    scopus 로고
    • Theaflavin-3-gallate and theaflavin-3-gallate, polyphenols in black tea with prooxidant properties
    • DOI 10.1111/j.1742-7843.2008.00232.x
    • Babich, H.; Gottesman, R.T.; Liebling, E.J.; Schuck, A.G. Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant properties. Basic Clin. Pharmacol. Toxicol., 2008, 103(1), 66-74. (Pubitemid 351874530)
    • (2008) Basic and Clinical Pharmacology and Toxicology , vol.103 , Issue.1 , pp. 66-74
    • Babich, H.1    Gottesman, R.T.2    Liebling, E.J.3    Schuck, A.G.4
  • 194
    • 33845224136 scopus 로고    scopus 로고
    • The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin
    • DOI 10.1016/j.fct.2006.07.027, PII S0278691506002407
    • Hayeshi, R.; Mutingwende, I.; Mavengere, W.; Masiyanise, V.; Mukanganyama, S. The inhibition of human glutathione S-Transferases activity by plant polyphenolic compounds ellagic acid and curcumin. Food Chem. Toxicol., 2007, 45(2), 286-295. (Pubitemid 44854313)
    • (2007) Food and Chemical Toxicology , vol.45 , Issue.2 , pp. 286-295
    • Hayeshi, R.1    Mutingwende, I.2    Mavengere, W.3    Masiyanise, V.4    Mukanganyama, S.5
  • 195
    • 77954090603 scopus 로고    scopus 로고
    • Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant b16 melanoma
    • Gatouillat, G.; Balasse, E.; Joseph-Pietras, D.; Morjani, H.; Madoulet, C. Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma. J. Cell. Biochem., 2010, 110(4), 893-902.
    • (2010) J. Cell. Biochem. , vol.110 , Issue.4 , pp. 893-902
    • Gatouillat, G.1    Balasse, E.2    Joseph-Pietras, D.3    Morjani, H.4    Madoulet, C.5
  • 196
    • 33947197883 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells
    • DOI 10.1182/blood-2006-02-003988
    • Bhardwaj, A.; Sethi, G.; Vadhan-Raj, S.; Bueso-Ramos, C.; Takada, Y.; Gaur, U.; Nair, A.S.; Shishodia, S.; Aggarwal, B,B. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through downregulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood, 2007; 109(6), 2293-2302. (Pubitemid 46425866)
    • (2007) Blood , vol.109 , Issue.6 , pp. 2293-2302
    • Bhardwaj, A.1    Sethi, G.2    Vadhan-Raj, S.3    Bueso-Ramos, C.4    Takada, Y.5    Gaur, U.6    Nair, A.S.7    Shishodia, S.8    Aggarwal, B.B.9
  • 198
    • 34249893102 scopus 로고    scopus 로고
    • Resveratrol sensitization of DU145 prostate cancer cells to ionizing radiation is associated to ceramide increase
    • DOI 10.1016/j.canlet.2007.01.014, PII S0304383507000328
    • Scarlatti, F.; Sala, G.; Ricci, C.; Maioli, C.; Milani, F.; Minella, M.; Botturi, M.; Ghidoni, R. Resveratrol sensitization of DU145 prostate cancer cells to ionizing radiation is associated to ceramide increase. Cancer Lett., 2007, 253(1), 124-130. (Pubitemid 46874732)
    • (2007) Cancer Letters , vol.253 , Issue.1 , pp. 124-130
    • Scarlatti, F.1    Sala, G.2    Ricci, C.3    Maioli, C.4    Milani, F.5    Minella, M.6    Botturi, M.7    Ghidoni, R.8
  • 199
    • 33847610748 scopus 로고    scopus 로고
    • The proteasome as a potential target for novel anticancer drugs and chemosensitizers
    • DOI 10.1016/j.drup.2006.11.001, PII S1368764606000781
    • Landis-Piwowar, K.R.; Milacic, V.; Chen, D.; Yang, H.; Zhao, Y.; Chan, T.H.; Yan, B.; Dou, Q.P. The proteasome as a potential target for novel anticancer drugs and chemosensitizers. Drug. Resist. Updat., 2006, 9(6), 263-273. (Pubitemid 46357634)
    • (2006) Drug Resistance Updates , vol.9 , Issue.6 , pp. 263-273
    • Landis-Piwowar, K.R.1    Milacic, V.2    Chen, D.3    Yang, H.4    Zhao, Y.5    Chan, T.H.6    Yan, B.7    Dou, Q.P.8
  • 200
    • 84866355972 scopus 로고    scopus 로고
    • Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization
    • Epub ahead of print, Jan 31
    • Shen, M.; Chan, T.H.; Dou, Q.P. Targeting Tumor Ubiquitin-Proteasome Pathway with Polyphenols for Chemosensitization. Anticancer Agents Med. Chem., 2012, Epub ahead of print, Jan 31.
    • (2012) Anticancer Agents Med. Chem.
    • Shen, M.1    Chan, T.H.2    Dou, Q.P.3
  • 201
    • 74349115989 scopus 로고    scopus 로고
    • Apigenin Chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells
    • Wu, Y.X.; Fang, X. Apigenin, Chrysin, and Luteolin Selectively Inhibit Chymotrypsin-Like and Trypsin-Like Proteasome Catalytic Activities in Tumor Cells. Planta Med., 2010, 76(2), 128-132.
    • (2010) Planta Med. , vol.76 , Issue.2 , pp. 128-132
    • Wu, Y.X.1    Fang, X.2
  • 202
    • 79951702955 scopus 로고    scopus 로고
    • Bortezomib as the first proteasome inhibitor anticancer drug: Current status and future perspectives d
    • Chen, D.; Frezza, M.; Schmitt, S.; Kanwar, J.; Dou, Q.P. Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives D. Curr. Cancer Drug Targets. 2011, 11(3): 239-253.
    • (2011) Curr. Cancer Drug Targets. , vol.11 , Issue.3 , pp. 239-253
    • Chen, D.1    Frezza, M.2    Schmitt, S.3    Kanwar, J.4    Dou, Q.P.5
  • 203
    • 47349100951 scopus 로고    scopus 로고
    • Natural compounds with proteasome inhibitory activity for cancer prevention and treatment
    • DOI 10.2174/138920308784533998
    • Yang, H.; Landis-Piwowar, K.R.; Chen, D.; Milacic, V.; Dou, Q.P. Natural Compounds with Proteasome Inhibitory Activity for Cancer Prevention and Treatment. Curr. Protein Pept. Sci., 2008, 9(3), 227-239. (Pubitemid 351997839)
    • (2008) Current Protein and Peptide Science , vol.9 , Issue.3 , pp. 227-239
    • Yang, H.1    Landis-Piwowar, K.R.2    Chen, D.3    Milacic, V.4    Dou, Q.P.5
  • 204
    • 33744832401 scopus 로고    scopus 로고
    • United States Food and Drug Administration approval summary: Bortezomib for the treatment of progressive multiple myeloma after one prior therapy
    • DOI 10.1158/1078-0432.CCR-06-0170
    • Kane, R.C.; Farrell, A.T.; Sridhara, R.; Pazdur, R. United States Food and Drug Administration approval summary: bortezomib for the treatment of progressive multiple myeloma after one prior therapy. Clin. Cancer Res., 2006, 12(10), 2955-2960. (Pubitemid 43837337)
    • (2006) Clinical Cancer Research , vol.12 , Issue.10 , pp. 2955-2960
    • Kane, R.C.1    Farrell, A.T.2    Sridhara, R.3    Pazdur, R.4
  • 206
    • 22244454745 scopus 로고    scopus 로고
    • Differential regulation of Noxa in normal melanocytes and melanoma cells by proteasome inhibition: Therapeutic implications
    • DOI 10.1158/0008-5472.CAN-05-0686
    • Fernández, Y.; Verhaegen, M.; Miller, T.P.; Rush, J.L.; Steiner, P.; Opipari, A.W.Jr.; Lowe, S.W.; Soengas, M.S. Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. Cancer Res., 2005, 65(14), 6294-6304. (Pubitemid 40994415)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6294-6304
    • Fernandez, Y.1    Verhaegen, M.2    Miller, T.P.3    Rush, J.L.4    Steiner, P.5    Opipari Jr., A.W.6    Lowe, S.W.7    Soengas, M.S.8
  • 208
    • 64849104336 scopus 로고    scopus 로고
    • Design and synthesis of a gossypol derivative with improved antitumor activities
    • Zhan, Y.; Jia, G.; Wu, D.; Xu, Y.; Xu, L. Design and Synthesis of a Gossypol Derivative with Improved Antitumor Activities. Arch. Pharm. Chem. Life Sci., 2009, 342(4), 223-229.
    • (2009) Arch. Pharm. Chem. Life Sci. , vol.342 , Issue.4 , pp. 223-229
    • Zhan, Y.1    Jia, G.2    Wu, D.3    Xu, Y.4    Xu, L.5
  • 210
    • 84866741435 scopus 로고    scopus 로고
    • The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of noxa-dependent apoptosis
    • Cabello, C.M.; Lamore, S.D.; Bair, W.B.3rd; Qiao, S.; Azimian, S.; Lesson, J.L.; Wondrak, G.T. The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis. Invest. New Drugs, 2012, 30(4), 1289-1301.
    • (2012) Invest. New Drugs , vol.30 , Issue.4 , pp. 1289-1301
    • Cabello, C.M.1    Lamore, S.D.2    Bair III, W.B.3    Qiao, S.4    Azimian, S.5    Lesson, J.L.6    Wondrak, G.T.7
  • 212
    • 78650994500 scopus 로고    scopus 로고
    • Egcg green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment
    • Chen, D., Wan, S.B.; Yang, H.; Yuan, J.; Chan, T.H.; Dou, Q.P. EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment. Adv. Clin. Chem., 2011, 53, 155-177.
    • (2011) Adv. Clin. Chem. , vol.53 , pp. 155-177
    • Chen, D.1    Wan, S.B.2    Yang, H.3    Yuan, J.4    Chan, T.H.5    Dou, Q.P.6
  • 213
    • 77950793297 scopus 로고    scopus 로고
    • Combined effects of the proteasome inhibitor bortezomib and hsp70 inhibitors on the b16f10 melanoma cell line
    • Yerlikaya, A.; Okur, E.; Eker, S.; Erin, N. Combined effects of the proteasome inhibitor bortezomib and Hsp70 inhibitors on the B16F10 melanoma cell line. Mol. Med. Report, 2010, 3(2), 333-339.
    • (2010) Mol. Med. Report , vol.3 , Issue.2 , pp. 333-339
    • Yerlikaya, A.1    Okur, E.2    Eker, S.3    Erin, N.4
  • 215
    • 82055185038 scopus 로고    scopus 로고
    • The gluttonous side of malignant melanoma: Basic and clinical implications of macroautophagy
    • Checinska, A.; Soengas, M.S. The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy. Pigment Cell Melanoma Res., 2011, 24(6), 1116-1132.
    • (2011) Pigment Cell Melanoma Res. , vol.24 , Issue.6 , pp. 1116-1132
    • Checinska, A.1    Soengas, M.S.2
  • 216
    • 77950509348 scopus 로고    scopus 로고
    • Autophagy and tumorigenesis
    • Chen, N., Debnath, J. Autophagy and tumorigenesis. FEBS Lett., 2010, 584(7), 1427-1435.
    • (2010) FEBS Lett. , vol.584 , Issue.7 , pp. 1427-1435
    • Chen, N.1    Debnath, J.2
  • 218
    • 69549119876 scopus 로고    scopus 로고
    • Melanomas display increased cytoprotection to hypericin-mediated cytotoxicity through the induction of autophagy
    • Davids, L.M.; Kleemann, B.; Cooper, S.; Kidson, S.H. Melanomas display increased cytoprotection to hypericin-mediated cytotoxicity through the induction of autophagy. Cell Biol. Int., 2009, 33(10), 1065-1072.
    • (2009) Cell Biol. Int. , vol.33 , Issue.10 , pp. 1065-1072
    • Davids, L.M.1    Kleemann, B.2    Cooper, S.3    Kidson, S.H.4
  • 219
    • 34447092454 scopus 로고    scopus 로고
    • Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells
    • DOI 10.1093/carcin/bgl232
    • Psahoulia, F.H.; Moumtzi, S.; Roberts, M.L.; Sasazuki, T.; Shirasawa, S.; Pintzas, A. Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-Transformed human colon cells. Carcinogenesis, 2007, 28(5), 1021-1031. (Pubitemid 47072186)
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 1021-1031
    • Psahoulia, F.H.1    Moumtzi, S.2    Roberts, M.L.3    Sasazuki, T.4    Shirasawa, S.5    Pintzas, A.6
  • 220
    • 79952801721 scopus 로고    scopus 로고
    • Resveratrol a phytochemical inducer of multiple cell death pathways: Apoptosis, autophagy and mitotic catastrophe
    • Delmas, D.; Solary, E.; Latruffe, N. Resveratrol, a Phytochemical Inducer of Multiple Cell Death Pathways: Apoptosis, Autophagy and Mitotic Catastrophe. Curr. Med. Chem., 2011, 18(8), 1100-1121.
    • (2011) Curr. Med. Chem. , vol.18 , Issue.8 , pp. 1100-1121
    • Delmas, D.1    Solary, E.2    Latruffe, N.3
  • 221
    • 78649630983 scopus 로고    scopus 로고
    • Resveratrol and cardiovascular health
    • Das, M.; Das, D.K. Resveratrol and cardiovascular health. Mol. Aspects Med., 2010, 31(6), 503-512.
    • (2010) Mol. Aspects Med. , vol.31 , Issue.6 , pp. 503-512
    • Das, M.1    Das, D.K.2
  • 222
    • 34250372159 scopus 로고    scopus 로고
    • Radiosensitization of tumour cell lines by the polyphenol Gossypol results from depressed double-strand break repair and not from enhanced apoptosis
    • DOI 10.1016/j.radonc.2007.04.024, PII S0167814007001715, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
    • Kasten-Pisula, U.; Windhorst, S.; Dahm-Daphi, J.; Mayr, G.; Dikomey, E. Radiosensitization of tumor cell lines by the polyphenol Gossypol results from depressed double-strand break repair and not from enhanced apoptosis. Radiother. Oncol., 2007, 83(3), 296-303. (Pubitemid 46915544)
    • (2007) Radiotherapy and Oncology , vol.83 , Issue.3 , pp. 296-303
    • Kasten-Pisula, U.1    Windhorst, S.2    Dahm-Daphi, J.3    Mayr, G.4    Dikomey, E.5
  • 224
    • 79952692497 scopus 로고    scopus 로고
    • Green tea prevents non-melanoma skin cancer by enhancing dna repair
    • Katiyar, S.K. Green tea prevents non-melanoma skin cancer by enhancing DNA repair. Arch. Biochem. Biophys., 2011, 508(2): 152-158.
    • (2011) Arch. Biochem. Biophys. , vol.508 , Issue.2 , pp. 152-158
    • Katiyar, S.K.1
  • 225
    • 84877943062 scopus 로고    scopus 로고
    • History of phototherapy in dermatology
    • Epub ahead of print, Jun 27
    • Hönigsmann, H. History of phototherapy in dermatology. Photochem. Photobiol. Sci., 2012, Epub ahead of print, Jun 27.
    • (2012) Photochem. Photobiol. Sci.
    • Hönigsmann, H.1
  • 226
    • 84859708867 scopus 로고    scopus 로고
    • Photodynamic therapy: Current evidence and applications in dermatology
    • Lee, Y.; Baron, E.D. Photodynamic therapy: current evidence and applications in dermatology. Semin. Cutan. Med. Surg., 2011, 30(4), 199-209.
    • (2011) Semin. Cutan. Med. Surg. , vol.30 , Issue.4 , pp. 199-209
    • Lee, Y.1    Baron, E.D.2
  • 227
    • 84858335295 scopus 로고    scopus 로고
    • Puva follow-up study. The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet a therapy: A 30-year prospective study
    • Stern, R.S. PUVA follow-up study. The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: a 30-year prospective study. J. Am. Acad. Dermatol., 2012, 66(4), 553-562.
    • (2012) J. Am. Acad. Dermatol. , vol.66 , Issue.4 , pp. 553-562
    • Stern, R.S.1
  • 229
    • 84858285142 scopus 로고    scopus 로고
    • The role of extracorporeal photopheresis in the treatment of cutaneous t-cell lymphomas
    • Atta, M.; Papanicolaou, N.; Tsirigotis, P. The role of extracorporeal photopheresis in the treatment of cutaneous T-cell lymphomas. Transfus. Apher. Sci., 2012, 46(2), 195-202.
    • (2012) Transfus. Apher. Sci. , vol.46 , Issue.2 , pp. 195-202
    • Atta, M.1    Papanicolaou, N.2    Tsirigotis, P.3
  • 230
    • 0031148463 scopus 로고    scopus 로고
    • Photophysical and photobiological processes in the photodynamic therapy of tumours
    • DOI 10.1016/S1011-1344(96)07428-3, PII S1011134496074283
    • Ochsner, M. Photophysical and photobiological processes in the photodynamic therapy of tumors. J. Photochem. Photobiol. B., 1997, 39(1), 1-18. (Pubitemid 27285576)
    • (1997) Journal of Photochemistry and Photobiology B: Biology , vol.39 , Issue.1 , pp. 1-18
    • Ochsner, M.1
  • 233
    • 84655169764 scopus 로고    scopus 로고
    • Cachrys pungens jan inhibits human melanoma cell proliferation through photo-induced cytotoxic activity
    • Menichini, G.; Alfano, C.; Provenzano, E.; Marrelli, M.; Statti, G.A.; Menichini, F.; Conforti, F. Cachrys pungens Jan inhibits human melanoma cell proliferation through photo-induced cytotoxic activity. Cell. Prolif., 2012, 45(1),9-47.
    • (2012) Cell. Prolif. , vol.45 , Issue.1 , pp. 9-47
    • Menichini, G.1    Alfano, C.2    Provenzano, E.3    Marrelli, M.4    Statti, G.A.5    Menichini, F.6    Conforti, F.7
  • 234
    • 77956927110 scopus 로고    scopus 로고
    • Photodynamic therapy: Illuminating the road from cell death towards anti-Tumor immunity
    • Garg, A.D.; Nowis, D.; Golab, J.; Agostinis, P. Photodynamic therapy: illuminating the road from cell death towards anti-Tumor immunity. Apoptosis, 2010, 15(9), 1050-1071.
    • (2010) Apoptosis , vol.15 , Issue.9 , pp. 1050-1071
    • Garg, A.D.1    Nowis, D.2    Golab, J.3    Agostinis, P.4
  • 236
    • 67650364257 scopus 로고    scopus 로고
    • Enhanced systemic immune reactivity to a basal cell carcinoma associated antigen following photodynamic therapy
    • Kabingu, E.; Oseroff, A.R.; Wilding, G.E.; Gollnick, S.O. Enhanced systemic immune reactivity to a Basal cell carcinoma associated antigen following photodynamic therapy. Clin. Cancer Res., 2009, 15(13), 4460-4466.
    • (2009) Clin. Cancer Res. , vol.15 , Issue.13 , pp. 4460-4466
    • Kabingu, E.1    Oseroff, A.R.2    Wilding, G.E.3    Gollnick, S.O.4
  • 237
    • 0028145560 scopus 로고
    • Antitumor immunity induced by photodynamic therapy with aluminum disulfonated phthalocyanines and laser light
    • Canti, G.; Lattuada, D.; Nicolin, A.; Taroni, P.; Valentini G., Cubeddu, R. Antitumorimmunity induced by photodynamic therapy with aluminium disulfonated phthalocyanines and laser light, Anti-Cancer Drugs, 1994, 5(4), 443-447. (Pubitemid 24237076)
    • (1994) Anti-Cancer Drugs , vol.5 , Issue.4 , pp. 443-447
    • Canti, G.1    Lattuada, D.2    Nicolin, A.3    Taroni, P.4    Valentini, G.5    Cubeddu, R.6
  • 238
    • 77949423008 scopus 로고    scopus 로고
    • Enhancement of anti-Tumor immunity by photodynamic therapy
    • Gollnick, S.O.; Brackett, C.M. Enhancement of anti-Tumor immunity by photodynamic therapy. Immunol. Res., 2009, 46(1-3), 216-226.
    • (2009) Immunol. Res. , vol.46 , Issue.1-3 , pp. 216-226
    • Gollnick, S.O.1    Brackett, C.M.2
  • 239
    • 79955553859 scopus 로고    scopus 로고
    • Cancer vaccines generated by photodynamic therapy
    • Korbelik, M. Cancer vaccines generated by photodynamic therapy. Photochem. Photobiol. Sci., 2011, 10(5), 664-669.
    • (2011) Photochem. Photobiol. Sci. , vol.10 , Issue.5 , pp. 664-669
    • Korbelik, M.1
  • 240
    • 79955601064 scopus 로고    scopus 로고
    • Adverse effects of topical photodynamic therapy
    • Ibbotson, S.H. Adverse effects of topical photodynamic therapy. Photodermatol. Photoimmunol. Photomed., 2011, 27(3), 116-130.
    • (2011) Photodermatol. Photoimmunol. Photomed. , vol.27 , Issue.3 , pp. 116-130
    • Ibbotson, S.H.1
  • 241
    • 56549129972 scopus 로고    scopus 로고
    • British association of dermatologists therapy guidelines and audit subcommittee and the british photodermatology group. Guidelines for topical photodynamic therapy: Update
    • Morton, C.A.; McKenna, K.E.; Rhodes, L.E. British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group. Guidelines for topical photodynamic therapy: update. Br. J. Dermatol., 2008, 159(6), 1245-1266.
    • (2008) Br. J. Dermatol. , vol.159 , Issue.6 , pp. 1245-1266
    • Morton, C.A.1    McKenna, K.E.2    Rhodes, L.E.3
  • 243
    • 77952551346 scopus 로고    scopus 로고
    • Oncologic photodynamic therapy photosensitizers: A clinical review
    • Allison, R.R.; Sibata, C.H. Oncologic photodynamic therapy photosensitizers: a clinical review. Photodiagnosis Photodyn. Ther., 2010, 7(2), 61-75.
    • (2010) Photodiagnosis Photodyn. Ther. , vol.7 , Issue.2 , pp. 61-75
    • Allison, R.R.1    Sibata, C.H.2


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