Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells

Toxicology

Volumn 285, Issue 3, 2011, Pages 97-103

  Wu, Dalei ^a   Wong, Patrick ^a   Li, Wen ^a   Vogel, Christoph F ^a   Matsumura, Fumio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

5 Aza 2' deoxycytidine; AHR; DNA methylation; ER ; MCF10AT1; WIF 1

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AROMATIC HYDROCARBON RECEPTOR; BETA CATENIN; ESTROGEN RECEPTOR ALPHA;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; DEMETHYLATION; DNA METHYLATION; DRUG EFFECT; EPIGENETICS; GENE; GENE REPRESSION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION; WIF 1 GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METHYLATION; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TCF TRANSCRIPTION FACTORS;

EID: 79957876145     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.04.008     Document Type: Article

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