Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway

FASEB Journal

Volumn 26, Issue 2, 2012, Pages 778-787

  Hsieh, Tsung Hua ^a   Tsai, Cheng Fang ^a   Hsu, Chia Yi ^a   Kuo, Po Lin ^a,b   Lee, Jau Nan ^b   Chai, Chee Yin ^b   Wang, Shao Chun ^c   Tsai, Eing Mei ^a,b,d  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Aryl hydrocarbon receptor; Environmental hormone; ER negative; Histone deacetylase 6; Nongenomic

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BETA CATENIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTROGEN RECEPTOR; HISTONE DEACETYLASE 6; LYMPHOID ENHANCER FACTOR 1; MYC PROTEIN; N BUTYLBENZYLPHTHALATE; PHTHALIC ACID; PHTHALIC ACID DIBUTYL ESTER; PROTEIN TCF4; TCF4, PKA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER INVASION; CELL GROWTH; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TUMOR GROWTH; UPREGULATION;

BREAST NEOPLASMS; CARCINOGENS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; HISTONE DEACETYLASES; HUMANS; NEOPLASM INVASIVENESS; PHTHALIC ACIDS; PLASTICIZERS; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, ARYL HYDROCARBON; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION;

EID: 84863017101     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-191742     Document Type: Article

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