Polymeric black tea polyphenols modulate the localization and activity of 12-O-tetradecanoylphorbol-13-acetate-mediated kinases in mouse skin: Mechanisms of their anti-tumor-promoting action

Free Radical Biology and Medicine

Volumn 53, Issue 6, 2012, Pages 1358-1370

  Kumar, Gaurav ^a   Dange, Prerana ^a   Kailaje, Vaishali ^a   Vaidya, Milind M ^a   Ramchandani, Asha G ^a   Maru, Girish B ^a  

^a TATA MEMORIAL HOSPITAL   (India)

Author keywords

Apoptosis; Free radicals; NF B; Phosphorylation; PI3K PDK1 AKT1; PKC; Polymeric black tea polyphenols; Proliferation; Signal transduction; TPA; Tumor promotion

Indexed keywords

BLACK TEA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PHOSPHOTRANSFERASE; POLYMERIC BLACK TEA POLYPHENOL; POLYMERIC BLACK TEA POLYPHENOL 3; POLYMERIC BLACK TEA POLYPHENOL 5; POLYPHENOL DERIVATIVE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FEMALE; FLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SKIN INFLAMMATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS REGULATORY PROTEINS; CAMELLIA SINENSIS; CARCINOGENS; CELL LINE; CELL PROLIFERATION; CURCUMIN; FEMALE; HUMANS; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PLANT EXTRACTS; PLANT LEAVES; POLYPHENOLS; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SKIN; TETRADECANOYLPHORBOL ACETATE;

CAMELLIA SINENSIS;

EID: 84865430034     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.017     Document Type: Article

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