A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Coppé, Jean Philippe ^a,b   Patil, Christopher K ^a,b   Rodier, Francis ^a,b,f   Krtolica, Ana ^a,g   Beauséjour, Christian M ^c   Parrinello, Simona ^a,h   Hodgson, J Graeme ^d,i   Chin, Koei ^d   Desprez, Pierre Yves ^a,b,e   Campisi, Judith ^a,b  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c UNIVERSITY OF MONTREAL   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^f UNIVERSITÉ DE MONTRÉAL   (Canada)

^g StemLifeLine Inc   (United States)

^h UNIVERSITY COLLEGE LONDON   (United Kingdom)

ⁱ PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; MATRIX METALLOPROTEINASE; OXYGEN; INTERLEUKIN 6; PROTEOME; SIGNAL PEPTIDE; SOMATOMEDIN BINDING PROTEIN 6; TRP53BP1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL AGING; CELL CULTURE; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; EPITHELIUM CELL; FIBROBLAST; GENOMICS; HUMAN; MOUSE; NONHUMAN; PHENOTYPE; ANIMAL; C57BL MOUSE; DNA DAMAGE; EXPERIMENTAL NEOPLASM; GENETICS; GENOMIC INSTABILITY; METABOLISM; METHODOLOGY; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION; SPECIES DIFFERENCE; TUMOR VOLUME; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CELL AGING; CELLS, CULTURED; DNA DAMAGE; EPITHELIAL CELLS; FIBROBLASTS; GENOMIC INSTABILITY; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; OXYGEN; PHENOTYPE; PROTEOME; PROTEOMICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN;

EID: 77949458344     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009188     Document Type: Article

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