The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: A 30-year prospective study

Journal of the American Academy of Dermatology

Volumn 66, Issue 4, 2012, Pages 553-562

  Stern, Robert S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

basal cell cancer; binomial regression; cohort study; Cox proportional hazard; prospective; psoralen plus ultraviolet A; psoriasis; risk factors; squamous cell cancer

Indexed keywords

METHOTREXATE;

ADULT; ARTICLE; BASAL CELL CARCINOMA; CANCER INCIDENCE; CANCER LOCALIZATION; CANCER RISK; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PSORIASIS; PUVA; SKIN BIOPSY; SKIN CANCER; SQUAMOUS CELL CARCINOMA;

ADULT; CARCINOMA, BASAL CELL; FEMALE; HUMANS; MALE; NEOPLASMS, BASAL CELL; PROSPECTIVE STUDIES; PSORIASIS; PUVA THERAPY; RISK FACTORS; SKIN NEOPLASMS; TIME FACTORS;

EID: 84858335295     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2011.04.004     Document Type: Article

References (27)

1. J. Parrish, T. Fitzpatrick, L. Tanenbaum, and M. Pathak Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light N Engl J Med 291 1974 1207 1211
2. R. Joseph, M. Shanthamma, F. Rehana, and K. Nana Induced mutations in Serratia marcescens by near UV-light in presence of psoralen Experientia 30 1974 360 361
3. J. Melski, L. Tanenbaum, J. Parrish, T. Fitzpatrick, and H. Bleich Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial J Invest Dermatol 68 1977 328 335
4. R. Stern, L. Thibodeau, R. Kleinerman, J. Parrish, and T. Fitzpatrick Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis N Engl J Med 300 1979 809 813
5. T. Henseler, E. Christophers, H. Hönigsmann, and K. Wolff Skin tumors in the European PUVA study: eight-year follow-up of 1,643 patients treated with PUVA for psoriasis J Am Acad Dermatol 16 1987 108 116
6. B. Lindelöf, B. Sigurgeirsson, E. Tegner, O. Larkö, A. Johannesson, and B. Berne PUVA and cancer: a large-scale epidemiological study Lancet 338 1991 91 93
7. B. Lindelöf, B. Sigurgeirsson, E. Tegner, O. Larkö, A. Johannesson, and B. Berne PUVA and cancer: the Swedish follow-up study Br J Dermatol 141 1999 108 112
8. I. Bruynzeel, W. Bergman, H. Hartevelt, C. Kenter, E. Van de Velde, and A. Schothorst 'High single-dose' European PUVA regimen also causes an excess of non-melanoma skin cancer Br J Dermatol 124 1991 49 55
9. R. Stern, N. Laird, J. Melski, J. Parrish, T. Fitzpatrick, and H. Bleich Cutaneous squamous-cell carcinoma in patients treated with PUVA N Engl J Med 310 1984 1156 1161
10. R. Stern Genital tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation: the photochemotherapy follow-up study N Engl J Med 322 1990 1093 1097
11. R. Stern, and N. Laird The carcinogenic risk of treatments for severe psoriasis: photochemotherapy follow-up study Cancer 73 1994 2759 2764
12. R. Stern, and K. Nichols Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma: the PUVA follow-up study J Pediatr 129 1996 915 917
13. R. Stern, E. Liebman, and L. Väkevä Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer: PUVA follow-up study J Natl Cancer Inst 90 1998 1278 1284
14. R. Stern, and E. Lunder Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA): a meta-analysis Arch Dermatol 134 1998 1582 1585
15. T. Nijsten, and R. Stern The increased risk of skin cancer is persistent after discontinuation of psoralen+ultraviolet A: a cohort study J Invest Dermatol 121 2003 252 258
16. R. Stern Prevalence of a history of skin cancer in 2007 Arch Dermatol 146 2010 279 282
17. R. Stern, and A. Hibregste Very severe psoriasis is associated with increased noncardiovascular mortality but not with increased cardiovascular risk J Invest Dermatol 131 2011 1159 1166
18. I. Marcil, and R. Stern Squamous-cell cancer of the skin in patients given PUVA and cyclosporin: nested cohort crossover study Lancet 358 2001 1042 1045
19. V. Madan, J. Lear, and R. Szeimies Non-melanoma skin cancer Lancet 375 2010 673 685
20. M. Karagas, J. McDonald, R. Greenberg, T. Stukel, J. Weiss, and J. Barron Risk of basal cell skin cancers after ionizing radiation therapy J Natl Cancer Inst 88 1996 1848 1853
21. M. Karagas, H. Nelson, M. Zens, M. Linet, T. Stukel, and S. Spencer Squamous cell and basal cell carcinoma of the skin in relation to radiation therapy and potential modification of risk by sun exposure Epidemiology 18 2007 776 784
22. C. Kennedy, C. Bajdik, R. Willemze, F. de Gruijl, and J. Bouwes Bavinck The influence of painful sunburns and lifetime sun exposure on the risk of actinic keratoses, seborrheic warts, melanocytic nevi, atypical nevi, and skin cancer J Invest Dermatol 120 2003 1087 1093
23. J. Han, G. Colditz, and D. Hunter Risk factors for skin cancers: a nested case-control study within the nurses' health study Int J Epidemiol 35 2006 1514 1521
24. K. Brantsch, C. Meisner, B. Schönfisch, B. Trilling, J. Wehner-Caroli, and M. Röcken Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study Lancet 9 2008 713 720
25. T. Diepgen, and V. Mahler The epidemiology of skin cancer Br J Dermatol 146 2002 1 6
26. K. Lewis, and M. Weinstock Nonmelanoma skin cancer mortality (1988-2000): the Rhode Island follow-back study Arch Dermatol 140 2004 837 842
27. H. Rogers, M. Weinstock, A. Harris, M. Hinckley, S. Reldman, and A. Fleischer Incidence estimate of nonmelanoma skin cancer in the United States, 2006 Arch Dermatol 146 2010 283 287