Both Rb/p16(INK4a) inactivation and telomerase activity are required to immortalize human epithelial cells

Nature

Volumn 396, Issue 6706, 1998, Pages 84-88

  Kiyono, Tohru ^a,b   Foster, Scott A ^a   Koop, Jenn I ^a   McDougall, James K ^a   Galloway, Denise A ^a   Klingelhutz, Aloysius J ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; ONCOPROTEIN; TELOMERASE; DNA BINDING PROTEIN; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; PROTEIN; PROTEIN P16INK4A; REPRESSOR PROTEIN; RETINOBLASTOMA PROTEIN; RNA; TELOMERASE RNA;

ARTICLE; CELL IMMORTALIZATION; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; KERATINOCYTE; ONCOGENE; PRIORITY JOURNAL; SENESCENCE; TELOMERE; WART VIRUS; BREAST; CELL AGING; CELL CULTURE; CELL TRANSFORMATION; CYTOLOGY; DRUG ANTAGONISM; ENZYME INDUCTION; PHYSIOLOGY; VIRUS CELL TRANSFORMATION;

BREAST; CELL AGING; CELL TRANSFORMATION, NEOPLASTIC; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA-BINDING PROTEINS; ENZYME INDUCTION; HUMANS; KERATINOCYTES; ONCOGENE PROTEINS, VIRAL; PROTEINS; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; RNA; TELOMERASE;

EID: 0032487675     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/23962     Document Type: Article

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