Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

Experimental Cell Research

Volumn 295, Issue 2, 2004, Pages 525-538

  Munro, June ^a   Barr, Nighean I ^a   Ireland, Hazel ^a   Morrison, Vivienne ^a   Parkinson, E Kenneth ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Butyrate; Chromatin; INK4A; p53; pRb; Senescence; Telomerase

Indexed keywords

ARF PROTEIN; BUTYRIC ACID DERIVATIVE; HISTONE DEACETYLASE INHIBITOR; PROTEIN E6; PROTEIN P14; PROTEIN P16; PROTEIN P21; PROTEIN P53; SODIUM DIBUTYRATE; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL AGING; CELL CYCLE; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; FETUS; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; SENESCENCE; SEQUENTIAL ANALYSIS; TELOMERE; UPREGULATION; WART VIRUS;

HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; PAPILLOMAVIRUS;

EID: 1842861744     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.01.017     Document Type: Article

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